1,320 research outputs found
Resource-based View in Information Systems Research: A Meta-Analysis
Resource-based view is the theory that has been applied to analyze the impact of informa-tion technology on business performance. Its main argument is that competitive advan-tages are determined by the unique valuable resources controlled by an organization. IT as a valuable asset will have positive effect on firm performance. However, previous re-search on the issue is inconsistent. This paper reports a meta analysis of 42 papers pub-lished in major journals in information systems. Our findings indicate that the capability mediated model is better than the direct effect model and the major impact of IT is on ef-ficiency indicators
Loss of LR11/SORLA enhances early pathology in a mouse model of amyloidosis: Evidence for a proximal role in Alzheimer's disease
Alzheimer's disease (AD) is the most prevalent form of dementia, resulting in progressive neuronal death and debilitating damage to brain loci that mediate memory and higher cognitive function. While pathogenic genetic mutations have been implicated in approximately 2% of AD cases, the proximal events that underlie the common, sporadic form of the disease are incompletely understood. Converging lines of evidence from human neuropathology, basic biology, and genetics have implicated loss of the multifunctional receptor LR11 (also known as SORLA and SORL1) in AD pathogenesis. Cell-based studies suggest that LR11 reduces the formation of beta-amyloid (Abeta), the molecule believed to be a primary toxic species in AD. Recently, mutant mice deficient in LR11 were shown to upregulate murine Abeta in mouse brain. In the current study, LR11-deficient mice were crossed with transgenic mice expressing autosomal-dominant human AD genes, presenilin-1 (PS1DeltaE9) and amyloid precursor protein (APPswe). Here, we show that LR11 deficiency in this AD mouse model significantly increases Abeta levels and exacerbates early amyloid pathology in brain, causing a forward shift in disease onset that is LR11 gene dose-dependent. Loss of LR11 increases the processing of the APP holo-molecule into alpha-, beta-, and gamma-secretase derived metabolites. We propose that LR11 regulates APP processing and Abeta accumulation in vivo and is of proximal importance to the cascade of pathological amyloidosis. The results of the current study support the hypothesis that control of LR11 expression may exert critical effects on Alzheimer's disease susceptibility in humans
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Population transfer to high angular momentum states in infrared-assisted XUV photoionization of helium
An extreme-ultraviolet (XUV) laser pulse consisting of harmonics of a fundamental near-infrared (NIR) laser frequency is combined with the NIR pulse to systematically study two-color photoionization of helium atoms. A time-resolved photoelectron spectroscopy experiment is carried out where energy- A nd angle-resolved photoelectron distributions are obtained as a function of the NIR intensity and wavelength. Time-dependent Schrödinger equation calculations are performed for the conditions corresponding to the experiment and used to extract residual populations of Rydberg states resulting from excitation by the XUV + NIR pulse pair. The residual populations are studied as a function of the NIR intensity (3.5 × 1010-8 × 1012 W cm-2) and wavelength (760-820 nm). The evolution of the photoelectron distribution and the residual populations are interpreted using an effective restricted basis model, which includes the minimum set of states relevant to the features observed in the experiments. As a result, a comprehensive and intuitive picture of the laser-induced dynamics in helium atoms exposed to a two-color XUV-NIR light field is obtained. © 2020 The Author(s). Published by IOP Publishing Ltd
Hawking Radiation of Black Holes in Infrared Modified Ho\v{r}ava-Lifshitz Gravity
We study the Hawking radiation of the spherically symmetric, asymptotically
flat black holes in the infrared modified Horava-Lifshitz gravity by applying
the methods of covariant anomaly cancellation and effective action, as well as
the approach of Damour-Ruffini-Sannan's. These black holes behave as the usual
Schwarzschild ones of the general relativity when the radial distance is very
large. We also extend the method of covariant anomaly cancellation to derive
the Hawking temperature of the spherically symmetric, asymptotically AdS black
holes that represent the analogues of the Schwarzschild AdS ones.Comment: no figures, 16 pages,accepted by EPJ
Hydrodynamic theory for granular gases
A granular gas subjected to a permanent injection of energy is described by
means of hydrodynamic equations derived from a moment expansion method. The
method uses as reference function not a Maxwellian distribution but
a distribution , such that adds a fourth cumulant
