97 research outputs found
A review of English consonantal phonology for high school English teachers in Taiwan
- Author
- Publication venue
- Kansas State University
- Publication date
- 01/01/1971
- Field of study
Factors affecting the prevalence of strongly and weakly carcinogenic and lower-risk human papillomaviruses in anal specimens in a cohort of men who have sex with men (MSM)
- Author
- A Nyitray
- AG Nyitray
- AG Nyitray
- AR Giuliano
- AR Giuliano
- Clive M. Gray
- CM Nielson
- D Forman
- Dorothy J. Wiley
- EC Seaberg
- EF Dunne
- EP Simard
- Eric C. Seaberg
- F Coutlee
- G D’Souza
- G Zou
- GM Clifford
- GM Clifford
- GM Clifford
- Gypsyamber D’Souza
- H Minkoff
- Hilary Hsu
- IU Park
- JM Palefsky
- K Kim
- K Ozasa
- Katherine DeAzambuja
- Kristofer Chua
- L Licitra
- M Dosemeci
- M Melbye
- M Schiffman
- MC Bell
- MG Dona
- MP Stevens
- MS Shiels
- MS Shiels
- N Keita
- O Aynaud
- Otoniel Martínez-Maza
- P Patel
- PE Gravitt
- PE Gravitt
- PE Gravitt
- PV Chin-Hong
- PV Chin-Hong
- R Detels
- R Detels
- RA Kaslow
- Roger Detels
- Ross D. Cranston
- S Goldstone
- Shehnaz K. Hussain
- Stephen Young
- V Bouvard
- WM Christopherson
- Xiuhong Li
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- 20/11/2013
- Field of study
Background: MSM are at higher risk for invasive anal cancer. Twelve human papillomaviruses (HPVs) cause cervical cancer in women (Group 1 high-risk HPVs (hrHPVs)) and 13 HPVs are probable/possible causes (Group 2 hrHPVs) of cervical malignancy. HPVs rarely associated with malignancy are classified as lower-risk HPVs (lrHPVs). Materials and Methods: Dacron-swab anal-cytology specimens were collected from and data complete for 97% (1262/1296) of Multicenter AIDS Cohort Study (MACS) men tested for HPVs using the Linear Array assay. Multivariate Poisson regression analyses estimated adjusted prevalence ratios for Group 1/2 hrHPVs and lrHPVs, controlling for the effects of age, race, ethnicity, sexual partnerships, smoking; HIV-infection characteristics, treatment, and immune status among HIV-infected men. Results: HIV-infected men showed 35-90% higher prevalence of Group 1/2 hrHPVs and lrHPVs than HIV-uninfected men, and higher prevalence of multi-Type, and multiple risk-group infections. CD4+ T-cell count was inversely associated with HPV Group 2 prevalence (p<0.0001). The number of receptive anal intercourse (RAI) partners reported in the 24 months preceding HPV testing predicted higher prevalence of Group 1/2 hrHPVs. Men reporting ≥30 lifetime male sex partners before their first MACS visit and men reporting ≥1 RAI partners during the 24 months before HPV testing showed 17-24% and 13-17% higher prevalence of lrHPVs (p-values ≤0.05). Men reporting smoking between MACS visit 1 and 24 months before HPV testing showed 1.2-fold higher prevalence of Group 2 hrHPVs (p = 0.03). Both complete adherence to CART (p = 0.02) and HIV load <50 copies/mL (p = 0.04) were protective for Group 1 hrHPVs among HIV-infected men. Conclusions: HIV-infected men more often show multi-type and multi-group HPV infections HIV-uninfected men. Long-term mutual monogamy and smoking cessation, generally, and CART-adherence that promotes (HIV) viremia control and prevents immunosuppression, specifically among HIV-infected MSM, are important prevention strategies for HPV infections that are relevant to anal cancer. © 2013 Wiley et al
Na+/K+-ATPase α1 Identified as an Abundant Protein in the Blood-Labyrinth Barrier That Plays an Essential Role in the Barrier Integrity
- Author
- A Motoyama
- A Seth
- Aernout Luttun
- AK Rajasekaran
- AL Nuttall
- Alfred L. Nuttall
- AR Calabria
- CG Le Prell
- CJ Hsu
- DJ Munoz
- DW Lin
- E Durr
- F Cornelius
- G Pottiez
- GE Shull
- GE Shull
- H Liu
- HM Eisenberg
- Irina Omelchenko
- J Tian
- JC Skou
- JC Skou
- JD Huber
- John E. Klimek
- JP Morth
- K Doi
- K Geering
- K Hirose
- K Lamm
- KK Ohlemiller
- Larry L. David
- LD Fechter
- LH Stockwin
- M Cohen-Salmon
- M Klein
- M Suzuki
- MA Gratton
- MA Gratton
- MC Liberman
- MI Violette
- Min Dai
- MW Musch
- NS Harhaj
- PA Santi
- PA Wilmarth
- Peter G. Gillespie
- Phillip A. Wilmarth
- RE Clifford
- RO Stuart
- S Muto
- S Osada
- S Takeuchi
- SA Rajasekaran
- SA Rajasekaran
- SB Minami
- SK Juhn
- SK Juhn
- SL McFadden
- T Suzuki
- Teresa M. Wilson
- WJ Betz
- X Shi
- Xiaorui Shi
- YH Chen
- Yue Yang
- Z Xie
- Publication venue
- Public Library of Science
- Publication date
- 01/01/2011
- Field of study
BACKGROUND:The endothelial-blood/tissue barrier is critical for maintaining tissue homeostasis. The ear harbors a unique endothelial-blood/tissue barrier which we term "blood-labyrinth-barrier". This barrier is critical for maintaining inner ear homeostasis. Disruption of the blood-labyrinth-barrier is closely associated with a number of hearing disorders. Many proteins of the blood-brain-barrier and blood-retinal-barrier have been identified, leading to significant advances in understanding their tissue specific functions. In contrast, capillaries in the ear are small in volume and anatomically complex. This presents a challenge for protein analysis studies, which has resulted in limited knowledge of the molecular and functional components of the blood-labyrinth-barrier. In this study, we developed a novel method for isolation of the stria vascularis capillary from CBA/CaJ mouse cochlea and provided the first database of protein components in the blood-labyrinth barrier as well as evidence that the interaction of Na(+)/K(+)-ATPase α1 (ATP1A1) with protein kinase C eta (PKCη) and occludin is one of the mechanisms of loud sound-induced vascular permeability increase. METHODOLOGY/PRINCIPAL FINDINGS:Using a mass-spectrometry, shotgun-proteomics approach combined with a novel "sandwich-dissociation" method, more than 600 proteins from isolated stria vascularis capillaries were identified from adult CBA/CaJ mouse cochlea. The ion transporter ATP1A1 was the most abundant protein in the blood-labyrinth barrier. Pharmacological inhibition of ATP1A1 activity resulted in hyperphosphorylation of tight junction proteins such as occludin which increased the blood-labyrinth-barrier permeability. PKCη directly interacted with ATP1A1 and was an essential mediator of ATP1A1-initiated occludin phosphorylation. Moreover, this identified signaling pathway was involved in the breakdown of the blood-labyrinth-barrier resulting from loud sound trauma. CONCLUSIONS/SIGNIFICANCE:The results presented here provide a novel method for capillary isolation from the inner ear and the first database on protein components in the blood-labyrinth-barrier. Additionally, we found that ATP1A1 interaction with PKCη and occludin was involved in the integrity of the blood-labyrinth-barrier
Abstracts of presentations on plant protection issues at the xth international congress of virology: August 11-16,1996 Binyanei haOoma, Jerusalem, Israel Part 2 Plenary Lectures
- Author
- Abo-El-Saad Sh
- AbouHaidar M.
