Submicron active-passive integration for InP-based membranes on silicon

The high vertical index contrast and the small thickness of thin InP-based membrane structures bonded with BCB on Silicon allow the realization of very small devices. To make photonic integrated circuits with both passive and active components in these membranes, active-passive integration on a small scale is essential. In this paper we will present our results on sub-micrometer active areas for membrane applications

Extremely uniform lasing wavelengths of InP microdisk lasers heterogeneously integrated on SOI

A standard deviation in lasing wavelength lower than 500pm is characterized on nominally identical and optically-pumped microdisk lasers, heterogeneously integrated on the same SOI circuit. This lasing wavelength uniformity is obtained using electron-beam lithography

An observational and theoretical view of the radial distribution of HI gas in galaxies

We analyze the radial distribution of HI gas for 23 disk galaxies with unusually high HI content from the Bluedisk sample, along with a similar-sized sample of "normal" galaxies. We propose an empirical model to fit the radial profile of the HI surface density, an exponential function with a depression near the center. The radial HI surface density profiles are very homogeneous in the outer regions of the galaxy; the exponentially declining part of the profile has a scale-length of $\sim 0.18$ R1, where R1 is the radius where the column density of the HI is 1 M$_{\odot}$ pc$^{-2}$. This holds for all galaxies, independent of their stellar or HI mass. The homogenous outer profiles, combined with the limited range in HI surface density in the non-exponential inner disk, results in the well-known tight relation between HI size and HI mass. By comparing the radial profiles of the HI-rich galaxies with those of the control systems, we deduce that in about half the galaxies, most of the excess gas lies outside the stellar disk, in the exponentially declining outer regions of the HI disk. In the other half, the excess is more centrally peaked. We compare our results with existing smoothed-particle hydrodynamical simulations and semi-analytic models of disk galaxy formation in a $\Lambda$ Cold Dark Matter universe. Both the hydro simulations and the semi-analytic models reproduce the HI surface density profiles and the HI size-mass relation without further tuning of the simulation and model inputs. In the semi-analytic models, the universal shape of the outer HI radial profiles is a consequence of the {\em assumption} that infalling gas is always distributed exponentially. The conversion of atomic gas to molecular form explains the limited range of HI surface densities in the inner disk. These two factors produce the tight HI mass-size relation.Comment: 15 pages, 14 figures, submitted to MNRA

An HI View of Galaxy Conformity: HI-rich Environment around HI-excess Galaxies

Using data taken as part of the Bluedisk project we study the connection between neutral hydrogen (HI) in the environment of spiral galaxies and that in the galaxies themselves. We measure the total HI mass present in the environment in a statistical way by studying the distribution of noise peaks in the HI data cubes obtained for 40 galaxies observed with WSRT. We find that galaxies whose HI mass fraction is high relative to standard scaling relations have an excess HI mass in the surrounding environment as well. Gas in the environment consists of gas clumps which are individually below the detection limit of our HI data. These clumps may be hosted by small satellite galaxies and\or be the high-density peaks of a more diffuse gas distribution in the inter-galactic medium. We interpret this result as an indication for a picture in which the HI-rich central galaxies accrete gas from an extended gas reservoir present in their environment.Comment: 15 pages, 13 figures. Accepted for publication in MNRA

A Survey on Deep Learning in Medical Image Analysis

Deep learning algorithms, in particular convolutional networks, have rapidly become a methodology of choice for analyzing medical images. This paper reviews the major deep learning concepts pertinent to medical image analysis and summarizes over 300 contributions to the field, most of which appeared in the last year. We survey the use of deep learning for image classification, object detection, segmentation, registration, and other tasks and provide concise overviews of studies per application area. Open challenges and directions for future research are discussed.Comment: Revised survey includes expanded discussion section and reworked introductory section on common deep architectures. Added missed papers from before Feb 1st 201

Electrohydrodynamic drying versus conventional drying methods: A comparison of key performance indicators

Preserving fruits and vegetables by drying is a traditional yet effective way of reducing food waste. Existing drying methods are either energy-intensive or lead to a significant reduction in product quality. Electrohydrodynamic (EHD) drying is an energy-efficient low-temperature drying method that presents an opportunity to comply with the current challenges of existing drying methods. However, despite its promising characteristics, EHD drying is yet to be accepted by industry and farmers. The adoption of EHD drying is hindered due to different reasons, such as uncertainties surrounding its scalability, quality of dried product, cost of operation, and sustainability compared to conventional drying methods. To address these concerns, this study quantifies and benchmarks the Key Performance Indicators (KPIs) of EHD drying compared to the standard conventional drying methods based on lab-scale experiments. These drying methods include hot-air, freeze, microwave, and solar drying. The results show that drying food using EHD is at least 1.6, 20, and 70 times more energy-efficient than the microwave, freeze, and hot-air, respectively. Similar results could be observed for exergy efficiency. EHD drying has superior product quality compared to other drying methods. For instance, it could retain 62% higher total phenolic content with 21% less color degradation than freeze-drying. Although microwave drying resulted in significantly higher drying kinetics than other techniques, EHD performed better than solar and freeze-drying but was comparable with hot-air drying. EHD drying also shows promising results in economic performance assessment. It is the cheapest drying method after solar drying and has the highest estimated net present value (NPV) after hot-air drying. Overall, compared to the currently used drying methods for small to medium-scale drying, EHD was found to be a more exergy and energy-efficient, cost-effective, and sustainable alternative that can provide higher-quality dried products. However, its drying kinetics should be improved for industrial applications

