564 research outputs found
Use of biomarkers or echocardiography in pulmonary embolism: the Swiss Venous Thromboembolism Registry
Background: Cardiac biomarkers and echocardiography for assessing right ventricular function are recommended to risk stratify patients with acute non-massive pulmonary embolism (PE), but it remains unclear if these tests are performed systematically in daily practice. Design and methods: Overall, 587 patients with acute non-massive PE from 18 hospitals were enrolled in the Swiss Venous Thromboembolism Registry (SWIVTER): 178 (30%) neither had a biomarker test nor an echocardiographic evaluation, 196 (34%) had a biomarker test only, 47 (8%) had an echocardiogram only and 166 (28%) had both tests. Results: Among the 409 (70%) patients with biomarkers or echocardiography, 210 (51%) had at least one positive test and 67 (16%) had positive biomarkers and right ventricular dysfunction. The ICU admission rates were 5.1% without vs. 5.6% with testing (P = 0.78), and thrombolysis or embolectomy were performed in 2.8% vs. 4.9%, respectively (P = 0.25). In multivariate analysis, syncope [odds ratio (OR): 3.49, 95% confidence interval (CI): 1.20-10.15; P = 0.022], tachycardia (OR: 2.31, 95% CI: 1.37-3.91; P = 0.002) and increasing age (OR: 1.02; 95% CI: 1.01-1.04; P < 0.001) were associated with testing of cardiac risk; outpatient status at the time of PE diagnosis (OR: 2.24, 95% CI: 1.49-3.36; P < 0.001), cancer (OR: 1.81, 95% CI: 1.17-2.79; P = 0.008) and provoked PE (OR: 1.58, 95% CI: 1.05-2.40; P = 0.029) were associated with its absence. Conclusions: Although elderly patients and those with clinically severe PE were more likely to receive a biomarker test or an echocardiogram, these tools were used in only two-thirds of the patients with acute non-massive PE and rarely in combinatio
The Education Track PhD Program in Anatomy at Indiana University School of Medicine: A Decade Producing Anatomy Educator-Scholars
In 2008, the Indiana University School of Medicine (IUSM) admitted its first student to a newly approved PhD program focusing on anatomical education rather than biomedical research. The goal of the Education Track PhD program is twofold: (1) to provide students with extensive training in all of the anatomical sub-disciplines coupled with sufficient teaching experience to be fully prepared to assume major educational responsibilities upon graduation and (2) to train students to conduct rigorous, medical education research and other educational scholarship necessary for promotion and tenure. The 90-credit hour curriculum
includes coursework in anatomy and other biomedical subjects, education, statistics, and electives. For their dissertation work, the students complete a research project about some aspect of medical education. As of December 2017, the Education Track program had admitted 23 students and produced 10 graduates. Two more students are anticipated to graduate by June 2018. All of the graduates were offered faculty appointments (8 tenure track and 2 nontenure track) immediately upon graduation at major universities and medical schools. Four of the graduates were offered positions at IUSM. Eight graduates have appointments in medical school anatomy departments, 1 in a physical therapy department, and 1 in a physician assistant department. None of the graduates have been in their faculty positions long enough yet to have achieved tenure. During the period from 2009 through 2017, the students and graduates of the program gave 84 conference presentations and authored 47 peer-reviewed publications about anatomy or other aspects of medical education. Thus, in the 10 years since its inception, the Education Track program has successfully produced a small but stable supply of doctoral-level anatomy educator-scholars
for a growing academic market.American Association for Anatomy Spring Meetin
Linear magnetoresistance in commercial n-type silicon due to inhomogeneous doping
Free electron theory tells us that resistivity is independent of magnetic
field. In fact, most observations match the semiclassical prediction of a
magnetoresistance that is quadratic at low fields before saturating. However, a
non-saturating linear magnetoresistance has been observed in exotic
semiconductors such as silver chalcogenides, lightly-doped InSb, N-doped InAs,
MnAs-GaAs composites, PrFeAsO, and epitaxial graphene. Here we report the
observation of a large linear magnetoresistance in the ohmic regime in
commonplace commercial n-type silicon wafer. It is well-described by a
