PAMELA's cosmic positron from decaying LSP in SO(10) SUSY GUT

We propose two viable scenarios explaining the recent observations on cosmic positron excess. In both scenarios, the present relic density in the Universe is assumed to be still supported by thermally produced WIMP or LSP (\chi). One of the scenarios is based on two dark matter (DM) components (\chi,X) scenario, and the other is on SO(10) SUSY GUT. In the two DM components scenario, extremely small amount of non-thermally produced meta-stable DM component [O(10^{-10}) < n_X /n_\chi] explains the cosmic positron excess. In the SO(10) model, extremely small R-parity violation for LSP decay to e^\pm is naturally achieved with a non-zero VEV of the superpartner of one right-handed neutrino (\tilde{\nu}^c) and a global symmetry.Comment: 6 pages, Talks presented in PASCOS, SUSY, and COSMO/CosPA in 201

The BKB_K Kaon Parameter in the Chiral Limit

We introduce four-point functions in the hadronic ladder resummation approach to large $N_c$ QCD Green functions. We determine the relevant one to calculate the $B_K$ kaon parameter in the chiral limit. This four-point function contains both the large momenta QCD OPE and the small momenta ChPT at NLO limits, analytically. We get $\hat B_K^\chi = 0.38 \pm 0.15$. We also give the ChPT result at NLO for the relevant four-point function to calculate $B_K$ outside the chiral limit, while the leading QCD OPE is the same as the chiral limit one.Comment: 17 page

PDB91 Systematic Literature Review of Health State Utilities for Adults With Type 1 Diabetes

Abstract not availabl

Unitarity constraints on the stabilized Randall-Sundrum scenario

Recently proposed stabilization mechanism of the Randall-Sundrum metric gives rise to a scalar radion, which couples universally to matter with a weak interaction ($\simeq 1$ TeV) scale. Demanding that gauge boson scattering as described by the effective low enerrgy theory be unitary upto a given scale leads to significant constraints on the mass of such a radion.Comment: 10 page Latex 2e file including 4 postscript figures. Accepted in Journal of Physics

BKB_K using HYP-smeared staggered fermions in Nf=2+1N_f=2+1 unquenched QCD

We present results for kaon mixing parameter $B_K$ calculated using HYP-smeared improved staggered fermions on the MILC asqtad lattices. We use three lattice spacings ($a\approx 0.12$, $0.09$ and $0.06\;$fm), ten different valence quark masses ($m\approx m_s/10-m_s$), and several light sea-quark masses in order to control the continuum and chiral extrapolations. We derive the next-to-leading order staggered chiral perturbation theory (SChPT) results necessary to fit our data, and use these results to do extrapolations based both on SU(2) and SU(3) SChPT. The SU(2) fitting is particularly straightforward because parameters related to taste-breaking and matching errors appear only at next-to-next-to-leading order. We match to the continuum renormalization scheme (NDR) using one-loop perturbation theory. Our final result is from the SU(2) analysis, with the SU(3) result providing a (less accurate) cross check. We find $B_K(\text{NDR}, \mu = 2 \text{GeV}) = 0.529 \pm 0.009 \pm 0.032$ and $\hat{B}_K =B_K(\text{RGI})= 0.724 \pm 0.012 \pm 0.043$, where the first error is statistical and the second systematic. The error is dominated by the truncation error in the matching factor. Our results are consistent with those obtained using valence domain-wall fermions on lattices generated with asqtad or domain-wall sea quarks.Comment: 37 pages, 31 figures, most updated versio

Effects of 3D-printed polycaprolactone/��-tricalcium phosphate membranes on guided bone regeneration

This study was conducted to compare 3D-printed polycaprolactone (PCL) and polycaprolactone/��-tricalcium phosphate (PCL/��-TCP) membranes with a conventional commercial collagen membrane in terms of their abilities to facilitate guided bone regeneration (GBR). Fabricated membranes were tested for dry and wet mechanical properties. Fibroblasts and preosteoblasts were seeded into the membranes and rates and patterns of proliferation were analyzed using a kit-8 assay and by scanning electron microscopy. Osteogenic differentiation was verified by alizarin red S and alkaline phosphatase (ALP) staining. An in vivo experiment was performed using an alveolar bone defect beagle model, in which defects in three dogs were covered with different membranes. CT and histological analyses at eight weeks after surgery revealed that 3D-printed PCL/��-TCP membranes were more effective than 3D-printed PCL, and substantially better than conventional collagen membranes in terms of biocompatibility and bone regeneration and, thus, at facilitating GBR. ? 2017 by the authors. Licensee MDPI, Basel, Switzerland.118Ysciescopu

