Effects of misalignment on the nonlinear dynamics of a two-shaft rotor-bearing-gear coupling system with rub-impact fault

In rotor-bearing system, the misalignment can lead to secondary faults, such as the rub-impact fault. How the development of misalignment could affect the rub-impact force and other dynamic responses is important for the vibration control and fault diagnosis of rotor system. In this paper, a mathematical model of a two-shaft rotor-bearing- gear coupling system is established. The model is validated through the misaligned force of gear coupling, the supporting force of the lubricated ball bearing and the whole rotor response. To overcome the limit of traditional approaches and further dig out fault characteristics, the time-frequency method is introduced to analyze the dynamic response from both the time and frequency domains points of view. It is found the misalignment effect on rotor dynamic responses is mainly focused in high rotating speed range. The development of misalignment has an obvious adverse effect on the rotor stability. Some intermittent components in low frequency range due to the occurrence and development of misalignment can be found affecting the rotor stability at low speed range, and the high frequency rub-impact components can be found responsible for the unstable state of rotor

Association of lymphocyte subsets with the efficacy and prognosis of PD‑1 inhibitor therapy in advanced gastric cancer: results from a monocentric retrospective study

Abstract Purpose This retrospective study aimed to investigate the changes in peripheral blood lymphocyte subsets before and after immunotherapy in patients with advanced gastric cancer and their relationship n with the therapeutic efficacy and clinical prognosis. Methods Peripheral blood lymphocyte subsets, including CD4 + T cells, CD8 + T cells, CD4+/CD8 + ratio, NK cells, Treg cells, and B cells, were collected from 195 patients with advanced gastric cancer who were admitted to the First Hospital of Shanxi Medical University with immunotherapy from January 2020 to October 2021, at the time of diagnosis of advanced gastric cancer, before immunotherapy and after 3 cycles of immunotherapy. T-tests were used to examine the factors influencing the patients’ peripheral blood lymphocyte subsets and the changes after immunotherapy. To examine the relationship between lymphocyte subsets and treatment outcomes, ROC curves were plotted using a logistic regression. Kaplan–Meier curve was drawn, and the Log Rank test was carried out to compare the differences in PFS between the different groups. Cox proportional hazards regression model was used to analyze the factors affecting PFS after calibration of other variables. Results The proportion of peripheral blood lymphocyte subsets in patients with advanced gastric cancer was affected by age and PD-L1 level. Compared to the baseline, the treatment effective group had higher proportions of CD4 + T cells, a higher CD4+/CD8 + ratio, NK cells and Treg cells, and lower proportions of CD8 + T cells and B cells in the peripheral blood after three cycles of immunotherapy. In the treatment-naive group, there were no significant differences in the lymphocyte subsets. With cut-off values of 30.60% and 18.00%, baseline CD4 + T cell and NK cell ratios were independent predictors of immunotherapy efficacy and PFS. Treg cell ratio, gender, PD-L1 levels, and MMR status all predicted PFS independently. Conclusion The proportion of peripheral blood lymphocyte subsets was modified in patients who responded to PD-1 inhibitors. Different lymphocyte subpopulation levels can be used as biomarkers to predict immunotherapy efficacy and clinical prognosis in patients with advanced gastric cancer

Simulation and Experiment study of ball defects of a two rotors-ball bearing-gear coupling system

A model of a two rotors-ball bearing-gear coupling systems which considering ball defects on bearing was established. In this model the meshing force of gear coupling and ball defects on bearing was considered. A test facility was constructed to verify the simulation results. After simulation and experiment, it was found that there are sideband frequencies beside VC frequency and its multiple frequencies can be found in the faulted rotor system in the spectrum. From the acceleration signal of experiment, it was found the signal of the bearing fault performs as impacts in the high frequency range without any patterns. The characteristics of ball defects of bearing on a two rotors-ball bearing-gear coupling systems were analyzed. It can help analyze the stability of the system and the fault characteristic of ball bearing

Study on the Elastic–Plastic Correlation of Low-Cycle Fatigue for Variable Asymmetric Loadings

The mean stress effect in fatigue life varies by material and loading conditions. Therefore, a classical low cycle fatigue (LCF) model based on mean stress correction shows limits in asymmetric loading cases in both accuracy and applicability. In this paper, the effect of strain ratio (R) on LCF life is analyzed and a strain ratio-based model is presented for asymmetric loading cases. Two correction factors are introduced to express correlations between strain ratio and fatigue strength coefficient and between strain ratio and fatigue ductility coefficient. Verifications are conducted through four materials under different strain ratios: high-pressure tubing steel (HPTS), 2124-T851 aluminum alloy, epoxy resin and AZ61A magnesium alloy. Compared with current widely used LCF models, the proposed model shows a better life prediction accuracy and higher potential in implementation in symmetric and asymmetric loading cases for different materials. It is also found that the strain ratio-based correction is able to consider the damage of ratcheting strain that the mean stress-based models cannot

Simulation and Experiment study of ball defects of a two rotors-ball bearing-gear coupling system

A model of a two rotors-ball bearing-gear coupling systems which considering ball defects on bearing was established. In this model the meshing force of gear coupling and ball defects on bearing was considered. A test facility was constructed to verify the simulation results. After simulation and experiment, it was found that there are sideband frequencies beside VC frequency and its multiple frequencies can be found in the faulted rotor system in the spectrum. From the acceleration signal of experiment, it was found the signal of the bearing fault performs as impacts in the high frequency range without any patterns. The characteristics of ball defects of bearing on a two rotors-ball bearing-gear coupling systems were analyzed. It can help analyze the stability of the system and the fault characteristic of ball bearing

