Depolarization-activated potentiation of the T fiber synapse in the blue crab

The blue crab T fiber synapse, associated with the stretch receptor of the swimming leg, has a nonspiking presynaptic element that mediates tonic transmission. This synapse was isolated and a voltage clamp circuit was used to control the membrane potential at the release sites. The dependence of transmitter release on extracellular calcium, [Ca]o, was studied over a range of 2.5-40 mM. A power relationship of 2.7 was obtained between excitatory postsynaptic potential (EPSP) rate of rise and [Ca]o. Brief presynaptic depolarizing steps, 5-10 ms, presented at 0.5 Hz activated EPSP's of constant amplitude. Inserting a 300-ms pulse (conditioning pulse) between these test pulses potentiated the subsequent test EPSPs. This depolarization-activated potentiation (DAP) lasted for 10-20 s and decayed with a single exponential time course. The decay time course remained invariant with test pulse frequencies ranging from 0.11 to 1.1 Hz. The magnitude and decay time course of DAP were independent of the test pulse amplitudes. The magnitude of DAP was a function of conditioning pulse amplitudes. Large conditioning pulses activated large potentiations, whereas the decay time constants were not changed. The DAP is a Ca-dependent process. When the amplitude of conditioning pulses approached the Ca equilibrium potential, the magnitude of potentiation decreased. Repeated application of conditioning pulses, at 2-s intervals, did not produce additional potentiation beyond the level activated by the first conditioning pulse. Comparison of the conditioning EPSP waveforms activated repetitively indicated that potentiation lasted transiently, 100 ms, during a prolonged release. Possible mechanisms of the potentiation are discussed in light of these new findings.The blue crab T fiber synapse, associated with the stretch receptor of the swimming leg, has a nonspiking presynaptic element that mediates tonic transmission. This synapse was isolated and a voltage clamp circuit was used to control the membrane potential at the release sites. The dependence of transmitter release on extracellular calcium, [Ca]o, was studied over a range of 2.5-40 mM. A power relationship of 2.7 was obtained between excitatory postsynaptic potential (EPSP) rate of rise and [Ca]o. Brief presynaptic depolarizing steps, 5-10 ms, presented at 0.5 Hz activated EPSP's of constant amplitude. Inserting a 300-ms pulse (conditioning pulse) between these test pulses potentiated the subsequent test EPSPs. This depolarization-activated potentiation (DAP) lasted for 10-20 s and decayed with a single exponential time course. The decay time course remained invariant with test pulse frequencies ranging from 0.11 to 1.1 Hz. The magnitude and decay time course of DAP were independent of the test pulse amplitudes. The magnitude of DAP was a function of conditioning pulse amplitudes. Large conditioning pulses activated large potentiations, whereas the decay time constants were not changed. The DAP is a Ca-dependent process. When the amplitude of conditioning pulses approached the Ca equilibrium potential, the magnitude of potentiation decreased. Repeated application of conditioning pulses, at 2-s intervals, did not produce additional potentiation beyond the level activated by the first conditioning pulse. Comparison of the conditioning EPSP waveforms activated repetitively indicated that potentiation lasted transiently, 100 ms, during a prolonged release. Possible mechanisms of the potentiation are discussed in light of these new findings.NS-07942 - NINDS NIH HHS; NS-13742 - NINDS NIH HH

Numerical solutions of 2-D multi-stage rotor/stator unsteady flow interactions

The Rai method of single-stage rotor/stator flow interaction is extended to handle multistage configurations. In this study, a two-dimensional Navier-Stokes multi-zone approach was used to investigate unsteady flow interactions within two multistage axial turbines. The governing equations are solved by an iterative, factored, implicit finite-difference, upwind algorithm. Numerical accuracy is checked by investigating the effect of time step size, the effect of subiteration in the Newton-Raphson technique, and the effect of full viscous versus thin-layer approximation. Computer results compared well with experimental data. Unsteady flow interactions, wake cutting, and the associated evolution of vortical entities are discussed