- AbouHaidar M.
- Aboul-Ata A.
- Aboul-Ata A.
- Adam G.
- Adams M.
- Albouy J.
- Aliskevicius E.
- Almási A.
- Angel-Diaz J.
- Antoniw J.
- Arce-Johnson Patricio
- Arntzen C.
- Arroyo R.
- Astier S.
- Atabekov J.
- Atanassov A.
- Atiri G.
- Aulik M.
- Bachelier J.
- Bachelier J.
- Badge J.
- Badge J.
- Banerjee N.
- Barba M.
- Barrón B.
- Bateson M.
- Bateson M.
- Baulcombe D.
- Baulcombe David
- Beachy R.
- Beachy Roger
- Becker D.
- Berger P.
- Bishnoi S.
- Bishop D.
- Bitoova M.
- Blaise F.
- Bodegom P.
- Bol J.
- Bol John
- Boulton M.
- Brunt A.
- Brunt A.
- Brzin Joze
- Böddi B.
- Callahan A.
- Candresse T.
- Cardol Erwin
- Carney Kim
- Carrier Karma
- Carrington James
- Carson R.
- Cassidy Brandt
- Chachulska A.
- Chaleeprom W.
- Chatel H.
- Chen Gang
- Chen L.
- Chiang A.
- Chiang Chu-Hui
- Christensen F.
- Christou P.
- Chrzanowska M.
- Chu P.
- Chu Paul
- Chupeau Y.
- Clifford T.
- Cohen S.
- Collins N.
- Corsten Sandra
- Dagless E.
- Dale J.
- Dale J.
- Dale J.
- Dale J.
- Daròs J.
- Davenport G.
- Davies J.
- De Haan P.
- de Haan Peter
- de Kochko A.
- De Rover A.
- Deiman B.
- Denisenko O.
- Dinant S.
- Ding S.
- DiSerio F.
- Drossard J.
- Druka Amis
- Duan Y.
- Dunez J.
- Dunez J.
- Dunez J.
- Dwyer G.
- Edelbaum Orit
- Ekes M.
- El-Hariry M.
- El-Saied M.
- English J.
- Faktor O.
- Falk B.
- Fauquet C.
- Faure J.
- Fedorkin O.
- Feldman J.
- Fischer R.
- Flasinski Stanislaw
- Floras R.
- Ford C.
- Fortin Marc
- Foster G.
- Foster G.
- Foster G.
- Foster G.
- Frenkel M.
- Fuchs E.
- Fütterer Johannes
- Gaba V.
- Gaborianvi R.
- Gahakwa D.
- Gal-On A.
- Gal-On A.
- Garcia-Arenal F.
- García-Luque I.
- Gellatly D.
- Gielen J.
- Gilardi P.
- Gilbertson R.
- Goldbach R.
- Goldbach Rob
- Goldbach Rob
- Golshani A.
- Gonsalves Dennis
- Graichen K.
- Gruden Kristina
- Guelemerov S.
- Hafner G.
- Hajimorad M.
- Ham E.
- Handley J.
- Hansen J.
- Hardi V.
- Harding R.
- Harding R.
- Harding R.
- Hellwald K.
- Hernádez A.
- Hiebert E.
- Higgins T.
- Hohn Thomas
- Hou Y.
- Hsu Yau-Heiu
- Huet H.
- Huguenot Claire
- Hull Roger
- Hwang D.
- Hwang Duk-Ju
- Ikegami M.
- Ivanov I.
- Ivanova Lidia
- Jacquet C.
- Jan Fuh-Jyh
- Johnson J.
- Jones M.
- Kageyama Y.
- Kaniewski W.
- Kaniewski W.
- Kaplan I.
- Karamagioli M.
- Kashiwazaki S.
- Kasschau Kristin
- Kawashima H.
- Kelve M.
- Kiguchi T.
- Kikkert M.
- Kinta M.
- Koenen A.
- Kominek P.
- Kormelink R.
- Kormelink Richard
- Kregar Igor
- Kuittinen T.
- Kunhara J.
- Kusiak C.
- Kusume T.
- Kuznetsova L.
- Laliberté J.
- Lapidot Moshe
- Larkin Phil
- Lawson E.
- Le Gall O.
- Leech M.
- Lento K.
- Levine B.
- Levy L.
- Li D.
- Li Q.
- Li W.
- Lin Biing-Yuan
- Lin Na-Sheng
- Lin T.
- Linthorst Huub
- Livneh O.
- Lock S.
- Lodhi G.
- Lomonossoff G.
- Loo H.
- Lot H.
- López L.
- MacFarlane S.
- Maganja Darja
- Makhdoom Rahat
- Maki-Valkama T.
- Makinen K.
- Makkouk K.
- Marano Maria-Rosa
- Marshall D.
- Martínez-Zapater J.
- Mathews A.
- Maugeri M.
- May G.
- Mayo M.
- Mazithulela G.
- McCarthy P.
- Mehlo L.
- Meiri E.
- Merits A.
- Mikhailov M.
- Miller W.
- Mitsky T.
- Mooney A.
- Morozov S.
- Mueller E.
- Murayama A.
- Nahring J.
- Natsuaki T.
- Nigul L.
- Nikolaeva Velitchka
- Oertel U.
- Ong C.
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- Oukropec I.
- Pallas V.
- Paltridge N.
- Palukaitis P.
- Palukaitis P.
- Pang Sheng-Zhi
- Passmore B.
- Pehu E.
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- Phillips S.
- Pilowsky M.
- Plante Daniel
- Pleij C.
- Polák J.
- Ponz F.
- Porta C.
- Porter J.
- Powell C.
- Prins Marcel
- Prins Marcel
- Prody G.
- Purcifull D.
- Quemada Hector
- Rabenstein F.
- Raccah B.
- Ragozzino A.
- Ramirez E.
- Rasochova L.
- Ratcliff Frank
- Rathjen J.
- Ravelonandro M.
- Ravelonandro M.
- Ravnikar Maja
- Revere F.
- Rishi Narayan
- Rivera-Bustamante Rafael
- Robaglia C.