The rise of pinnacle reefs : a step change in marine evolution triggered by perturbation of the global carbon cycle

The first appearance of pinnacle reef tracts, composed of hundreds to thousands of localized biogenic structures protruding tens to hundreds of meters above the surrounding mid-Silurian seafloor, represents a step change in the evolution of the marine biosphere. This change in seafloor morphology opened a host of new ecological niches that served as "evolutionary cradles" for organism diversification. However, the exact timing and driver's of this event remain poorly understood. These uncertainties remain, in large part, due to a paucity of index fossils in the reef facies, the difficulty of correlating between the offshore pinnacle reefs and more temporally well-constrained shallow marine fades, and cryptic unconformities that separate amalgamated reefs. Here we use delta C-13(carb) stratigraphy within a sequence stratigraphic framework to unravel these complex relationships and constrain the origination of Silurian pinnacle reef tracts in the North American midcontinent to near the Pt. celloni Superzone-Pt. am. amorphognathoides Zonal Group boundary of the mid-Telychian Stage. In addition, we identify a striking relationship between pulses of reef development and changes in global delta C-13(carb) values and sea level. Viewed through this new perspective, we correlate prolific periods of reef development with short-lived carbon isotope (delta C-13(carb)) excursions and eustatic sea level change that, ultimately, reflect perturbations to the global carbon cycle. From changes in the dominance of microbial reefs of the Cambrian to metazoan colonization of reefs in the Middle Ordovician, through the subsequent collapse of metazoan diversity with the Late Ordovician mass extinction, and the first appearance of early Silurian (Llandovery) pinnacle reef tracts and their proliferation during the late Silurian (Wenlock-Pridoli) and Devonian, major reef formation intervals increasingly coincide with delta C-13(carb) excursions. These patterns suggest that Paleozoic reef evolution was the product of environmental forcing by perturbations of the global carbon cycle

Circle drawing as evaluative movement task in stroke rehabilitation: an explorative study

<p>Abstract</p> <p>Background</p> <p>The majority of stroke survivors have to cope with deficits in arm function, which is often measured with subjective clinical scales. The objective of this study is to examine whether circle drawing metrics are suitable objective outcome measures for measuring upper extremity function of stroke survivors.</p> <p>Methods</p> <p>Stroke survivors (n = 16) and healthy subjects (n = 20) drew circles, as big and as round as possible, above a table top. Joint angles and positions were measured. Circle area and roundness were calculated, and synergistic movement patterns were identified based on simultaneous changes of the elevation angle and elbow angle.</p> <p>Results</p> <p>Stroke survivors had statistically significant lower values for circle area, roundness and joint excursions, compared to healthy subjects. Stroke survivors moved significantly more within synergistic movement patterns, compared to healthy subjects. Strong correlations between the proximal upper extremity part of the Fugl-Meyer scale and circle area, roundness, joint excursions and the use of synergistic movement patterns were found.</p> <p>Conclusions</p> <p>The present study showed statistically significant differences in circle area, roundness and the use of synergistic movement patterns between healthy subjects and stroke survivors. These circle metrics are strongly correlated to stroke severity, as indicated by the proximal upper extremity part of the FM score.</p> <p>In clinical practice, circle area and roundness can give useful objective information regarding arm function of stroke survivors. In a research setting, outcome measures addressing the occurrence of synergistic movement patterns can help to increase understanding of mechanisms involved in restoration of post stroke upper extremity function.</p

Gas-phase metallicity profiles of the Bluedisk galaxies: Is metallicity in a local star formation regulated equilibrium?

As part of the Bluedisk survey, we analyse the radial gas-phase metallicity profiles of 50 late-type galaxies. We compare the metallicity profiles of a sample of H I-rich galaxies against a control sample of H I-`normal' galaxies. We find the metallicity gradient of a galaxy to be strongly correlated with its H I mass fraction (M(H I) / M_{*}). We note that some galaxies exhibit a steeper metallicity profile in the outer disc than in the inner disc. These galaxies are found in both the H I-rich and control samples. This contradicts a previous indication that these outer drops are exclusive to H I-rich galaxies. These effects are not driven by bars, although we do find some indication that barred galaxies have flatter metallicity profiles. By applying a simple analytical model, we are able to account for the variety of metallicity profiles that the two samples present. The success of this model implies that the metallicity in these isolated galaxies may be in a local equilibrium, regulated by star formation. This insight could provide an explanation of the observed local mass-metallicity relation