to the velocity distribution. The formalism is applied to a stationary
conductive case showing that the theory fits extraordinarily well the results
coming from our molecular dynamic simulations once we determine as a
function of the inelasticity of the particle-particle collisions. The shape of
is independent of the size of the system.Comment: 10 pages, 9 figures, more about our research in
http://www.cec.uchile.cl/cinetica
Argon plasma treatment techniques on steel and effects on diamond-like carbon structure and delamination
Copyright © 2011 Elsevier B.V. All rights reserved.We demonstrate alteration in diamond-like carbon (DLC) film structure, chemistry and adhesion on steel, related to variation in the argon plasma pretreatment stage of plasma enhanced chemical vapour deposition. We relate these changes to the alteration in substrate structure, crystallinity and chemistry due to application of an argon plasma process with negative self bias up to 600 V. Adhesion of the DLC film to the substrate was assessed by examination of the spallated fraction of the film following controlled deformation. Films with no pretreatment step immediately delaminated. At 300 V pretreatment, the spallated fraction is 8.2%, reducing to 1.2% at 450 V and 0.02% at 600V. For bias voltages below 450V the adhesion enhancement is explained by a reduction in carbon contamination on the substrate surface, from 59at.% with no treatment to 26at.% at 450V, concurrently with a decrease in the surface roughness, Rq, from 31.5nm to 18.9nm. With a pretreatment bias voltage of 600V a nanocrystalline, nanostructured surface is formed, related to removal of chromium and relaxation of stress; X-ray diffraction indicates this phase is incipient at 450V. In addition to improving film adhesion, the nanotexturing of the substrate prior to film deposition results in a DLC film that shows an increase in sp3/sp2 ratio from 1.2 to 1.5, a reduction in surface roughness from 31nm to 21nm, and DLC nodular asperities with reduced diameter and increased uniformity of size and arrangement. These findings are consistent with the substrate alterations due to the plasma pretreatment resulting in limitation of surface diffusion in the growth process. This suggests that in addition to deposition phase processes, the parameters of the pretreatment process need to be considered when designing diamond-like carbon coatings.This work is partially supported by the Technology Strategy Board, reference BD266E
Covariant anomaly and Hawking radiation from the modified black hole in the rainbow gravity theory
Recently, Banerjee and Kulkarni (R. Banerjee, S. Kulkarni, arXiv:0707.2449
[hep-th]) suggested that it is conceptually clean and economical to use only
the covariant anomaly to derive Hawking radiation from a black hole. Based upon
this simplified formalism, we apply the covariant anomaly cancellation method
to investigate Hawking radiation from a modified Schwarzschild black hole in
the theory of rainbow gravity. Hawking temperature of the gravity's rainbow
black hole is derived from the energy-momentum flux by requiring it to cancel
the covariant gravitational anomaly at the horizon. We stress that this
temperature is exactly the same as that calculated by the method of cancelling
the consistent anomaly.Comment: 5 page
Anomaly analysis of Hawking radiation from Kaluza-Klein black hole with squashed horizon
Considering gravitational and gauge anomalies at the horizon, a new method
that to derive Hawking radiations from black holes has been developed by
Wilczek et al. In this paper, we apply this method to non-rotating and rotating
Kaluza-Klein black holes with squashed horizon, respectively. For the rotating
case, we found that, after the dimensional reduction, an effective U(1) gauge
field is generated by an angular isometry. The results show that the gauge
current and energy-momentum tensor fluxes are exactly equivalent to Hawking
radiation from the event horizon.Comment: 15 pages, no figures, the improved version, accepted by Eur. Phys. J.
Reduction and evaluation of two-loop graphs with arbitrary masses
We describe a general analytic-numerical reduction scheme for evaluating any
2-loop diagrams with general kinematics and general renormalizable
interactions, whereby ten special functions form a complete set after tensor
reduction. We discuss the symmetrical analytic structure of these special
functions in their integral representation, which allows for optimized
numerical integration. The process Z -> bb is used for illustration, for which
we evaluate all the 3-point, non-factorizable g^2*alpha_s mixed electroweak-QCD
graphs, which depend on the top quark mass. The isolation of infrared
singularities is detailed, and numerical results are given for all two-loop
three-point graphs involved in this process
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