- Robinson D.
- Robinson D.
- Rodoni B.
- Rodriguez-Alvarado G.
- Romero A.
- Roossinck M.
- Rothnie Helen
- Roy P.
- Ruiz-Perez T.
- Ryu K.
- Saarma M.
- Saarma M.
- Saarma M.
- Saito M.
- Salem G.
- Sanchez-Navarro J.
- Sanders R.
- Sanfacon Helene
- Sangwan R.
- Satour M.
- Schillberg S.
- Schubert J.
- Schubert J.
- Schumann D.
- Scorza R.
- Seal S.
- Sela I.
- Sela L.
- Serra M.
- Shams-Bakhsh M.
- Shi B.
- Shiel P.
- Shukla D.
- Sijen Titia
- Sithisarn-Burns P.
- Sivamani E.
- Smith G.
- Smith G.
- Soliman N.
- Somsap V.
- Soto M.
- Souche S.
- Spall V.
- Storms M.
- Stram Y.
- Stratford R.
- Sugimura N.
- Symons R.
- Symons R.
- Szigeti Z.
- Tabe L.
- Taliansky M.
- Tamada T.
- Tamm T.
- Taylor K.
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- Taylor S.
- Thole V.
- Thouvenel J.
- Tomaru K.
- Tomassoli L.
- Tricoli David
- Truve E.
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- Tsuda S.
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- Turner Nilgun
- Turner R.
- Twell D.
- Uchino H.
- Ursin V.
- Valkonen J.
- Valkonen J.
- Van Grinsven M.
- van Kammen Ab
- van Lent J.
- van Oers Monique
- Van Schepen A.
- Vardi E.
- Walter J.
- Wang Aiming
- Wang Ching-Hsien
- Ward C.
- Wellink Joan
- Wesley Varsha
- Wieczorek Andrew
- Wittmann S.
- Wolf D.
- Wurscher M.
- Wyatt S.
- Wylie S.
- Xiao X.
- Yang S.
- Yankulova Margarita
- Yeh Shyi-Dong
- Yitang Yan
- Zagórski W.
- Zaitlin M.
- Zalewski J.
- Zeituny Silvy
- Zelcer A.
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- Zimmermann S.
- Štrukelj Borut
- Publication venue
- Publication date
- 18/06/2018
- Field of study
ICAR: endoscopic skull‐base surgery
- Author
- Aaron G
- Aaron GP
- Abergel A
- Abouaf L
- Abrishamkar S
- Acioly MA
- Acioly MA
- Acuna RT
- Adams AS
- Adappa ND
- Aferzon M
- Agaimy A
- Agarwal A
- Aggarwal A
- Agrawal D
- Ahmed OH
- Aihara M
- Akagami R
- Alahmadi H
- Albu S
- Albu S
- Albu S
- Alexander A
- Alimohamadi M
- Almefty R
- Almeida JR
- Almeida JR
- Almeida JR
- Almeida JR
- Almeida JR
- Almeida JR
- Almeida JR
- Almond MC
- Alobaid A
- Alobid I
- Alobid I
- Alos L
- AlQahtani A
- Altay T
- Alvarez FL
- Alves MV
- Al‐Mamgani A
- Al‐Mefty O
- Al‐Sheibani S
- Amano K
- Amdur RJ
- Amelot A
- American Academy of Pediatrics Steering Committee on Quality Improvement and Management
- Amichetti M
- Amin SM
- Amit M
- Amit M
- Amit M
- Ammirati M
- Anari S
- Anderson D
- Anderson RL
- Andrade NA
- Andrews JC
- Anik I
- Ansa B
- Ansari M
- Antonelli AR
- Arafah BM
- Arafah BM
- Arafah BM.
- Arai A
- Arat YO
- Arbolay OL
- Ardehali MM
- Armengot M
- Arnautovic KI
- Arrer E
- Arslan HH
- Aryan HE
- Asano S
- Askoxylakis V
- Astrup J
- Awad AJ
- Awad M
- Azad TD
- Aziz KM
- Babin E
- Bachmann G
- Back L
- Backlund EO.
- Baijal V
- Balaker AE
- Ballah D
- Balzer JR
- Banks CA
- Banu MA
- Banu MA
- Banuchi VE
- Barnes L
- Baser B
- Baskin DS
- Battaglia P
- Battaglia P
- Becker AM
- Beckhardt RN
- Bedi AD
- Bedrosian JC
- Bedrosian JC
- Beer‐Furlan A
- Beer‐Furlan A
- Beham A
- Bejjani GK
- Bell D
- Bell RB
- Bell RB
- Berdahl JP
- Berhouma M
- Berker M
- Berker M
- Berkmann S
- Berkmann S
- Berkmann S
- Bernal‐Sprekelsen M
- Bernal‐Sprekelsen M
- Bernat AL
- Bertrand B
- Bhasker S
- Bhatti SN
- Bidot S
- Bills DC
- Bishop JA
- Biswas D
- Black PM
- Bleier BS
- Bleier BS
- Bleier BS
- Bleier BS
- Bleier BS
- Bloch C
- Bloch O
- Bly RA
- Boghani Z
- Bohman LE
- Bohman LE
- Bokhari AR
- Boling CC
- Bolzoni Villaret A
- Borg A
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- Boukheris H
- Brackmann DE
- Bradley PJ
- Branston NM
- Brastianos PK
- Bremer JW
- Bresson D
- Briet C
- Briggs RJ
- Brodie HA.
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- Brunworth J
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- Bunin GR
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- But‐Hadzic J
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- Caicedo‐Granados E
- Caldarelli M
- Campbell E
- Campbell PG
- Campbell RG
- Capatina C
- Cappabianca P
- Cappabianca P
- Cappabianca P
- Cappabianca P
- Cappabianca P
- Cappabianca P
- Carlson ML
- Carmel P
- Carrau RL
- Carrillo JF
- Carter KB
- Carvalho P
- Cassano M
- Castelnuovo P
- Castelnuovo P
- Castelnuovo P
- Catapano G
- Cathelinaud O
- Cavalheiro S
- Cavallo LM
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- Cavallo LM
- Cavallo LM
- Cebula H
- Ceylan S
- Ceylan S
- Ceylan S
- Chaaban MR
- Chaaban MR
- Chaaban MR
- Chaaban MR
- Chabot JD
- Chabot JD
- Chan JY
- Chan KH
- Chandler JR
- Chandra RK
- Chanson P
- Chapman PR
- Chapurlat RD
- Charlett SD
- Chauvet D
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- Chen AM
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- Chi F
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- Chibbaro S
- Chin CJ
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- Chiou SM
- Chiu AG
- Cho DY
- Cho JM
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- Choby GW
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- Chowdhury FH
- Christopherson K
- Chung TK
- Chung WY
- Ciporen JN
- Ciric I
- Ciric I
- Clark AJ
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- Clemenza JW
- Clifford‐Jones RE
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- Eljamel MS.