Tip vortex computer code SRATIP. User's guide

This User's Guide applies to the three dimensional viscous flow forward marching analysis, PEPSIG, as used for the calculation of the helicopter tip vortex flow field. The guide presents a discussion of the program flow and subroutines, as well as a list of sample input and output

Core-collapse supernovae ages and metallicities from emission-line diagnostics of nearby stellar populations

Massive stars are the main objects that illuminate H II regions and they evolve quickly to end their lives in core-collapse supernovae (CCSNe). Thus it is important to investigate the association between CCSNe and H II regions. In this paper, we present emission line diagnostics of the stellar populations around nearby CCSNe, that include their host H II regions, from the PMAS/PPAK Integral-field Supernova hosts COmpilation (PISCO). We then use BPASS stellar population models to determine the age, metallicity and gas parameters for H II regions associated with CCSNe, contrasting models that consider either single star evolution alone or incorporate interacting binaries. We find binary-star models, that allow for ionizing photon loss, provide a more realistic fit to the observed CCSN hosts with metallicities that are closer to those derived from the oxygen abundance in O3N2. We also find that type II and type Ibc SNe arise from progenitor stars of similar age, mostly from 7 to 45 Myr, which corresponds to stars with masses < 20 solar mass . However these two types SNe have little preference in their host environment metallicity measured by oxygen abundance or in progenitor initial mass. We note however that at lower metallicities supernovae are more likely to be of type II.Comment: 22 pages, 19 Figures, 6 Tables. Accepted by MNRAS. Comments welcom

Lifshitz Transition in Underdoped Cuprates

Recent studies show that quantum oscillations thought to be associated with a density wave reconstructed Fermi surface disappear at a critical value of the doping for YBa2Cu3O6+y, and the cyclotron mass diverges as the critical value is approached from the high doping side. We argue that the phenomenon is due to a Lifshitz transition where the pockets giving rise to the quantum oscillations connect to form an open (quasi-1d) Fermi surface. The estimated critical doping is close to that found by experiment, and the theory predicts a logarithmic divergence of the cyclotron mass with a coefficient comparable to that observed in experiment.Comment: 4 pages, 4 figure

Direct Numerical Simulation of a separated channel flow with a smooth profile

A direct numerical simulation (DNS) of a channel flow with one curved surface was performed at moderate Reynolds number (Re_tau = 395 at the inlet). The adverse pressure gradient was obtained by a wall curvature through a mathematical mapping from physical coordinates to Cartesian ones. The code, using spectral spanwise and normal discretization, combines the advantage of a good accuracy with a fast integration procedure compared to standard numerical procedures for complex geometries. The turbulent flow slightly separates on the profile at the lower curved wall and is at the onset of separation at the opposite flat wall. The thin separation bubble is characterized with a reversal flow fraction. Intense vortices are generated near the separation line on the lower wall but also at the upper wall. Turbulent normal stresses and kinetic energy budget are investigated along the channel.Comment: 23 pages, submitted to Journal of Turbulenc

Improvement of black nickel coatings

Selectively absorbing black nickel coatings are among the most optically efficient low cost coatings for use on flat plate solar collectors. However, a current Ni-Zn-S-O coating in use is quite susceptible to a humid environment, degrading badly in less than ten days at 38 C (100 F) at 95 percent relative humidity. Therefore, a black nickel formula was developed which can withstand such exposures with no loss of optical efficiency, solar absorption of 0.92 and an infrared emittance (at 100 C) of 1.00 were still present after 14 days of humidity exposure. This compares to a solar absorptance of only 0.72 for the previous formula after a similar time period. The electroplating bath and conditions were changed to obtain the more stable coating configuration. The effect of bath composition, temperature, pH, and plating current density and time on the coating composition, spectral optical properties and durability were investigated systematically

Toroidal transformers procedure 902.66-01 Final report

Qualification tests of multi-secondary toroidal transformers and open-construction ratio toroidal transformer