79 research outputs found
Cellulose acetate membranes functionalized with resveratrol by covalent immobilization for improved osseointegration
Covalent immobilization of resveratrol onto cellulose acetate polymeric membranes used as coating on a Mg-1Ca-0.2Mn-0.6Zr alloy is presented for potential application in the improvement of osseointegration processes. For this purpose, cellulose acetate membrane is hydrolysed in the presence of potassium hydroxide, followed by covalent immobilization of aminopropyl triethoxy silane. Resveratrol was immobilized onto membranes using glutaraldehyde as linker. The newly synthesised functional membranes were thoroughly characterized for their structural characteristics determination employing X-ray photoelectron spectroscopy (XPS), infrared spectroscopy (FT-IR), Raman spectroscopy, thermogravimetric analysis (TGA/DTG) and scanning electron microscopy (SEM) techniques. Subsequently, in vitro cellular tests were performed for evaluating the cytotoxicity biocompatibility of synthesized materials and also the osseointegration potential of obtained derivatised membrane material. It was demonstrated that both polymeric membranes support viability and proliferation of the pre-osteoblastic MC3T3-E1 cells, thus providing a good protection against the potential harmful effects of the compounds released from coated alloys. Furthermore, cellulose acetate membrane functionalized with resveratrol exhibits a significant increase in alkaline phosphatase activity and extracellular matrix mineralization, suggesting its suitability to function as an implant surface coating for guided bone regeneration
Advanced Scanning Electron Microscopy Methods and Applications to Integrated Circuit Failure Analysis
Semiconductor device failure analysis using the scanning electron microscope (SEM) has become a standard component of integrated circuit fabrication. Improvements in SEM capabilities and in digital imaging and processing have advanced standard acquisition modes and have promoted new failure analysis methods. The physical basis of various data acquisition modes, both standard and new, and their implementation on a computer controlled SEM image acquisition/processing system are discussed, emphasizing the advantages of each method. Design considerations for an integrated, online failure analysis system are also described. Recent developments in the integration of the information provided by electron beam analysis, conventional integrated circuit (IC) testing, computer-aided design (CAD), and device parameter testing into a single system promise to provide powerful future tools for failure analysis
Atomic-scale confinement of optical fields
In the presence of matter there is no fundamental limit preventing
confinement of visible light even down to atomic scales. Achieving such
confinement and the corresponding intensity enhancement inevitably requires
simultaneous control over atomic-scale details of material structures and over
the optical modes that such structures support. By means of self-assembly we
have obtained side-by-side aligned gold nanorod dimers with robust
atomically-defined gaps reaching below 0.5 nm. The existence of
atomically-confined light fields in these gaps is demonstrated by observing
extreme Coulomb splitting of corresponding symmetric and anti-symmetric dimer
eigenmodes of more than 800 meV in white-light scattering experiments. Our
results open new perspectives for atomically-resolved spectroscopic imaging,
deeply nonlinear optics, ultra-sensing, cavity optomechanics as well as for the
realization of novel quantum-optical devices
Ultrafast nano-focusing with full optical waveform control
The spatial confinement and temporal control of an optical excitation on
nanometer length scales and femtosecond time scales has been a long-standing
challenge in optics. It would provide spectroscopic access to the elementary
optical excitations in matter on their natural length and time scales and
enable applications from ultrafast nano-opto-electronics to single molecule
quantum coherent control. Previous approaches have largely focused on using
surface plasmon polariton (SPP) resonant nanostructures or SPP waveguides to
generate nanometer localized excitations. However, these implementations
generally suffer from mode mismatch between the far-field propagating light and
the near-field confinement. In addition, the spatial localization in itself may
depend on the spectral phase and amplitude of the driving laser pulse thus
limiting the degrees of freedom available to independently control the
nano-optical waveform. Here we utilize femtosecond broadband SPP coupling, by
laterally chirped fan gratings, onto the shaft of a monolithic noble metal tip,
leading to adiabatic SPP compression and localization at the tip apex. In
combination with spectral pulse shaping with feedback on the intrinsic
nonlinear response of the tip apex, we demonstrate the continuous micro- to
nano-scale self-similar mode matched transformation of the propagating
femtosecond SPP field into a 20 nm spatially and 16 fs temporally confined
