Extensibility and rheology of collenchyma I. Creep relaxation and viscoelasticity of young and senescent cells

The extensibility of collenchyma cells was methodologically analyzed; extensibility (elasticity and plasticity) and rheology of this tissue are discussed. Experimental conditions are described. Rheological data for young and senescent cells were obtained; they were found to be not Boltzmannian. The permanent strain is not viscous, and is larger for young cells than older one

Extensibility and rheology of collenchyma cells: II. Low-pH effect on the extension of collocytes isolated from high- and low-growing material

Low-pH effects were studied on the extension of isolated fresh, methanol-killed and frozen-thawed collocytes. Fresh and frozen-thawed samples responded to low pH. This response decreased with increasing differentiation. A yield stress was found for frozen-thawed samples. The significance of the response during growth and differentiation is discusse

Conceptualizing human resilience in the face of the global epidemiology of cyber attacks

Computer security is a complex global phenomenon where different populations interact, and the infection of one person creates risk for another. Given the dynamics and scope of cyber campaigns, studies of local resilience without reference to global populations are inadequate. In this paper we describe a set of minimal requirements for implementing a global epidemiological infrastructure to understand and respond to large-scale computer security outbreaks. We enumerate the relevant dimensions, the applicable measurement tools, and define a systematic approach to evaluate cyber security resilience. From the experience in conceptualizing and designing a cross-national coordinated phishing resilience evaluation we describe the cultural, logistic, and regulatory challenges to this proposed public health approach to global computer assault resilience. We conclude that mechanisms for systematic evaluations of global attacks and the resilience against those attacks exist. Coordinated global science is needed to address organised global ecrime

International comparison of health care carbon footprints

Climate change confronts the health care sector with a dual challenge. Accumulating climate impacts are putting an increased burden on the service provision of already stressed health care systems in many regions of the world. At the same time, the Paris agreement requires rapid emission reductions in all sectors of the global economy to stay well below the 2 °C target. This study shows that in OECD countries, China, and India, health care on average accounts for 5% of the national CO2 footprint making the sector comparable in importance to the food sector. Some countries have seen reduced CO2 emissions related to health care despite growing expenditures since 2000, mirroring their economy wide emission trends. The average per capita health carbon footprint across the country sample in 2014 was 0.6 tCO2, varying between 1.51 tCO2/cap in the US and 0.06 tCO2/cap in India. A statistical analysis shows that the carbon intensity of the domestic energy system, the energy intensity of the domestic economy, and health care expenditure together explain half of the variance in per capita health carbon footprints. Our results indicate that important leverage points exist inside and outside the health sector. We discuss our findings in the context of the existing literature on the potentials and challenges of reducing GHG emissions in the health and energy sector

The energy and carbon inequality corridor for a 1.5 °C compatible and just Europe

The call for a decent life for all within planetary limits poses a dual challenge: provide all people with the essential resources needed to live well and, collectively, not exceed the source and sink capacity of the biosphere to sustain human societies. We examine the corridor of possible distributions of household energy and carbon footprints that satisfy both minimum energy use for a decent life and available energy supply compatible with the 1.5 °C target in 2050. We estimated household energy and carbon footprints for expenditure deciles for 28 European countries in 2015 by combining data from national household budget surveys with the environmentally-extended multi-regional input–output model EXIOBASE. We found a top-to-bottom decile ratio (90:10) of 7.2 for expenditure, 3.1 for net energy and 2.6 for carbon. The lower inequality of energy and carbon footprints is largely attributable to inefficient energy and heating technologies in the lower deciles (mostly Eastern Europe). Adopting best technology across Europe would save 11 EJ of net energy annually, but increase environmental footprint inequality. With such inequality, both targets can only be met through the use of CCS, large efficiency improvements, and an extremely low minimum final energy use of 28 GJ per adult equivalent. Assuming a more realistic minimum energy use of about 55 GJ ae−1 and no CCS deployment, the 1.5 °C target can only be achieved at near full equality. We conclude that achieving both stated goals is an immense and widely underestimated challenge, the successful management of which requires far greater room for maneuver in monetary and fiscal terms than is reflected in the current European political discourse.Peer Reviewe

The energy and carbon inequality corridor for a 1.5 °C compatible and just Europe

