Debye mass and heavy quark potential in a PNJL quark plasma

We calculate the Debye mass for the screening of the heavy quark potential in a plasma of massless quarks coupled to the temporal gluon background governed by the Polyakov loop potential within the PNJL model in RPA approximation. We give a physical motivation for a recent phenomenological fit of lattice data by applying the calculated Debye mass with its suppression in the confined phase due to the Polyakov-loop to a description of the temperature dependence of the singlet free energy for QCD with a heavy quark pair at infinite separation. We compare the result to lattice data.Comment: 6 pages, 1 figure, contribution to Proceedings of the 6th International Conference on "Critical Point and Onset of Deconfinement", to appear in Phys. At. Nucl., vol. 7

Optoelectronic comb generation and cross-injection locking of photonic integrated circuit for millimetre-wave generation

We demonstrate how a monolithically integrated heterodyne source was used for a 33.6 GHz signal generation using an optical solution by a combination of cross-optical injection locking inside the chip and electrical injection locking at the RF signal 7th sub-harmonic

The enzymatic activity of the VEGFR2-receptor for the biosynthesis of dinucleoside polyphosphates

The group of dinucleoside polyphosphates encompasses a large number of molecules consisting of two nucleosides which are connected by a phosphate chain of variable length. While the receptors activated by dinucleoside polyphosphates as well as their degradation have been studied in detail, its biosynthesis has not been elucidated so far. Since endothelial cells released the dinucleoside polyphosphate uridine adenosine tetraphosphate (Up4A), we tested cytosolic proteins of human endothelial cells obtained from dermal vessels elicited for enzymatic activity. When incubated with ADP and UDP, these cells showed increasing concentrations of Up4A. The underlying enzyme was isolated by chromatography and the mass spectrometric analysis revealed that the enzymatic activity was caused by the vascular endothelial growth factor receptor 2 (VEGFR2). Since VEGFR2 but neither VEGFR1 nor VEGFR3 were capable to synthesise dinucleoside polyphosphates, Tyr-1175 of VEGFR2 is most likely essential for the enzymatic activity of interest. Further, VEGFR2-containing cells like HepG2, THP-1 and RAW264.7 were capable of synthesising dinucleoside polyphosphates. VEGFR2-transfected HEK 293T/17 but not native HEK 293T/17 cells synthesised dinucleoside polyphosphates in vivo too. The simultaneous biosynthesis of dinucleoside polyphosphates could amplify the response to VEGF, since dinucleoside polyphosphates induce cellular growth via P2Y purinergic receptors. Thus the biosynthesis of dinucleoside polyphosphates by VEGFR2 may enhance the proliferative response to VEGF. Given that VEGFR2 is primarily expressed in endothelial cells, the biosynthesis of dinucleoside polyphosphates is mainly located in the vascular system. Since the vasculature is also the main site of action of dinucleoside polyphosphates, activating vascular purinoceptors, blood vessels appear as an autocrine system with respect to dinucleoside polyphosphates. We conclude that VEGFR2 receptor is capable of synthesising dinucleoside polyphosphates. These mediators may modulate the effects of VEGFR2 due to their proliferative effects

The UTMOST pulsar timing programme I: overview and first results

We present an overview and the first results from a large-scale pulsar timing programme that is part of the UTMOST project at the refurbished Molonglo Observatory Synthesis Radio Telescope (MOST) near Canberra, Australia. We currently observe more than 400 mainly bright southern radio pulsars with up to daily cadences. For 205 (8 in binaries, 4 millisecond pulsars) we publish updated timing models, together with their flux densities, flux density variability, and pulse widths at 843 MHz, derived from observations spanning between 1.4 and 3 yr. In comparison with the ATNF pulsar catalogue, we improve the precision of the rotational and astrometric parameters for 123 pulsars, for 47 by at least an order of magnitude. The time spans between our measurements and those in the literature are up to 48 yr, which allows us to investigate their long-term spin-down history and to estimate proper motions for 60 pulsars, of which 24 are newly determined and most are major improvements. The results are consistent with interferometric measurements from the literature. A model with two Gaussian components centred at 139 and $463~\text{km} \: \text{s}^{-1}$ fits the transverse velocity distribution best. The pulse duty cycle distributions at 50 and 10 per cent maximum are best described by log-normal distributions with medians of 2.3 and 4.4 per cent, respectively. We discuss two pulsars that exhibit spin-down rate changes and drifting subpulses. Finally, we describe the autonomous observing system and the dynamic scheduler that has increased the observing efficiency by a factor of 2-3 in comparison with static scheduling.Comment: 31 pages, 14 figures, 6 tables, accepted for publication in MNRA

