45 research outputs found

    Correlation and regression studies in semi-dwarf spring wheat (Triticum aestivum L)

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    Correlation and regression studies in semi-dwarf spring wheat (Triticum aestivum L)

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    Relatório de estágio do mestrado em Gestão, apresentada à Faculdade de Economia da Universidade de Coimbra, sob a orientação de José Vaz Ferreira e Edgar Saraiva.O presente trabalho apresenta-se como relatório de estágio do Mestrado em Gestão da Faculdade de Economia da Universidade de Coimbra desenvolvido na entidade My Business Consultores Financeiros e Informáticos, Lda. O referido estágio realizou-se no período de 20 de Janeiro a 12 de Junho, do presente ano. O principal objectivo deste estágio passou por desempenhar um conjunto de atividades integradas no processo contabilístico, permitiu-me identificar a existência de documentos contabilísticos, dos quais desconhecia a sua utilidade e elaboração, tendo sido um deles a demonstração de fluxos de caixa. A conveniência em dominar esta “nova” demonstração suscita o interesse para o seu estudo, por forma a conhecer o processo de elaboração e de que modo a informação que se retira da sua análise influência a tomada de decisão. A maioria dos empresários analisa exaustivamente a demonstração de resultados e o balanço, esquecendo-se, ou dando pouco atenção, à demonstração de fluxos de caixa. Esta atitude pode ser considerada errónea, uma vez que a análise a partir do cálculo de rácios financeiros e fluxos de caixa tem-se revelado uma ótima ferramenta estratégica de gestão, não só por avaliar a continuidade de uma empresa como também a sua posição financeira. Assim, o presente estudo revela a importância da elaboração da demonstração de fluxos de caixa através da identificação do interesse da sua divulgação, da compreensão da natureza dos seus fluxos e a importância da avaliação destes para a proteção da saúde financeira de uma empresa. Na aplicação prática deste estudo foi realizada uma ferramenta que tem como funcionalidade elaborar, de forma automática, a demonstração de fluxos de caixa pelo método direto e calcular os principais rácios relativos aos fluxos de caixa obtidos. Esta ferramenta tem o objetivo de retirar toda a informação pertinente da demonstração dos fluxos de caixa e posteriormente uni-la com a informação retirada das outras demonstrações, de modo a obter a informação mais fiável possível, para uma tomada de decisões acertada

    Coleoptile length studies in semi-dwarf wheat (Triticum aestivum L.) with different dwarfing genes

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    Towards the Development of an Empirical Model for Islamic Corporate Social Responsibility: Evidence from the Middle East

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    Academic research suggests that variances in contextual dynamics, and more specifically religion, may lead to disparate perceptions and practices of corporate social responsibility (CSR). Driven by the increased geopolitical and economic importance of the Middle East and identified gaps in knowledge, the study aims to examine if indeed there is a divergent form of CSR exercised in the region. The study identifies unique CSR dimensions and constructs presented through an empirical framework in order to outline the practice and perception of CSR in a context with strong Islamic beliefs. The framework goes beyond the platform of mere Islamic philanthropy and is based on CSR-stakeholder management practices. Following an exploratory research design and collecting interview data from representatives of 63 organisations from Saudi Arabia, the United Arab Emirates and Oman, the study offers a snapshot of the CSR reality from the perspective of those living the phenomenon. The results suggest that the practice and perception of CSR in the examined context are largely grounded in the areas of social and altruistic actions but they cannot be examined in isolation from the religious context of CSR operation. This focus is mainly attributed to the dominant role of Islam in the examined sample, which leads to forms of non-structured or semi-structured approaches to CSR. Apart from the theoretical advancements offered to the CSR literature, the study also provides contributions for practitioners and policy makers.</p

    Functional Variant in Complement C3 Gene Promoter and Genetic Susceptibility to Temporal Lobe Epilepsy and Febrile Seizures