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- Erdem E
- Eseonu CI
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- Fatemi N
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- Felippu A
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- Fernandes Cabral DT
- Fernandez‐Miranda JC
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- Fitzek MM
- Flannery TJ
- Fleischman GM
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- Fleseriu M
- Folbe AJ
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- Frazee RC
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- Friedman JA
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- Frierson HF
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- Fujii K
- Fujita Y
- Fukuda M
- Fyrmpas G
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- Gallagher KK
- Gallagher MJ
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- Gardner PA
- Gardner PA
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- Gelbard A
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- Gilat H
- Giustina A
- Glicksman JT
- Godoy MD
- Goel A
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- Gompel JJ
- Gondim JA
- Gondim JA
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- Gorelick J
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- Goudakos JK
- Gousias K
- Graffeo CS
- Gray ST
- Grayson JW
- Greig SR
- Griffith AJ
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- Wiseman SM
- Witte O
- Wong EHC
- Wood JW
- Woodworth BA
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- Wormald PJ
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- Xie L
- Xie T
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- Xiong L
- Xu CC
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- Yan CH
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- Yano S
- Yano S
- Yao WC
- Yasargil MG
- Yasargil MG
- Yasargil MG
- Ye L
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- Yilmazlar S
- Yin ZZ
- Yin ZZ
- Yiotakis I
- Yonezawa K
- Yoo F
- Yoshida E
- Yoshizaki T
- You R
- Youssef AS
- Youssef S
- Yunoue S
- Yu‐Wai‐Man P
- Zacharia BE
- Zada G
- Zaidi HA
- Zanation AM
- Zanation AM
- Zanation AM
- Zanation AM
- Zanation AM
- Zhan R
- Zhang C
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- Zhang HK
- Zhang L
- Zhang M
- Zhang Q
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- Zuccaro G.
- Zuniga MG
- Zwagerman NT
- Publication venue
- Publication date
- 01/07/2019
- Field of study
n/
The Changing Landscape for Stroke\ua0Prevention in AF: Findings From the GLORIA-AF Registry Phase 2
- Author
- Abban Dzifa
- Abdul Nasser
- Abelson Mark
- Ackermann Alan
- Adams Fran
- Adams Luthando
- Adrag\ue3o Pedro
- Ageno Walter
- Aggarwal Rajesh
- Agosti Sergio
- Aguilar Linares Julio Alberto
- Aguilar Francisco
- Aguinaga Luis
- Ahmad Zia
- Ainsworth Paul
- Al Dallow Raed
- Al Ghalayini Kamal
- Al Ismail Saad
- Al Joundi Tammam
- Al Mahameed Soufian
- Al Obaidi Mohamed
- Al Zoebi Ayham
- Alasfar Abdelfatah
- Alawwa Abdul
- Alderson Lisa
- Alexopoulos Dimitrios
- Ali Abdullah
- Ali Malik
- Aliyar Pareed
- Almassi Hossein
- Almuti Khalid
- Alshehri Mohamed
- Altmann Ute
- Alves Alvaro Rabelo
- Amara Walid
- Amelot Mathieu
- Amjadi Nima
- Ammirati Fabrizio
- Andrawis Nabil
- Angela Koh Su Mei
- Angoulvant Denis
- Annoni Giorgio
- Ansalone Gerardo
- Antonescu Sorin Alexandru
- Ariani Mehrdad
- Arias Juan Carlos
- Armero S\ue9bastien
- Arora Chander
- Arora Rohit
- Ashcraft William
- Aslam M. Shakil
- Astesiano Alfredo
- Audouin Philippe
- Augenbraun Charles
- Aydin S.
- Azar Rabih
- Azim Abul
- Aziz Shahid
- B\uf8hmer Ellen
- Backes Luciano Marcelo
- Baig Mirza
- Bains Suchdeep
- Bakbak Asaad
- Baker Seth
- Bakhtiar Karim
- Bala Richard
- Banayan Jonathan
- Bandh Stellan
- Bando Shigenobu
- Banerjee Subhash
- Bank Alan
- Bar\uf3n Gonzalo
- Barbarash Olga
- Barr Craig
- Barrera Carlos
- Bartels Dorothee B.
- Barton John
- Baula Giovanni
- Bayeh Hamid
- Bazargani Nooshin
- Behrens Steffen
- Bell Alan
- Benezet Mazuecos Juan
- Benhalima Bouziane
- Berdagu\ue9 Philippe
- Berg van den B. J.
- Bergen van P. F. M. M.
- Berngard Edvard
- Bernstein Richard
- Berrospi Percy
- Berti Sergio
- Bertomeu Vicente
- Berz Andrea
- Bettencourt Paulo
- Betzu Robert
- Beyer Westendorf Jan
- Bhagwat Ravi
- Black Toby
- Blanco Ibaceta Jorge Hugo
- Bloom Stephen
- Blumberg Edwin
- Bo Mario
- Bockisch Valerie
- Bongiorni Maria Grazia
- Boriani Giuseppe
- Borret Mariano Ruiz
- Bosch Ralph
- Boswijk D. J.
- Bott Jochen
- Bottacchi Edo
- Brandes Axel
- Bratland Bj\uf8rn
- Brautigam Donald
- Breton Nicolas
- Briones Ignacio Rodriguez
- Brkljacic Diana Delic
- Brouwers P. J. A. M.
- Browne Kevin
- Bruguera Jordi
- Brunehaut Myriam
- Brunschwig Claude
- Bryan Yan Ping Yen
- Buathier Herv\ue9
- Buenostro Gabriel Contreras
- Buhl Aur\ue9lie
- Bullinga John
- Butcher Kenneth
- Cabrera Honorio Jose Walter
- Caccavo Alberto
- Cadinot Didier
- Cai Shanglang
- Caiedo Carolina Guevara
- Calin Podoleanu Cristian Gheorghe
- Calvi Valeria
- Camm John
- Candeias Rui
- Cao Phai G\ue9rald Phan
- Capo James
- Capucci Alessandro
- Cardoso Juliano Novaes
- Carlson Brian
- Carvalho Paula
- Cary Susanna
- Casanova Rene
- Casu Gavino
- Cattan Simon
- Cavallini Claudio
- Cayla Guillaume
- Cha Kwang Soo
- Cha Tae Joon
- Chaaban Said
- Chae Jei Keon
- Challappa Krishnan
- Chand Sunil
- Chandrashekar Harinath
- Chang Mark
- Charbel Paul
- Chartier Ludovic
- Chatterjee Kausik
- Cheema Aamir
- Chen Shih Ann
- Chevallereau Pierre
- Chiang Fu Tien
- Chiarella Francesco
- Chih Chan Lin
- Cho Yong Keun
- Choi Dong Ju
- Chouinard Guy
- Chow Hoi Fan
- Chreih Rami Mihail
- Chrysos Dimitrios
- Chumakova Galina
- Cieza Lara Tomas
- Ciobotaru Vlad
- Cislowski David
- Citerne Olivier
- Claus Matthias
- Clay Anthony
- Clifford Piers
- Cocina Emilio Gonzalez
- Cohen Andrew
- Cohen Serge
- Colivicchi Furio
- Collins R\uf3n\ue1n
- Compton Steve
- Connors Sean
- Conti Alberto
- Coodley Gregg
- Cooper Martin
- Corbett Lynn
- Corey Oran
- Coronel Juli\ue1n
- Corrigan John
- Cotrina Pereyra Rosa Ysabel
- Cottin Yves
- Coutu Benoit
- Cracan Aurel
- Crean Peter
- Crenshaw James
- Crijns H. J. G. M.
