28 research outputs found
Efficacy and safety of repeated transcranial magnetic stimulation combined with escitalopram in the treatment of major depressive disorder: a meta-analysis
ObjectiveThis study was designed to systematically review the efficacy and safety of repeated transcranial magnetic stimulation (rTMS) combined with escitalopram in treating major depressive disorder (MDD).MethodsDatabases including PubMed, Embase, Cochrane, Web of Science, CNKI, Wanfang, VIP Journal, and China Biomedical Literature databases were electronically searched for randomized controlled trials of rTMS combined with escitalopram intervention for MDD treatment from the inception of these databases to 27 May 2023. Two reviewers independently screened the studies, extracted the data, and assessed the quality of the included studies. R 4.2.2 was then used for a meta-analysis.ResultsIn total, 19 articles involving 1,032 patients were included. The results of the meta-analysis showed that Hamilton Depression Rating Scale (HAMD) scores were significantly lower in the group receiving rTMS combined with escitalopram (experimental group) than that in the control group [weighted mean difference (WMD) = −5.30, 95% confidence interval (95% CI): −6.44 to −4.17, p < 0.01]. The response rate of the experimental group was significantly higher than that of the control group [odds ratio (OR): 5.48; 95% CI: 3.72 to 8.07; p < 0.01]. No significant difference in the adverse reaction rate was observed between the two groups (OR: 1.04, 95% CI: 0.71 to 1.52, p = 0.82).ConclusionOur findings suggest that rTMS combined with escitalopram can benefit patients with MDD in a safe manner, which may help in guiding clinical practice.Systematic review registrationDOI number: 10.37766/inplasy2023.11.0114, INPLASY2023110114
Recent progress in piezo-phototronics with extended materials, application areas and understanding
A Flexible Wireless sEMG System for Wearable Muscle Strength and Fatigue Monitoring in Real Time
Abstract The detection of surface electromyography (sEMG) signals on the skin has attracted increasing attention because of its ability to monitor muscle conditions in a noninvasive manner and thus possesses great application potential to assess athletic status and training efficiency in real time or to evaluate postoperative muscle rehabilitation conveniently. Here, a flexible wireless sEMG monitoring system that consists of a stretchable sEMG epidermal patch and a flexible printed circuit board to provide real‐time evaluation of muscle strength and fatigue is reported. The epidermal patch is designed to have good stretchability and permeability and optimized to ensure a low contact impedance with the skin and minimized background noise for sEMG signal acquisition with high fidelity. Six commonly used time‐domain and two frequency‐domain features extracted from sEMG signals are systematically analyzed, and a strategy for feature selection and pattern identification is proposed that eventually enables the real‐time assessment of muscle strength and fatigue by using an integrated system in a wearable form
A Tubular Flexible Triboelectric Nanogenerator with a Superhydrophobic Surface for Human Motion Detecting
The triboelectric nanogenerator (TENG) is a newly arisen technology for mechanical energy harvesting from the environment, such as raindrops, wind, tides, and so on. It has attracted widespread attention in flexible electronics to serve as self-powered sensors and energy-harvesting devices because of its flexibility, durability, adaptability, and multi-functionalities. In this work, we fabricated a tubular flexible triboelectric nanogenerator (TF-TENG) with energy harvesting and human motion monitoring capabilities by employing polydimethylsiloxane (PDMS) as construction material, and fluorinated ethylene propylene (FEP) films coated with Cu as the triboelectric layer and electrode, serving in a free-standing mode. The tube structure has excellent stretchability that can be stretched up to 400%. Modifying the FEP films to obtain a superhydrophobic surface, the output performance of TF-TENG was increased by at least 100% compared to an untreated one. Finally, as the output of TF-TENG is sensitive to swing angle and frequency, demonstration of real-time monitoring of human motion state was realized when a TF-TENG was worn on the wrist
Configurable multifunctional integrated circuits based on carbon nanotube dual-material gate devices
10.1039/c8nr08259fNANOSCALE104621857-2186
Hybridizing Triboelectrification and Electromagnetic Induction Effects for High-Efficient Mechanical Energy Harvesting
