1,218 research outputs found
Sedimentary mechanisms of a modern banded iron formation on Milos Island, Greece
An Early Quaternary shallow submarine hydrothermal iron formation (IF) in the Cape Vani sedimentary basin (CVSB) on Milos Island, Greece, displays banded rhythmicity similar to Precambrian banded iron formation (BIF). Sedimentary, stratigraphic reconstruction, biogeochemical analysis and micro-nanoscale mineralogical characterization confirms the Milos rocks as modern Precambrian BIF analogues. Spatial coverage of the BIF-type rocks in relation to the economic grade Mn ore that brought prominence to the CVSB implicates tectonic activity and changing redox in the deposition of the BIF-type rocks. Field-wide stratigraphic and biogeochemical reconstruction demonstrates two temporal and spatially isolated iron deposits in the CVSB with distinct sedimentological character. Petrographic screening suggest the previously described photoferrotrophic-like microfossil-rich IF (MFIF), accumulated on basement andesite in a ~â150âm wide basin, in the SW margin of the basin. A strongly banded non-fossiliferous IF (NFIF) caps the Mn-rich sandstones at the transition to the renowned Mn-rich formation. Geochemical evidence relates the origin of the NFIF to periodic submarine volcanism and water column oxidation of released Fe(II) in conditions apparently predominated by anoxia, similar to the MFIF. This is manifested in the lack of shale-normalized Ce anomalies. Raman spectroscopy pairs hematite-rich grains in the NFIF with relics of a carbonaceous material carrying an average ÎŽ13Corg signature of ~ââ25ââ°. However, a similar ÎŽ13Corg signature in the MFIF is not directly coupled to hematite by mineralogy. The NFIF, which post dates large-scale Mn deposition in the CVSB, is composed primarily of amorphous Si (opal-SiO2â·ânH2O) while crystalline quartz (SiO2) predominates the MFIF. An intricate interaction between tectonic processes, changing redox, biological activity and abiotic Si precipitation, formed the unmetamorphosed BIF-type deposits
Effects of access to feed, water, and a competitive exclusion product in the hatcher on some immune traits and gut development in broiler chickens
1. This study evaluated the effect of access to feed, water, and the competitive exclusion (CE) product Broilact((R)), administered in the hatcher, on broiler performance, caecal microbiota development, organ development, intestinal morphology, serum levels of IgY and vaccine-induced antibody responses.2. In total, 250 chicks were hatched in a HatchCare (TM) hatcher and divided into four groups, given access to feed, water and the CE product sprayed on the chicks (CEs); access to feed, water, and the CE product in water (CEw); access to feed and water (Cpos); or no access to feed and water (Cneg) in the hatcher.3. At the research facility, 10 chicks per hatching treatment were euthanised for organ measurements. The remaining 200 chicks were randomly distributed to 20 pens. On d 11, all birds were vaccinated against avian pneumovirus (APV). Three focal birds per pen were blood-sampled weekly for quantification of IgY and serum antibodies to APV. On d 11 and 32, two birds per replicate pen were euthanised for organ measurements and sample collection. Feed intake and body weight were recorded weekly.4. Delayed access to feed and water reduced weight gain and feed intake early in life. At the end of the study, no differences in body weight remained.5. There were some early effects on organs, with depressed intestinal development and higher relative gizzard weight for the Cneg group at placement. No treatment effects on the immune traits measured were detected.6. The relative abundance of seven bacterial genera differed between treatment groups at d 11 of age. The results suggested that chickens are capable of compensating for 40 h feed and water deprival post-hatch. Provision of Broilact((R)) did not have any persistent performance-enhancing properties, although different outcomes under rearing conditions closer to commercial production cannot be ruled out
The intensity paradox:A systematic review and metaâanalysis of its impact on the cardiorespiratory fitness of older adults
Aim: The present systematic review and metaâanalysis aimed to compare the effect of moderateâ versus highâintensity aerobic exercise on cardiorespiratory fitness (CRF) in older adults, taking into account the volume of exercise completed. Methods: The databases MEDLINE (Ovid), EMBASE (Ovid), and CENTRAL (Cochrane Library) were searched to identify randomized controlled trials (RCTs). Two reviewers extracted data and assessed bias. Comprehensive MetaâAnalysis software calculated overall effect size, intensity differences, and performed metaâregression analyses using preâtoâpost intervention or change scores of peak oxygen uptake (VÌO2peak). The review included 23 RCTs with 1332 older adults (intervention group: n = 932; control group: n = 400), divided into moderateâintensity (435 older adults) and highâintensity (476 older adults) groups. Results: Metaâregression analysis showed a moderate, but not significant, relationship between exercise intensity and improvements in VÌO2peak after accounting for the completed exercise volume (ÎČ = 0.31, 95% CI = [â0.04; 0.67]). Additionally, studies comparing moderateâ versus highâintensity revealed a small, but not significant, effect in favor of highâintensity (Hedges' g = 0.20, 95% CI = [â0.02; 0.41]). Finally, no significant differences in VÌO2peak improvements were found across exercise groups employing various methods, modalities, and intensity monitoring strategies. Conclusion: Findings challenge the notion that highâintensity exercise is inherently superior and indicate that regular aerobic exercise, irrespective of the specific approach and intensity, provides the primary benefits to CRF in older adults. Future RCTs should prioritize valid and reliable methodologies for monitoring and reporting exercise volume and adherence among older adults
Investigation of frontal lobe activation with fNIRS and systemic changes during video gaming.
