Consciousness in the Universe is Scale Invariant and Implies an Event Horizon of the Human Brain

Our brain is not a "stand alone" information processing organ: it acts as a central part of our integral nervous system with recurrent information exchange with the entire organism and the cosmos. In this study, the brain is conceived to be embedded in a holographic structured field that interacts with resonant sensitive structures in the various cell types in our body. In order to explain earlier reported ultra-rapid brain responses and effective operation of the meta-stable neural system, a field-receptive mental workspace is proposed to be communicating with the brain. Our integral nervous system is seen as a dedicated neural transmission and multi-cavity network that, in a non-dual manner, interacts with the proposed supervening meta-cognitive domain. Among others, it is integrating discrete patterns of eigen-frequencies of photonic/solitonic waves, thereby continuously updating a time-symmetric global memory space of the individual. Its toroidal organization allows the coupling of gravitational, dark energy, zero-point energy field (ZPE) as well as earth magnetic fields energies and transmits wave information into brain tissue, that thereby is instrumental in high speed conscious and sub-conscious information processing. We propose that the supposed field-receptive workspace, in a mutual interaction with the whole nervous system, generates self-consciousness and is conceived as operating from a 4th spatial dimension (hyper-sphere). Its functional structure is adequately defined by the geometry of the torus, that is envisioned as a basic unit (operator) of space-time. The latter is instrumental in collecting the pattern of discrete soliton frequencies that provided an algorithm for coherent life processes, as earlier identified by us. It is postulated that consciousness in the entire universe arises through, scale invariant, nested toroidal coupling of various energy fields, that may include quantum error correction. In the brain of the human species, this takes the form of the proposed holographic workspace, that collects active information in a "brain event horizon", representing an internal and fully integral model of the self. This brain-supervening workspace is equipped to convert integrated coherent wave energies into attractor type/standing waves that guide the related cortical template to a higher coordination of reflection and action as well as network synchronicity, as required for conscious states. In relation to its scale-invariant global character, we find support for a universal information matrix, that was extensively described earlier, as a supposed implicate order as well as in a spectrum of space-time theories in current physics. The presence of a field-receptive resonant workspace, associated with, but not reducible to, our brain, may provide an interpretation framework for widely reported, but poorly understood transpersonal conscious states and algorithmic origin of life. It also points out the deep connection of mankind with the cosmos and our major responsibility for the future of our planet.</p

Assessment of bone ingrowth potential of biomimetic hydroxyapatite and brushite coated porous E-beam structures

The bone ingrowth potential of biomimetic hydroxyapatite and brushite coatings applied on porous E-beam structure was examined in goats and compared to a similar uncoated porous structure and a conventional titanium plasma spray coating. Specimens were implanted in the iliac crest of goats for a period of 3 (4 goats) or 15 weeks (8 goats). Mechanical implant fixation generated by bone ingrowth was analyzed by a push out test. Histomorphometry was performed to assess the bone ingrowth depth and bone implant contact. The uncoated and hydroxyapatite-coated cubic structure had significantly higher mechanical strength at the interface compared to the Ti plasma spray coating at 15 weeks of implantation. Bone ingrowth depth was significantly larger for the hydroxyapatite- and brushite-coated structures compared to the uncoated structure. In conclusion, the porous E-beam surface structure showed higher bone ingrowth potential compared to a conventional implant surface after 15 weeks of implantation. Addition of a calcium phosphate coating to the E-beam structure enhanced bone ingrowth significantly. Furthermore, the calcium phosphate coating appears to work as an accelerator for bone ingrowth

The beneficial effect of hydroxyapatite lasts: A randomized radiostereometric trial comparing hydroxyapatite-coated, uncoated, and cemented tibial components for up to 16 years

Analysis and Stochastic

Reproducibility of goniometric measurement of the knee in the in-hospital phase following total knee arthroplasty

