2,505 research outputs found
Searching for magnetic monopoles trapped in accelerator material at the Large Hadron Collider
If produced in high energy particle collisions at the LHC, magnetic monopoles
could stop in material surrounding the interaction points. Obsolete parts of
the beam pipe near the CMS interaction region, which were exposed to the
products of pp and heavy ion collisions, were analysed using a SQUID-based
magnetometer. The purpose of this work is to quantify the performance of the
magnetometer in the context of a monopole search using a small set of samples
of accelerator material ahead of the 2013 shutdown.Comment: 11 page
Stellar activity as noise in exoplanet detection I. Methods and application to solar-like stars and activity cycles
The detection of exoplanets using any method is prone to confusion due to the
intrinsic variability of the host star. We investigate the effect of cool
starspots on the detectability of the exoplanets around solar-like stars using
the radial velocity method. For investigating this activity-caused "jitter" we
calculate synthetic spectra using radiative transfer, known stellar atomic and
molecular lines, different surface spot configurations, and an added planetary
signal. Here, the methods are described in detail, tested and compared to
previously published studies. The methods are also applied to investigate the
activity jitter in old and young solar-like stars, and over a solar-like
activity cycles. We find that the mean full jitter amplitude obtained from the
spot surfaces mimicking the solar activity varies during the cycle
approximately between 1 m/s and 9 m/s. With a realistic observing frequency a
Neptune mass planet on a one year orbit can be reliably recovered. On the other
hand, the recovery of an Earth mass planet on a similar orbit is not feasible
with high significance. The methods developed in this study have a great
potential for doing statistical studies of planet detectability, and also for
investigating the effect of stellar activity on recovered planetary parameters.Comment: Accepted to MNRA
Form and width of spectral line of Josephson Flux-Flow oscillator
The behavior of a Josephson flux-flow oscillator in the presence of both bias
current and magnetic field fluctuations has been studied. To derive the
equation for slow phase dynamics in the limit of small noise intensity the
Poincare method has been used. Both the form of spectral line and the linewidth
of the flux-flow oscillator have been derived exactly on the basis of technique
presented in the book of Malakhov, known limiting cases are considered, limits
of their applicability are discussed and appearance of excess noise is
explained. Good coincidence of theoretical description with experimental
results has been demonstrated.Comment: 10 pages, 5 figure
Deep far infrared ISOPHOT survey in "Selected Area 57", I. Observations and source counts
We present here the results of a deep survey in a 0.4 sq.deg. blank field in
Selected Area 57 conducted with the ISOPHOT instrument aboard ESAs Infrared
Space Observatory (ISO) at both 60 um and 90 um. The resulting sky maps have a
spatial resolution of 15 x 23 sq.arcsec. per pixel which is much higher than
the 90 x 90 sq.arcsec. pixels of the IRAS All Sky Survey. We describe the main
instrumental effects encountered in our data, outline our data reduction and
analysis scheme and present astrometry and photometry of the detected point
sources. With a formal signal to noise ratio of 6.75 we have source detection
limits of 90 mJy at 60 um and 50 mJy at 90 um. To these limits we find
cumulated number densities of 5+-3.5 per sq.deg. at 60 um and 14.8+-5.0 per
sq.deg.at 90 um. These number densities of sources are found to be lower than
previously reported results from ISO but the data do not allow us to
discriminate between no-evolution scenarios and various evolutionary models.Comment: 15 pages, 11 figures, accepted by Astronomy & Astrophysic
Long Josephson junctions with spatially inhomogeneous driving
The phase dynamics of a long Josephson junction with spatially
inhomogeneously distributed bias current is considered for the case of a dense
soliton chain (regime of the Flux Flow oscillator). To derive the analytical
solution of the corresponding sine-Gordon equation the Poincare method has been
used. In the range of the validity of the theory good coincidence between
analytically derived and numerically computed current-voltage characteristics
have been demonstrated for the simplest example of unitstep function
distribution of bias current (unbiased tail). It is shown, that for the
considered example of bias current distribution, there is an optimal length of
unbiased tail that maximizes the amplitude of the main harmonic and minimizes
the dynamical resistance (thus leading to reduction of a linewidth).Comment: 7 pages, 5 figure
Migration routes of the Chestnut-mandibled Toucan
This is where the abstract of this record would appear. This is only demonstration data
Insect cells are superior to Escherichia coli in producing malaria proteins inducing IgG targeting PfEMP1 on infected erythrocytes
<p>Abstract</p> <p>Background</p> <p>The PFD1235w <it>Plasmodium falciparum </it>erythrocyte membrane protein 1 (PfEMP1) antigen is associated with severe malaria in children and can be expressed on the surface of infected erythrocytes (IE) adhering to ICAM1. However, the exact three-dimensional structure of this PfEMP1 and its surface-exposed epitopes are unknown. An insect cell and <it>Escherichia coli </it>based system was used to express single and double domains encoded by the <it>pfd1235w var </it>gene. The resulting recombinant proteins have been evaluated for yield and purity and their ability to induce rat antibodies, which react with the native PFD1235w PfEMP1 antigen expressed on 3D7<sub>PFD1235w</sub>-IE. Their recognition by human anti-malaria antibodies from previously infected Tanzanian donors was also analysed.</p> <p>Methods</p> <p>The recombinant proteins were run on SDS-PAGE and Western blots for quantification and size estimation. Insect cell and <it>E. coli</it>-produced recombinant proteins were coupled to a bead-based Luminex assay to measure the plasma antibody reactivity of 180 samples collected from Tanzanian individuals. The recombinant proteins used for immunization of rats and antisera were also tested by flow cytometry for their ability to surface label 3D7<sub>PFD1235w</sub>-IE.</p> <p>Results</p> <p>All seven pAcGP67A constructs were successfully expressed as recombinant protein in baculovirus-infected insect cells and subsequently produced to a purity of 60-97% and a yield of 2-15 mg/L. By comparison, only three of seven pET101/D-TOPO constructs expressed in the <it>E. coli </it>system could be produced at all with purity and yield ranging from 3-95% and 6-11 mg/L. All seven insect cell, but only two of the <it>E. coli </it>produced proteins induced antibodies reactive with native PFD1235w expressed on 3D7<sub>PFD1235w</sub>-IE. The recombinant proteins were recognized in an age- and transmission intensity-dependent manner by antibodies from 180 Tanzanian individuals in a bead-based Luminex assay.</p> <p>Conclusions</p> <p>The baculovirus based insect cell system was distinctly superior to the <it>E. coli </it>expression system in producing a larger number of different recombinant PFD1235w protein domains and these were significantly easier to purify at a useful yield. However, proteins produced in both systems were able to induce antibodies in rats, which can recognize the native PFD1235w on the surface of IE.</p
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