Pairing collectivity in medium-mass neutron-rich nuclei near drip-line

We look for collective excitations originating from the strong surface pairing in unstable nuclei near the neutron drip-line. The soft dipole excitation is such a pairing mode as it exhibits a character of core-vs-dineutron motion. Possibility of the hydrodynamic phonon mode (the Anderson-Bogoliubov mode) is also discussed.Comment: 9 pages, a talk presented at Collective Motion in Nuclei under Extreme Conditions (COMEX2), June 20-23, 2006, St. Goar, German

A comparison study for two fuzzy-based systems: improving reliability and security of JXTA-overlay P2P platform

This is a copy of the author's final draft version of an article published in the journal Soft computing.The reliability of peers is very important for safe communication in peer-to-peer (P2P) systems. The reliability of a peer can be evaluated based on the reputation and interactions with other peers to provide different services. However, for deciding the peer reliability there are needed many parameters, which make the problem NP-hard. In this paper, we present two fuzzy-based systems (called FBRS1 and FBRS2) to improve the reliability of JXTA-overlay P2P platform. In FBRS1, we considered three input parameters: number of interactions (NI), security (S), packet loss (PL) to decide the peer reliability (PR). In FBRS2, we considered four input parameters: NI, S, PL and local score to decide the PR. We compare the proposed systems by computer simulations. Comparing the complexity of FBRS1 and FBRS2, the FBRS2 is more complex than FBRS1. However, it also considers the local score, which makes it more reliable than FBRS1.Peer ReviewedPostprint (author's final draft

A GA-based simulation system for WMNs: performance analysis for different WMN architectures considering transmission rate and OLRS protocol

(c) 2016 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other users, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works for resale or redistribution to servers or lists, or reuse of any copyrighted components of this work in other works.In this paper, we evaluate the performance of two WMN architectures considering throughput, delay, jitter and fairness index metrics. For simulations, we used ns-3. We compare the performance for two architectures considering transmission rate and OLSR protocol. The simulation results show that for transmission rate 600 and 1200 [kbps], the throughput of Hybrid WMN is higher than I/B WMN. For transmission rate 600 and 1200 [kbps], the delay and jitter of Hybrid WMN is lower than I/B WMN. For transmission rate 600 and 1200 [kbps], the fairness index of I/B WMN is higher than Hybrid WMN.Peer ReviewedPostprint (author's final draft

Diabetes-Related Ankyrin Repeat Protein (DARP/Ankrd23) Modifies Glucose Homeostasis by Modulating AMPK Activity in Skeletal Muscle.

Skeletal muscle is the major site for glucose disposal, the impairment of which closely associates with the glucose intolerance in diabetic patients. Diabetes-related ankyrin repeat protein (DARP/Ankrd23) is a member of muscle ankyrin repeat proteins, whose expression is enhanced in the skeletal muscle under diabetic conditions; however, its role in energy metabolism remains poorly understood. Here we report a novel role of DARP in the regulation of glucose homeostasis through modulating AMP-activated protein kinase (AMPK) activity. DARP is highly preferentially expressed in skeletal muscle, and its expression was substantially upregulated during myotube differentiation of C2C12 myoblasts. Interestingly, DARP-/- mice demonstrated better glucose tolerance despite similar body weight, while their insulin sensitivity did not differ from that in wildtype mice. We found that phosphorylation of AMPK, which mediates insulin-independent glucose uptake, in skeletal muscle was significantly enhanced in DARP-/- mice compared to that in wildtype mice. Gene silencing of DARP in C2C12 myotubes enhanced AMPK phosphorylation, whereas overexpression of DARP in C2C12 myoblasts reduced it. Moreover, DARP-silencing increased glucose uptake and oxidation in myotubes, which was abrogated by the treatment with AICAR, an AMPK activator. Of note, improved glucose tolerance in DARP-/- mice was abolished when mice were treated with AICAR. Mechanistically, gene silencing of DARP enhanced protein expression of LKB1 that is a major upstream kinase for AMPK in myotubes in vitro and the skeletal muscle in vivo. Together with the altered expression under diabetic conditions, our data strongly suggest that DARP plays an important role in the regulation of glucose homeostasis under physiological and pathological conditions, and thus DARP is a new therapeutic target for the treatment of diabetes mellitus