<p>Abstract</p> <p>Background</p> <p>The objective of the present study was to assess interobserver reproducibility (in terms of reliability and agreement) of active and passive measurements of knee RoM using a long arm goniometer, performed by trained physical therapists in a clinical setting in total knee arthroplasty patients, within the first four days after surgery.</p> <p>Methods</p> <p>Test-retest analysis</p> <p>Setting: University hospital departments of orthopaedics and physical therapy</p> <p>Participants: Two experienced physical therapists assessed 30 patients, three days after total knee arthroplasty.</p> <p>Main outcome measure: RoM measurement using a long-arm (50 cm) goniometer</p> <p>Agreement was calculated as the mean difference between observers ± 95% CI of this mean difference. The intraclass correlation coefficient (ICC) was calculated as a measure of reliability, based on two-way random effects analysis of variance.</p> <p>Results</p> <p>The lowest level of agreement was that for measurement of passive flexion with the patient in supine position (mean difference 1.4°; limits of agreement 16.2° to 19° for the difference between the two observers. The highest levels of agreement were found for measurement of passive flexion with the patient in sitting position and for measurement of passive extension (mean difference 2.7°; limits of agreement -6.7 to 12.1 and mean difference 2.2°; limits of agreement -6.2 to 10.6 degrees, respectively). The ability to differentiate between subjects ranged from 0.62 for measurement of passive extension to 0.89 for measurements of active flexion (ICC values).</p> <p>Conclusion</p> <p>Interobserver agreement for flexion as well as extension was only fair. When two different observers assess the same patients in the acute phase after total knee arthroplasty using a long arm goniometer, differences in RoM of less than eight degrees cannot be distinguished from measurement error. Reliability was found to be acceptable for comparison on group level, but poor for individual comparisons over time.</p

Cell-Based Bone Tissue Engineering

The authors review the available data on bone tissue engineering and discuss possible new research areas that could help to make bone tissue engineering a clinical success

Genetic correlations between wool traits and carcass traits in Merino sheep

Genetic correlations between 29 wool production and quality traits and 14 whole carcass measures and carcass component traits were estimated from the Information Nucleus of 8 flocks managed across a range of Australian sheep production environments and genetically linked. Wool data were from over 5,000 Merino progeny born over 5 yr, whereas carcass data were from over 1,200 wether progeny of over 176 sires, slaughtered at about 21 kg carcass weight, on average. Wool traits included yearling and adult records for wool weight, fiber diameter, fiber diameter variation, staple strength, scoured color, and visual scores for breech and body wrinkle. Whole carcass measures included HCW, dressing percentage (DP), and various measures of fat depth and eye muscle dimensions. Carcass components were obtained by dissection, and lean meat yield (LMY) was predicted. Heritability estimates for whole carcass measures ranged from 0.12 ± 0.08 to 0.35 ± 0.10 and ranged from 0.17 ± 0.10 to 0.46 ± 0.10 for carcass dissection traits, with no evidence of important genotype × environment interactions. Genetic correlations indicated that selection for increased clean wool weight will result in reduced carcass fat (−0.17 to −0.34) and DP (−0.48 ± 0.15), with little effect on carcass muscle. Selection for lower fiber diameter will reduce HCW (−0.48 ± 0.15) as well as carcass fat (0.14 to 0.27) and muscle (0.21 to 0.50). There were high genetic correlations between live animal measures of fat and muscle depth and the carcass traits (generally greater than 0.5 in size). Selection to increase HCW (and DP) will result in sheep with fewer wrinkles on the body (−0.57 ± 0.10) and barer breeches (−0.74 ± 0.12, favorable), with minor deterioration in scoured wool color (reduced brightness and increased yellowness). Selection for reduced fat will also result in sheep with fewer body wrinkles (−0.42 to −0.79). Increasing LMY in Merinos through selection would result in a large reduction in carcass fat and DP (−0.66 to −0.84), with a smaller increase in carcass muscle and some increase in wool weight and wrinkles. Although no major antagonisms are apparent between the wool and carcass traits, developing selection indexes for dual-purpose wool and meat breeding objectives will require accurate estimates of genetic parameters to ensure that unfavorable relationships are suitably considered. The findings will aid development of dual-purpose wool and meat breeding objectives