- Crump Charles
- Cucher Fred
- Cudmore David
- Cui Lianqun
- Culp John
- D'Souza Anthony
- Daniel Oh Chia Theng
- Danny Null
- Darius Harald
- Dary Patrick
- Dascotte Olivier
- Dauber Ira
- Davee Thomas
- Davies Ruth
- Davis Gershan
- Davy Jean Marc
- Dayer Mark
- De La Briolle Axel
- de Los Rios Ibarra Manuel Odin
- de Mora Manuel
- de Souza Olga Ferreira
- De Teresa Eduardo
- De Wolf Luc
- Decoulx Eric
- Deepak Sasalu
- Defaye Pascal
- Del Carpio Munoz Freddy
- Deluche Laurent
- Destrac Sylvain
- Deumite N. Joseph
- Di Legge Silvia
- Dibon Olivier
- Diemberger Igor
- Diener Hans Christoph
- Dillinger Jean
- Dion\uedsio Pedro
- Dotani Imran
- Dotcheva Elena
- Duarte Vera Yan Carlos
- Dubner Sergio J.
- Dubrey Simon
- Ducrocq Xavier
- Dupljakov Dmitry
- Duthinh Vuong
- Dutra Oscar Pereira
- Dutta Dipankar
- Duvilla Nathalie
- Dy Johnny
- Dziewas Rainer
- Eaton Charles
- Eaves William
- Ebinger Matthew
- Eck van J. W. M.
- Edwards Tim
- Egocheaga Isabel
- Ehrlich Clifford
- Eisenberg Steven
- El Hallak Abdel
- El Hamdani Mehiar
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- El Mahmoud Rami
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- Elsaesser Amelie
- Elvan A.
- Erickson Bernard
- Espaliat Eric
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- Everington Tamara
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- Ezhov Andrey
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- Fisher Raymond
- Floyd John
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- Forman Steven
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- Fruntelata Ana Gabriela
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- Greer Gerald
- Gremmler Uwe
- Grena Paul
- Grinshstein Yuriy
- Grond Martin
- Gronda Edoardo
- Grondin Francois
- Groot de J. R.
- Guardigli Gabriele
- Guarnieri Thomas
- Guignier Alexandre
- Gulizia Michele
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- Heggelund Geir
- Hemels M. E. W.
- Hemery Yann
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- Henz Benhur
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- Hernandes Mauro Esteves
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- Huisman Menno V
- Huizenga A.
- Huntley Richard
- Hussein Gamal
- Hwang Gyo Seung
- Igbokidi Oyidie
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- Ikpoh Margaret
- Imberti Davide
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- Iteld Bruce
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- Jang Sung Won
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- Jiang Heng
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- Jimenez Javier
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- Jones Nick
- Jos\ue9 Roberto Chuquiure Valenzuela Eduardo Juli\ue1n
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- Juanatey Carlos Gonzalez
- Jundi Mayar
- Jung Byung Chun
- Jung Kyung Tae
- Jung Werner
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- Keeling Phil
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- Kes Vanja Basic
- Ketova Galina
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- Kim Dae Kyeong
- Kim Doo Il
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- Kinova Elena
- Klein Alexander
- Kleinschnitz Christoph
- Kmetzo James
- Kneller G. Larsen
- Knezevic Aleksandar
- Koch Stanley
- Koenig Kai
- Koons Jay
- Korabathina Ravikiran
- Korennova Olga
- Koschutnik Martin
- Kosinski Edward
- Kovacic Dragan
- Kowalczyk Jacek
- Koziolova Natalya
- Kragten J. A.
- Krause Lars Udo
- Kreidieh Imad
- Krenning B. J.
- Krishnaswamy Kannappan
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- Kuck Karl Heinz
- Kumar Somnath
- Kuniss Malte
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- Kurrelmeyer Karla
- Kwan Tak
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- L\uf3pez Send\uf3n Jos\ue9
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- Lam Andy
- Lanas Zanetti Fernando Tomas
- Landau Charles
- Landini Giancarlo
- Lang Wilfried
- Larsen Torben Bjerregaard
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- Lee Daniel
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- Lenarczyk Radoslaw
- Leprince Patrick
- Lequeux Benoit
- Leschke Matthias
- Ley Nicolas
- Li Weihua
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- Li Zhanquan
- Li Zicheng
- Liang Jianqiu
- Lieber Ira
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- Limon Rodriguez Ramon Horacio
- Lin Hailong
- Lip Gregory
- Lip Gregory Y. H.
- Litchfield Jennifer
- Liu Feng
- Liu Wenhui
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- Liu Yalin
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- Llamas Esperon Guillermo Antonio
- Llisterri Jose Luis
- Lo Eric
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- Lodde Bernhard Paul
- Loiselet Philippe
- Lorga Filho Adalberto Menezes
- Lori Ido
- Luo Ming
- Lupovitch Steven
- Lyrer Philippe
- M\ufcgge Andreas
- Ma Chang Sheng
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- Magnin Dominique
- Mahmood Shahid
- Mahood Karen
- Maid Gustavo
- Mainigi Sumeet
- Makaritsis Konstantinos
- Maldonado Villalon Jos\ue9 Arturo
- Malhotra Rohit
- Malik Amir
- Mallecourt Catherine
- Mallik Rajiv
- Manning Rickey
- Manolis Athanasios
- Mantas Ioannis
- Manzur Jattin Fernando Gabriel
- Mar\uedn Francisco
- Marcionni Niccolo'
- Marin Javier Aguila
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- Pardell Herbert
- Park Hyung Wook
- Park Jong Sung
- Parkash Ratika
- Parker Ian
- Parrens Eric
- Parris Robert
- Pascual Carlos Rodr\uedguez
- Passamonti Enrico
- Patel Jaydutt
- Patel Rajesh
- Pentz William H.
- Pereira Jardim Cesar Augusto
- Persic Viktor
- Perticone Francesco
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- Polasek Petr
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- Porro Yamile
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- Pouzar Joe
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- Puleo John
- Pye Maurice
- Qaddoura Fatma
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- Quintana Antonio Garcia
- Raev Dimitar
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- Reyes Rocha Miguel Agustin
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- Reza Shabbir
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- Richter Dimitrios
- Rickli Hans
- Rickner Kyle
- Rieker Werner
- Rigo Fausto
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- Roelke Marc
- Roman Mark
- Romeo Francesco
- Ronner E.
