End-to-end Recovery of Human Shape and Pose

We describe Human Mesh Recovery (HMR), an end-to-end framework for reconstructing a full 3D mesh of a human body from a single RGB image. In contrast to most current methods that compute 2D or 3D joint locations, we produce a richer and more useful mesh representation that is parameterized by shape and 3D joint angles. The main objective is to minimize the reprojection loss of keypoints, which allow our model to be trained using images in-the-wild that only have ground truth 2D annotations. However, the reprojection loss alone leaves the model highly under constrained. In this work we address this problem by introducing an adversary trained to tell whether a human body parameter is real or not using a large database of 3D human meshes. We show that HMR can be trained with and without using any paired 2D-to-3D supervision. We do not rely on intermediate 2D keypoint detections and infer 3D pose and shape parameters directly from image pixels. Our model runs in real-time given a bounding box containing the person. We demonstrate our approach on various images in-the-wild and out-perform previous optimization based methods that output 3D meshes and show competitive results on tasks such as 3D joint location estimation and part segmentation.Comment: CVPR 2018, Project page with code: https://akanazawa.github.io/hmr

Monetary benefits of preventing childhood lead poisoning with lead-safe window replacement

Previous estimates of childhood lead poisoning prevention benefits have quantified the present value of some health benefits, but not the costs of lead paint hazard control or the benefits associated with housing and energy markets. Because older housing with lead paint constitutes the main exposure source today in the U.S., we quantify health benefits, costs, market value benefits, energy savings, and net economic benefits of lead-safe window replacement (which includes paint stabilization and other measures). The benefit per resident child from improved lifetime earnings alone is $21,195 in pre-1940 housing and$8,685 in 1940-59 housing (in 2005 dollars). Annual energy savings are $130 to$486 per housing unit, with or without young resident children, with an associated increase in housing market value of $5,900 to$14,300 per housing unit, depending on home size and number of windows replaced. Net benefits are $4,490 to$5,629 for each housing unit built before 1940, and $491 to$1,629 for each unit built from 1940-1959, depending on home size and number of windows replaced. Lead-safe window replacement in all pre-1960 U.S. housing would yield net benefits of at least $67 billion, which does not include many other benefits. These other benefits, which are shown in this paper, include avoided Attention Deficit Hyperactivity Disorder, other medical costs of childhood lead exposure, avoided special education, and reduced crime and juvenile delinquency in later life. In addition, such a window replacement effort would reduce peak demand for electricity, carbon emissions from power plants, and associated long-term costs of climate change.Lead Poisoning, IQ, Energy Efficiency, Cost Benefit Analysis, Housing, Climate Change

Characterizing Phenotypic Differences between Two Clades of Influenza A Viruses from the 2016-17 and 2017-18 U.S. Flu Seasons

The severity of the influenza outbreak in the United States during the 2017-18 season surpassed that of the 2016-17 season, with a case load reminiscent of the H1N1 pandemic of 2009-10. This increase in severity occurred despite the fact that both seasons’ H3N2 vaccine strain, derived from a clade 3C.2a virus, was from the same clade as the most commonly circulating viruses. Previous work conducted in the Pekosz laboratory determined that, between the 2016-17 and 2017-18 seasons, viruses of the 3C.2a1 clade reassorted with both 3C.2a2 and 3C.3a viruses. It was hypothesized that these reassortments might have contributed to the observed increase in virulence during the 2017-18 season. The results of these studies showed that 3C.3a viruses from both the 2016-17 and 2017-18 seasons, including the reassortant 3C.3a viruses, replicated to higher titers at earlier times post-infection in both immortalized cells and primary cell cultures than 3C.2a1 viruses. Additionally, 2017-18 3C.3a reassortant viruses produced larger plaques than either 2016-17 3C.2a1 or 3C.3a viruses. Taken together, these results suggest that 3C.3a reassortant viruses obtained a fitness advantage over the 3C.2a1 parental strain. To determine which gene segments were associated with this increased fitness, 3C.2a1 viruses with gene segments from the 2016-17 season and a single gene segment from the reassorted 3C.3a virus – either HA, M or NS – were clonally generated and examined for their replication phenotypes. An initial MDCK-Siat growth curve conducted with rescued monoreassortant 3C.2a1 viruses containing either 3C.3a HA, M or NS from the 2017-18 reassortant 3C.3a clade showed that the 3C.2a1 virus bearing the 3C.3a HA gene segment best recapitulated the phenotype of the 2017-18 3C.3a reassortant virus, suggesting that the HA gene segment is contributing substantially to the difference in the phenotype observed between the 3C.3a and 3C.2a1 clades