classical model of spatially fluctuating donor densities, and may be amplified
by altering the aspect ratio of the sample to enhance current-jetting:
increasing the width tenfold increased the magnetoresistance at 8 T from 445 %
to 4707 % at 35 K. This physical picture may well offer insights into the large
magnetoresistances recently observed in n-type and p-type Si in the non-ohmic
regime.Comment: submitted to Nature Material
Disorder effects in electronic structure of substituted transition metal compounds
Investigating LaNi(1-x)M(x)O3 (M = Mn and Fe), we identify a characteristic
evolution of the spectral function with increasing disorder in presence of
strong interaction effects across the metal-insulator transition. We discuss
these results vis-a-vis existing theories of electronic structure in
simultaneous presence of disorder and interaction.Comment: Revtex, 4 pages, 3 postscript figures (To appear in Phys. Rev. Lett
Measurement of gamma p --> K+ Lambda and gamma p --> K+ Sigma0 at photon energies up to 2.6 GeV
The reactions gamma p --> K+ Lambda and gamma p --> K+ Sigma0 were measured
in the energy range from threshold up to a photon energy of 2.6 GeV. The data
were taken with the SAPHIR detector at the electron stretcher facility, ELSA.
Results on cross sections and hyperon polarizations are presented as a function
of kaon production angle and photon energy. The total cross section for Lambda
production rises steeply with energy close to threshold, whereas the Sigma0
cross section rises slowly to a maximum at about E_gamma = 1.45 GeV. Cross
sections together with their angular decompositions into Legendre polynomials
suggest contributions from resonance production for both reactions. In general,
the induced polarization of Lambda has negative values in the kaon forward
direction and positive values in the backward direction. The magnitude varies
with energy. The polarization of Sigma0 follows a similar angular and energy
dependence as that of Lambda, but with opposite sign.Comment: 21 pages, 25 figures, submitted to Eur. Phys. J.
Metal-insulator Crossover Behavior at the Surface of NiS_2
We have performed a detailed high-resolution electron spectroscopic
investigation of NiS and related Se-substituted compounds
NiSSe, which are known to be gapped insulators in the bulk at all
temperatures. A large spectral weight at the Fermi energy of the room
temperature spectrum, in conjunction with the extreme surface sensitivity of
the experimental probe, however, suggests that the surface layer is metallic at
300 K. Interestingly, the evolution of the spectral function with decreasing
temperature is characterized by a continuous depletion of the single-particle
spectral weight at the Fermi energy and the development of a gap-like structure
below a characteristic temperature, providing evidence for a metal-insulator
crossover behavior at the surfaces of NiS and of related compounds. These
results provide a consistent description of the unusual transport properties
observed in these systems.Comment: 12 pages, 3 figure
Scaling of the Conductivity with Temperature and Uniaxial Stress in Si:B at the Metal-Insulator Transition
Using uniaxial stress to tune Si:B through the metal-insulator transition we
find the conductivity at low temperatures shows an excellent fit to scaling
with temperature and stress on both sides of the transition. The scaling
functions yield the conductivity in the metallic and insulating phases, and
allow a reliable determination of the temperature dependence in the critical
regions on both sides of the transition
K^0 pi^0 Sigma^+ and K^*0 Sigma^+ photoproduction off the proton
The exclusive reactions and , leading to the p 4 final state, have
been measured with a tagged photon beam for incident energies from threshold up
to 2.5 GeV. The experiment has been performed at the tagged photon facility of
the ELSA accelerator (Bonn). The Crystal Barrel and TAPS detectors were
combined to a photon detector system of almost 4 geometrical acceptance.
Differential and total cross sections are reported. At energies close to the
threshold, a flat angular distribution has been observed for the reaction
suggesting dominant s-channel production.
and higher lying hyperon states have been observed. An
enhancement in the forward direction in the angular distributions of the
reaction indicates a -channel exchange
contribution to the reaction mechanism. The experimental data are in reasonable
agreement with recent theoretical predictions.Comment: 11 pages, 13 figures, submitted to EPJ
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