966 research outputs found
Belief Revision in Structured Probabilistic Argumentation
In real-world applications, knowledge bases consisting of all the information
at hand for a specific domain, along with the current state of affairs, are
bound to contain contradictory data coming from different sources, as well as
data with varying degrees of uncertainty attached. Likewise, an important
aspect of the effort associated with maintaining knowledge bases is deciding
what information is no longer useful; pieces of information (such as
intelligence reports) may be outdated, may come from sources that have recently
been discovered to be of low quality, or abundant evidence may be available
that contradicts them. In this paper, we propose a probabilistic structured
argumentation framework that arises from the extension of Presumptive
Defeasible Logic Programming (PreDeLP) with probabilistic models, and argue
that this formalism is capable of addressing the basic issues of handling
contradictory and uncertain data. Then, to address the last issue, we focus on
the study of non-prioritized belief revision operations over probabilistic
PreDeLP programs. We propose a set of rationality postulates -- based on
well-known ones developed for classical knowledge bases -- that characterize
how such operations should behave, and study a class of operators along with
theoretical relationships with the proposed postulates, including a
representation theorem stating the equivalence between this class and the class
of operators characterized by the postulates
A Novel Application of Non-Destructive Readout Technology to Localisation Microscopy.
The fitting precision in localisation microscopy is highly dependent on the signal to noise ratio. To increase the quality of the image it is therefore important to increase the signal to noise ratio of the measurements. We present an imaging system for localisation microscopy based on non-destructive readout camera technology that can increase the signal to noise ratio of localisation based microscopy. This approach allows for much higher frame rates through subsampling a traditional camera frame. By matching the effective exposure to both the start time and duration of a single molecule we diminish the effects of read noise and temporal noise. We demonstrate the application of this novel method to localisation microscopy and show both an increase in the attainable signal to noise ratio of data collection and an increase in the number of detected events
Outskirts of Nearby Disk Galaxies: Star Formation and Stellar Populations
The properties and star formation processes in the far-outer disks of nearby
spiral and dwarf irregular galaxies are reviewed. The origin and structure of
the generally exponential profiles in stellar disks is considered to result
from cosmological infall combined with a non-linear star formation law and a
history of stellar migration and scattering from spirals, bars, and random
collisions with interstellar clouds. In both spirals and dwarfs, the far-outer
disks tend to be older, redder and thicker than the inner disks, with the
overall radial profiles suggesting inside-out star formation plus stellar
scattering in spirals, and outside-in star formation with a possible
contribution from scattering in dwarfs. Dwarf irregulars and the far-outer
parts of spirals both tend to be gas dominated, and the gas radial profile is
often non-exponential although still decreasing with radius. The ratio of
H-alpha to far-UV flux tends to decrease with lower surface brightness in these
regions, suggesting either a change in the initial stellar mass function or the
sampling of that function, or a possible loss of H-alpha photons.Comment: 20 pages, 8 figures, Invited review, Book chapter in "Outskirts of
Galaxies", Eds. J. H. Knapen, J. C. Lee and A. Gil de Paz, Astrophysics and
Space Science Library, Springer, in pres
Mapping the ultrafast flow of harvested solar energy in living photosynthetic cells
Photosynthesis transfers energy efficiently through a series of antenna complexes to the
reaction center where charge separation occurs. Energy transfer in vivo is primarily monitored
by measuring fluorescence signals from the small fraction of excitations that fail to
result in charge separation. Here, we use two-dimensional electronic spectroscopy to follow
the entire energy transfer process in a thriving culture of the purple bacteria, Rhodobacter
sphaeroides. By removing contributions from scattered light, we extract the dynamics of
energy transfer through the dense network of antenna complexes and into the reaction
center. Simulations demonstrate that these dynamics constrain the membrane organization
into small pools of core antenna complexes that rapidly trap energy absorbed by surrounding
peripheral antenna complexes. The rapid trapping and limited back transfer of these excitations
lead to transfer efficiencies of 83% and a small functional light-harvesting unit
The VLT-FLAMES survey of massive stars: observations in the Galactic clusters NGC3293, NGC4755 and NGC6611
We introduce a new survey of massive stars in the Galaxy and the Magellanic
Clouds using the Fibre Large Array Multi-Element Spectrograph (FLAMES)
instrument at the Very Large Telescope (VLT). Here we present observations of
269 Galactic stars with the FLAMES-Giraffe Spectrograph (R ~ 25,000), in fields
centered on the open clusters NGC 3293, NGC 4755 and NGC 6611. These data are
supplemented by a further 50 targets observed with the Fibre-Fed Extended Range
Optical Spectrograph (FEROS, R = 48,000). Following a description of our
scientific motivations and target selection criteria, the data reduction
methods are described; of critical importance the FLAMES reduction pipeline is
found to yield spectra that are in excellent agreement with less automated
methods. Spectral classifications and radial velocity measurements are
presented for each star, with particular attention paid to morphological
peculiarities and evidence of binarity. These observations represent a
significant increase in the known spectral content of NGC 3293 and NGC 4755,
and will serve as standards against which our subsequent FLAMES observations in
the Magellanic Clouds will be compared.Comment: 26 pages, 9 figures (reduced size). Accepted for publication in A&A.
A copy with full res. figures is available from
http://www.ing.iac.es/~cje/flames_mw.ps.gz. Minor changes following
correction of proof
Can cartilage loss be detected in knee osteoarthritis (OA) patients with 3â6 months' observation using advanced image analysis of 3T MRI?
