IMPROVEMENT OF PHARMACEUTICAL SPECIALISTS DURING THE PERIOD OF REFORMING MEDICINE AND PHARMACY IN UKRAINE

The article describes the need to determine the main directions and priorities of the development of the pharmaceutical industry in Ukraine, which is conditioned by real political and socioeconomic processes. The main element here is the introduction and development of a formular system - a complex of management methods for the application of rational, organizational and cost-effective methods of supplying and using drugs to ensure, in specific conditions, high quality medical care and optimal use of available resources.Key words: pharmaceutical industry, pharmacist, pharmacist, higher education

The project method in teaching future mathematics teachers

This paper deals with the problem of using the project method in teaching future mathematics teachers. The authors showed that one of such technologies is project training, which involves joint learning and cognitive activity of students, having a common goal, agreed ways of working. This paper notes also the need to use project technology, which consists in developing the ability of future teachers to have an analytical, creative thinking; self-acquisition of missing math knowledge from various sources; thinking, based on knowledge of mathematical facts, the laws of science; and ability to work in a team, performing various social role

To the problems of modeling the brain ischemia in small animals

In the review article the problems of modeling cerebral ischemia in small mammals are consecrated. The advantages of experimental studies that are based on the similarity of the blood circulation of the brain in humans and animals are indicated. Classification of experimental models for the study of acute and chronic disorders of cerebral circulation, mechanisms of their development and preclinical approbation of new drugs is given. The authors indicate that all experimental models of brain ischemia can be divided into two groups: to study risk factors and pathophysiological studies of brain ischemia. And in the second case, the models of focal and global ischemia are described. In conclusion, the authors point out the difficulties and shortcomings of certain methods of ischemia reproduction, which await researchers to solve the above problems

Development of the new employment forms in the context of digital transformation of the economy

The article deals with the problems of the formation of new forms of employment under the influence of digitalisation processes and a protracted economic crisis. The purpose of the study is to consider the little-studied aspects of development of the new forms of employment in the conditions of the “fourth industrial revolution” and determine their prospects. The work shows that the spread of new forms of employment in the context of the formation of a new technological order indicates the digital transformation of the economy and at the same time acts as a response to the economic crisis caused by the obsolescence of the industries of the outgoing modes due to the gradual exhaustion of their efficiency, including impact of the recent COVID-19 pandemic. At the same time, the introduction of new elements of employment into the system of social and labor relations does not eliminate the previously existing conflicts of interests of their participants, but ensures a more dynamic development of the labor market and increases the adaptive potential of workers. Particular attention is paid to such forms of work organization as mobile work based on information and communication technologies, work on platforms and sharing of employees’ labor. The authors conduct a comparative analysis of the advantages and disadvantages of these forms of employment based on employers’ and employees’ interests and points of view. Reserves of growth and restrictions on the development of new forms of employment have been identified. Attention is focused on the social and cultural consequences of increased flexibility and mobility of labor relations in the context of the development of new non-standard forms of employment. The results of the study can be used in developing areas for improvement of employment policy in the context of further deployment of digitalisation processes

Integration of theoretical and clinical disciplines teaching as one of factors of medical knowledge efficacy

The article discusses the problem of medical students theoretical knowledge improvement that will significantly improve their clinical knowledge. The main factors that determine medical students’ positive motivation to study are considered. The authors prove that both theoretical and clinical disciplines teaching integration is possible as a result of complex approach to students teaching that will result in students’ knowledge survival on the higher courses. Leading role belongs to the theoretical departments which workers by writing textbooks and manuals, creating teaching multimedia programmes, using exact control and students' knowledge evaluation will provide the necessary motivational component of students’ further teaching on clinical departments. The integrated approach contributes to future profession single picture formation, motivates students to theoretical and clinical disciplines deep study. The future doctors teaching process reforming at Odessa National Medical University General and Clinical Pathological Physiology Department is given as an example.Authors guesses that new methodical methods of working with students in the practical work introduction, the change in the technology of teaching, the modification of the educational process, the approximation of theoretical knowledge to the patient's bed, the greater students interest in the positive end-goal - a correct diagnosis and cure of the patient - will allow to optimize the educational process and improve the quality of students’ training

Исследование параметрических взаимодействий при регулировании ядерного реактора с обратной связью

This article considers the principal theoretical possibility of regulating a nuclear power reactor under changing operating modes conditions when external periodic disturbances take place in conditions of changing the operating mode. By the external periodic perturbation a downward change in the conditions of the heat sink was meant. The magnitude of the changes was preliminarily calculated in such a way that the operating conditions of the power plant did not exceed the boundaries of the safe operation zone of the reactor. In the case of approaching the operation parameters to the critical ones, the heat sink was increased until the working conditions returned to their previous state. In this work the amplitude frequency response of a non-linearly enhanced system in the nuclear power plant operating conditions when non-linearly reacting to external periodic influences has been studied. The external cyclic disturbances effect produced on the reactor that initially existed under stationary operating conditions has been considered. The research was carried out by numerical simulation of the competition between processes occurring in a nuclear power plant and determined by the system’s reaction time and relaxation time while responding to periodic external influences. Calculations of the relaxation time dependence on the fixed frequency-revealing external influence’s temperature are presented. Also, the relaxation time dependence on the frequency of external influence at a fixed temperature for systems with various relaxation periods was calculated. It is determined that when the dependence between system temperature and the external influence time is calculated, there exists a wide range of possible frequency control. To evaluate the behavior of a nuclear power reactor under conditions of operating modes changes, a fundamental physical mathematical model of the reactor’s state under external harmonic influence is presented. It is based on the nonlinear Riccati equation. The external harmonic effect was simulated by changing the heat supply and heat removal conditions near the critical point.Рассмотрена принципиальная теоретическая возможность регулирования ядерного энергетического реактора, находящегося под воздействием внешних периодических возмущений, в условиях изменения режимов работы. Под внешним периодическим возмущением подразумевалось изменение условий теплоотвода в сторону уменьшения. Величина изменений предварительно расcчитывалась таким образом, чтобы условия работы энергетической установки не выходили за границы зоны безопасной работы реактора. В случае приближения параметров работы к критическим теплоотвод увеличивался до момента возвращения условий работы в прежнее состояние. Изучен амплитудный частотный отклик нелинейно обостренной системы в условиях работы ядерной энергетической установки, нелинейно реагирующей на внешние периодические воздействия. Рассмотрено воздействие внешних циклических возмущений на реактор, исходно находящийся в стационарном рабочем состоянии. Проведены исследования путем численного моделирования конкуренции процессов, протекающих в ядерной энергетической установке, которые определяются временем реакции и временем релаксации системы на периодическое внешнее воздействие. Представлены расчеты зависимости времени релаксации от температуры внешнего воздействия при фиксированной частоте, времени релаксации от частоты внешнего воздействия при фиксированной температуре для систем с разным временем релаксации. Определено, что при расчете зависимости температуры системы от времени внешнего воздействия существует широкая зона возможного частотного регулирования. Для оценки поведения ядерного энергетического реактора в условиях изменения режимов работы создана принципиальная физико-математическая модель состояния реактора, находящегося под внешним гармоническим воздействием, на основе нелинейного уравнения Риккати. Внешнее гармоническое воздействие моделировалось путем изменения условий теплоподвода и теплоотвода вблизи критической точки

Structural phase states in nickel-titanium surface layers doped with silicon by plasma immersion ion implantation

The paper reports on a study of NiTi-based alloys used for manufacturing self-expanding intravascular stents to elucidate how the technological modes of plasma immersion ion implantation with silicon influence the chemical an