217 research outputs found
Fe/V and Fe/Co (001) superlattices: growth, anisotropy, magnetisation and magnetoresistance
Some physical properties of bcc Fe/V and Fe/Co (001) superlattices are
reviewed. The dependence of the magnetic anisotropy on the in-plane strain
introduced by the lattice mismatch between Fe and V is measured and compared to
a theoretical derivation. The dependence of the magnetic anisotropy (and
saturation magnetisation) on the layer thickness ratio Fe/Co is measured and a
value for the anisotropy of bcc Co is derived from extrapolation. The
interlayer exchange coupling of Fe/V superlattices is studied as a function of
the layer thickness V (constant Fe thickness) and layer thickness of Fe
(constant V thickness). A region of antiferromagnetic coupling and GMR is found
for V thicknesses 12-14 monolayers. However, surprisingly, a 'cutoff' of the
antiferromagnetic coupling and GMR is found when the iron layer thickness
exceeds about 10 monolayers.Comment: Proceedings of the International Symposium on Advanced Magnetic
Materials (ISAMM'02), October 2-4, 2002, Halong Bay, Vietnam. REVTeX style; 4
pages, 5 figure
Effective dynamics of an electrically charged string with a current
Equations of motion for an electrically charged string with a current in an
external electromagnetic field with regard to the first correction due to the
self-action are derived. It is shown that the reparametrization invariance of
the free action of the string imposes constraints on the possible form of the
current. The effective equations of motion are obtained for an absolutely
elastic charged string in the form of a ring (circle). Equations for the
external electromagnetic fields that admit stationary states of such a ring are
revealed. Solutions to the effective equations of motion of an absolutely
elastic charged ring in the absence of external fields as well as in an
external uniform magnetic field are obtained. In the latter case, the frequency
at which one can observe radiation emitted by the ring is evaluated. A model of
an absolutely nonstretchable charged string with a current is proposed. The
effective equations of motion are derived within this model, and a class of
solutions to these equations is found.Comment: 14 pages, 3 figures, format changed, minor change
Prospectus, February 23, 2000
https://spark.parkland.edu/prospectus_2000/1006/thumbnail.jp
Legionella Eukaryotic-Like Type IV Substrates Interfere with Organelle Trafficking
Legionella pneumophila, the causative agent of Legionnaires' disease, evades phago-lysosome fusion in mammalian and protozoan hosts to create a suitable niche for intracellular replication. To modulate vesicle trafficking pathways, L. pneumophila translocates effector proteins into eukaryotic cells through a Type IVB macro-molecular transport system called the Icm-Dot system. In this study, we employed a fluorescence-based translocation assay to show that 33 previously identified Legionella eukaryotic-like genes (leg) encode substrates of the Icm-Dot secretion system. To assess which of these proteins may contribute to the disruption of vesicle trafficking, we expressed each gene in yeast and looked for phenotypes related to vacuolar protein sorting. We found that LegC3-GFP and LegC7/YlfA-GFP caused the mis-secretion of CPY-Invertase, a fusion protein normally restricted to the yeast vacuole. We also found that LegC7/YlfA-GFP and its paralog LegC2/YlfB-GFP formed large structures around the yeast vacuole while LegC3-GFP localized to the plasma membrane and a fragmented vacuole. In mammalian cells, LegC2/YlfB-GFP and LegC7/YlfA-GFP were found within large structures that co-localized with anti-KDEL antibodies but excluded the lysosomal marker LAMP-1, similar to what is observed in Legionella-containing vacuoles. LegC3-GFP, in contrast, was observed as smaller structures which had no obvious co-localization with KDEL or LAMP-1. Finally, LegC3-GFP caused the accumulation of many endosome-like structures containing undigested material when expressed in the protozoan host Dictyostelium discoideum. Our results demonstrate that multiple Leg proteins are Icm/Dot-dependent substrates and that LegC3, LegC7/YlfA, and LegC2/YlfB may contribute to the intracellular trafficking of L. pneumophila by interfering with highly conserved pathways that modulate vesicle maturation
Higher Spin Gauge Theory and Holography: The Three-Point Functions
In this paper we calculate the tree level three-point functions of Vasiliev's
higher spin gauge theory in AdS4 and find agreement with the correlators of the
free field theory of N massless scalars in three dimensions in the O(N) singlet
sector. This provides substantial evidence that Vasiliev theory is dual to the
free field theory, thus verifying a conjecture of Klebanov and Polyakov. We
also find agreement with the critical O(N) vector model, when the bulk scalar
field is subject to the alternative boundary condition such that its dual
operator has classical dimension 2.Comment: 90 pages, 5 figures; v4, minor changes in the introductio
