Characterization of digital dispersive spectrometers by low coherence interferometry

We propose a procedure to determine the spectral response of digital dispersive spectrometers without previous knowledge of any parameter of the system. The method consists of applying the Fourier transform spectroscopy technique to each pixel of the detection plane, a CCD camera, to obtain its individual spectral response. From this simple procedure, the system-point spread function and the effect of the finite pixel width are taken into account giving rise to a response matrix that fully characterizes the spectrometer. Using the response matrix information we find the resolving power of a given spectrometer, predict in advance its response to any virtual input spectrum and improve numerically the spectrometer's resolution. We consider that the presented approach could be useful in most spectroscopic branches such as in computational spectroscopy, optical coherence tomography, hyperspectral imaging, spectral interferometry and analytical chemistry, among others.Fil: Martínez Matos, Ó.. Universidad Complutense de Madrid; EspañaFil: Rickenstorff, C.. Universidad Complutense de Madrid; EspañaFil: Zamora, S.. Universidad Complutense de Madrid; EspañaFil: Izquierdo, J. G.. Universidad Complutense de Madrid; EspañaFil: Vaveliuk, Pablo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Investigaciones Ópticas. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Centro de Investigaciones Ópticas. Universidad Nacional de La Plata. Centro de Investigaciones Ópticas; Argentin

Price, Wage and Employment Response to Shocks: Evidence from the WDN Survey

This paper analyses information from survey data collected in the framework of the Eurosystem's Wage Dynamics Network (WDN) on patterns of firm-level adjustment to shocks. We document that the relative intensity and the character of price vs. cost and wage vs. employment adjustments in response to cost-push shocks depend - in theoretically sensible ways - on the intensity of competition in firms' product markets, on the importance of collective wage bargaining and on other structural and institutional features of firms and of their environment. Focusing on the pass-through of cost shocks to prices, our results suggest that the pass-through is lower in highly competitive firms. Furthermore, a high degree of employment protection and collective wage agreements tend to make this pass-through stronger.Wage bargaining, Labour-market institutions, Survey data, European Union.

Interdisciplinary and International Workshop as Technological Design Method Focused on the European Ods Strategy

The innovative rules of the Europe 2020 Strategy, which follow the Lisbon Strategy (2000) and the Copenhagen Declaration (2002), promote smart and sustainable growth through the promotion of lowpollutant, resource-efficient and effective project strategies for improving human, social and environmental conditions. This paper illustrates the workshop design experience conducted in collaboration between the Escuela Superior de Edificacion (ETSEM) of the Universidad Politecnica de Madrid, the Department of Civil, Building and Environmental Engineering (DICEA) of Università di Napoli "Federico II" and the Department of Architecture and Industrial Design (DADI) of Università della Campania "L. Vanvitelli", focusing on the added value for the three research groups to integrate different teaching methods according that strategies

Virtual libraries of tissue and clinical samples: potential role of a 3-D microscope.

Our international innovative teaching group from different European Universities (De Montfort University, DMU, UK; and the Spanish University of Alcalá, University Miguel Hernández and University of San Pablo CEU), in conjunction with practicing biomedical scientists in the National Health Service (UK) and biomedical researchers, are developing two complete e-learning packages for teaching and learning medical parasitology, named DMU e-Parasitology (accessible at: http://parasitology.dmu.ac.uk), and biology and chemistry, named DMU e-Biology (accessible at: http://parasitology.dmu.ac.uk/ebiology/index.htm), respectively. Both packages will include a virtual microscope with a complete library of digitised tissue images, clinical slides and cell culture slides/mini-videos for enhancing the teaching and learning of a myriad of techniques applicable to health science undergraduate and postgraduate students. Thus, these packages include detecting human parasites, by becoming familiar with their infective structures and/or organs (e.g. eggs, cysts) and/or explore pathogenic tissues stained with traditional (e.g. haematoxylin & eosin) or more modern (e.g. immunohistochemistry) techniques. The Virtual Microscope (VM) module in the DMU e-Parasitology package is almost completed (accessible at: http://parasitology.dmu.ac.uk/learn/microscope.htm) and contains a section for the three major groups of human-pathogenic parasites (Peña-Fernández et al., 2018) [1]. Digitised slides are provided with the functionality of a microscope by using the gadget Zoomify®, and we consider that they can enhance learning, as previous studies reported in the literature have reported similar sensitivity and specificity rates for identification of parasites for both digitised and real slides. The DMU e-Biology’s VM, currently in development, will provide healthy and pathological tissue samples from a range of mammalian tissues and organs. This communication will provide a description of both virtual libraries and the process of developing them. In conjunction, we will use a three-dimensional (3D) super-resolution microscopy, 3D Cell Explorer (Nanolive, Lausanne, Switzerland), to incorporate potential 3D microscopic photographs/short videos of cells to provide students with information about the spatial arrangement and morphologies of cells that are essential for life

