Development of a portable mechanical hysteresis measurement and imaging system for impact characterization in honeycomb sandwich structures

Honeycomb sandwich materials are commonly used for aero‐structures, but because the outer skins are typically thin, 2–10 plys, the structures are susceptible to impact damage. NDI methods such as tap tests, bond testers and TTU ultrasound are successfully deployed to find impact damage, but identifying the type∕degree of damage is troublesome. As the type∕degree of impact damage guides decisions by the maintenance, repair and overhaul (MRO) community regarding repair, the ability to characterize impacts is of interest. Previous work demonstrated that additional impact characterization may be gleaned from hysteresis loop area, as determined from an out‐of‐plane load‐vs‐displacement plot, where this parameter shows a correlation with impact energy. This presentation reports on current work involving the development of a portable hysteresis measurement and imaging system based on an instrumented tapper. Data processing and analysis methods that allow production of the load∕displacement data from a single accelerometer are discussed, with additional reporting of tests of software to automatically vary pixel size during scanning to decrease C‐scans inspection time

Field and Beta-Site Testing of the Dripless Bubbler Ultrasonic Scanner

The Dripless Bubbler technique [1–4] has demonstrated in both laboratory and field trials the ability to identify adhesive disbonds and quantify the metal loss due to corrosion in aircraft fuselage structures. In the latest round of field trials, this technique was successfully applied to aid in characterizing exfoliation corrosion around fasteners in thick wing skins (0.190 – 0.500 inches). In two Beta-site tests, the technique was used to identify delaminations, verify ply drop-offs and evaluate repairs in aircraft composite structures such as rudders, spoilers and flaps

Unbiased estimators for random design regression

In linear regression we wish to estimate the optimum linear least squares predictor for a distribution over d-dimensional input points and real-valued responses, based on a small sample. Under standard random design analysis, where the sample is drawn i.i.d. from the input distribution, the least squares solution for that sample can be viewed as the natural estimator of the optimum. Unfortunately, this estimator almost always incurs an undesirable bias coming from the randomness of the input points. In this paper we show that it is possible to draw a non-i.i.d. sample of input points such that, regardless of the response model, the least squares solution is an unbiased estimator of the optimum. Moreover, this sample can be produced efficiently by augmenting a previously drawn i.i.d. sample with an additional set of d points drawn jointly from the input distribution rescaled by the squared volume spanned by the points. Motivated by this, we develop a theoretical framework for studying volume-rescaled sampling, and in the process prove a number of new matrix expectation identities. We use them to show that for any input distribution and $\epsilon>0$ there is a random design consisting of $O(d\log d+ d/\epsilon)$ points from which an unbiased estimator can be constructed whose square loss over the entire distribution is with high probability bounded by $1+\epsilon$ times the loss of the optimum. We provide efficient algorithms for generating such unbiased estimators in a number of practical settings and support our claims experimentally

Galectin-3 regulates intracellular trafficking of EGFR through Alix and promotes keratinocyte migration.

The EGFR-mediated signaling pathways are important in a variety of cellular processes, including cell migration and wound re-epithelialization. Intracellular trafficking of EGFR is critical for maintaining EGFR surface expression. Galectin-3, a member of an animal lectin family, has been implicated in a number of physiological and pathological processes. Through studies of galectin-3-deficient mice and cells isolated from these mice, we demonstrated that the absence of galectin-3 impairs keratinocyte migration and skin wound re-epithelialization. We have linked this pro-migratory function to a crucial role of cytosolic galectin-3 in controlling intracellular trafficking and cell surface expression of EGFR after EGF stimulation. Without galectin-3, the surface levels of EGFR are markedly reduced, and the receptor accumulates diffusely in the cytoplasm. This is associated with reduced rates of both endocytosis and recycling of the receptor. We have provided evidence that this previously unreported function of galectin-3 may be mediated through interaction with its binding partner Alix, which is a protein component of the ESCRT (endosomal sorting complex required for transport) machinery. Our results suggest that galectin-3 is potentially a critical regulator of a number of important cellular responses through its intracellular control of trafficking of cell surface receptors

Bony ingrowth potential of 3D-printed porous titanium alloy: a direct comparison of interbody cage materials in an in vivo ovine lumbar fusion model.

Background contextThere is significant variability in the materials commonly used for interbody cages in spine surgery. It is theorized that three-dimensional (3D)-printed interbody cages using porous titanium material can provide more consistent bone ingrowth and biological fixation.PurposeThe purpose of this study was to provide an evidence-based approach to decision-making regarding interbody materials for spinal fusion.Study designA comparative animal study was performed.MethodsA skeletally mature ovine lumbar fusion model was used for this study. Interbody fusions were performed at L2-L3 and L4-L5 in 27 mature sheep using three different interbody cages (ie, polyetheretherketone [PEEK], plasma sprayed porous titanium-coated PEEK [PSP], and 3D-printed porous titanium alloy cage [PTA]). Non-destructive kinematic testing was performed in the three primary directions of motion. The specimens were then analyzed using micro-computed tomography (µ-CT); quantitative measures of the bony fusion were performed. Histomorphometric analyses were also performed in the sagittal plane through the interbody device. Outcome parameters were compared between cage designs and time points.ResultsFlexion-extension range of motion (ROM) was statistically reduced for the PTA group compared with the PEEK cages at 16 weeks (p-value=.02). Only the PTA cages demonstrated a statistically significant decrease in ROM and increase in stiffness across all three loading directions between the 8-week and 16-week sacrifice time points (p-value≤.01). Micro-CT data demonstrated significantly greater total bone volume within the graft window for the PTA cages at both 8 weeks and 16 weeks compared with the PEEK cages (p-value<.01).ConclusionsA direct comparison of interbody implants demonstrates significant and measurable differences in biomechanical, µ-CT, and histologic performance in an ovine model. The 3D-printed porous titanium interbody cage resulted in statistically significant reductions in ROM, increases in the bone ingrowth profile, as well as average construct stiffness compared with PEEK and PSP

Field and Beta-Site Testing of the Dripless Bubbler Ultrasonic Scanner

The Dripless Bubbler technique [1-4] has demonstrated in both laboratory and field trials the ability to identify adhesive disbonds and quantify the metal loss due to corrosion in aircraft fuselage structures. In the latest round of field trials, this technique was successfully applied to aid in characterizing exfoliation corrosion around fasteners in thick wing skins (0.190- 0.500 inches). In two Beta-site tests, the techniqu

An exploration of the utilities of terahertz waves for the NDE of composites

We report an investigation of terahertz waves for the nondestructive evaluation of composite materials and structures. The modalities of the terahertz radiation used were time domain spectroscopy (TDS) and continuous wave (CW). The composite materials and structures investigated include both non‐conducting polymeric composites and carbon fiber composites. Terahertz signals in the TDS mode resembles that of ultrasound; however, unlike ultrasound, a terahertz pulse can detect a crack hidden behind a larger crack. This was demonstrated in thick GFRP laminates containing double saw slots. In carbon composites the penetration of terahertz waves is quite limited and the detection of flaws is strongly affected by the angle between the electric field vector of the terahertz waves and the intervening fiber directions. The structures tested in this study include both solid laminates and honeycomb sandwiches. The defects and anomalies investigated by terahertz waves were foreign material inclusions, simulated disbond and delamination, mechanical impact damage, heat damage, and water or hydraulic fluid ingression. The effectiveness and limitations of terahertz radiation for the NDE of composites are discussed