Diverse Closed Cavities in Condensed Rare Earth Metal–Chalcogenide Matrixes: Cs[Lu₇Q₁₁] and (ClCs₆)[RE₂₁Q₃₄] (RE = Dy, Ho; Q = S, Se, Te)

Two types of novel ordered chalcogenids Cs­[Lu₇Q₁₁] (Q = S, Se) and (ClCs₆)­[RE₂₁Q₃₄] (RE = Dy, Ho; Q = S, Se, Te) were discovered by high-temperature solid state reactions. The structures were characterized by single-crystal X-ray diffraction data. Cs­[Lu₇Q₁₁] crystallize in the orthorhombic <i>Cmca</i> (no. 64) with <i>a</i> = 15.228(4)–15.849(7) Å, <i>b</i> = 13.357(3)–13.858(6) Å, <i>c</i> = 18.777(5)–19.509(8) Å, and <i>Z</i> = 8. (ClCs₆)­[RE₂₁Q₃₄] crystallize in the monoclinic <i>C</i>2/<i>m</i> (no. 12) with <i>a</i> = 17.127(2)–18.868(2) Å, <i>b</i> = 19.489(2)–21.578(9) Å, <i>c</i> = 12.988(9)–14.356(2) Å, β = 128.604(2)–128.738(4)°, and <i>Z</i> = 2. Both types of compounds feature 3D RE–Q network structures that embed with dual tricapped cubes Cs₂@Se₁₈ in the former or unprecedented matryoshka nesting doll structure cavities of (ClCs₆)@Se₃₂ in the latter. The band gap, band structure, as well as a structure change trend of the majority of A/RE/Q compounds are presented

Dual-Organocatalyst-Promoted Asymmetric Cascade Reaction: Highly Efficient Construction of Enantiopure Fully Substituted Tetrahydro-1,2-oxazines

A four-component asymmetric α-aminoxylation/<i>aza</i>-Michael/Mannich cascade reaction for the construction of fully substituted chiral tetrahydro-1,2-oxazine derivatives was accomplished in high yields with excellent enantio- and diastereoselectivities under mild conditions. The 1,2-oxazine derivative could be transformed to the corresponding multifunctional chiral amino alcohol by N–O cleavage and fused-tricyclic 4-amino-substituted tetra­hydro­quino­lines in good yields with excellent stereoselectivities followed by a Friedel–Crafts reaction. Also a 4-alkoxy-substituted tetra­hydro­quino­line was achieved by C-4 inversion of a 4-amino-substituted tetra­hydro­quino­line

Highly Efficient Asymmetric Synthesis of Enantiopure Dihydro-1,2-oxazines: Dual-Organocatalyst-Promoted Asymmetric Cascade Reaction

A one-pot dual-organocatalyst-promoted asymmetric α-aminoxylation/<i>aza</i>-Michael/aldol consendation cascade reaction is presented. The targeted optically active 1,2-oxazine derivatives are synthesized in moderate yields (up to 70%), excellent enantioselectivities (ee >99% in all cases), and excellent diastereoselectivities (dr up to >99:1) under mild conditions. To further elucidate the synthetic utility of the cascade products, cleavage of the N–O bond is demonstrated and an enantiopure <i>syn</i>-1,4-amino alcohol derivative is achieved in excellent yield

DataSheet_1_The evolution of minimal residual disease: key insights based on a bibliometric visualization analysis from 2002 to 2022.xlsx

BackgroundThe topic of minimal residual disease (MRD) has emerged as a crucial subject matter in the domain of oncology in recent years. The detection and monitoring of MRD have become essential for the diagnosis, treatment, and prognosis of various types of malignancy.AimsThe purpose of this study is to explore the research trends, hotspots, and frontiers of MRD in the last two decades through bibliometric analysis.MethodsWe employed Web of Science databases to carry out a bibliometric visualization analysis of research on 8,913 academic papers about MRD research from 2002 to 2022. VOSviewer, CiteSpace, RStudio, and a bibliometric online analysis platform were mainly used to conduct co-occurrence analysis and cooperative relationship analysis of countries/regions, institutions, journals, and authors in the literature. Furthermore, co-occurrence, co-citation, and burst analyses of keyword and reference were also conducted to generate relevant knowledge maps.ResultsIn the past 20 years, the number of MRD research papers has presented an overall rising trend, going through three stages: a plateau, development, and an explosion. The output of articles in the United States was notably superior and plays a dominant role in this field, and the Netherlands had the highest average citation per article. The most productive and influential institution was the University of Texas MD Anderson Cancer Center. Blood published the most papers and was the most cited journal. A collection of leading academics has come to the fore in the research field, the most prolific of which is Kantarjian HM. It was found that the application of MRD in “acute myeloid leukemia”, “acute lymphoblastic leukemia”, “multiple myeloma”, as well as the detection technology of MRD, are the research hotspots and frontiers in this domain. Furthermore, we analyzed the co-citation network of references and found that the top 10 co-cited references were all associated with MRD in hematological malignancies.ConclusionThis bibliometric visualization analysis conducted a thorough exploration into the research hotspots and trends in MRD from 2002 to 2022. Our findings can aid researchers in recognizing possible collaborations, guiding future research directions, and fostering the growth of MRD detection and monitoring technologies.</p