Three-Dimensionally Preserved Integument Reveals Hydrodynamic Adaptations in the Extinct Marine Lizard Ectenosaurus (Reptilia, Mosasauridae)

The physical properties of water and the environment it presents to its inhabitants provide stringent constraints and selection pressures affecting aquatic adaptation and evolution. Mosasaurs (a group of secondarily aquatic reptiles that occupied a broad array of predatory niches in the Cretaceous marine ecosystems about 98–65 million years ago) have traditionally been considered as anguilliform locomotors capable only of generating short bursts of speed during brief ambush pursuits. Here we report on an exceptionally preserved, long-snouted mosasaur (Ectenosaurus clidastoides) from the Santonian (Upper Cretaceous) part of the Smoky Hill Chalk Member of the Niobrara Formation in western Kansas, USA, that contains phosphatized remains of the integument displaying both depth and structure. The small, ovoid neck and/or anterior trunk scales exhibit a longitudinal central keel, and are obliquely arrayed into an alternating pattern where neighboring scales overlap one another. Supportive sculpturing in the form of two parallel, longitudinal ridges on the inner scale surface and a complex system of multiple, superimposed layers of straight, cross-woven helical fiber bundles in the underlying dermis, may have served to minimize surface deformation and frictional drag during locomotion. Additional parallel fiber bundles oriented at acute angles to the long axis of the animal presumably provided stiffness in the lateral plane. These features suggest that the anterior torso of Ectenosaurus was held somewhat rigid during swimming, thereby limiting propulsive movements to the posterior body and tail

Super-orbital re-entry in Australia - laboratory measurement, simulation and flight observation

There are large uncertainties in the aerothermodynamic modelling of super-orbital re-entry which impact the design of spacecraft thermal protection systems (TPS). Aspects of the thermal environment of super-orbital re-entry flows can be simulated in the laboratory using arc- and plasma jet facilities and these devices are regularly used for TPS certification work [5]. Another laboratory device which is capable of simulating certain critical features of both the aero and thermal environment of super-orbital re-entry is the expansion tube, and three such facilities have been operating at the University of Queensland in recent years[10]. Despite some success, wind tunnel tests do not achieve full simulation, however, a virtually complete physical simulation of particular re-entry conditions can be obtained from dedicated flight testing, and the Apollo era FIRE II flight experiment [2] is the premier example which still forms an important benchmark for modern simulations. Dedicated super-orbital flight testing is generally considered too expensive today, and there is a reluctance to incorporate substantial instrumentation for aerothermal diagnostics into existing missions since it may compromise primary mission objectives. An alternative approach to on-board flight measurements, with demonstrated success particularly in the ‘Stardust’ sample return mission, is remote observation of spectral emissions from the capsule and shock layer [8]. JAXA’s ‘Hayabusa’ sample return capsule provides a recent super-orbital reentry example through which we illustrate contributions in three areas: (1) physical simulation of super-orbital re-entry conditions in the laboratory; (2) computational simulation of such flows; and (3) remote acquisition of optical emissions from a super-orbital re entry event

Associations of body composition measures and C2, a marker for small artery elasticity: The MESA.

ObjectiveLower C2, a continuous blood pressure waveform characteristic asserted to represent small artery elasticity, predicts future cardiovascular disease events. It is hypothesized that the paradoxical positive association between body mass index (BMI) and C2 may reflect muscle instead of excess fat.MethodsIn a multi-ethnic, community-living cohort of 1,960 participants, computed tomography scans of the abdomen were used to measure visceral adipose tissue (VAT) and total abdominal muscle tissue (TAMT), and applanation tonometry of the radial arteries was used to assess C2. The period cross-sectional associations between BMI, TAMT, and VAT with C2 were ascertained.ResultsThe mean age was 62 ± 9 years and 51% were male. After adjustments for age, gender, ethnicity, pack years smoking cigarettes, diabetes, hypertension, and total and HDL cholesterol, higher BMI (standardized beta = 0.09, P-value < 0.01) and more TAMT (standardized beta = 0.12, P-value < 0.01) were significantly associated with higher C2. In contrast, more VAT (standardized beta = -0.09, P-value < 0.01) was associated with lower C2.ConclusionsIn multivariable analysis, VAT, in contrast to TAMT and BMI, was associated with less compliant small arteries. Visceral fat may be a better marker for detrimental excess body fat than BMI