Frontal lobe activation caused by tasks such as videogames can be investigated using multichannel near-infrared spectroscopy (fNIRS), sometimes called optical topography. The aims of this study are to investigate the effects of video gaming (fighting and puzzle games) in the brain and the systemic physiology and to determine whether systemic responses during the gaming task are associated with the measurement of localised cerebral haemodynamic changes as measured by fNIRS. We used a continuous-wave 8-channel fNIRS system to measure the changes in concentration of oxy-haemoglobin (HbO2) and deoxy-haemoglobin (HHb) and changes in total haemoglobin (ÎtHb = ÎHbO2 + ÎHHb) over the frontal lobe in 30 healthy volunteers. The Portapres system was used to measure mean blood pressure (MBP) and heart rate (HR), and a laser Doppler was employed to measure the changes in scalp blood flow (or flux). Even though we observed significant changes in systemic variables during gaming, in particular in scalp flow, we also managed to see localised activation patterns over the frontal polar (FP1) region. However, in some channels over the frontal lobe, we also observed significant correlations between the HbO2 and systemic variables
The role of domain-specific and domain-general cognitive functions and skills in sports performance: A meta-analysis
Cognition plays a key role in sports performance. In this meta-analytic review, we synthesize research that has examined the relationship between cognitive functions, skills, and sports performance. We identified literature by searching Cochrane library, PsychInfo, Pubmed, and Web of Science. We included studies conducted on competitive athletes, assessed cognitive prerequisites, and included performance measures related to the sport. Of the 9433 screened records, 136 reports were included, containing 142 studies, 1227 effect sizes, and 8860 participants. Only 11 studies used a prospective study design. The risk of bias was assessed using The Risk of Bias Assessment Tool for Nonrandomized Studies. The multilevel meta- analysis showed a medium effect size for the overall difference in cognitive functions and skills, with higher-skilled athletes scoring better than lower-skilled athletes (Hedgesâ g = 0.59, 95% CI [0.49, 0.69]). The moderator analysis showed larger effect size for tests of cognitive decision-making skills (g = 0.77, 95% CI [0.6, 0.94]) compared to basic (g = 0.39, 95% CI [0.21, 0.56]) and higher cognitive functions (g = 0.44, 95% CI [0.26, 0.62]), as well as larger effect size for sport-specific task-stimuli compared to general ones. We report that higher-skilled athletes perform better on tests of cognitive function compared to lower-skilled athletes. There was insufficient evidence to determine whether cognitive functions and skills can predict future sport performance. We found no evidence to support claims that tests of general cognitive functions, such as executive functioning, should be used by practitioners for talent identification or player selection
An interpolation theorem for proper holomorphic embeddings
Given a Stein manifold X of dimension n>1, a discrete sequence a_j in X, and
a discrete sequence b_j in C^m where m > [3n/2], there exists a proper
holomorphic embedding of X into C^m which sends a_j to b_j for every j=1,2,....
This is the interpolation version of the embedding theorem due to Eliashberg,
Gromov and Schurmann. The dimension m cannot be lowered in general due to an
example of Forster
HIIT at Home:Enhancing Cardiorespiratory Fitness in Older AdultsâA Randomized Controlled Trial
Background: This study aimed to investigate the effectiveness of a 6âmonth homeâbased highâintensity interval training (HIIT) intervention to improve peak oxygen consumption (VÌO2peak) and lactate threshold (LT) in older adults. Methods: Two hundred thirtyâthree healthy older adults (60â84 years; 54% females) were randomly assigned to either 6âmonth, thriceâweekly homeâbased HIIT (onceâweekly circuit training and twiceâweekly interval training) or a passive control group. Exercise sessions were monitored using a Polar watch and a logbook for objective and subjective data, respectively, and guided by a personal coach. The outcomes were assessed using a modified Balke protocol combining VÌO2peak and LT measures. General linear regression models assessed betweenâgroup differences in change and withinâgroup changes for each outcome. Results: There was a significant betweenâgroup difference in the preâtoâpost change in VÌO2peak (difference: 1.8 [1.2; 2.3] mL/kg/min; exercise: +1.4 [1.0; 1.7] mL/kg/min [~5%]; control: â0.4 [â0.8; â0.0] mL/kg/min [approximately â1.5%]; effect size [ES]: 0.35). Compared with controls, the exercise group had lower blood lactate concentration (â0.7 [â0.9; â0.4] mmol/L, ES: 0.61), % of peak heart rate (â4.4 [â5.7; â3.0], ES: 0.64), and % of VÌO2peak (â4.5 [â6.1; â2.9], ES: 0.60) at the intensity corresponding to preintervention LT and achieved a higher treadmill stage (% incline) at LT (0.6 [0.3; 0.8]; ES: 0.47), following the intervention. Conclusion: This study highlights the effectiveness of a homeâbased HIIT intervention as an accessible and equipmentâminimal strategy to induce clinically meaningful improvements in cardiorespiratory fitness in older adults. Over 6 months, the exercise group showed larger improvements in all outcomes compared with the control group. Notably, the LT outcome exhibited a more pronounced magnitude of change than VÌO2peak