Singular Cucker-Smale Dynamics

The existing state of the art for singular models of flocking is overviewed, starting from microscopic model of Cucker and Smale with singular communication weight, through its mesoscopic mean-filed limit, up to the corresponding macroscopic regime. For the microscopic Cucker-Smale (CS) model, the collision-avoidance phenomenon is discussed, also in the presence of bonding forces and the decentralized control. For the kinetic mean-field model, the existence of global-in-time measure-valued solutions, with a special emphasis on a weak atomic uniqueness of solutions is sketched. Ultimately, for the macroscopic singular model, the summary of the existence results for the Euler-type alignment system is provided, including existence of strong solutions on one-dimensional torus, and the extension of this result to higher dimensions upon restriction on the smallness of initial data. Additionally, the pressureless Navier-Stokes-type system corresponding to particular choice of alignment kernel is presented, and compared - analytically and numerically - to the porous medium equation

DNA end resection by Dna2–Sgs1–RPA and its stimulation by Top3–Rmi1 and Mre11–Rad50–Xrs2

The repair of DNA double-strand breaks (DSBs) by homologous recombination requires processing of broken ends. For repair to start, the DSB must first be resected to generate a 3′-single-stranded DNA (ssDNA) overhang, which becomes a substrate for the DNA strand exchange protein, Rad51 (ref. 1). Genetic studies have implicated a multitude of proteins in the process, including helicases, nucleases and topoisomerases. Here we biochemically reconstitute elements of the resection process and reveal that it requires the nuclease Dna2, the RecQ-family helicase Sgs1 and the ssDNA-binding protein replication protein-A (RPA). We establish that Dna2, Sgs1 and RPA constitute a minimal protein complex capable of DNA resection in vitro. Sgs1 helicase unwinds the DNA to produce an intermediate that is digested by Dna2, and RPA stimulates DNA unwinding by Sgs1 in a species-specific manner. Interestingly, RPA is also required both to direct Dna2 nucleolytic activity to the 5′-terminated strand of the DNA break and to inhibit 3′ to 5′ degradation by Dna2, actions that generate and protect the 3′-ssDNA overhang, respectively. In addition to this core machinery, we establish that both the topoisomerase 3 (Top3) and Rmi1 complex and the Mre11–Rad50–Xrs2 complex (MRX) have important roles as stimulatory components. Stimulation of end resection by the Top3–Rmi1 heterodimer and the MRX proteins is by complex formation with Sgs1 (refs 5, 6), which unexpectedly stimulates DNA unwinding. We suggest that Top3–Rmi1 and MRX are important for recruitment of the Sgs1–Dna2 complex to DSBs. Our experiments provide a mechanistic framework for understanding the initial steps of recombinational DNA repair in eukaryotes

On quantum estimation, quantum cloning and finite quantum de Finetti theorems

This paper presents a series of results on the interplay between quantum estimation, cloning and finite de Finetti theorems. First, we consider the measure-and-prepare channel that uses optimal estimation to convert M copies into k approximate copies of an unknown pure state and we show that this channel is equal to a random loss of all but s particles followed by cloning from s to k copies. When the number k of output copies is large with respect to the number M of input copies the measure-and-prepare channel converges in diamond norm to the optimal universal cloning. In the opposite case, when M is large compared to k, the estimation becomes almost perfect and the measure-and-prepare channel converges in diamond norm to the partial trace over all but k systems. This result is then used to derive de Finetti-type results for quantum states and for symmetric broadcast channels, that is, channels that distribute quantum information to many receivers in a permutationally invariant fashion. Applications of the finite de Finetti theorem for symmetric broadcast channels include the derivation of diamond-norm bounds on the asymptotic convergence of quantum cloning to state estimation and the derivation of bounds on the amount of quantum information that can be jointly decoded by a group of k receivers at the output of a symmetric broadcast channel.Comment: 19 pages, no figures, a new result added, published version to appear in Proceedings of TQC 201