POLITICAL INSTITUTE OF THE STATE IN THE CONTEXT OF THE HISTORICAL AND TYPOLOGICAL ANALYSIS

Abstract. Article is devoted to problems of structuring state created history taking into account variety social, political, forms, various speed of a political genesis. Problems of allocation of development stages of the political organizations (statehood) taking into account uncertainty of the general units of the analysis, terms and concepts of rather various paradigms of structuring and a periodization of history are considered. It is shown that the decisive force causing transformation of all other public sectors is growth, distribution and deduction of a dominant position of the most effective in the conditions of this period of a political regime.Key words: historical, typological analysis, potestarny structures, historicism, Kondratiyev’s paradigm,political regime

Instituto político del Estado en el contexto del análisis histórico y tipológico

The article is devoted to problems of structuring state created history taking into account a variety of social, political, forms, various speeds of political genesis. Problems of allocation of development stages of the political organizations (statehood) taking into account uncertainty of the general units of the analysis, terms, and concepts of rather various paradigms of structuring and periodization of history are considered. It is shown that the decisive force causing the transformation of all other public sectors is growth, distribution, and deduction of a dominant position of the most effective in the conditions of this period of a political regime.El artículo está dedicado a los problemas de estructuración de la historia creada por el estado teniendo en cuenta una variedad de formas sociales, políticas, diversas velocidades de génesis política. Se consideran los problemas de asignación de etapas de desarrollo de las organizaciones políticas (estatismo) teniendo en cuenta la incertidumbre de las unidades generales del análisis, los términos y los conceptos de varios paradigmas de estructuración y periodización de la historia. Se muestra que la fuerza decisiva que causa la transformación de todos los demás sectores públicos es el crecimiento, la distribución y la deducción de una posición dominante de los más efectivos en las condiciones de este período de un régimen político

Novel degradable photocatalysts for wastewater treatment

The weakening of the manmade load on the environment has become a global goal of humanity. The accumulation of toxic substances in effl uents can increase the acceleration of pollution of the planet’s watersheds, resulting in biota pollution. To solve this problem, it is necessary to create photocatalysts that cause self-excitation under the ignition of light. Also, important parameters of photocatalysts are simple synthesis and low cost. This article demonstrates a one-step approach to the synthesis of carbon nanostructures (CNS) with photocatalytic activity. For this purpose, the “green chemistry ” method is used – hydrothermal treatment of various polysaccharides (sodium dextran sulfate (SDS), starch, pectin), which opens up the possibility of recycling products. A comprehensive study of the properties of the synthesized CNS has been carried out. To study the optical properties of CNS, absorption and luminescence spectroscopy, and IR spectroscopy, have been used. The CNS obtained have been successfully used in the processes of photocatalytic destruction of a model of the organic dye tartrazine, which is widely used in the fi ber and textile industries. The eff ect of lyophilization on the photocatalytic properties of СNS has been studied, and cytotoxicity has been evaluated

Intraoperative electroencephalogram patterns as predictors of postoperative delirium in older patients: a systematic review and meta-analysis

BackgroundPostoperative delirium (POD) significantly affects patient outcomes after surgery, leading to increased morbidity, extended hospital stays, and potential long-term cognitive decline. This study assessed the predictive value of intraoperative electroencephalography (EEG) patterns for POD in adults.MethodsThis systematic review and meta-analysis followed the PRISMA and Cochrane Handbook guidelines. A thorough literature search was conducted using PubMed, Medline, and CENTRAL databases focusing on intraoperative native EEG signal analysis in adult patients. The primary outcome was the relationship between the burst suppression EEG pattern and POD development.ResultsFrom the initial 435 articles identified, 19 studies with a total of 7,229 patients were included in the systematic review, with 10 included in the meta-analysis (3,705 patients). In patients exhibiting burst suppression, the POD incidence was 22.1% vs. 13.4% in those without this EEG pattern (p=0.015). Furthermore, an extended burst suppression duration associated with a higher likelihood of POD occurrence (p = 0.016). Interestingly, the burst suppression ratio showed no significant association with POD.ConclusionsThis study revealed a 41% increase in the relative risk of developing POD in cases where a burst suppression pattern was present. These results underscore the clinical relevance of intraoperative EEG monitoring in predicting POD in older patients, suggesting its potential role in preventive strategies.Systematic Review RegistrationThis study was registered on International Platform for Registered Protocols for Systematic Reviews and Meta-Analyses: INPLASY202420001, https://doi.org/10.37766/inplasy2024.2.0001