Blurred Lines Between Competition and Parasitism

Accurately describing the ecological relationships between species is more than mere semantics-doing so has profound practical and applied implications, not the least of which is that inaccurate descriptions can lead to fundamentally incorrect predicted outcomes of community composition and functioning. Accurate ecological classifications are particularly important in the context of global change, where species interactions can change rapidly following shifts in species composition. Here, we argue that many common ecological interactions-particularly competition and parasitism-can be easily confused and that we often lack empirical evidence for the full reciprocal interaction among species. To make our case and to propose a theoretical framework for addressing this problem, we use the interactions between lianas and trees, whose outcomes have myriad implications for the ecology and conservation of tropical forests (e.g., Schnitzer et al. 2015)

On domain walls in a Ginzburg-Landau non-linear S^2-sigma model

The domain wall solutions of a Ginzburg-Landau non-linear $S^2$-sigma hybrid model are unveiled. There are three types of basic topological walls and two types of degenerate families of composite - one topological, the other non-topological- walls. The domain wall solutions are identified as the finite action trajectories (in infinite time) of a related mechanical system that is Hamilton-Jacobi separable in sphero-conical coordinates. The physical and mathematical features of these domain walls are thoroughly discussed.Comment: 26 pages, 18 figure

Synapse development is regulated by microglial THIK-1 K+ channels

Microglia are the resident immune cells of the central nervous system. They constantly survey the brain parenchyma for redundant synapses, debris, or dying cells, which they remove through phagocytosis. Microglial ramification, motility, and cytokine release are regulated by tonically active THIK-1 K+ channels on the microglial plasma membrane. Here, we examined whether these channels also play a role in phagocytosis. Using pharmacological blockers and THIK-1 knockout (KO) mice, we found that a lack of THIK-1 activity approximately halved both microglial phagocytosis and marker levels for the lysosomes that degrade phagocytically removed material. These changes may reflect a decrease of intracellular [Ca2+]i activity, which was observed when THIK-1 activity was reduced, since buffering [Ca2+]i reduced phagocytosis. Less phagocytosis is expected to result in impaired pruning of synapses. In the hippocampus, mice lacking THIK-1 expression had an increased number of anatomically and electrophysiologically defined glutamatergic synapses during development. This resulted from an increased number of presynaptic terminals, caused by impaired removal by THIK-1 KO microglia. The dependence of synapse number on THIK-1 K+ channels, which control microglial surveillance and phagocytic ability, implies that changes in the THIK-1 expression level in disease states may contribute to altering neural circuit function

Famous architectures in urban contexts: the impact of colours and materials

Architecture is not just a container or a place in which it is possible to perform functions; architecture is everything that surrounds us, it is the space in which we immerse ourselves and with which we communicate. It is not the shape of the project that first influences our perception of space, whether it is open or closed, but the colours and materials that characterise and define it, making it harmonious and pleasant or, in the opposite way, hostile and inhospitable. In 1981 the UNI 8289:1981 "Construction. Needs of the final user. Classification" defined the term "well-being" as "the set of conditions relating to states of the building system appropriate to life, to health, to the performance of the users' activities", how do colours and materials contribute to the conditions of well-being? Which are the targets that can be achieved through the wise use of these elements? The aim of this work is to analyse the application of colours and materials in famous architectures in order to determinate the impact at urban and human level, how they dialogue with the context and how they dialogue with human perceptions, identifying three directions of intervention: colour and materials as anthropomorphic relation, colours and materials as pictorial support, colour and materials as function

Characterization of digital dispersive spectrometers by low coherence interferometry

We propose a procedure to determine the spectral response of digital dispersive spectrometers without previous knowledge of any parameter of the system. The method consists of applying the Fourier transform spectroscopy technique to each pixel of the detection plane, a CCD camera, to obtain its individual spectral response. From this simple procedure, the system-point spread function and the effect of the finite pixel width are taken into account giving rise to a response matrix that fully characterizes the spectrometer. Using the response matrix information we find the resolving power of a given spectrometer, predict in advance its response to any virtual input spectrum and improve numerically the spectrometer's resolution. We consider that the presented approach could be useful in most spectroscopic branches such as in computational spectroscopy, optical coherence tomography, hyperspectral imaging, spectral interferometry and analytical chemistry, among others.Facultad de Ciencias ExactasCentro de Investigaciones Óptica

Characterization of digital dispersive spectrometers by low coherence interferometry

We propose a procedure to determine the spectral response of digital dispersive spectrometers without previous knowledge of any parameter of the system. The method consists of applying the Fourier transform spectroscopy technique to each pixel of the detection plane, a CCD camera, to obtain its individual spectral response. From this simple procedure, the system-point spread function and the effect of the finite pixel width are taken into account giving rise to a response matrix that fully characterizes the spectrometer. Using the response matrix information we find the resolving power of a given spectrometer, predict in advance its response to any virtual input spectrum and improve numerically the spectrometer's resolution. We consider that the presented approach could be useful in most spectroscopic branches such as in computational spectroscopy, optical coherence tomography, hyperspectral imaging, spectral interferometry and analytical chemistry, among others.Facultad de Ciencias ExactasCentro de Investigaciones Óptica