DataSheet_2_The evolution of minimal residual disease: key insights based on a bibliometric visualization analysis from 2002 to 2022.xlsx

BackgroundThe topic of minimal residual disease (MRD) has emerged as a crucial subject matter in the domain of oncology in recent years. The detection and monitoring of MRD have become essential for the diagnosis, treatment, and prognosis of various types of malignancy.AimsThe purpose of this study is to explore the research trends, hotspots, and frontiers of MRD in the last two decades through bibliometric analysis.MethodsWe employed Web of Science databases to carry out a bibliometric visualization analysis of research on 8,913 academic papers about MRD research from 2002 to 2022. VOSviewer, CiteSpace, RStudio, and a bibliometric online analysis platform were mainly used to conduct co-occurrence analysis and cooperative relationship analysis of countries/regions, institutions, journals, and authors in the literature. Furthermore, co-occurrence, co-citation, and burst analyses of keyword and reference were also conducted to generate relevant knowledge maps.ResultsIn the past 20 years, the number of MRD research papers has presented an overall rising trend, going through three stages: a plateau, development, and an explosion. The output of articles in the United States was notably superior and plays a dominant role in this field, and the Netherlands had the highest average citation per article. The most productive and influential institution was the University of Texas MD Anderson Cancer Center. Blood published the most papers and was the most cited journal. A collection of leading academics has come to the fore in the research field, the most prolific of which is Kantarjian HM. It was found that the application of MRD in “acute myeloid leukemia”, “acute lymphoblastic leukemia”, “multiple myeloma”, as well as the detection technology of MRD, are the research hotspots and frontiers in this domain. Furthermore, we analyzed the co-citation network of references and found that the top 10 co-cited references were all associated with MRD in hematological malignancies.ConclusionThis bibliometric visualization analysis conducted a thorough exploration into the research hotspots and trends in MRD from 2002 to 2022. Our findings can aid researchers in recognizing possible collaborations, guiding future research directions, and fostering the growth of MRD detection and monitoring technologies.</p

Strong Infrared NLO Tellurides with Multifunction: CsX^II₄In₅Te₁₂ (X^II = Mn, Zn, Cd)

Chalcogenides are the most promising mid- and far-infrared materials for nonlinear optical (NLO) applications. Yet, most of them are sulfides and selenides, and tellurides are still rare. Herein, we report three new KCd₄Ga₅S₁₂-structure type NLO-active tellurides, CsX^II₄In₅Te₁₂ (X^II = Mn, Zn, Cd), synthesized by solid-state reactions. The structure features a 3D diamond-like framework constructed by vertex-sharing asymmetric MTe₄ tetrahedra that are stacked along the <i>c</i>-axis. CsCd₄In₅Te₁₂ exhibits the strongest powder second-harmonic generation (SHG) intensity at 2050 nm (0.61 eV) among tellurides to date, 9 × benchmark AgGaS₂ in the range of 46–74 μm particle size. The primary studies reveal the 1.42 eV direct band gap and high absorption coefficient in the visible spectral region for CsCd₄In₅Te₁₂, suggesting it is a new potential solar cell absorber material. In addition, CsMn₄In₅Te₁₂ also displays a spin-canted antiferromagnetic property below 50 K

Image_2_The evolution of minimal residual disease: key insights based on a bibliometric visualization analysis from 2002 to 2022.tif

BackgroundThe topic of minimal residual disease (MRD) has emerged as a crucial subject matter in the domain of oncology in recent years. The detection and monitoring of MRD have become essential for the diagnosis, treatment, and prognosis of various types of malignancy.AimsThe purpose of this study is to explore the research trends, hotspots, and frontiers of MRD in the last two decades through bibliometric analysis.MethodsWe employed Web of Science databases to carry out a bibliometric visualization analysis of research on 8,913 academic papers about MRD research from 2002 to 2022. VOSviewer, CiteSpace, RStudio, and a bibliometric online analysis platform were mainly used to conduct co-occurrence analysis and cooperative relationship analysis of countries/regions, institutions, journals, and authors in the literature. Furthermore, co-occurrence, co-citation, and burst analyses of keyword and reference were also conducted to generate relevant knowledge maps.ResultsIn the past 20 years, the number of MRD research papers has presented an overall rising trend, going through three stages: a plateau, development, and an explosion. The output of articles in the United States was notably superior and plays a dominant role in this field, and the Netherlands had the highest average citation per article. The most productive and influential institution was the University of Texas MD Anderson Cancer Center. Blood published the most papers and was the most cited journal. A collection of leading academics has come to the fore in the research field, the most prolific of which is Kantarjian HM. It was found that the application of MRD in “acute myeloid leukemia”, “acute lymphoblastic leukemia”, “multiple myeloma”, as well as the detection technology of MRD, are the research hotspots and frontiers in this domain. Furthermore, we analyzed the co-citation network of references and found that the top 10 co-cited references were all associated with MRD in hematological malignancies.ConclusionThis bibliometric visualization analysis conducted a thorough exploration into the research hotspots and trends in MRD from 2002 to 2022. Our findings can aid researchers in recognizing possible collaborations, guiding future research directions, and fostering the growth of MRD detection and monitoring technologies.</p