Instituto político del Estado en el contexto del análisis histórico y tipológico

The article is devoted to problems of structuring state created history taking into account a variety of social, political, forms, various speeds of political genesis. Problems of allocation of development stages of the political organizations (statehood) taking into account uncertainty of the general units of the analysis, terms, and concepts of rather various paradigms of structuring and periodization of history are considered. It is shown that the decisive force causing the transformation of all other public sectors is growth, distribution, and deduction of a dominant position of the most effective in the conditions of this period of a political regime.El artículo está dedicado a los problemas de estructuración de la historia creada por el estado teniendo en cuenta una variedad de formas sociales, políticas, diversas velocidades de génesis política. Se consideran los problemas de asignación de etapas de desarrollo de las organizaciones políticas (estatismo) teniendo en cuenta la incertidumbre de las unidades generales del análisis, los términos y los conceptos de varios paradigmas de estructuración y periodización de la historia. Se muestra que la fuerza decisiva que causa la transformación de todos los demás sectores públicos es el crecimiento, la distribución y la deducción de una posición dominante de los más efectivos en las condiciones de este período de un régimen político

Political Institute of the State in the Context of the Historical and Typological Analysis

The article is devoted to problems of structuring state created history taking into account a variety of social, political, forms, various speeds of political genesis. Problems of allocation of development stages of the political organizations (statehood) taking into account uncertainty of the general units of the analysis, terms, and concepts of rather various paradigms of structuring and periodization of history are considered. It is shown that the decisive force causing the transformation of all other public sectors is growth, distribution, and deduction of a dominant position of the most effective in the conditions of this period of a political regime

GC-MS with Headspace Extraction for Non-Invasive Diagnostics of IBD Dynamics in a Model of DSS-Induced Colitis in Rats

Inflammatory bowel diseases are extremely common throughout the world. However, in most cases, it is asymptomatic at the initial stage. Therefore, it is important to develop non-invasive diagnostic methods that allow identification of the IBD risks in a timely manner. It is well known that gastrointestinal microbiota secrete volatile compounds (VOCs) and their composition may change in IBD. We propose a non-invasive method to identify the dynamics of IBD development in the acute and remission stage at the level of VOCs in model of dextran sulfate sodium (DSS) with chemically induced colitis measured by headspace GC/MS (HS GC/MS). Methods: VOCs profile was identified using a headspace GC/MS (HS GC/MS). GC/MS data were processed using MetaboAnalyst 5.0 and GraphPad Prism 8.0.1 software. The disease activity index (DAI) and histological method were used to assess intestinal inflammation. The peak of intestinal inflammation activity was reached on day 7, according to the disease activity index. Histological examination data showed changes in the intestine due to different stages of inflammation. As the acute inflammation stage was reached, the metabolomic profile also underwent changes, especially at the short-fatty acids level. A higher relative amounts of acetic acid (p value p value p value p value = 0.053) were observed in DSS7 group on day 7 compared to the control group. In remission stage, disease activity indexes decreased, and the histological picture also improved. But metabolome changes continued despite the withdrawal of the DSS examination. A lower relative amounts of propanoic acid (p value p value p value p value < 0.0005) relative amounts were observed in the DSS14 group compared to the control group on day 14. A model of DSS-induced colitis in rats was successfully implemented for metabolomic assessment of different stages of inflammation. We demonstrated that the ratios of volatile compounds change in response to DSS before the appearance of standard signs of inflammation, determined by DAI and histological examination. Changes in the volatile metabolome persisted even after visual intestine repair and it confirms the high sensitivity of the microbiota to the damaging effects of DSS. The use of HS GC/MS may be an important addition to existing methods for assessing inflammation at early stages

Public Expenditure on Education and Health in Russian Federation Before and During the Global Crisis

This paper explores the effects that the global financial crisis of 2008 - 2010 had on the funding and performance of the healthcare and education sectors in the Russian Federation (RF). Both education and healthcare expenditures increased in terms of total general government (GG) spending relative to GDP, partly as a result of reduced GDP. The crisis induced further centralization by increasing both the role of the federal budget in funding social services and the dependence of regions on federal transfers, but it did not result in enhanced resource allocation or more effective public spending. By revealing the inefficiencies that accumulated in education and healthcare financing and management throughout the 2000s, the crisis exposed acute funding shortages in contrast to the government's stated goals and an urgent need for reform in these sectors. The impact of the financial crisis on the delivery of education and health services appeared to be delayed and was mitigated by the resources accumulated during the pre-crisis boom. The paper concludes with several recommendations for the RF public service sector concerning improvements in the inter-governmental transfer system through increasing transparency and introducing performance-oriented budgeting