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    BACKGROUND: Human mesial temporal lobe epilepsies (MTLE) represent the most frequent form of partial epilepsies and are frequently preceded by febrile seizures (FS) in infancy and early childhood. Genetic associations of several complement genes including its central component C3 with disorders of the central nervous system, and the existence of C3 dysregulation in the epilepsies and in the MTLE particularly, make it the C3 gene a good candidate for human MTLE. METHODOLOGY/PRINCIPAL FINDINGS: A case-control association study of the C3 gene was performed in a first series of 122 patients with MTLE and 196 controls. Four haplotypes (HAP1 to 4) comprising GF100472, a newly discovered dinucleotide repeat polymorphism [(CA)8 to (CA)15] in the C3 promoter region showed significant association after Bonferroni correction, in the subgroup of MTLE patients having a personal history of FS (MTLE-FS+). Replication analysis in independent patients and controls confirmed that the rare HAP4 haplotype comprising the minimal length allele of GF100472 [(CA)8], protected against MTLE-FS+. A fifth haplotype (HAP5) with medium-size (CA)11 allele of GF100472 displayed four times higher frequency in controls than in the first cohort of MTLE-FS+ and showed a protective effect against FS through a high statistical significance in an independent population of 97 pure FS. Consistently, (CA)11 allele by its own protected against pure FS in a second group of 148 FS patients. Reporter gene assays showed that GF100472 significantly influenced C3 promoter activity (the higher the number of repeats, the lower the transcriptional activity). Taken together, the consistent genetic data and the functional analysis presented here indicate that a newly-identified and functional polymorphism in the promoter of the complement C3 gene might participate in the genetic susceptibility to human MTLE with a history of FS, and to pure FS. CONCLUSIONS/SIGNIFICANCE: The present study provides important data suggesting for the first time the involvement of the complement system in the genetic susceptibility to epileptic seizures and to epilepsy

    Synthesising Corporate Responsibility on Organisational and Societal Levels of Analysis: An Integrative Perspective

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    This article develops an integrative perspective on corporate responsibility by synthesising competing perspectives on the responsibility of the corporation at the organisational and societal levels of analysis. We review three major corporate responsibility perspectives, which we refer to as economic, critical, and politico-ethical. We analyse the major potential uses and pitfalls of the perspectives, and integrate the debate on these two levels. Our synthesis concludes that when a society has a robust division of moral labour in place, the responsibility of a corporation may be economic (as suggested under the economic perspective) without jeopardising democracy and sustainability (as reported under the critical perspective). Moreover, the economic role of corporations neither signifies the absence of deliberative democratic mechanisms nor business practices extending beyond compliance (as called for under the politico-ethical perspective). The study underscores the value of integrating different perspectives and multiple levels of analysis to present comprehensive descriptions and prescriptions of the responsibility phenomenon

    Notes for genera: basal clades of Fungi (including Aphelidiomycota, Basidiobolomycota, Blastocladiomycota, Calcarisporiellomycota, Caulochytriomycota, Chytridiomycota, Entomophthoromycota, Glomeromycota, Kickxellomycota, Monoblepharomycota, Mortierellomycota, Mucoromycota, Neocallimastigomycota, Olpidiomycota, Rozellomycota and Zoopagomycota)

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    Compared to the higher fungi (Dikarya), taxonomic and evolutionary studies on the basal clades of fungi are fewer in number. Thus, the generic boundaries and higher ranks in the basal clades of fungi are poorly known. Recent DNA based taxonomic studies have provided reliable and accurate information. It is therefore necessary to compile all available information since basal clades genera lack updated checklists or outlines. Recently, Tedersoo et al. (MycoKeys 13:1--20, 2016) accepted Aphelidiomycota and Rozellomycota in Fungal clade. Thus, we regard both these phyla as members in Kingdom Fungi. We accept 16 phyla in basal clades viz. Aphelidiomycota, Basidiobolomycota, Blastocladiomycota, Calcarisporiellomycota, Caulochytriomycota, Chytridiomycota, Entomophthoromycota, Glomeromycota, Kickxellomycota, Monoblepharomycota, Mortierellomycota, Mucoromycota, Neocallimastigomycota, Olpidiomycota, Rozellomycota and Zoopagomycota. Thus, 611 genera in 153 families, 43 orders and 18 classes are provided with details of classification, synonyms, life modes, distribution, recent literature and genomic data. Moreover, Catenariaceae Couch is proposed to be conserved, Cladochytriales Mozl.-Standr. is emended and the family Nephridiophagaceae is introduced

    Concepts of the mode of action and toxicity of anti-inflammatory drugs. A basis for safer and more selective therapy, and for future drug developments

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