Identification of a recurring bacterial contaminant in a spacecraft watering system

Bacterial contaminant in Biosatellite water syste

The Manchester occulting mask imager (MOMI) - first results on the environment of P Cygni

The design and first use of the Manchester occulting mask imager (MOMI) is described. This device, when combined with the Cassegrain or Ritchey-Chretien foci of large telescopes, is dedicated to the imagery of faint line emission regions around bright central sources. Initial observations, with MOMI on the Nordic Optical telescope (NOT), of the V=4.8 mag P~Cygni environment, have revealed a $\geq$~5~arcmin long [NII] 6584A emitting filament projecting from the outer nebular shell of this luminous blue variable (LBV) star. The presence of a mono-polar lobe older than both the inner (22 arcsec diameter) and outer (1.6 arcmin diameter) shells is suggested.Comment: 4 pages, 4 figures, accepted MNRAS 1998 June 1

Engineering a flux-dependent mobility edge in disordered zigzag chains

There has been great interest in realizing quantum simulators of charged particles in artificial gauge fields. Here, we perform the first quantum simulation explorations of the combination of artificial gauge fields and disorder. Using synthetic lattice techniques based on parametrically-coupled atomic momentum states, we engineer zigzag chains with a tunable homogeneous flux. The breaking of time-reversal symmetry by the applied flux leads to analogs of spin-orbit coupling and spin-momentum locking, which we observe directly through the chiral dynamics of atoms initialized to single lattice sites. We additionally introduce precisely controlled disorder in the site energy landscape, allowing us to explore the interplay of disorder and large effective magnetic fields. The combination of correlated disorder and controlled intra- and inter-row tunneling in this system naturally supports energy-dependent localization, relating to a single-particle mobility edge. We measure the localization properties of the extremal eigenstates of this system, the ground state and the most-excited state, and demonstrate clear evidence for a flux-dependent mobility edge. These measurements constitute the first direct evidence for energy-dependent localization in a lower-dimensional system, as well as the first explorations of the combined influence of artificial gauge fields and engineered disorder. Moreover, we provide direct evidence for interaction shifts of the localization transitions for both low- and high-energy eigenstates in correlated disorder, relating to the presence of a many-body mobility edge. The unique combination of strong interactions, controlled disorder, and tunable artificial gauge fields present in this synthetic lattice system should enable myriad explorations into intriguing correlated transport phenomena.Comment: 10 pages, 5 figures, 5 pages of supplementary materials; updated version has additional dat

An assessment of the quality of the I-DSD and the I-CAH registries - international registries for rare conditions affecting sex development

With the proliferation of rare disease registries, there is a need for registries to undergo an assessment of their quality against agreed standards to ensure their long-term sustainability and acceptability.This study was performed to evaluate the I-DSD and I-CAH Registries and identify their strengths and weaknesses. The design and operational aspects of the registries were evaluated against published quality indicators. Additional criteria included the level of activity, international acceptability of the registries and their use for research. The design of the I-DSD and I-CAH Registries provides them with the ability to perform multiple studies and meet the standards for data elements, data sources and eligibility criteria. The registries follow the standards for data security, governance, ethical and legal issues, sustainability and communication of activities. The data have a high degree of validity, consistency and accuracy and the completeness is maximal for specific conditions such as androgen insensitivity syndrome and congenital adrenal hyperplasia. In terms of research output, the external validity is strong but the wide variety of cases needs further review. The internal validity of data was condition specific and highest for conditions such as congenital adrenal hyperplasia. The shift of the registry from a European registry to an international registry and the creation of a discrete but linked CAH registry increased the number of users and stakeholders as well as the international acceptability of both registries. The I-DSD and I-CAH registries comply with the standards set by expert organisations. Recent modifications in their operation have allowed the registries to increase their user acceptability