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- Rooyer F. A.
- Rosenbaum David
- Roth Sherryn
- Rothman Kenneth J.
- Rozkova Nadezda
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- Rubalcava Frank
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- Rybak Karin
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- Seidman Barry
- Sek Jaroslaw
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- Sepulveda Varela Pablo Andres
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- Shah Aman
- Shah Anil
- Shah Neerav
- Shah Vinay
- Shanes Jeffrey
- Sharareh Ali
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- Shaw Louise
- Shimizu Yutaka
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- Shin Dong Gu
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- Shite Junya
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- Silver Frank
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- Simmers T. A.
- Singal Dinesh
- Singh Narendra
- Siostrzonek Peter
- Sirajuddin Mohiburrahman
- Skeppholm Mika
- Smadja Didier
- Smith David
- Smith Richard
- Soda Hassan
- Sofley C. Wilson
- Sokal Adam
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- Sparby Jon Arne
- Spinar Jindrich
- Sprigings David
- Spyropoulos Alex
- Stakos Dimitrios
- Steinberg Alon
- Steinwender Clemens
- Stergiou Georgios
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- Stoikov Anastas
- Strasser Ruth
- Streb Witold
- Styliadis Ioannis
- Su Guohai
- Su Xi
- Suarez Rafael Martin
- Sudnik Wanda
- Sueyoshi Atsushi
- Sukles Kai
- Sun Li
- Suneja Randeep
- Svensson Peter
- Szavits Nossan Janko
- Taggeselle Jens
- Takagi Yuichiro
- Takhar Amrit
- Tallet Julio
- Tamm Angelika
- Tanaka Katsumi
- Tanaka Shozo
- Tang Aylmer
- Tang Sherman
- Tassinari Tiziana
- Tayama Shinji
- Tayebjee Muzahir
- Tebbe Ulrich
- Teixeira Jose
- Tesloianu Dan Nicolae
- Tessier Pascal
- Teutsch Christine
- The S. H. K.
- Thevenin J\ue9rome
- Thomas Harold
- Timsit Serge
- Topkis Robert
- Torosoff Mikhail
- Touze Emmanuel
- Traissac Thalie
- Trendafilova Elina
- Troyan Barry
- Tsai Wenchi Kevin
- Tse Hung Fat
- Tsutsui Hiroshi
- Tsutsui Takashi
- Tuininga Y. S.
- Turakhia Minang
- Turk Samir
- Turner Wayne
- Tveit Arnljot
- Twiddy Shannon
- Tytus Richard
- Ukrainski Gerald
- Valdovinos Chavez Salvador Bruno
- Van De Graaff Eric
- Vanacker Peter
- Vardas Panagiotis
- Vargas Michael
- Vassilikos Vassilios
- Vazquez Juan
- Venkataraman Asok
- Verdecchia Paolo
- Vester Ernst G\ufcnter
- Vial Hubert
- Vicenzo de Paola Angelo Amato
- Vinereanu Dragos
- Vlastaris Anthony
- Vogel Craig
- vom Dahl J\ufcrgen
- von Mering Matthias
- Vora Kishor
- Wakefield Paul
- Walia Jasjit
- Walter Thomas
- Wang Feng
- Wang Kuo Yang
- Wang Mingsheng
- Wang Ningfu
- Wang Xinhua
- Wang Zulu
- Watanabe Kouki
- Wei Jeanne
- Weimar Christian
- Weinrich Renate
- Wen Ming Shien
- Wheelan Kevin
- Wicke Jens
- Wiemer Marcus
- Wild Beate
- Wilke Andreas
- Willems Stephan
- Williams David
- Williams Marcus
- Winkler Andreas
- Wirtz Jost Henner
- Witzenbichler Bernhard
- Wong Brian
- Wong Danny H. K.
- Wozakowska Kaplon Beata
- Wu Shulin
- Wu Zhaohui
- Wyatt Nell
- Xu Xiangdong
- Xu Yong
- Yamada Akira
- Yamamoto Kazuya
- Yamanoue Hiroki
- Yamashita Takeshi
- Yang Tianlun
- Yang Yanmin
- Yao Jing
- Yarlagadda Chakri
- Yeh Kuo Ho
- Yotov Yoto
- Yvorra Serge
- Zahn Ralf
- Zamorano Jos\ue9
- Zanini Roberto
- Zarich Stuart
- Zebrack James
- Zenin Sergei
- Zeuthen Elisabeth Louise
- Zhang Dadong
- Zhang Donghui
- Zhang Huanyi
- Zhang Quansan
- Zhang Xingwei
- Zhao Shuiping
- Zhao Xinwen
- Zheng Qiangsun
- Zheng Yang
- Zhou Jian
- Zhou Jing
- Ziekenhuis Antonius
- Zimmermann Rainer
- Zimmermann Sergio Luiz
- Zint Kristina
- Zuhairy Hamed M.
- Zukerman L. Steven
- Zwaan van der C.
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2017
- Field of study
Background GLORIA-AF (Global Registry on Long-Term Oral Antithrombotic Treatment in Patients with Atrial Fibrillation) is a prospective, global registry program describing antithrombotic treatment patterns in patients with newly diagnosed nonvalvular atrial fibrillation at risk of stroke. Phase 2 began when dabigatran, the first non\u2013vitamin K antagonist oral anticoagulant (NOAC), became available. Objectives This study sought to describe phase 2 baseline data and compare these with the pre-NOAC era collected during phase 1. Methods During phase 2, 15,641 consenting patients were enrolled (November 2011 to December 2014); 15,092 were eligible. This pre-specified cross-sectional analysis describes eligible patients\u2019 baseline characteristics. Atrial fibrillation disease characteristics, medical outcomes, and concomitant diseases and medications were collected. Data were analyzed using descriptive statistics. Results Of the total patients, 45.5% were female; median age was 71 (interquartile range: 64, 78) years. Patients were from Europe (47.1%), North America (22.5%), Asia (20.3%), Latin America (6.0%), and the Middle East/Africa (4.0%). Most had high stroke risk (CHA2DS2-VASc [Congestive heart failure, Hypertension, Age 6575 years, Diabetes mellitus, previous Stroke, Vascular disease, Age 65 to 74 years, Sex category] score 652; 86.1%); 13.9% had moderate risk (CHA2DS2-VASc = 1). Overall, 79.9% received oral anticoagulants, of whom 47.6% received NOAC and 32.3% vitamin K antagonists (VKA); 12.1% received antiplatelet agents; 7.8% received no antithrombotic treatment. For comparison, the proportion of phase 1 patients (of N = 1,063 all eligible) prescribed VKA was 32.8%, acetylsalicylic acid 41.7%, and no therapy 20.2%. In Europe in phase 2, treatment with NOAC was more common than VKA (52.3% and 37.8%, respectively); 6.0% of patients received antiplatelet treatment; and 3.8% received no antithrombotic treatment. In North America, 52.1%, 26.2%, and 14.0% of patients received NOAC, VKA, and antiplatelet drugs, respectively; 7.5% received no antithrombotic treatment. NOAC use was less common in Asia (27.7%), where 27.5% of patients received VKA, 25.0% antiplatelet drugs, and 19.8% no antithrombotic treatment. Conclusions The baseline data from GLORIA-AF phase 2 demonstrate that in newly diagnosed nonvalvular atrial fibrillation patients, NOAC have been highly adopted into practice, becoming more frequently prescribed than VKA in Europe and North America. Worldwide, however, a large proportion of patients remain undertreated, particularly in Asia and North America. (Global Registry on Long-Term Oral Antithrombotic Treatment in Patients With Atrial Fibrillation [GLORIA-AF]; NCT01468701
Finishing the euchromatic sequence of the human genome
- Author
- . Haifeng
- . Magner
- . Yin
- Abbott Scott
- Abbott-Ozersky Amanda
- Abdellah Zahra
- Abouelleil Amr
- Abrajano Anne
- Adachi Tamami
- Adam Catherine
- Adams Charles Q.