Quaternary Supertetrahedra-Layered Telluride CsMnInTe₃: Why Does This Type of Chalcogenide Tilt?

Dark-red CsMnInTe₃ is synthesized by a solid-state approach using CsCl as the reactive flux. This layered compound is constructed by T₃ supertetrahedra and crystallizes in the space group <i>C</i>2/<i>c</i> with <i>a</i> = 12.400(7) Å, <i>b</i> = 12.400(7) Å, <i>c</i> = 24.32(2) Å, β = 97.31(2)°, and <i>V</i> = 927.07(6) ų. The electrostatic interactions cause tilting of the supertetrahedra layers, and the value of the tilting angle is fixed by a structure index, β′ = 180° – arccos­(<i>a</i>/4<i>c</i>). Such an index is valid for all of the members in this family known to date

DataSheet_3_The evolution of minimal residual disease: key insights based on a bibliometric visualization analysis from 2002 to 2022.xlsx

BackgroundThe topic of minimal residual disease (MRD) has emerged as a crucial subject matter in the domain of oncology in recent years. The detection and monitoring of MRD have become essential for the diagnosis, treatment, and prognosis of various types of malignancy.AimsThe purpose of this study is to explore the research trends, hotspots, and frontiers of MRD in the last two decades through bibliometric analysis.MethodsWe employed Web of Science databases to carry out a bibliometric visualization analysis of research on 8,913 academic papers about MRD research from 2002 to 2022. VOSviewer, CiteSpace, RStudio, and a bibliometric online analysis platform were mainly used to conduct co-occurrence analysis and cooperative relationship analysis of countries/regions, institutions, journals, and authors in the literature. Furthermore, co-occurrence, co-citation, and burst analyses of keyword and reference were also conducted to generate relevant knowledge maps.ResultsIn the past 20 years, the number of MRD research papers has presented an overall rising trend, going through three stages: a plateau, development, and an explosion. The output of articles in the United States was notably superior and plays a dominant role in this field, and the Netherlands had the highest average citation per article. The most productive and influential institution was the University of Texas MD Anderson Cancer Center. Blood published the most papers and was the most cited journal. A collection of leading academics has come to the fore in the research field, the most prolific of which is Kantarjian HM. It was found that the application of MRD in “acute myeloid leukemia”, “acute lymphoblastic leukemia”, “multiple myeloma”, as well as the detection technology of MRD, are the research hotspots and frontiers in this domain. Furthermore, we analyzed the co-citation network of references and found that the top 10 co-cited references were all associated with MRD in hematological malignancies.ConclusionThis bibliometric visualization analysis conducted a thorough exploration into the research hotspots and trends in MRD from 2002 to 2022. Our findings can aid researchers in recognizing possible collaborations, guiding future research directions, and fostering the growth of MRD detection and monitoring technologies.</p

Strong Infrared NLO Tellurides with Multifunction: CsX^II₄In₅Te₁₂ (X^II = Mn, Zn, Cd)

Chalcogenides are the most promising mid- and far-infrared materials for nonlinear optical (NLO) applications. Yet, most of them are sulfides and selenides, and tellurides are still rare. Herein, we report three new KCd₄Ga₅S₁₂-structure type NLO-active tellurides, CsX^II₄In₅Te₁₂ (X^II = Mn, Zn, Cd), synthesized by solid-state reactions. The structure features a 3D diamond-like framework constructed by vertex-sharing asymmetric MTe₄ tetrahedra that are stacked along the <i>c</i>-axis. CsCd₄In₅Te₁₂ exhibits the strongest powder second-harmonic generation (SHG) intensity at 2050 nm (0.61 eV) among tellurides to date, 9 × benchmark AgGaS₂ in the range of 46–74 μm particle size. The primary studies reveal the 1.42 eV direct band gap and high absorption coefficient in the visible spectral region for CsCd₄In₅Te₁₂, suggesting it is a new potential solar cell absorber material. In addition, CsMn₄In₅Te₁₂ also displays a spin-canted antiferromagnetic property below 50 K