The safety benefit of retro-reflective markings on HGVs and buses: partial RIA – preliminary report.

The objective of the measure is to reduce death and serious injury resulting from collisions involving large vehicles. This will be achieved by making these vehicles more conspicuous to other road users, especially at night. This assessment estimates the costs and benefits associated with the proposal that hazard markings consistent with UNECE R104 should be required for all new heavy goods vehicles (HGVs) and buses under Regulation 48. The assessment considers commercial vehicles exceeding 3.5, 7.5 and 12 tonnes and on all new buses and coaches fitted with more than 22 passenger seats. The assessment was undertaken as a preparatory activity prior to formal consultation with relevant stakeholders

Assessment of the safety benefit of retro reflective markings on HGVs and buses.

Assessment of the safety benefit of retro reflective markings on HGVs and buses

Pennsylvania Folklife Vol. 19, No. 1

• The Moravian Settlements of Pennsylvania in 1757: The Nicholas Garrison Views • The San Rocco Festival at Aliquippa, Pennsylvania: A Transplanted Tradition • Amish Genealogy: A Progress Report • Pulpit Humor in Central Pennsylvania • The Pre-Metric Foot and its Use in Pennsylvania German Architecture • Mennonite Contacts Across the Atlantic: The Van der Smissen Letter of 1838 • Bread, Baking, and the Bakeoven: Folk-Cultural Questionnaire No. 13https://digitalcommons.ursinus.edu/pafolklifemag/1037/thumbnail.jp

New potent inhibitors of angiotensin converting enzyme

AbstractUsing an earlier model of the favoured orientation of binding functions of angiotensin converting enzyme (ACE) inhibitors, it has been possible to postulate a new, 7,6-bicyclic system, based on hexahydropyridazine, which might be expected to have high potency. Some members of this system which have been synthesised have been shown to be very active ACE inhibitors, in vitro and in vivo

Potent selective inhibitors of protein kinase C

AbstractA series of potent, selective inhibitors of protein kinase C has been derived from the structural lead provided by the microbial broth products, staurosporine and K252a. Our inhibitors block PCK in intact cells (platelets and T cells), and prevent the proliferation of mononuclear cells in response to interleukin 2 (IL2)