- Adamson Aaron
- Adekoya Emmanuel
- Adio-Oduola Babajide
- Aerts Andrea
- Aggarwal Arun
- Ahmadi Alireza
- Ahmed Shahana
- Aimable Matthew
- Ainscough Rachael
- Ait-Zahra Mostafa
- Aizu Tomoyuki
- Alcivare Dana
- Alegria Michelle
- Ali Alla
- Ali Johar
- Allegria-hartmann Michelle
- Alleman Jennifer
- Allen Carlana C.
- Allen Heather
- Allen Nicole R.
- Allen Susan
- Allen Thaddeus
- Almeida Jeff
- Almond Claire
- Alsbrooks Stephen L.
- Altherr Michael R.
- Amaratunge Harshinie C.
- Ambler Andrew
- Ambrose Karen
- Ambrose Kerrie
- Amemiya Chris
- Amico-Keller Gina
- Amin Amita G.
- Anderson Mechele
- Anderson Scott
- Anderson Scott
- Andora Janice
- Andredesz Carol
- Andrew Robert
- Andrews Dan
- Andrews Daniel
- Andrews Neil
- Andrews Stephanie
- Andriese Tim
- Anthouard Véronique
- Antonarakis Stylianos E.
- Anyalebechi Vivian
- Aoki Norie
- Apostolou Sinoula
- Apweiler Eva
- Arachchi Harindra
- Arai Rie
- Arbery Hazel
- Arcaina Marlon
- Arcaina Terisita
- Archer Beth
- Arellano Andre
- Arellano-Jones Perry
- Armbruster Jeff
- Armstrong Jon
- Arredondo Dilrukshi P.
- Arredondo Heather Hope
- Artiguenave François
- Asakawa Shuichi
- Asakawa Teruyo
- Ash Gareth
- Ashcroft Kevin
- Ashurst Jennifer
- Ashwell Robert
- Ashworth Linda K.
- Aslanidis Cara
- Asomugha Chinwe O.
- Asuncion Lawreen
- Atkin Deborah
- Atkinson Andrea
- Atkinson Barry
- Attix Cristina
- Attwood John
- Aubin Keith
- Auger Katherine
- Austin Shannon Michelle
- Avila Aaron
- Avis Terry
- Ayele Mulu
- Babayan Primo
- Babbage Anne
- Babbage Sarah
- Bach Phil
- Bachatsang Pasang
- Bacon Joanne
- Badri Hummy
- Baertsch Robert
- Bagguley Claire
- Bailey Jonathan
- Bajorek Eva
- Baker Andrew
- Baker Dan
- Baker M.
- Baker Richard
- Bakis Michele
- Baldwin Jennifer
- Banda Michael
- Banerjee Ruby
- Bao Jingyue
- Bao Qiyu
- Bao Weidong
- Bao Weidong
- Baptiste Pertrice
- Barbaria Joseph A.
- Barbe Valérie
- Bardill Simon
- Barker Daniel
- Barker Darren
- Barker Gary
- Barlow Karen
- Baron Laurent
- Barrett Anika
- Bartlett Rebecca
- Basham Victoria
- Bashman David
- Basu Suba
- Bateman Alex
- Bates Karen
- Battles John
- Batzer Mark
- Baumgart Cornelia
- Baumohl Jason
- Baynes Caroline
- Bayul Tashi
- Beall Keith
- Beard Lisa
- Beard Susan
- Beare David
- Beasley Alastair
- Beasley Helen
- Beasley Oliver
- Beaucham Leslie
- Beaudet Arthur
- Beck Alfred
- Beck Stephen
- Becker Michael
- Bell Emma
- Bell George I.
- Bellard Terell M.
- Bellerby Damian
- Bellerby Tristram
- Belter Edward A., Jr.
- Bemrose Richard
- Benard Michael Anthony
- BenKahla Alia
- Benke J
- Benner William
- Bennett James
- Bensasson Douda
- Bentley Andrew
- Bentley Dan
- Bentley David
- Berardinis Véronique de
- Bercovitz John
- Berghoff Amy
- Bergmann Anne
- Berkowicz Nicolas
- Berks Mary
- Berks Michael
- Bethel Graeme
- Beugelsdijk Tony J.
- Bhakta Rita
- Bhuchar Venita
- Bi Shihua
- Bian Xuemeng
- Bieri Tamberlyn
- Bimage Kesha E.
- Bird Christine
- Birditt Brian
- Birney Ewan
- Birney Ewan
- Birren Bruce
- Bissell Helen
- Biswalo Kaneza
- Bituin Aleksandr
- Black Stacey
- Blackburne-Maze Suzanne
- Blair Jessica Anne
- Blakey Sarah
- Blanks Tia
- Blasiar Darin
- Blazej Robert
- Blitshsteyn Berta
- Blomstrom David B.
- Bloom Scott
- Bloom Toby
- Blumer Heather
- Blye Jason
- Blyth Peter R.
- Blöcker Helmut
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- Brandriff Brigitte F.
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- Brettin Thomas
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- Brimhall Angela K.
- Brokstein Peter
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- Curran Adam
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- Daum Christopher
- David Robert
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- Dawson Elisabeth
- De Anda Claudia
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- Degusta David
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- Evans Gareth
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- Footman Simon
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- Fujiyama Asao
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- Furey Terrence S.
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- Förste Silke
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- Geng Jianing
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- Griffiths Coline
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- Hammond Sian
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- Han Guiqing
- Han Shunsheng
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- Hancock Julie
- Harbes Brandy A.
- Harding Adam
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- Hawkins Natalie
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- Heyen Joshua
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- Hines Sandra
- Hinkins Russell
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- Hitchens Matthew Edward
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- Hodgson David
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- Hynds Christopher
- Idlebird Devincent G.
