20,532 research outputs found
Characteristic Energy of the Coulomb Interactions and the Pileup of States
Tunneling data on crystals confirm
Coulomb interaction effects through the dependence of the
density of states. Importantly, the data and analysis at high energy, E, show a
pileup of states: most of the states removed from near the Fermi level are
found between ~40 and 130 meV, from which we infer the possibility of universal
behavior. The agreement of our tunneling data with recent photoemission results
further confirms our analysis.Comment: 4 pages, 4 figures, submitted to PR
Mental States Are Like Diseases
While Quine’s linguistic behaviorism is well-known, his Kant Lectures contain one of his most detailed discussions of behaviorism in psychology and the philosophy of mind. Quine clarifies the nature of his psychological commitments by arguing for a modest view that is against ‘excessively restrictive’ variants of behaviorism while maintaining ‘a good measure of behaviorist discipline…to keep [our mental] terms under control’. In this paper, I use Quine’s Kant Lectures to reconstruct his position. I distinguish three types of behaviorism in psychology and the philosophy of mind: ontological behaviorism, logical behaviorism, and epistemological behaviorism. I then consider Quine’s perspective on each of these views and argue that he does not fully accept any of them. By combining these perspectives we arrive at Quine’s surprisingly subtle view about behaviorism in psychology
Mangiferin: A Promising Anticancer Bioactive
Of late, several biologically active antioxidants from natural products have been investigated by the researchers in order to combat the root cause of carcinogenesis, i.e., oxidative stress. Mangiferin, a therapeutically active C-glucosylated xanthone, is extracted from pulp, peel, seed, bark and leaf of Mangifera indica. These polyphenols of mangiferin exhibit antioxidant properties and tend to decrease the oxygen-free radicals, thereby reducing the DNA damage. Indeed, its capability to modulate several key inflammatory pathways undoubtedly helps in stalling the progression of carcinogenesis. The current review article emphasizes an updated account on the patents published on the chemopreventive action of Mangiferin, apoptosis induction made on various cancer cells, along with proposed antioxidative activities and patent mapping of other important therapeutic properties. Considering it as promising polyphenol, this paper would also summarize the diverse molecular targets of Mangiferin
"Boring formal methods" or "Sherlock Holmes deduction methods"?
This paper provides an overview of common challenges in teaching of logic and
formal methods to Computer Science and IT students. We discuss our experiences
from the course IN3050: Applied Logic in Engineering, introduced as a "logic
for everybody" elective course at at TU Munich, Germany, to engage pupils
studying Computer Science, IT and engineering subjects on Bachelor and Master
levels. Our goal was to overcome the bias that logic and formal methods are not
only very complicated but also very boring to study and to apply. In this
paper, we present the core structure of the course, provide examples of
exercises and evaluate the course based on the students' surveys.Comment: Preprint. Accepted to the Software Technologies: Applications and
Foundations (STAF 2016). Final version published by Springer International
Publishing AG. arXiv admin note: substantial text overlap with
arXiv:1602.0517
Dilaton Quantum Cosmology with a Schrodinger-like equation
A quantum cosmological model with radiation and a dilaton scalar field is
analysed. The Wheeler-deWitt equation in the mini-superspace induces a
Schr\"odinger equation, which can be solved. An explicit wavepacket is
constructed for a particular choice of the ordering factor. A consistent
solution is possible only when the scalar field is a phantom field. Moreover,
although the wavepacket is time dependent, a Bohmian analysis allows to extract
a bouncing behaviour for the scale factor.Comment: 14 pages, 3 figures in eps format. Minors corrections, new figure
The Ontology of Intentional Agency in Light of Neurobiological Determinism: Philosophy Meets Folk Psychology
The moot point of the Western philosophical rhetoric about free will
consists in examining whether the claim of authorship to intentional, deliberative
actions fits into or is undermined by a one-way causal framework of determinism.
Philosophers who think that reconciliation between the two is possible are known as
metaphysical compatibilists. However, there are philosophers populating the other
end of the spectrum, known as the metaphysical libertarians, who maintain that claim
to intentional agency cannot be sustained unless it is assumed that indeterministic
causal processes pervade the action-implementation apparatus employed by the agent.
