NEOTROPICAL XENARTHRANS: a data set of occurrence of xenarthran species in the Neotropics

Xenarthrans – anteaters, sloths, and armadillos – have essential functions for ecosystem maintenance, such as insect control and nutrient cycling, playing key roles as ecosystem engineers. Because of habitat loss and fragmentation, hunting pressure, and conflicts with 24 domestic dogs, these species have been threatened locally, regionally, or even across their full distribution ranges. The Neotropics harbor 21 species of armadillos, ten anteaters, and six sloths. Our dataset includes the families Chlamyphoridae (13), Dasypodidae (7), Myrmecophagidae (3), Bradypodidae (4), and Megalonychidae (2). We have no occurrence data on Dasypus pilosus (Dasypodidae). Regarding Cyclopedidae, until recently, only one species was recognized, but new genetic studies have revealed that the group is represented by seven species. In this data-paper, we compiled a total of 42,528 records of 31 species, represented by occurrence and quantitative data, totaling 24,847 unique georeferenced records. The geographic range is from the south of the USA, Mexico, and Caribbean countries at the northern portion of the Neotropics, to its austral distribution in Argentina, Paraguay, Chile, and Uruguay. Regarding anteaters, Myrmecophaga tridactyla has the most records (n=5,941), and Cyclopes sp. has the fewest (n=240). The armadillo species with the most data is Dasypus novemcinctus (n=11,588), and the least recorded for Calyptophractus retusus (n=33). With regards to sloth species, Bradypus variegatus has the most records (n=962), and Bradypus pygmaeus has the fewest (n=12). Our main objective with Neotropical Xenarthrans is to make occurrence and quantitative data available to facilitate more ecological research, particularly if we integrate the xenarthran data with other datasets of Neotropical Series which will become available very soon (i.e. Neotropical Carnivores, Neotropical Invasive Mammals, and Neotropical Hunters and Dogs). Therefore, studies on trophic cascades, hunting pressure, habitat loss, fragmentation effects, species invasion, and climate change effects will be possible with the Neotropical Xenarthrans dataset

Risk profiles and one-year outcomes of patients with newly diagnosed atrial fibrillation in India: Insights from the GARFIELD-AF Registry.

BACKGROUND: The Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF) is an ongoing prospective noninterventional registry, which is providing important information on the baseline characteristics, treatment patterns, and 1-year outcomes in patients with newly diagnosed non-valvular atrial fibrillation (NVAF). This report describes data from Indian patients recruited in this registry. METHODS AND RESULTS: A total of 52,014 patients with newly diagnosed AF were enrolled globally; of these, 1388 patients were recruited from 26 sites within India (2012-2016). In India, the mean age was 65.8 years at diagnosis of NVAF. Hypertension was the most prevalent risk factor for AF, present in 68.5% of patients from India and in 76.3% of patients globally (P < 0.001). Diabetes and coronary artery disease (CAD) were prevalent in 36.2% and 28.1% of patients as compared with global prevalence of 22.2% and 21.6%, respectively (P < 0.001 for both). Antiplatelet therapy was the most common antithrombotic treatment in India. With increasing stroke risk, however, patients were more likely to receive oral anticoagulant therapy [mainly vitamin K antagonist (VKA)], but average international normalized ratio (INR) was lower among Indian patients [median INR value 1.6 (interquartile range {IQR}: 1.3-2.3) versus 2.3 (IQR 1.8-2.8) (P < 0.001)]. Compared with other countries, patients from India had markedly higher rates of all-cause mortality [7.68 per 100 person-years (95% confidence interval 6.32-9.35) vs 4.34 (4.16-4.53), P < 0.0001], while rates of stroke/systemic embolism and major bleeding were lower after 1 year of follow-up. CONCLUSION: Compared to previously published registries from India, the GARFIELD-AF registry describes clinical profiles and outcomes in Indian patients with AF of a different etiology. The registry data show that compared to the rest of the world, Indian AF patients are younger in age and have more diabetes and CAD. Patients with a higher stroke risk are more likely to receive anticoagulation therapy with VKA but are underdosed compared with the global average in the GARFIELD-AF. CLINICAL TRIAL REGISTRATION-URL: http://www.clinicaltrials.gov. Unique identifier: NCT01090362

Selectivity of Chlorimuron-Ethyl to Castorbean Crops.