light pulse at the tip apex. Furthermore, with the essentially wavelength and
phase independent 3D focusing mechanism we show the generation of arbitrary
optical waveforms nanofocused at the tip. This unique femtosecond nano-torch
with high nano-scale power delivery in free space and full spectral and
temporal control opens the door for the extension of the powerful nonlinear and
ultrafast vibrational and electronic spectroscopies to the nanoscale.Comment: Contains manuscript with 4 figures as well as supplementary material
with 2 figure
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Threads and Boundaries: Rethinking the Intellectual History of International Relations
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A polarizing situation: Taking an in-plane perspective for next-generation near-field studies
CercetÄri privind evolutia principalilor dÄunÄtori ai platanului Ăźn RomĂąnia
n recent years, in Bucharest and in other urban centres in our
country began to be placed Platanus spp. trees. In the area of Bucharest, in the
year 2014 and 2015 was an extension of two dangerous Platanusâ pests
[Thesycamore lace bug (Corythucha ciliata Say, 1832 - Hemiptera: Tingidae)
and leaf-mining moth (Phyllonorycter platani Staudinger, 1870 - Lepidoptera:
Gracilariidae)]. Research has followed the evolution of these pests in the
nursery from Bolintin Deal and identify other potential pests that have the
potential to attack the Platanus spp.. In order to carry out effective and well
timed control methods, bio monitoring studies of the pests are necessary. The
biology, ecology and the vulnerable life periods of the pests were studied. It was
noted intensity and frequency of infested leaves, calculating the degree of
attack, these indicators are variable, depending on the pest life cycle or the
period studied. For Corythucha ciliata recorded population was between the 2
and 8 exemplars/leaf attacked, while for Phyllonorycter platani attack was
between 441 and 549 leaves attacked, regarding the number of mine / leaf
between 1 and 10 and ranges of attacked leaf surface is between 1.4 and
5.5/attacked leave. Are presented other pests identified in the nursery
Enthalpies of Combustion and Formation of Histidine Stereoisomers
The combustion energy of histidine enantiomers (L and D) and of their racemic mixture was measured experimentally. The following values for the enthalpies of formation corresponding to the crystalline state were derived (L = â451.7, D = â448.7, DL = â451.5âkJ·molâ1), and information concerning their stability was obtained by correlating the values of the above thermochemical quantity with the structure of the molecules by using the group additivity scheme. The samples were characterized using a simultaneous thermogravimetry (TG) coupled with differential scanning calorimetry (DSC) techniques in the temperature range between ambient and beyond melting-decomposition, and the corresponding parameters were calculated. The high values of the decomposition temperatures highlight the stability of the compounds. The decomposition reactions are discussed in terms of DSC and TG data, obtained by us and other researchers
Assessing the Indoor Pollutants Effect on Ornamental Plants Leaves by FT-IR Spectroscopy
Air pollution has become a mass phenomenon, a major and global problem of modern society, affecting billions of people and environment. People are exposed to various levels of pollutants not just in the outdoor environment, but also in indoors. The quality of life and well-being of employees can be increased by incorporating ornamental plants in the work environment. Among the great variety of plants species able to remove/reduce indoor air pollutants Dracaena deremensis, Sansevieria trifasciata and Ficus elastica were hereby investigated. Their ability to remove chemical pollutants was evaluated in real-life conditions and the changes induced by the environmental stress on the structure and biochemical composition of the plants leaves were evidenced by the Fourier transform infrared spectroscopy. The most pronounced concentration decrease was noticed for the COâ (58.33% removed concentration), whereas the mean value of the removed concentration of other chemical pollutants was of â 25%. The Fourier transform infrared spectra analysis revealed that, although the plants are subjected to the chemical pollutants action, they maintain the structure by adjusting their metabolism. A decrease in the overall protein contribution in the amide bands and an increase of the bands assigned to polysaccharide vibrations, illustrate the consequences of the pollution action. Moreover, the chlorophyll presence is evidenced in the IR spectra of all samples by the bands around 1040, 1445, 1620, and 1735 cm^{-1}. The results show that the Fourier transform infrared spectra are an important source of information for the rapid characterization of the chemical structure of the biological systems under environmental stress
P.862 Oppositional defiant disorder - conduct disorder â antisocial personality disorder continuum investigated over a 14-year timespan
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