SummaryPurposePrior investigations of magnetic resonance imaging (MRI) biomarkers of cartilage loss in knee osteoarthritis (OA) suggest that trials of interventions which affect this biomarker with adequate statistical power would require large clinical studies of 1â2 years duration. We hypothesized that smaller, shorter duration, âProof of Conceptâ (PoC) studies might be achievable by: (1) selecting a population at high risk of rapid medial tibio-femoral (TF) progression, in conjunction with; (2) high-field MRI (3T), and; (3) using advanced image analysis. The primary outcome was the cartilage thickness in the central medial femur.MethodsMulti-centre, non-randomized, observational cohort study at four sites in the US. Eligible participants were females with knee pain, a body mass index (BMI)â„25kg/m2, symptomatic radiographic evidence of medial TF OA, and varus mal-alignment. The 29 participants had a mean age of 62 years, mean BMI of 36kg/m2, with eight index knees graded as KellgrenâLawrence (K&L)=2 and 21 as K&L=3. Eligible participants had four MRI scans of one knee: two MRIs (1 week apart) were acquired as a baseline with follow-up MRI at 3 and 6 months. A trained operator, blind to time-point but not subject, manually segmented the cartilage from the Dual Echo Steady State water excitation MR images. Anatomically corresponding regions of interest were identified on each image by using a three-dimensional statistical shape model of the endosteal bone surface, and the cartilage thickness (with areas denuded of cartilage included as having zero thickness â ThCtAB) within each region was calculated. The percentage change from baseline at 3 and 6 months was assessed using a log-scale analysis of variance (ANOVA) model including baseline as a covariate. The primary outcome was the change in cartilage thickness within the aspect of central medial femoral condyle exposed within the meniscal window (w) during articulation, neglecting cartilage edges [nuclear (n)] (nwcMF·ThCtAB), with changes in other regions considered as secondary endpoints.ResultsAnatomical mal-alignment ranged from â1.9° to 6.3°, with mean 0.9°. With one exception, no changes in ThCtAB were detected at the 5% level for any of the regions of interest on the TF joint at 3 or 6 months of follow-up. The change in the primary variable (nwcMF·ThCtAB) from (mean) baseline at 3 months from the log-scale ANOVA model was â2.1% [95% confidence interval (CI) (â4.4%, +0.2%)]. The change over 6 months was 0.0% [95% CI (â2.7%, +2.8%)]. The 95% CI for the change from baseline did not include zero for the cartilage thickness within the meniscal window of the lateral tibia (wLT·ThCtAB) at 6 month follow-up (â1.5%, 95% CI [â2.9, â0.2]), but was not significant at the 5% level after correction for multiple comparisons.ConclusionsThe small inconsistent compartment changes, and the relatively high variabilities in cartilage thickness changes seen over time in this study, provide no additional confidence for a 3- or 6-month PoC study using a patient population selected on the basis of risk for rapid progression with the MRI acquisition and analyses employed
Time-reversal violating rotation of polarization plane of light in gas placed in electric field
Rotation of polarization plane of light in gas placed in electric field is
considered. Different factors causing this phenomenon are investigated. Angle
of polarization plane rotation for transition 6S_{1/2} - 7S_{1/2} in cesium
(lambda=539 nm) is estimated. The possibility to observe this effect
experimentally is discussed.Comment: 10 pages, Late
Magnetic Nanoparticles for Power Absorption: optimizing size, shape and magnetic properties
We present a study on the magnetic properties of naked and silica-coated
Fe3O4 nanoparticles with sizes between 5 and 110 nm. Their efficiency as
heating agents was assessed through specific power absorption (SPA)
measurements as a function of particle size and shape. The results show a
strong dependence of the SPA with the particle size, with a maximum around 30
nm, as expected for a Neel relaxation mechanism in single-domain particles. The
SiO2 shell thickness was found to play an important role in the SPA mechanism
by hindering the heat outflow, thus decreasing the heating efficiency. It is
concluded that a compromise between good heating efficiency and surface
functionality for biomedical purposes can be attained by making the SiO2
functional coating as thin as possible.Comment: 15 pages, 7 figures, 2 table
Dynamic Evolution Model of Isothermal Voids and Shocks
We explore self-similar hydrodynamic evolution of central voids embedded in
an isothermal gas of spherical symmetry under the self-gravity. More
specifically, we study voids expanding at constant radial speeds in an
isothermal gas and construct all types of possible void solutions without or
with shocks in surrounding envelopes. We examine properties of void boundaries
and outer envelopes. Voids without shocks are all bounded by overdense shells
and either inflows or outflows in the outer envelope may occur. These
solutions, referred to as type void solutions, are further
divided into subtypes and
according to their characteristic behaviours across the sonic critical line
(SCL). Void solutions with shocks in envelopes are referred to as type
voids and can have both dense and quasi-smooth edges.
Asymptotically, outflows, breezes, inflows, accretions and static outer
envelopes may all surround such type voids. Both cases of
constant and varying temperatures across isothermal shock fronts are analyzed;
they are referred to as types and
void shock solutions. We apply the `phase net matching procedure' to construct
various self-similar void solutions. We also present analysis on void
generation mechanisms and describe several astrophysical applications. By
including self-gravity, gas pressure and shocks, our isothermal self-similar
void (ISSV) model is adaptable to various astrophysical systems such as
planetary nebulae, hot bubbles and superbubbles in the interstellar medium as
well as supernova remnants.Comment: 24 pages, 13 figuers, accepted by ApS
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