Flipped Classroom, Teaching Solution for Writing Class

The research was designed to investigate the result of a study comparing two English writing classes of  Indraprasta PGRI University student in  the sixth semester of 2015/2016. There were thirty students for each class chosen randomly. The research was conducted from March to July 2016. One class was taught in a traditional way and the other using the flipped method. A test is given at the end of the treatment to detect the level of student understanding. Results of post test are  compared using t-test to gauge whether the method of "Flipped Classroom" has effect on student understanding. This research is a field research with posttest-only control group design method. The theoryused to determine the ability of the students is a statistical theory  by Sudjana, cohesion were analyzed using the theory of Cohesion in English by Halliday and Hassan. Factors affect the ability to write theory by Harmer. The study resulted tcount 2,256 and ttable 1.67 at ? = 0.05 level. So tcount> ttable, so that Ho refused mean significant. It can be concluded also that there is a positive and significant influence

DEVELOPMENT AND IMPROVEMENT OF THE VALUE’S HAND CRAFTS THROUGH ENTREPRENEURS MANAGEMENT TO THE STUDENT OF VOCATIONAL HIGH SCHOOL IN CIBINONG DISTRICT – BOGOR

The target of this community service activity is Vocational High School (SMK) in Cibinong and Citeureup Sub - Bogor Regency. Some Participants involved are students of  11th, 12th, and 13th graders. Based on their potential, vocational school students have a tendency in entrepreneurial program of UMKM which is very varied, especially in creative industry sector. Through this activity will form the soul of a new generation of entrepreneurs who have good character and have the ability to compete for self-competence in the era of government that promote entrepreneurship programs in the face of Asean Free Trade Association (AFTA) so as to be beneficial to prospective entrepreneurs and able to sustain the economy individually and national. This activity is conducted by visiting and conducting workshop on entrepreneurship and business management for students who gathered in the hall of each Vocational High School in Cibinong sub-district, Bogor regency. Implementation of community service activities has been successfully implemented with percentage to the planning, process, the result is 91,3%; 97.5%, and 97.5% in very good category. And it can be concluded that the responses of the participants to the implementation of the workshop entrepreneurship in SMKN 01 PGRI Cibinong and SMK Bina Harapan Citeureup is very good. This is evident from the attendance indicators of participants reached 97% of the number of participants who targeted its attendance

Upaya Peningkatan Usaha Masyarakat Melalui Pengurusan Perizinan Usaha dan Merek

Kegiatan Penyuluhan Perizinan Usaha dan Merek ini dilaksanakan dengan tujuan sebagai berikut: 1) memberikan pengetahuan dan menumbuhkan kesadaran mengenai pentingnya memiliki perizinan usaha; 2) memberikan pemahaman bahwa mengurus perizinan usaha sangat mudah dan praktis; dan 3) memberikan pemahaman tentang tata cara mengurus perizinan usaha dan pendaftaran merek. Hasil yang diperoleh penyuluhan perizinan usaha dan merek disimpulkan berhasil karena persepsi peserta menganggap penting kegiatan ini bahwa masyarakat sasaran memiliki pemahaman tentang perizinan usaha dan merek yang meningkat sebesar 90% dari yang diharapkan. Sedangkan tingkat tertinggi persepsi terhadap pentingnya memiliki izin usaha dan merek dilakukan demi citra dan kredibilitas usaha dan produk yang legal/formal sebesar 89%

A method to define the priority for maintenance and repair works of Italian motorway tunnels

The construction of motorways in Italy dates back to 1921 and still lasts today. Along them there is a large number of tunnels, many of which have been in service for more than 50 years and have experienced various levels of decay due to aging. An extensive assessment and inspection plan is taking place finalized to highlight situations where maintenance and repair works are needed to guarantee the continuation of service in safe conditions and functionality. Due to the number of tunnels, the need arises to classify them and define priorities for intervention on the basis of a first assessment and of a robust and scientific-based tool to orientate the investments. This paper describes the methodology that was developed by the Authors for this purpose, assessing the attention level of every tunnel. The method relies on a quantitative approach that allows quantifying the risk based on five risk factors composed of a number of relevant parameters. Their relative interaction, which guided the scores assigned to each parameter, was assessed by applying the Rock Engineering System [2]. A number of examples of existing tunnels are shown to illustrate the application of the method and to draw conclusions about its validity and reliability

Fluctuations and differential contraction during regeneration of Hydra vulgaris tissue toroids

