Методичні вказівки до виконання курсової роботи з курсу "Організація комп'ютерних мереж"

Students are required to produce a term project building upon and complementing the material covered in class. The topic of the project should be related to making Ethernet cable, Network design, network security. A set of suggested projects is attached below. Each of you is required to pair up with another student to form a team of two members for the project. The final result of the project will be a technical report and a presentation. Students participate in computer networking courses during third course. Computer networking projects give students hands-on experience to learn and digest the course materials being taught. These course project also give students practical experience, especially for those who plan to continue their careers within the field

Методичні вказівки до виконання курсової роботи по курсу "Алгоритми та структури даних"

Guidance for course work on "Algorithms and Data Structures" is a part of methods of the course "Algorithms and Data Structures". Course work is performed in 3 semester. The course work must consolidates theoretical knowledge and practical skills obtained in the study of lecture and practical parts of the course. The guidance covers the key issues related to the course work, the processing of explanatory notes to course work, and the defense of student work

The research of the soil moisture satellite measurements accuracy depending on the underlying surface characteristics

The work is devoted to the assessment of the possibility of using satellite data to determine soil moisture. The direct satellite observations were compared with the direct observations at the stations. Pearson correlation coefficient and the relative errors were calculated. The comparison of the data from the direct measurements of the soil moisture and satellite measurements showed that for the 52% of the stations the correlation coefficients exceeded 0.5

Engineering yeast for high-level production of stilbenoid antioxidants

Stilbenoids, including resveratrol and its methylated derivatives, are natural potent antioxidants, produced by some plants in trace amounts as defense compounds. Extraction of stilbenoids from natural sources is costly due to their low abundance and often limited availability of the plant. Here we engineered the yeast Saccharomyces cerevisiae for production of stilbenoids on a simple mineral medium typically used for industrial production. We applied a pull-push-block strain engineering strategy that included overexpression of the resveratrol biosynthesis pathway, optimization of the electron transfer to the cytochrome P450 monooxygenase, increase of the precursors supply, and decrease of the pathway intermediates degradation. Fed-batch fermentation of the final strain resulted in a final titer of 800 mg l(-1) resveratrol, which is by far the highest titer reported to date for production of resveratrol from glucose. We further integrated heterologous methyltransferases into the resveratrol platform strain and hereby demonstrated for the first time de novo biosynthesis of pinostilbene and pterostilbene, which have better stability and uptake in the human body, from glucose

Evaluation of satellite data on soil moisture in the South-West region of the Baikal

The present paper presents characteristics of correlation between soil moisture observations obtained from a satellite and direct observations during the warm period of 2011 and 2012 in the area of the Tunka Basin. The factors influencing the relationship are considered. It is shown that the updated satellite data on moisture of the upper soil layer and those of direct observations at a depth of 15 cm have a satisfactory relationship

Establishment of a yeast platform strain for production of p-coumaric acid through metabolic engineering of aromatic amino acid biosynthesis

Aromatic amino acids are precursors of numerous plant secondary metabolites with diverse biological functions. Many of these secondary metabolites are already being used as active pharmaceutical or nutraceutical ingredients, and there are numerous exploratory studies of other compounds with promising applications. p-Coumaric acid is derived from aromatic amino acids and, besides being a valuable chemical building block, it serves as precursor for biosynthesis of many secondary metabolites, such as polyphenols, flavonoids, and some polyketides. Here we developed a p-coumaric acid-overproducing Saccharomyces cerevisiae platform strain. First, we reduced by-product formation by knocking out phenylpyruvate decarboxylase ARO10 and pyruvate decarboxylase PDC5. Second, different versions of feedback-resistant DAHP synthase and chorismate mutase were overexpressed. Finally, we identified shikimate kinase as another important flux-controlling step in the aromatic amino acid pathway by overexpressing enzymes from Escherichia coli, homologous to the pentafunctional enzyme Aro1p and to the bifunctional chorismate synthase-flavin reductase Aro2p. The highest titer of p-coumaric acid of 1.93\ub10.26gL-1 was obtained, when overexpressing tyrosine ammonia-lyase TAL from Flavobacterium johnsoniaeu, DAHP synthase ARO4K229L, chorismate mutase ARO7G141S and E. coli shikimate kinase II (aroL) in δpdc5δaro10 strain background. To our knowledge this is the highest reported titer of an aromatic compound produced by yeast. The developed S. cerevisiae strain represents an attractive platform host for production of p-coumaric-acid derived secondary metabolites, such as flavonoids, polyphenols, and polyketides

“Non-Male” Professions in the Late Soviet Period: The Foundations of Gender Imbalance

Статься посвящена анализу гендерного дисбаланса в профессиональных сферах в позднесоветский период. Автор выявил факторы, которые влияли на представления о гендерной окрашенности профессий в СССР, и то, что определенные профессии считались «немужскими».The article is devoted to the analysis of gender imbalance of professions in the late Soviet period. Author found the factors, which affected representations of gender characteristics of professions in USSR, and tried to understand why some professions were considered as «non-male»