100 research outputs found
Impurity induced resonant state in a pseudogap state of a high temperature superconductor
We predict a resonance impurity state generated by the substitution of one Cu
atom with a nonmagnetic atom, such as Zn, in the pseudogap state of a high-T_c
superconductor. The precise microscopic origin of the pseudogap is not
important for this state to be formed, in particular this resonance will be
present even in the absence of superconducting fluctuations in the normal
state. In the presence of superconducting fluctuations, we predict the
existence of a counterpart impurity peak on a symmetric bias.
The nature of impurity resonance is similar to the previously studied
resonance in the d-wave superconducting state.Comment: 4 pages, 2 figure
A comparison of clinical pharmacodynamics of different administration schedules of oral topotecan (Hycamtin)
Prolonged exposure to topotecan in in vitro and in vivo experiments has
yielded the highest antitumor efficacy. An oral formulation of topotecan
with a bioavailability of 32-44% in humans enables convenient prolonged
administration. Pharmacokinetic/pharmacodynamic relationships from four
Phase I studies with different schedules of administration of oral
topotecan in 99 adult patients with malignant solid tumors refractory to
standard forms of chemotherapy were compared. Topotecan was administered
as follows: (a) once daily (o.d.) for 5 days every 21 days (29 patients);
(b) o.d. for 10 days every 21 days (19 patients); (c) twice daily (b.i.d.)
for 10 days every 21 days (20 patients); and (d) b.i.d. for 21 days every
28 days (31 patients). Pharmacokinetic analysis was performed in 55
patients using a validated high-performance liquid chromatographic assay
and noncompartmental pharmacokinetic me
Probing exotic phenomena at the interface of nuclear and particle physics with the electric dipole moments of diamagnetic atoms: A unique window to hadronic and semi-leptonic CP violation
The current status of electric dipole moments of diamagnetic atoms which
involves the synergy between atomic experiments and three different theoretical
areas -- particle, nuclear and atomic is reviewed. Various models of particle
physics that predict CP violation, which is necessary for the existence of such
electric dipole moments, are presented. These include the standard model of
particle physics and various extensions of it. Effective hadron level combined
charge conjugation (C) and parity (P) symmetry violating interactions are
derived taking into consideration different ways in which a nucleon interacts
with other nucleons as well as with electrons. Nuclear structure calculations
of the CP-odd nuclear Schiff moment are discussed using the shell model and
other theoretical approaches. Results of the calculations of atomic electric
dipole moments due to the interaction of the nuclear Schiff moment with the
electrons and the P and time-reversal (T) symmetry violating
tensor-pseudotensor electron-nucleus are elucidated using different
relativistic many-body theories. The principles of the measurement of the
electric dipole moments of diamagnetic atoms are outlined. Upper limits for the
nuclear Schiff moment and tensor-pseudotensor coupling constant are obtained
combining the results of atomic experiments and relativistic many-body
theories. The coefficients for the different sources of CP violation have been
estimated at the elementary particle level for all the diamagnetic atoms of
current experimental interest and their implications for physics beyond the
standard model is discussed. Possible improvements of the current results of
the measurements as well as quantum chromodynamics, nuclear and atomic
calculations are suggested.Comment: 46 pages, 19 tables and 16 figures. A review article accepted for
EPJ
Prediction of size distribution of crude oil drops in the permeate using a slotted pore membrane
This paper was accepted for publication in the journal Chemical Engineering Research and Design and the definitive published version is available at http://dx.doi.org/10.1016/j.cherd.2014.02.017Permeate size distribution of various crude oil drops with, and without, oscillating the
membrane has been predicted using the 'Linear Fit' approach. Drops pass through the membrane due to drag force created by the flow of fluid around the drops. Static force is the force responsible for the rejection of drops through the membrane and is directly proportional to the interfacial tension
between dispersed and continuous phases. Without applied shear, 100% cut-off of drops though the membrane is assumed when the drag force and the static force balances each other. With the applied shear, 100% cut-off of drops through the membrane is when drops moves away from the membrane surface due to migration velocities and do not pass the membrane into the permeate. Extrapolating
100% cut-off to the origin of the rejection graphs gives a straight line that is referred as 'Linear Fit' and can be used for predicting rejection below 100% cut-off. Linear fit can be used for predicting drop rejection below 100% cut-off. The portion of oil that would not be rejected by the membrane and would pass through the membrane into the permeate can be calculated using this approach. For a
given size of drops in a feed suspension, permeate size distribution can be predicted by multiplying the fraction of oil passing through the membrane and the feed size distribution data. Overall concentration of oil in the permeate can be calculated by knowing size distribution of drops in the permeate, and that
provides an idea whether the concentration of oil in the permeate is below the standard set by international regulatory authorities
Shear enhanced microfiltration and rejection of crude oil drops through a slotted pore membrane including migration velocities
This article was published in the Journal of Membrane Science [© Elsevier] and the definitive version is available at: http://www.sciencedirect.com/science/article/pii/S0376738812004991Shear enhanced microfiltration of crude oil/water emulsion is investigated and the effect of an applied shear rate on the rejection of droplets by the membrane is reported. Applying vibration provides shear rate at the membrane surface leading to shear-induced migration and an inertial lift of drops/particles. Both phenomena tend to move the droplets away from the membrane surface. The shear-induced migration and inertial lift increase with increasing of the shear rate. A mathematical model is presented to account for the presence of both phenomena. The developed model is used for theoretical prediction of 100% cut-off of crude oil droplets by the membrane with, and with-out, vibration applied. A satisfactory agreement of the model predictions with experimental data shows that the model can be successfully used for a theoretical prediction of 100% cut-off of droplets by slotted pore membranes. Rejection of droplets increased with applying shear rate: at 8000 s-1 shear rate and 200 l m-2 hr-1 flux rate 3 to 4 μm radius droplets were almost completely rejected reducing 400 ppm of crude in the feed to 7 ppm in the permeate
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