Human white adipose tissue vasculature contains endothelial colony-forming cells with robust in vivo vasculogenic potential
Epub ahead of print.-- The final publication is available at link.springer.comBlood-derived endothelial colony-forming cells (ECFCs) have robust vasculogenic potential that
can be exploited to bioengineer long-lasting human vascular networks in vivo. However,
circulating ECFCs are exceedingly rare in adult peripheral blood. Because the mechanism by
which ECFCs are mobilized into circulation is currently unknown, the reliability of peripheral
blood as a clinical source of ECFCs remains a concern. Thus, there is a need to find alternative
sources of autologous ECFCs. Here we aimed to determine whether ECFCs reside in the
vasculature of human white adipose tissue (WAT) and to evaluate if WAT-derived ECFCs
(watECFCs) have equal clinical potential to blood-derived ECFCs. We isolated the complete
endothelial cell (EC) population from intact biopsies of normal human subcutaneous WAT by
enzymatic digestion and selection of CD31+ cells. Subsequently, we extensively compared
WAT-derived EC phenotype and functionality to bonafide ECFCs derived from both umbilical
cord blood and adult peripheral blood. We demonstrated that human WAT is indeed a
dependable source of ECFCs with indistinguishable properties to adult peripheral blood ECFCs,
including hierarchical clonogenic ability, large expansion potential, stable endothelial phenotype,
and robust in vivo blood vessel-forming capacity. Considering the unreliability and low rate of
occurrence of ECFCs in adult blood and that biopsies of WAT can be obtained with minimal
intervention in an ambulatory setting, our results indicate WAT as a more practical alternative to
obtain large amounts of readily available autologous ECFCs for future vascular cell therapies.This work was supported by a
National Institutes of Health Grant (R00EB009096, J. M.-M).Peer reviewe
Precipitation of Mn Oxides in Quaternary microbially induced sedimentary structures (MISS), Cape Vani Paleo-Hydrothermal Vent Field, Milos, Greece
Understanding microbial mediation in sediment-hosted Mn deposition has gained importance in low-temperature ore genesis research. Here we report Mn oxide ores dominated by todorokite, vernadite, hollandite, and manjiroite, which cement Quaternary microbially induced sedimentary structures (MISS) developed along bedding planes of shallow-marine to tidal-flat volcaniclastic sandstones/sandy tuffs, Cape Vani paleo-hydrothermal vent field, Milos, Greece. This work aims to decipher the link between biological Mn oxide formation, low-T hydrothermalism, and, growth and preservation of Mn-bearing MISS (MnMISS). Geobiological processes, identified by microtexture petrography, scanning and transmission electron microscopy, lipid biomarkers, bulk- and lipid-specific ÎŽ13Corganic composition, and field data, and, low-temperature hydrothermal venting of aqueous Mn2+ in sunlit shallow waters, cooperatively enabled microbially-mediated Mn (II) oxidation and biomineralization. The MnMISS biomarker content and ÎŽ13Corg signatures strongly resemble those of modern Mn-rich hydrothermal sediments, Milos coast. Biogenic and syngenetic Mn oxide precipitation established by electron paramagnetic resonance (EPR) spectroscopy and petrography, combined with hydrothermal fluid flow-induced pre-burial curing/diagenesis, may account for todayâs crystalline Mn oxide resource. Our data suggests that MISS are not unique to cyanobacteria mats. Furthermore, microbial mats inhabited by aerobic methanotrophs may have contributed significantly to the formation of the MnMISS, thus widening the spectrum of environments responsible for marine Mn biometallogenesi
Chromite oxidation by manganese oxides in subseafloor basalts and the presence of putative fossilized microorganisms
Chromite is a mineral with low solubility and is thus resistant to dissolution. The exception is when manganese oxides are available, since they are the only known naturally occurring oxidants for chromite. In the presence of Mn(IV) oxides, Cr(III) will oxidise to Cr(VI), which is more soluble than Cr(III), and thus easier to be removed. Here we report of chromite phenocrysts that are replaced by rhodochrosite (Mn(II) carbonate) in subseafloor basalts from the Koko Seamount, Pacific Ocean, that were drilled and collected during the Ocean Drilling Program (ODP) Leg 197. The mineral succession chromite-rhodochrosite-saponite in the phenocrysts is interpreted as the result of chromite oxidation by manganese oxides. Putative fossilized microorganisms are abundant in the rhodochrosite and we suggest that the oxidation of chromite has been mediated by microbial activity. It has previously been shown in soils and in laboratory experiments that chromium oxidation is indirectly mediated by microbial formation of manganese oxides. Here we suggest a similar process in subseafloor basalts
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