The call for a decent life for all within planetary limits poses a dual challenge: provide all people with the essential resources needed to live well and, collectively, not exceed the source and sink capacity of the biosphere to sustain human societies. We examine the corridor of possible distributions of household energy and carbon footprints that satisfy both minimum energy use for a decent life and available energy supply compatible with the 1.5 °C target in 2050. We estimated household energy and carbon footprints for expenditure deciles for 28 European countries in 2015 by combining data from national household budget surveys with the environmentally-extended multi-regional input–output model EXIOBASE. We found a top-to-bottom decile ratio (90:10) of 7.2 for expenditure, 3.1 for net energy and 2.6 for carbon. The lower inequality of energy and carbon footprints is largely attributable to inefficient energy and heating technologies in the lower deciles (mostly Eastern Europe). Adopting best technology across Europe would save 11 EJ of net energy annually, but increase environmental footprint inequality. With such inequality, both targets can only be met through the use of CCS, large efficiency improvements, and an extremely low minimum final energy use of 28 GJ per adult equivalent. Assuming a more realistic minimum energy use of about 55 GJ ae−1 and no CCS deployment, the 1.5 °C target can only be achieved at near full equality. We conclude that achieving both stated goals is an immense and widely underestimated challenge, the successful management of which requires far greater room for maneuver in monetary and fiscal terms than is reflected in the current European political discourse

International comparison of health care carbon footprints

Climate change confronts the health care sector with a dual challenge. Accumulating climate impacts are putting an increased burden on the service provision of already stressed health care systems in many regions of the world. At the same time, the Paris agreement requires rapid emission reductions in all sectors of the global economy to stay well below the 2 °C target. This study shows that in OECD countries, China, and India, health care on average accounts for 5% of the national CO2 footprint making the sector comparable in importance to the food sector. Some countries have seen reduced CO2 emissions related to health care despite growing expenditures since 2000, mirroring their economy wide emission trends. The average per capita health carbon footprint across the country sample in 2014 was 0.6 tCO2, varying between 1.51 tCO2/cap in the US and 0.06 tCO2/cap in India. A statistical analysis shows that the carbon intensity of the domestic energy system, the energy intensity of the domestic economy, and health care expenditure together explain half of the variance in per capita health carbon footprints. Our results indicate that important leverage points exist inside and outside the health sector. We discuss our findings in the context of the existing literature on the potentials and challenges of reducing GHG emissions in the health and energy sector.Austrian Climate Research ProgramPeer Reviewe

Segmentation and Modelling of the Nuclear Envelope of HeLa Cells Imaged with Serial Block Face Scanning Electron Microscopy

This paper describes an unsupervised algorithm, which segments the nuclear envelope of HeLa cells imaged by Serial Block Face Scanning Electron Microscopy. The algorithm exploits the variations of pixel intensity in different cellular regions by calculating edges, which are then used to generate superpixels. The superpixels are morphologically processed and those that correspond to the nuclear region are selected through the analysis of size, position, and correspondence with regions detected in neighbouring slices. The nuclear envelope is segmented from the nuclear region. The three-dimensional segmented nuclear envelope is then modelled against a spheroid to create a two-dimensional (2D) surface. The 2D surface summarises the complex 3D shape of the nuclear envelope and allows the extraction of metrics that may be relevant to characterise the nature of cells. The algorithm was developed and validated on a single cell and tested in six separate cells, each with 300 slices of 2000 × 2000 pixels. Ground truth was available for two of these cells, i.e., 600 hand-segmented slices. The accuracy of the algorithm was evaluated with two similarity metrics: Jaccard Similarity Index and Mean Hausdorff distance. Jaccard values of the first/second segmentation were 93%/90% for the whole cell, and 98%/94% between slices 75 and 225, as the central slices of the nucleus are more regular than those on the extremes. Mean Hausdorff distances were 9/17 pixels for the whole cells and 4/13 pixels for central slices. One slice was processed in approximately 8 s and a whole cell in 40 min. The algorithm outperformed active contours in both accuracy and time

Pressure Induced Change in the Magnetic Modulation of CeRhIn5

We report the results of a high pressure neutron diffraction study of the heavy fermion compound CeRhIn5 down to 1.8 K. CeRhIn5 is known to order magnetically below 3.8 K with an incommensurate structure. The application of hydrostatic pressure up to 8.6 kbar produces no change in the magnetic wave vector qm. At 10 kbar of pressure however, a sudden change in the magnetic structure occurs. Although the magnetic transition temperature remains the same, qm increases from (0.5, 0.5, 0.298) to (0.5, 0.5, 0.396). This change in the magnetic modulation may be the outcome of a change in the electronic character of this material at 10 kbar.Comment: 4 pages, 3 figures include