The first interferometric detections of Fast Radio Bursts

We present the first interferometric detections of Fast Radio Bursts (FRBs), an enigmatic new class of astrophysical transient. In a 180-day survey of the Southern sky we discovered 3 FRBs at 843 MHz with the UTMOST array, as part of commissioning science during a major ongoing upgrade. The wide field of view of UTMOST ($\approx 9$ deg$^{2}$) is well suited to FRB searches. The primary beam is covered by 352 partially overlapping fan-beams, each of which is searched for FRBs in real time with pulse widths in the range 0.655 to 42 ms, and dispersion measures $\leq$2000 pc cm$^{-3}$. Detections of FRBs with the UTMOST array places a lower limit on their distances of $\approx 10^4$ km (limit of the telescope near-field) supporting the case for an astronomical origin. Repeating FRBs at UTMOST or an FRB detected simultaneously with the Parkes radio telescope and UTMOST, would allow a few arcsec localisation, thereby providing an excellent means of identifying FRB host galaxies, if present. Up to 100 hours of follow-up for each FRB has been carried out with the UTMOST, with no repeating bursts seen. From the detected position, we present 3$\sigma$ error ellipses of 15 arcsec x 8.4 deg on the sky for the point of origin for the FRBs. We estimate an all-sky FRB rate at 843 MHz above a fluence $\cal F_\mathrm{lim}$ of 11 Jy ms of $\sim 78$ events sky$^{-1}$ d$^{-1}$ at the 95 percent confidence level. The measured rate of FRBs at 843 MHz is of order two times higher than we had expected, scaling from the FRB rate at the Parkes radio telescope, assuming that FRBs have a flat spectral index and a uniform distribution in Euclidean space. We examine how this can be explained by FRBs having a steeper spectral index and/or a flatter log$N$-log$\mathcal{F}$ distribution than expected for a Euclidean Universe.Comment: 13 pages, 8 figures, 2 table

An overview on extremity dosimetry in medical applications

Some activities of EURADOS Working Group 9 (WG9) are presently funded by the European Commission (CONRAD project). The objective of WG9 is to promote and co-ordinate research activities for the assessment of occupational exposures to staff at workplaces in interventional radiology (IR) and nuclear medicine. For some of these applications, the skin of the fingers is the limiting organ for individual monitoring of external radiation. Therefore, sub-group 1 of WG9 deals with the use of extremity dosemeters in medical radiation fields. The wide variety of radiation field characteristics present in a medical environment together with the difficulties in measuring a local dose that is representative for the maximum skin dose, usually with one single detector, makes it difficult to perform accurate extremity dosimetry. Sub-group 1 worked out a thorough literature review on extremity dosimetry issues in diagnostic and therapeutic nuclear medicine and positron emission tomography, interventional radiology and interventional cardiology and brachytherapy. Some studies showed that the annual dose limits could be exceeded if the required protection measures are not taken, especially in nuclear medicine. The continuous progress in new applications and techniques requires an important effort in radiation protection and trainin

An overview of the use of extremity dosemeters in some European countries for medical applications

Some medical applications are associated with high doses to the extremities of the staff exposed to ionising radiation. At workplaces in nuclear medicine, interventional radiology, interventional cardiology and brachytherapy, extremities can be the limiting organs as far as regulatory dose limits for workers are concerned. However, although the need for routine extremity monitoring is clear for these applications, no data about the status of routine extremity monitoring reported by different countries was collected and analysed so far, at least at a European level. In this article, data collected from seven European countries are presented. They are compared with extremity doses extracted from dedicated studies published in the literature which were reviewed in a previous publication. The analysis shows that dedicated studies lead to extremity doses significantly higher than the reported doses, suggesting that either the most exposed workers are not monitored, or the dosemeters are not routinely worn or not worn at appropriate position

Comparison of Branching Ratio and Sum-Rule Analyses of Magnetic Circular Dichroism in X-Ray-Absorption Spectroscopy

Two localized picture methods of analyzing the magnetic circular dichroism in x-ray absorption will be applied to experimental results: the branching ratio (BR) and sum rule (SR) approaches. A derivation of the BR formulas and detailed comparison to the SR expressions will be made, including error estimations. The BR approach will be seen to be a limiting case form of the SR spin-moment expression and provide a simple picture of the underlying physics in magnetic x-ray circular dichroism absorption in 3d magnetic materials