Performance Analysis of a Fiber Reinforced Plastic Oil Cooler Cover Considering the Anisotropic Behavior of the Fiber Reinforced PA66

In this paper, a simulation method based on an orthogonal anisotropic material is proposed. A numerical example using a simple plate is presented to show the difference in the static performance between the orthogonal anisotropic and the isotropic models. Comparing with the tested modal data of a diesel engine oil cooler cover made by glass fiber reinforced polyamide 66 (PA66), the proposed simulation method was confirmed to be much closer to reality than the general isotropic model. After that, a comprehensive performance comparison between the plastic oil cooler covers with the orthogonal anisotropic and the isotropic fiber orientations was carried out including a static deformation and stress analysis under a pressure-temperature coupled load, a forced response analysis, and an acoustic analysis under real operating conditions. The results show that the stress, the deformation, the peak vibration velocity, and the overall sound power level of the orthogonal anisotropic model are different from that obtained with the isotropic model. More importantly, the proposed method can provide a much more detailed frequency content compared to the isotropic model

Additional file 1 of Association of lymphocyte subsets with the efficacy and prognosis of PD‑1 inhibitor therapy in advanced gastric cancer: results from a monocentric retrospective study

Supplementary Material

Flocking Bird Strikes on Engine Fan Blades and Their Effect on Rotor System: A Numerical Simulation

Bird strikes are a common, serious, and devastating event in aviation accidents, and multi-bird strikes are also frequently reported. A numerical multi-bird-strike simulation was performed to investigate the effect of flocking birds striking on engine blades. The smooth particle hydrodynamics (SPH) method was adopted in the hemispherical-ended bird substitute model, and the finite element method (FEM) with EOS state equation was adopted for the fan model as well. Impact analyses have been presented using different flocking birds and impact location distributions. A “0-2-1” supported rotor system dynamic model was established to study the effect of the multi-bird-strike impact forces on the rotor system. The results show that bird-strike severity is related to the impact location distribution, with blade-root impacts being the most dangerous. The small flocking bird strikes had little effect on the fan compared to the cases of medium flocking birds and the large single bird. The dynamic response of the fan to the small flocking birds was the same as without a bird strike, while the other cases changed the motion period and excited the rotor first-order vibration

Flocking Bird Strikes on Engine Fan Blades and Their Effect on Rotor System: A Numerical Simulation

Bird strikes are a common, serious, and devastating event in aviation accidents, and multi-bird strikes are also frequently reported. A numerical multi-bird-strike simulation was performed to investigate the effect of flocking birds striking on engine blades. The smooth particle hydrodynamics (SPH) method was adopted in the hemispherical-ended bird substitute model, and the finite element method (FEM) with EOS state equation was adopted for the fan model as well. Impact analyses have been presented using different flocking birds and impact location distributions. A “0-2-1” supported rotor system dynamic model was established to study the effect of the multi-bird-strike impact forces on the rotor system. The results show that bird-strike severity is related to the impact location distribution, with blade-root impacts being the most dangerous. The small flocking bird strikes had little effect on the fan compared to the cases of medium flocking birds and the large single bird. The dynamic response of the fan to the small flocking birds was the same as without a bird strike, while the other cases changed the motion period and excited the rotor first-order vibration

撞击位置与风扇转速对鸟撞过程的影响

Bird impact on fan blades poses a serious threat to the operational safety of aircraft engines.In this study, a real bird model of mallard duck was developed using the smooth particle hydrodynamics method based on a CT scan of a mallard duck.The accuracy of the real bird model was verified by comparing the simulation results of the impact on a plate of real bird model and simplified traditional bird model with the results of Wilbeck's tests.The transient impact responses of bird body and fan blade as the bird was striking a static and a rotating fan blade were comparatively analyzed.To study the effect of fan rotational speed on the bird-impact process, 836r/min, 1984r/min, 3344r/min, and 3772r/min were selected as fan rotational speed.To study the effects of impact location on the bird-impact process, 1/6, 2/6, 3/6, 4/6 and 5/6 of the blade height were selected as impact locations.The results show that blade rotation has a direct impact on the number of bird block cuts, the mass of a single bird block, and the number of impacted blades.Without considering the blade rotation conditions, the contact force, blade root stress, and blade leading edge stress are significantly lower than that when the blade rotation conditions are considered, which makes the prediction of blade stress and damage conservative and inadequate for use in the design of blade strength.Therefore, the blade rotation motion should be considered in the study of bird impact.The interaction mode between the bird and blade at 836r/min speed obviously differs from that at other rotational speeds.The kinetic energy of the bird decreases at a rotational speed of 836r/min, and increases at other rotational speeds, and the increment of the kinetic energy of the bird increases with increases in rotational speed.The leading-edge peak stress at 836r/min is greater than that at 1984r/min;at other rotational speeds, the peak stress of the leading edge increases with increases in the rotational speed.The contact force and blade root stress increase with increases in the rotational speed.With increases in the impact height, the contact force, kinetic-energy increment of the bird body, peak stress of the blade root, kinetic energy of the bird body, and the stress on the leading edge of blade all increase first and then decrease under the combined action of the relative velocity of the impact point and twist angle of the blade.The peak stress of the leading edge and the increment of the kinetic energy of the bird are greatest when impact occurs at 3/6 blade height, and the peak stress of the blade root and the contact force are greatest when impact occurs at 4/6 blade height.Novel Aerospace MaterialsSanitary Engineerin