893 research outputs found
Evaluation of reforestation using remote sensing techniques
The utilization of remotely sensed orbital data for forestry inventory. The study area (approximately 491,100 ha) encompasses the municipalities of Ribeirao Preto, Altinopolis, Cravinhos, Serra Azul, Luis Antonio, Sao Simao, Sant Rita do Passa Quatro and Santa Rosa do Viterbo (Sao Paulo State). Materials used were LANDSAT data from channels 5 and 7 (scale 1:250,000) and CCT's. Visual interpretation of the imagery showed that for 1977 a total of 37,766.00 ha and for 1979 38,003.75 ha were reforested with Pinus and Eucalyptus within the area under study. The results obtained show that LANDSAT data can be used efficiently in forestry inventory studies
Effect of a machine learning-based severe sepsis prediction algorithm on patient survival and hospital length of stay: a randomised clinical trial.
IntroductionSeveral methods have been developed to electronically monitor patients for severe sepsis, but few provide predictive capabilities to enable early intervention; furthermore, no severe sepsis prediction systems have been previously validated in a randomised study. We tested the use of a machine learning-based severe sepsis prediction system for reductions in average length of stay and in-hospital mortality rate.MethodsWe conducted a randomised controlled clinical trial at two medical-surgical intensive care units at the University of California, San Francisco Medical Center, evaluating the primary outcome of average length of stay, and secondary outcome of in-hospital mortality rate from December 2016 to February 2017. Adult patients (18+) admitted to participating units were eligible for this factorial, open-label study. Enrolled patients were assigned to a trial arm by a random allocation sequence. In the control group, only the current severe sepsis detector was used; in the experimental group, the machine learning algorithm (MLA) was also used. On receiving an alert, the care team evaluated the patient and initiated the severe sepsis bundle, if appropriate. Although participants were randomly assigned to a trial arm, group assignments were automatically revealed for any patients who received MLA alerts.ResultsOutcomes from 75 patients in the control and 67 patients in the experimental group were analysed. Average length of stay decreased from 13.0 days in the control to 10.3 days in the experimental group (p=0.042). In-hospital mortality decreased by 12.4 percentage points when using the MLA (p=0.018), a relative reduction of 58.0%. No adverse events were reported during this trial.ConclusionThe MLA was associated with improved patient outcomes. This is the first randomised controlled trial of a sepsis surveillance system to demonstrate statistically significant differences in length of stay and in-hospital mortality.Trial registrationNCT03015454
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VA Accountability Act of 2015 (H.R. 1994), as Reported to the House
[Excerpt] This report describes the VA Accountability Act of 2015 (H.R. 1994) as reported to the House by the Committee on Veterans Affairs on July 23 2015 and compares it to current law where appropriate. A press account has reported that Chairman Jeff Miller may meet with all committee members to seek views of the minority before floor action. As a result of this meeting, it is possible that the final bill that will go to the House floor may have some provisions that differ from those that the Committee reported.
This report provides a section-by-section description of the act
Estimation of the sugar cane cultivated area from LANDSAT images using the two phase sampling method
A two phase sampling method and the optimal sampling segment dimensions for the estimation of sugar cane cultivated area were developed. This technique employs visual interpretations of LANDSAT images and panchromatic aerial photographs considered as the ground truth. The estimates, as a mean value of 100 simulated samples, represent 99.3% of the true value with a CV of approximately 1%; the relative efficiency of the two phase design was 157% when compared with a one phase aerial photographs sample
Variáveis e modelos para estimativa da produtividade do cafeeiro a partir de Ăndices de vegetação derivados de imagens Landsat.