Castorbean presents high sensitivity to competition; therefore, it is necessary to develop alternatives for the weed management, mainly for the chemical control of eudicotyledons species. The goal of this work was to evaluate the selectivity of chlorimuron-ethyl to castorbean crops in different development stages. Four experiments differentiated by the genetic material were conducted: Lyra, Íris and Savana hybrids and AL Guarany 2002 cultivar. The treatments corresponded to the application conditions of chlorimuron-ethyl [sample control with no application, doses of 15 e 20 g a.i. ha-1 with the formulations Classic? and Clorimuron Master Nortox?] in two phenological crop stages (4 to 5 and 7 to 8 true leaf stages). The experimental design was in randomized blocks with four replications, in a factorial scheme of 5 x 2 (herbicide and application stage). The intoxication was more severe for the 7 to 8 leaf stage and with the dose of 20 g ha-1 on day 7 days after application (DAA); there were plant recovery and mild symptoms on day 21 DAA, especially for the 4 to 5 leaf stage. The yield was reduced with the 20 g ha-1 dose for Lyra hybrid with both formulations and for Savana castorbean, only with the Classic? formulation. The chlorimuron-ethyl herbicide, at 15 g ha-1, showed selectivity to castorbean, regardless of the stage application (4 to 5 or 7 to 8 leaves).Made available in DSpace on 2017-12-23T23:18:35Z (GMT). No. of bitstreams: 1 Selectivityof....pdf: 3172976 bytes, checksum: f205c85d0dae95bf20f0435f9b468a4b (MD5) Previous issue date: 2017-12-21bitstream/item/169616/1/Selectivity-of-....pdfPublicação online

Selectivity of Chlorimuron-Ethyl to Castorbean Crops

<div><p>ABSTRACT: Castorbean presents high sensitivity to competition; therefore, it is necessary to develop alternatives for the weed management, mainly for the chemical control of eudicotyledons species. The goal of this work was to evaluate the selectivity of chlorimuron-ethyl to castorbean crops in different development stages. Four experiments differentiated by the genetic material were conducted: Lyra, Íris and Savana hybrids and AL Guarany 2002 cultivar. The treatments corresponded to the application conditions of chlorimuron-ethyl [sample control with no application, doses of 15 e 20 g a.i. ha-1 with the formulations Classic™ and Clorimuron Master Nortox™] in two phenological crop stages (4 to 5 and 7 to 8 true leaf stages). The experimental design was in randomized blocks with four replications, in a factorial scheme of 5 x 2 (herbicide and application stage). The intoxication was more severe for the 7 to 8 leaf stage and with the dose of 20 g ha-1 on day 7 days after application (DAA); there were plant recovery and mild symptoms on day 21 DAA, especially for the 4 to 5 leaf stage. The yield was reduced with the 20 g ha-1 dose for Lyra hybrid with both formulations and for Savana castorbean, only with the Classic™ formulation. The chlorimuron-ethyl herbicide, at 15 g ha-1, showed selectivity to castorbean, regardless of the stage application (4 to 5 or 7 to 8 leaves).</p></div

Identificação imuno-histoquímica de VEGF e IGF-1 em ovários de cadelas no anestro e estro

Com o objetivo de verificar a presença de VEGF e IGF-1 nos ovários de cadelas, foram realizadas análises imuno-histoquímicas do estroma cortical; teca e granulosa de folículos secundários, terciários e terciários pré-ovulatórios luteinizados; e ovócitos de folículos primários, secundários e terciários de ovários de cinco cadelas em anestro (Anest) e cinco em estro (Est). A identificação das fases do ciclo estral foi realizada por citologia vaginal associada a dosagem plasmática de progesterona. Os ovários foram submetidos a tratamento imuno-histoquímico para identificação de VEGF (anticorpo primário PU 360-UP, Biogenex, USA; diluição 1:30) e IGF-1 (anticorpo primário PabCa, Gro-Pep, Austrália; diluição 1:100). Determinou-se um índice de imunomarcação (IM), para cada tecido avaliado, pela razão entre a área positivamente marcada dividida pela área total analisada. Para os ovócitos, verificou-se imunomarcação positiva ou negativa. As comparações de IM entre tecidos foram realizadas pelo teste de Wilcoxon (diferentes tecidos em mesmo grupo) ou Mann-Whitney (mesmo tecido entre diferentes grupos), todas no nível de 5% de significância. VEGF e IGF-1 foram identificados, de forma semelhante (P>0,05), em todas as estruturas avaliadas em ambos os grupos experimentais. Conclui-se que esses fatores de crescimento estão presentes em cadelas no anestro e estro, no estroma cortical ovariano, folículos em diferentes estádios de desenvolvimento e ovócitos