The recently introduced triboelectric nanogenerator (TENG) and the traditional electromagnetic induction generator (EMIG) are coherently integrated in one structure for energy harvesting and vibration sensing/isolation. The suspended structure is based on two oppositely oriented magnets that are enclosed by hollow cubes surrounded with coils, which oscillates in response to external disturbance and harvests mechanical energy simultaneously from triboelectrification and electromagnetic induction. It extends the previous definition of hybrid cell to harvest the same type of energy with multiple approaches. Both the sliding-mode TENG and contact-mode TENG can be achieved in the same structure. In order to make the TENG and EMIG work together, transformers are used to match the output impedance between these two power sources with very different characteristics. The maximum output power of 7.7 and 1.9 mW on the same load of 5 kΩ was obtained for the TENG and EMIG, respectively, after impedance matching. Benefiting from the rational design, the output signal from the TENG and the EMIG are in phase. They can be added up directly to get an output voltage of 4.6 V and an output current of 2.2 mA in parallel connection. A power management circuit was connected to the hybrid cell, and a regulated voltage of 3.3 V with constant current was achieved. For the first time, a logic operation was carried out on a half-adder circuit by using the hybrid cell working as both the power source and the input digit signals. We also demonstrated that the hybrid cell can serve as a vibration isolator. Further applications as vibration dampers, triggers, and sensors are all promising
Quantitative study on the effect of surface treatments on the electric characteristics of ZnO nanowires
Treatment of ZnO nanowires (NWs) using hydrogen peroxide with increasing concentration results in a continuous increase in the amount of -OH group at the surfaces of the NWs, which demonstrates different characteristics in the transport behaviors of the NWs. Combined with results from theoretical simulation and microphotoluminescence, the variation in the nanowire transport property is explained by the change of carrier density and mobility as induced by the surface treatment. © 2008 American Chemical Society
Triboelectric Nanogenerator Built on Suspended 3D Spiral Structure as Vibration and Positioning Sensor and Wave Energy Harvester
An unstable mechanical structure that can self-balance when perturbed is a superior choice for vibration energy harvesting and vibration detection. In this work, a suspended 3D spiral structure is integrated with a triboelectric nanogenerator (TENG) for energy harvesting and sensor applications. The newly designed vertical contact–separation mode TENG has a wide working bandwidth of 30 Hz in low-frequency range with a maximum output power density of 2.76 W/m<sup>2</sup> on a load of 6 MΩ. The position of an in-plane vibration source was identified by placing TENGs at multiple positions as multichannel, self-powered active sensors, and the location of the vibration source was determined with an error less than 6%. The magnitude of the vibration is also measured by the output voltage and current signal of the TENG. By integrating the TENG inside a buoy ball, wave energy harvesting at water surface has been demonstrated and used for lighting illumination light, which shows great potential applications in marine science and environmental/infrastructure monitoring
Performance Boosting of Flexible ZnO UV Sensors with Rational Designed Absorbing Antireflection Layer and Humectant Encapsulation
Flexible
ZnO thin film UV sensors with 3 orders of magnitude improvement
in sensitivity and 2 orders of magnitude acceleration in speed are
realized via light absorption efficiency enhancement and surface encapsulation.
Devices are constructed on polyethylene substrate incorporating morphology
controlled ZnO nanorod arrays (NRAs) as absorbing antireflection layers.
By adjusting the morphology of ZnO NRAs, the light absorptance exceeds
99% through effectively trapping incident photons. As a result, the
sensitivity of the UV sensor reaches 109 000. Moreover, a mechanism
of competitive chemisorption between O<sub>2</sub> and H<sub>2</sub>O at oxygen vacancy sites is proposed to explain the phenomenon of
the speed acceleration in moist environment. A new approach of humectant
encapsulation is used to make H<sub>2</sub>O participant rapid processes
dominant for speed acceleration. Two orders of magnitude speed enhancement
in reset time is achieved by polyethylene glycol encapsulation. After
a total 3000 cycles bending test, the decay in the responsivity of
UV sensor is within 20%, indicating good mechanical stability. All
these results not only demonstrate a simple, effective and scalable
approach to fabricate high sensitive and fast response flexible ZnO
UV sensors, but also provide meaningful references for performance
boosting of photoelectronic devices based on other oxide semiconductors