Psychological Self-Sufficiency and Financial Literacy Among Low-Income Participants: An Empowerment-Based Approach to Financial Capability

Building on theory and research in financial capability, this study enhances a financial capability model by integrating psychological self-sufficiency (PSS) theory as part of the financial literacy component. Using PSS, a concept from workforce development literature, this study investigates the extent to which an empowerment-based PSS process in targeting financial goals is associated with financial literacy. Path analyses were conducted using a sample of 187 low-income individuals from a large social service agency in Chicago. Findings suggest that perceived financial barriers and financial hope—the two targets of PSS interventions—are associated with financial attitude and behavior, controlling for other demographic variables. These findings can guide policy makers and service providers to build in PSS process-based financial literacy components in vocational and adult education and training as a more human-centered approach to workforce development

VEGFR2 but not VEGFR3 governs integrity and remodeling of thyroid angiofollicular unit in normal state and during goitrogenesis

Thyroid gland vasculature has a distinguishable characteristic of endothelial fenestrae, a critical component for proper molecular transport. However, the signaling pathway that critically governs the maintenance of thyroid vascular integrity, including endothelial fenestrae, is poorly understood. Here, we found profound and distinct expression of follicular epithelial VEGF-A and vascular VEGFR2 that were precisely regulated by circulating thyrotropin, while there were no meaningful expression of angiopoietin-Tie2 system in the thyroid gland. Our genetic depletion experiments revealed that VEGFR2, but not VEGFR3, is indispensable for maintenance of thyroid vascular integrity. Notably, blockade of VEGF-A or VEGFR2 not only abrogated vascular remodeling but also inhibited follicular hypertrophy, which led to the reduction of thyroid weights during goitrogenesis. Importantly, VEGFR2 blockade alone was sufficient to cause a reduction of endothelial fenestrae with decreases in thyrotropin-responsive genes in goitrogen-fed thyroids. Collectively, these findings establish follicular VEGF-Avascular VEGFR2 axis as a main regulator for thyrotropindependent thyroid angiofollicular remodeling and goitrogenesis.Peer reviewe

Distinct fibroblast subsets regulate lacteal integrity through YAP/TAZ-induced VEGF-C in intestinal villi

Emerging evidence suggests that intestinal stromal cells (IntSCs) play essential roles in maintaining intestinal homeostasis. However, the extent of heterogeneity within the villi stromal compartment and how IntSCs regulate the structure and function of specialized intestinal lymphatic capillary called lacteal remain elusive. Here we show that selective hyperactivation or depletion of YAP/TAZ in PDGFR beta(+) IntSCs leads to lacteal sprouting or regression with junctional disintegration and impaired dietary fat uptake. Indeed, mechanical or osmotic stress regulates IntSC secretion of VEGF-C mediated by YAP/TAZ. Single-cell RNA sequencing delineated novel subtypes of villi fibroblasts that upregulate Vegfc upon YAP/TAZ activation. These populations of fibroblasts were distributed in proximity to lacteal, suggesting that they constitute a peri-lacteal microenvironment. Our findings demonstrate the heterogeneity of IntSCs and reveal that distinct subsets of villi fibroblasts regulate lacteal integrity through YAP/TAZ-induced VEGF-C secretion, providing new insights into the dynamic regulatory mechanisms behind lymphangiogenesis and lymphatic remodeling.Peer reviewe

Emergence of liquid following laser melting of gold thin films

X-ray structural science is undergoing a revolution driven by the emergence of X-ray Free-electron Laser (XFEL) facilities. The structures of crystalline solids can now be studied on the picosecond time scale relevant to phonons, atomic vibrations which travel at acoustic velocities. In the work presented here, X-ray diffuse scattering is employed to characterize the time dependence of the liquid phase emerging from femtosecond laser-induced melting of polycrystalline gold thin films using an XFEL. In a previous analysis of Bragg peak profiles, we showed the supersonic disappearance of the solid phase and presented a model of pumped hot electrons carrying energy from the gold surface to scatter at internal grain boundaries. This generates melt fronts propagating relatively slowly into the crystal grains. By conversion of diffuse scattering to a partial X-ray pair distribution function, we demonstrate that it has the characteristic shape obtained by Fourier transformation of the measured F(Q). The diffuse signal fraction increases with a characteristic rise-time of 13 ps, roughly independent of the incident pump fluence and consequent final liquid fraction. This suggests the role of further melt-front nucleation processes beyond grain boundaries

CEERS: Diversity of Lyman-Alpha Emitters during the Epoch of Reionization

We analyze rest-frame ultraviolet to optical spectra of three $z\simeq7.47$ - $7.75$ galaxies whose Ly$\alpha$-emission lines were previously detected with Keck/MOSFIRE observations, using the JWST/NIRSpec observations from the Cosmic Evolution Early Release Science (CEERS) survey. From NIRSpec data, we confirm the systemic redshifts of these Ly$\alpha$ emitters, and emission-line ratio diagnostics indicate these galaxies were highly ionized and metal poor. We investigate Ly$\alpha$ line properties, including the line flux, velocity offset, and spatial extension. For the one galaxy where we have both NIRSpec and MOSFIRE measurements, we find a significant offset in their flux measurements ($\sim5\times$ greater in MOSFIRE) and a marginal difference in the velocity shifts. The simplest interpretation is that the Ly$\alpha$ emission is extended and not entirely encompassed by the NIRSpec slit. The cross-dispersion profiles in NIRSpec reveal that Ly$\alpha$ in one galaxy is significantly more extended than the non-resonant emission lines. We also compute the expected sizes of ionized bubbles that can be generated by the Ly$\alpha$ sources, discussing viable scenarios for the creation of sizable ionized bubbles ($>$1 physical Mpc). The source with the highest-ionization condition is possibly capable of ionizing its own bubble, while the other two do not appear to be capable of ionizing such a large region, requiring additional sources of ionizing photons. Therefore, the fact that we detect Ly$\alpha$ from these galaxies suggests diverse scenarios on escape of Ly$\alpha$ during the epoch of reionization. High spectral resolution spectra with JWST/NIRSpec will be extremely useful for constraining the physics of patchy reionization.Comment: Submitted to ApJ (18 pages, 7 figures, 2 tables

Penilaian Kinerja Keuangan Koperasi di Kabupaten Pelalawan

This paper describe development and financial performance of cooperative in District Pelalawan among 2007 - 2008. Studies on primary and secondary cooperative in 12 sub-districts. Method in this stady use performance measuring of productivity, efficiency, growth, liquidity, and solvability of cooperative. Productivity of cooperative in Pelalawan was highly but efficiency still low. Profit and income were highly, even liquidity of cooperative very high, and solvability was good