We studied regenerating bilayered tissue toroids dissected from Hydra vulgaris polyps and relate our macroscopic observations to the dynamics of force-generating mesoscopic cytoskeletal structures. Tissue fragments undergo a specific toroid-spheroid folding process leading to complete regeneration towards a new organism. The time scale of folding is too fast for biochemical signalling or morphogenetic gradients which forced us to assume purely mechanical self-organization. The initial pattern selection dynamics was studied by embedding toroids into hydro-gels allowing us to observe the deformation modes over longer periods of time. We found increasing mechanical fluctuations which break the toroidal symmetry and discuss the evolution of their power spectra for various gel stiffnesses. Our observations are related to single cell studies which explain the mechanical feasibility of the folding process. In addition, we observed switching of cells from a tissue bound to a migrating state after folding failure as well as in tissue injury. We found a supra-cellular actin ring assembled along the toroid's inner edge. Its contraction can lead to the observed folding dynamics as we could confirm by finite element simulations. This actin ring in the inner cell layer is assembled by myosin- driven length fluctuations of supra-cellular {\alpha}-actin structures (myonemes) in the outer cell-layer.Comment: 19 pages and 8 figures, submitted to New Journal of Physic

3D Voronoi Tessellation for the Study of Mechanical Behavior of Rocks at Different Scales

Numerical investigation of crack damage development and microfracturing in brittle rocks is a widely studied topic, given the number of applications involved. In the framework of the Discrete Element Method (DEM) formulation, the grain-based distinct element model with random polygonal blocks can represent an alternative to the Bonded-Particle Model (BPM) based on particles. Recently, a new engine called Neper has been made available for generating 3D Voronoi grains. The aim of this study is to investigate the applicability of a Neper-based 3D Voronoi tessellation technique for the simulation of the mechanical macro response of rocks. Simulation of unconfined compression tests on synthetic specimens is conducted and a calibration procedure tested. The issue related to scale effects is also addressed, with an application to the case study of a deep geothermal reservoir

Chemotherapy-Response Monitoring of Breast Cancer Patients Using Quantitative Ultrasound-Based Intra-Tumour Heterogeneities

© 2017 The Author(s). Anti-cancer therapies including chemotherapy aim to induce tumour cell death. Cell death introduces alterations in cell morphology and tissue micro-structures that cause measurable changes in tissue echogenicity. This study investigated the effectiveness of quantitative ultrasound (QUS) parametric imaging to characterize intra-tumour heterogeneity and monitor the pathological response of breast cancer to chemotherapy in a large cohort of patients (n = 100). Results demonstrated that QUS imaging can non-invasively monitor pathological response and outcome of breast cancer patients to chemotherapy early following treatment initiation. Specifically, QUS biomarkers quantifying spatial heterogeneities in size, concentration and spacing of acoustic scatterers could predict treatment responses of patients with cross-validated accuracies of 82 ± 0.7%, 86 ± 0.7% and 85 ± 0.9% and areas under the receiver operating characteristic (ROC) curve of 0.75 ± 0.1, 0.80 ± 0.1 and 0.89 ± 0.1 at 1, 4 and 8 weeks after the start of treatment, respectively. The patients classified as responders and non-responders using QUS biomarkers demonstrated significantly different survivals, in good agreement with clinical and pathological endpoints. The results form a basis for using early predictive information on survival-linked patient response to facilitate adapting standard anti-cancer treatments on an individual patient basis

A coarse-to-fine approach to prostate boundary segmentation in ultrasound images

BACKGROUND: In this paper a novel method for prostate segmentation in transrectal ultrasound images is presented. METHODS: A segmentation procedure consisting of four main stages is proposed. In the first stage, a locally adaptive contrast enhancement method is used to generate a well-contrasted image. In the second stage, this enhanced image is thresholded to extract an area containing the prostate (or large portions of it). Morphological operators are then applied to obtain a point inside of this area. Afterwards, a Kalman estimator is employed to distinguish the boundary from irrelevant parts (usually caused by shadow) and generate a coarsely segmented version of the prostate. In the third stage, dilation and erosion operators are applied to extract outer and inner boundaries from the coarsely estimated version. Consequently, fuzzy membership functions describing regional and gray-level information are employed to selectively enhance the contrast within the prostate region. In the last stage, the prostate boundary is extracted using strong edges obtained from selectively enhanced image and information from the vicinity of the coarse estimation. RESULTS: A total average similarity of 98.76%(± 0.68) with gold standards was achieved. CONCLUSION: The proposed approach represents a robust and accurate approach to prostate segmentation