Actividades de tiempo libre y el bienestar espiritual

En esta investigación se analiza la estructura factorial de la Escala de Funciones Espirituales de las actividades de tiempo libre/pasatiempos (Spiritual Functions of Leisure Scale), en una muestra de 202 adultos pertenecientes a los estados de Nuevo León y Yucatán, México, con una edad media de 28 años (DE=9.57). Su validez convergente fue obtenida mediante las escalas de Espiritualidad y Creencias sobre las actividades del tiempo libre (LCBS-M). Ambas escalas, de Espiritualidad y LCBS-M, dieron evidencia de validez convergente. Tras un análisis de competencia de modelos, se logró una estructura factorial similar al modelo original. Este modelo incluye las mismas tres dimensiones y 20 ítems; dos ítems menos al modelo original. Los resultados revelaron que la adaptación mexicana mantuvo un adecuado grado de confiabilidad en la escala general. Abstract This research analyzes the factorial structure of the Leisure Coping Belief Scale (LCBS-M) in a sample of 202 adults belonging to the states of Nuevo León and Yucatan, Mexico, with an average age of 28 years (DE = 9.57). Its convergent validity was obtained through the Spirituality and Leisure Coping Belief Scales (LCBS-M) about their leisure activities. Both scales, the Spirituality and the LCBS-M, gave evidence of convergent validity. Following an analysis of competition of models, a factoria structure similar to the original model was obtained. This model includes the same three dimensions and 20 items; two items less than the original model. The results revealed that the Mexican adaptation maintained an adequate degree of reliability on a general scale

Bienestar y familia, una mirada desde la psicología positiva

Este libro está dirigido a estudiantes y profesionales en psicología y áreas afines, como enfermería, trabajo social o educación, y a los interesados en personalidad positiva. Cada capítulo se presenta de manera sencilla y con una estructura didáctica, pero sin perder rigor científico y calidad de la revisión, con el fin de facilitar el acceso a la información sobre bienestar individual, familiar y social de una forma accesible para adentrarnos al estudio de temas de psicología positiva. Dadas las temáticas, se consideró pertinente dividir este libro en dos secciones: I. Psicología positiva y bienestar. II. Bienestar individual y familiar.Universidad Autónoma del Estado de México y Ediciones y Gráficos Eón, S.A. de C.V

E6 Oncoproteins from High-Risk Human Papillomavirus Induce Mitochondrial Metabolism in a Head and Neck Squamous Cell Carcinoma Model

Head and neck squamous cell carcinoma (HNSCC) cells that are positive for human papillomavirus (HPV+) favor mitochondrial metabolism rather than glucose metabolism. However, the involvement of mitochondrial metabolism in HNSCC HPV+ cells is still unknown. The aim of this work was to evaluate the role of E6 oncoproteins from HPV16 and HPV18 in the mitochondrial metabolism in an HNSCC model. We found that E6 from both viral types abates the phosphorylation of protein kinase B-serine 473 (pAkt), which is associated with a shift in mitochondrial metabolism. E6 oncoproteins increased the levels of protein subunits of mitochondrial complexes (I to IV), as well as the ATP synthase and the protein levels of the voltage dependent anion channel (VDAC). Although E6 proteins increased the basal and leak respiration, the ATP-linked respiration was not affected, which resulted in mitochondrial decoupling. This increase in leak respiration was associated to the induction of oxidative stress (OS) in cells expressing E6, as it was observed by the fall in the glutathione/glutathione disulfide (GSH/GSSG) rate and the increase in reactive oxygen species (ROS), carbonylated proteins, and DNA damage. Taken together, our results suggest that E6 oncoproteins from HPV16 and HPV18 are inducers of mitochondrial metabolism

Word Association Norms for Healthy Older Adults

database of word association and sociodemographic data of older adult