The metaphysical libertarians differ among themselves on the question of whether the
indeterministic causal relation exists between the series of intentional states and
processes, both conscious and unconscious, and the action, making claim for what has
come to be known as the event-causal view, or between the agent and the action,
arguing that a sort of agent causation is at work. In this paper, I have tried to propose
that certain features of both event-causal and agent-causal libertarian views need to be
combined in order to provide a more defendable compatibilist account accommodating
deliberative actions with deterministic causation. The ‘‘agent-executed-eventcausal
libertarianism’’, the account of agency I have tried to develop here, integrates
certain plausible features of the two competing accounts of libertarianism turning
them into a consistent whole. I hope to show in the process that the integration of these
two variants of libertarianism does not challenge what some accounts of metaphysical
compatibilism propose—that there exists a broader deterministic relation between the
web of mental and extra-mental components constituting the agent’s dispositional
system—the agent’s beliefs, desires, short-term and long-term goals based on them,
the acquired social, cultural and religious beliefs, the general and immediate and
situational environment in which the agent is placed, etc. on the one hand and the
decisions she makes over her lifetime on the basis of these factors. While in the
‘‘Introduction’’ the philosophically assumed anomaly between deterministic causation
and the intentional act of deciding has been briefly surveyed, the second section is
devoted to the task of bridging the gap between compatibilism and libertarianism. The
next section of the paper turns to an analysis of folk-psychological concepts and
intuitions about the effects of neurochemical processes and prior mental events on the
freedom of making choices. How philosophical insights can be beneficially informed
by taking into consideration folk-psychological intuitions has also been discussed,
thus setting up the background for such analysis. It has been suggested in the end that
support for the proposed theory of intentional agency can be found in the folk-psychological intuitions, when they are taken in the right perspective
An E-mail Service in a Military Adolescent Medicine Clinic: will teens use it and what for?
The goal of this study was to determine utilization patterns of an Adolescent Medicine Clinic e-mail service. An e-mail service was offered to 6134 patients presenting for care to a military Adolescent Medicine Clinic in San Antonio, Texas over a 6-month period. Families had to complete an authorization form acknowledging that the e-mail service was not encrypted and was not to be used for emergent issues prior to use. 482 families signed up for the service. A total of 42 e-mails were received from 28 of these families. 75% of all e-mails were initiated by parents. The majority of e-mails were administrative issues including: medication refills, lab follow up, and referrals requests. In conclusion, the e-mail service was a low cost method to increase communication options for our patients that was not associated with a large increase in clinic workload because of low utilization rates, especially among younger adolescents.Keywords: Adolescents; E-mail; Internet; Electronic communication; Physicianpatient communicatio
Attempts to detect retrotransposition and de novo deletion of Alus and other dispersed repeats at specific loci in the human genome
Dispersed repeat elements contribute to genome instability by de novo insertion and unequal recombination between repeats. To study the dynamics of these processes, we have developed single DNA molecule approaches to detect de novo insertions at a single locus and Alu-mediated deletions at two different loci in human genomic DNA. Validation experiments showed these approaches could detect insertions and deletions at frequencies below 10(-6) per cell. However, bulk analysis of germline (sperm) and somatic DNA showed no evidence for genuine mutant molecules, placing an upper limit of insertion and deletion rates of 2 x 10(-7) and 3 x 10(-7), respectively, in the individuals tested. Such re-arrangements at these loci therefore occur at a rate lower than that detectable by the most sensitive methods currently available
Multispace and Multilevel BDDC
BDDC method is the most advanced method from the Balancing family of
iterative substructuring methods for the solution of large systems of linear
algebraic equations arising from discretization of elliptic boundary value
problems. In the case of many substructures, solving the coarse problem exactly
becomes a bottleneck. Since the coarse problem in BDDC has the same structure
as the original problem, it is straightforward to apply the BDDC method
recursively to solve the coarse problem only approximately. In this paper, we
formulate a new family of abstract Multispace BDDC methods and give condition
number bounds from the abstract additive Schwarz preconditioning theory. The
Multilevel BDDC is then treated as a special case of the Multispace BDDC and
abstract multilevel condition number bounds are given. The abstract bounds
yield polylogarithmic condition number bounds for an arbitrary fixed number of
levels and scalar elliptic problems discretized by finite elements in two and
three spatial dimensions. Numerical experiments confirm the theory.Comment: 26 pages, 3 figures, 2 tables, 20 references. Formal changes onl
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