Towards a tensionless string field theory for the N=(2,0) CFT in d=6
We describe progress in using the field theory of tensionless strings to
arrive at a Lagrangian for the six-dimensional conformal
theory. We construct the free part of the theory and propose an ansatz for the
cubic vertex in light-cone superspace. By requiring closure of the
supersymmetry algebra, we fix the cubic vertex up to two parameters.Comment: 46 pages, 2 figures. V2: references added; minor changes and
improvement
Measurements of knee rotation-reliability of an external device in vivo
<p>Abstract</p> <p>Background</p> <p>Knee rotation plays an important part in knee kinematics during weight-bearing activities. An external device for measuring knee rotation (the Rottometer) has previously been evaluated for validity by simultaneous measurements of skeletal movements with Roentgen Stereometric Analysis (RSA). The aim of this study was to investigate the reliability of the device.</p> <p>Method</p> <p>The within-day and test-retest reliability as well as intertester reliability of the device in vivo was calculated. Torques of 3, 6 and 9 Nm and the examiner's apprehension of end-feel were used at 90°, 60° and 30° of knee flexion. Intraclass Correlation Coefficient <sub>2,1 </sub>(ICC <sub>2,1</sub>), 95% confidence interval (CI) of ICC and 95% CI between test trials and examiners were used as statistical tests.</p> <p>Result</p> <p>ICC<sub>2,1 </sub>ranged from 0.50 to 0.94 at all three flexion angles at 6 and 9 Nm as well as end-feel, and from 0.22 to 0.75 at 3 Nm applied torque.</p> <p>Conclusion</p> <p>The Rottometer was a reliable measurement instrument concerning knee rotation at the three different flexion angles (90°, 60° and 30°) with 6 and 9 Nm applied torques as well as the examiner's apprehension of end-feel. Three Nm was not a reliable torque. The most reliable measurements were made at 9 Nm applied torque.</p
Salmonella Typhimurium Type III Secretion Effectors Stimulate Innate Immune Responses in Cultured Epithelial Cells
Recognition of conserved bacterial products by innate immune receptors leads to inflammatory responses that control pathogen spread but that can also result in pathology. Intestinal epithelial cells are exposed to bacterial products and therefore must prevent signaling through innate immune receptors to avoid pathology. However, enteric pathogens are able to stimulate intestinal inflammation. We show here that the enteric pathogen Salmonella Typhimurium can stimulate innate immune responses in cultured epithelial cells by mechanisms that do not involve receptors of the innate immune system. Instead, S. Typhimurium stimulates these responses by delivering through its type III secretion system the bacterial effector proteins SopE, SopE2, and SopB, which in a redundant fashion stimulate Rho-family GTPases leading to the activation of mitogen-activated protein (MAP) kinase and NF-κB signaling. These observations have implications for the understanding of the mechanisms by which Salmonella Typhimurium induces intestinal inflammation as well as other intestinal inflammatory pathologies
Supersymmetric string model with 30 kappa--symmetries in an extended D=11 superspace and 30/ 32 BPS states
A supersymmetric string model in the D=11 superspace maximally extended by
antisymmetric tensor bosonic coordinates, , is proposed. It
possesses 30 -symmetries and 32 target space supersymmetries. The usual
preserved supersymmetry--symmetry correspondence suggests that it
describes the excitations of a BPS state preserving all but two
supersymmetries. The model can also be formulated in any superspace, n=32 corresponding to D=11. It may also be treated as a
`higher--spin generalization' of the usual Green--Schwarz superstring. Although
the global symmetry of the model is a generalization of the super--Poincar\'e
group, , it may be
formulated in terms of constrained OSp(2n|1) orthosymplectic supertwistors. We
work out this supertwistor realization and its Hamiltonian dynamics.
We also give the supersymmetric p-brane generalization of the model. In
particular, the supersymmetric membrane model describes
excitations of a 30/32 BPS state, as the supersymmetric
string does, while the supersymmetric 3-brane and 5-brane correspond,
respectively, to 28/32 and 24/32 BPS states.Comment: 23 pages, RevTex4. V2: minor corrections in title and terminology,
some references and comments adde
Superhard Phases of Simple Substances and Binary Compounds of the B-C-N-O System: from Diamond to the Latest Results (a Review)
The basic known and hypothetic one- and two-element phases of the B-C-N-O
system (both superhard phases having diamond and boron structures and
precursors to synthesize them) are described. The attention has been given to
the structure, basic mechanical properties, and methods to identify and
characterize the materials. For some phases that have been recently described
in the literature the synthesis conditions at high pressures and temperatures
are indicated.Comment: Review on superhard B-C-N-O phase
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