48 research outputs found

    Gauge conditions for binary black hole puncture data based on an approximate helical Killing vector

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    We show that puncture data for quasicircular binary black hole orbits allow a special gauge choice that realizes some of the necessary conditions for the existence of an approximate helical Killing vector field. Introducing free parameters for the lapse at the punctures we can satisfy the condition that the Komar and ADM mass agree at spatial infinity. Several other conditions for an approximate Killing vector are then automatically satisfied, and the 3-metric evolves on a timescale smaller than the orbital timescale. The time derivative of the extrinsic curvature however remains significant. Nevertheless, quasicircular puncture data are not as far from possessing a helical Killing vector as one might have expected.Comment: 11 pages, 6 figures, 2 table

    Specification of ACMG/AMP guidelines for standardized variant interpretation in familial hypercholesterolemia: On behalf of the ClinGen FH Variant Curation Expert Panel

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    Familial Hypercholesterolemia (FH): Lipid metabolism autosomal dominant condition; Patients present elevated low-density lipoprotein cholesterol (LDL-C) and total cholesterol (TC) values since childhood → increased risk of atherosclerotic cardiovascular disease; High heterozygote prevalence (1/250); Homozygous rare (1/1 000 000); Caused by pathogenic variants in LDLR (>90%), APOB (5-10%) and PCSK9 (1-3%) genes.N/

    Discourse and the Projection of Corporate Culture: The Mission Statement

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    This article explores how corporations project their corporate philosophy through `Mission Statements'. Linguistic and textual analysis of such statements drawn from a sizeable corpus allows us to typify the texts as constituting a non-routine, organizational genre, and one that has recently become of some significance. This discussion serves as a foundation for a contextual and intertextual analysis (cf. Fairclough, 1992) of Mission Statements from two well-known US companies. By detailing the history, rationale and role of these Mission Statements we indicate how the texts are rhetorically designed in order to ensure maximum employee `buy-in'. Despite linguistic and rhetorical similarities among the texts, an exploration of context reveals startling differences in communicative purpose. In one case the Mission Statement emerges as an empowering historical vision to be protected and nurtured through all vicissitudes; in the other case, the rewriting of the Mission Statement emerges as a collaborative response to crisis. The article ends by discussing the implications of such findings for contemporary approaches to discourse and genre analysis within institutional linguistics.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/67339/2/10.1177_0957926595006002005.pd
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