Abstract. Coffee fields present a specific pattern of productivity resulting in high and low production in alternated years. Branches grown the first phenological year will produce coffee beans the second phenological year. In high-production years a plant works mostly to grain-filling to the detriment of new branches which will be responsible for production the following year. In low-production years the plant works rather to grow new branches which will produce beans the subsequent year. This feature can be related to the foliar biomass, which can be estimated through remote sensing derived vegetation indices. Several studies report this feature must be incorporated in modeling coffee yield coupled with agrometeorogical models. In this paper we derived Landsat vegetation indices related to coffee plots in order to obtain relationships to yield of the same coffee plots. Biophisical variables and yield data were colected in interviews with farmers from four locations in the whole largest Brazilian coffee-exporting province. Vegetation indices and biophysical variables were selected through stepwise regression in order to obtain the best regression models to estimate coffee yield. Outcomes showed that general models and specific models obtained for Mundo Novo variety presented Pearson's correlation coeficients (r) from 0,64 to 0,71 while models for CatuaĂ variety showed better results (r = 0,85). Although coffee yield cannot be estimated exclusively from these models, they can be usefull coupled with agrometeorogical models for estimating coffee yield
Diversity in the structures and ligand binding sites of nematode fatty acid and retinol binding proteins revealed by Na-FAR-1 from Necator americanus
Fatty acid and retinol binding proteins (FARs) comprise a family of unusual α-helix rich lipid binding proteins found exclusively in nematodes. They are secreted into host tissues by parasites of plants, animals and humans. The structure of a FAR protein from the free-living nematode Caenorhabditis elegans is available, but this protein (Ce-FAR-7) is from a subfamily of FARs that does not appear to be important at the host-parasite interface. We have therefore examined Na-FAR-1 from the blood-feeding intestinal parasite of humans, Necator americanus . The three dimensional structure of Na-FAR-1 in its ligand-free and ligand-bound forms, determined by nuclear magnetic resonance spectroscopy (NMR) and X-ray crystallography, respectively, reveals an a-helical fold similar to Ce-FAR-7, but Na-FAR-1 possesses a larger and more complex internal ligand binding cavity and an additional C-terminal a-helix. Titration of apo -Na-FAR-1 with oleic acid, analysed by NMR chemical shift perturbation, reveals that at least four distinct protein:ligand complexes can be formed. Na-FAR-1, and possibly other FARs, may have a wider repertoire for hydrophobic ligand binding, as confirmed here by our finding that a range of neutral and polar lipids co-purify with the bacterial recombinant protein. Finally, we show by immunohistochemistry that Na-FAR-1 is present in adult worms with a tissue distribution indicative of possible roles in nutrient acquisition by the parasite and in reproduction in the male
Nucleotide Frequencies in Human Genome and Fibonacci Numbers
This work presents a mathematical model that establishes an interesting
connection between nucleotide frequencies in human single-stranded DNA and the
famous Fibonacci's numbers. The model relies on two assumptions. First,
Chargaff's second parity rule should be valid, and, second, the nucleotide
frequencies should approach limit values when the number of bases is
sufficiently large. Under these two hypotheses, it is possible to predict the
human nucleotide frequencies with accuracy. It is noteworthy, that the
predicted values are solutions of an optimization problem, which is commonplace
in many nature's phenomena.Comment: 12 pages, 2 figure
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Abortion Law Development: A Brief Overview
This report offers an overview of the development of abortion law from 1973 to the present. Beginning with a brief discussion of the historical background, the report analyzes the leading Supreme Court decisions over the past twenty-eight years, emphasizing particularly the landmark decisions in Roe and Doe, the Court’s shift
in direction in Webster v. Reproductive Health Services and Planned Parenthood of Southeastern Pennsylvania v. Casey, and the Court’s most recent decision on abortion, Stenberg v. Carhart. The Court’s decisions on the constitutionality of restricting public funding for abortion are also discussed
Effects of telmisartan and ramipril on adiponectin and blood pressure in patients with type 2 diabetes
<b>Background:</b>
Adiponectin is secreted by adipose tissue and may play a role in cardiovascular disease. We examined adiponectin levels in patients with type 2 diabetes who participated in the Telmisartan vs. Ramipril in Renal Endothelial Dysfunction (TRENDY) study.
<b>Methods</b>
A total of 87 patients were assessed at baseline and following 9 weeks treatment with the angiotensin-receptor blocker telmisartan (final dose, 80 mg; n = 45) or the angiotensin-converting enzyme inhibitor ramipril (final dose, 10 mg; n = 42). Adiponectin levels were measured in plasma by radioimmunoassay.
<b>Results:</b>
Adiponectin levels were inversely correlated with systolic (SBP; r = -0.240, P < 0.05) and diastolic (DBP; r = -0.227, P < 0.05) blood pressure at baseline and following treatment with telmisartan or ramipril (SBP: r = -0.228, P < 0.05; DBP: r = -0.286, P < 0.05). Changes in adiponectin levels were related to changes in SBP (r = -0.357, P < 0.01) and DBP (r = -0.286, P < 0.01). There was a significant increase in adiponectin levels in the telmisartan (0.68 (95% confidence interval (CI), 0.27 to 1.10) <sup>µ</sup>g/ml, P < 0.01) but not in the ramipril group (0.17 (95% CI, -0.56 to 0.90) <sup>µ</sup>g/ml, P = 0.67). Blood pressure reduction in the telmisartan group (DeltaSBP: -13.5 (95% CI, -17.0 to -10.0) mm Hg; ΔDBP: -7.6 (95% CI, -9.8 to -5.3) mm Hg, each P < 0.001) was significantly (P less than or equal to 0.01 for SBP and P < 0.01 for DBP) greater than in the ramipril group (ΔSBP: -6.1 (95% CI, -6.2 to -2.0) mm Hg; ΔDBP: -2.7 (95% CI, -5.0 to -0.5) mm Hg; P < 0.01 and P < 0.05, respectively).
<b>Conclusion:</b>
Adiponectin is correlated with blood pressure in patients with type 2 diabetes. Whether increased adiponectin contributes to the blood pressure–lowering effect of telmisartan needs further study
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