- Iliev Ilian
- Imbro Paula
- Imo Kelvin C.
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- Ishibashi Akiko
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- Ishizaki Hinako
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- Iwakawa Shinobu
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- Jeffery Grant
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- Jia Jia
- Jia Jia
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- Kettleborough Ross
- Keys David
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- Khan Umer F.
- Khan Ziad Mohid
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- Kong Yi
- Korf Ian
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- Kou Zhaohui
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- Krawczyk Marie-Claude
- Kremitzki Colin
- Kremmidiotis Gabriel
- Krogh Anders
- Kronmiller Brent
- Kruchowski Scott S.
- Kube Michael
- Kubischta Duane
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- Lander Eric S.
- Landers Tom
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- Lei Meng
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- Levan Jaclyn M.
- Leversha Margaret
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- Lewis Tammy
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- Lim Meng K.
- Lindblad-Toh Kerstin
- Lindo Ken
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- Liu Yu
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- Longmire Johnathan L.
- Lopez Frederick
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- Lou Yunian
- Loulseged Hermela
- Loveland Jane
- Lovell Jamie
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- Lowry Stephen
- Lozado Ryan J.
- Lu Lingfeng
- Lu Tao
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- Lu Yue
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- Lucas Susan
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- Lucier Raymond L.
- Ludeman Thom
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- Ma Xiaohui
- Maas Jason
- Mabbitt Richard
- Macdonald Pendexter
- Machrus Migdad
- Macht Madison
- Macken Catherine A.
- MacLean Christine
- Madabhushi Ramki
- Madu Renita C.
- Maeda Hideto
- Maglott Donna
- Maheshwari Manjula
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- Mahmoodi Venus
- Mahnke Ryan
- Mailey Brian
- Major John
- Malfatti Stephanie
- Malloy Kevin
- Maltbie Mary I.
- Mangum Brian
- Manning Jonathan
- Manohar Chitra
- Mapua Patricia
- Marabella Dick
- Mardis Elaine R.
- Mareth David
- Mariano Marisa
- Marinelli Lisa
- Mark Graham A.
- Marquis-Homeyer Catherine
- Marr Thomas G.
- Marra Marco
- Marriott Neil
- Marrone Anne
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- Marsh Victoria
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- Maslen Gareth
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- Matsushita Yoshitaka
- Matthews Charles D.
- Matthews Lucy
- Matthews Nick
- Matthews Paul
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- Mauceli Evan
- Maunes Cynthia
- Maupin Rachel
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- McLay Kirsten
- McLean James
- McLellan Michael D.
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- McMurdo John
- McMurray Amanda
- McMurray Des
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- Mejima Mio
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- Mu Feng
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- Mulrain Leon
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- Mundt Mark O.
- Mungall Andy
- Munidasa Mala
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- Murayama Yuji
- Murnane Clare
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- Murphy Michael
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- Nwokenkwo Stanley
- O\u27Donnell Paula
- O\u27Donovan Daniel
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- O\u27Loughlin Jennifer
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- Olson Maynard V.
- Omotosho Bamidele
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- Oragunye Njideka
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- Oviedo Rodolfo J.
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- Sarmiento R.
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- Tam Serena
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- Tamirisa Aparna
- Tan Olivia
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- Thomas Daryl J.
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- Thomas Ruth
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- Warren Graham
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- Warry Georgina
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- Weber Ryan J.
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- Yada Tetsushi
- Yadav Shailendra
- Yakub Syed
- Yamamoto Lynn
- Yamamoto Noriko
- Yamamoto Yuko
- Yamashita Yasue
- Yamazaki Satoru
- Yang Hao
- Yang Huanming
- Yang Huanming
- Yang Joan
- Yang Shiaw-Pyng
- Yang Shudong
- Yang Xiaonan
- Yang Xiaonan
- Yang Xiaoping
- Yang Yongkui
- Yano Candance
- Yao Zhijian
- Yao Zhijian
- Yaspo Marie-Laure
- Ye Chen
- Yeager Shane
- Yeh Mimi
- Yen Jennifer
- Yeshitela Rahel Retta
- Yoakum Martin
- Yokobata Kathy
- Yokoyama Jennifer
- Yonezawa Miho
- Yoon Lillienne
- Yoon Vivienne
- Yoshida Satoru
- You Bo
- Young Geneva
- Young Louise
- Young Shelia
- Younger Ruth
- Yu Bing
- Yu Charles
- Yu Fuli
- Yu Jun
- Yu Jun
- Yu Jun
- Yuan Kaiwen
- Yuan Ye
- Yuan Yida
- Yue Shujie
- Yumae Brian
- Yun Rui
- Zainoun Joanne
- Zembeck Lisa
- Zeng Yixin
- Zhai Dong
- Zhan Guoping
- Zhang Bo
- Zhang Caimin
- Zhang Fengmei
- Zhang Guangyu
- Zhang Guohua
- Zhang Guohua
- Zhang Haiqing
- Zhang Haiqing
- Zhang Haiqing
- Zhang Hongbo
- Zhang Hongbo
- Zhang Jingjing
- Zhang Jingjing
- Zhang Jingkun
- Zhang Jiuchun
- Zhang Jiuchun
- Zhang Lanzhi
- Zhang Li
- Zhang Li
- Zhang Meihua
- Zhang Meng
- Zhang Ming
- Zhang Qing
- Zhang Ruhua
- Zhang Shaojie
- Zhang Tiezhen
- Zhang Wei
- Zhang Wei
- Zhang Xianglin
- Zhang Xianglin
- Zhang Xiaoliang
- Zhang Xiuqing
- Zhang Yan
- Zhang Yi
- Zhang Yilin
- Zhang Yilin
- Zhang Ying
- Zhang Yuansen
- Zhang Yuzhi
- Zhang Zhengdong
- Zhao Hongmei
- Zhao Lijian
- Zhao Shenru
- Zhao Zhijing
- Zhen Zhicheng
- Zheng Haibo
- Zhong Ming
- Zhou Carol
- Zhou Haixia
- Zhou Jianling
- Zhou Nannan
- Zhou Xinfeng
- Zhou Yan
- Zhou Yang
- Zhou Yi
- Zhu Bingying
- Zhu Bofeng
- Zhu Fenghua
- Zhu Genfeng
- Zhu Genfeng
- Zhu Miao
- Zhu Ning
- Zhu Yongge
- Zhu Zhen
- Zhuang Shitao
- Zierten Deborah
- Zimmer Andrew
- Zody Michael C.
- Zollo Massimo
- Zorrilla Sara E.
- Zuo Lin
- Publication venue
- LSU Digital Commons
- Publication date
- 21/10/2004
- Field of study
The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead
Safety and tolerability of an anti-CD19 monoclonal antibody, MEDI-551, in subjects with systemic sclerosis: a phase I, randomized, placebo-controlled, escalating single-dose study
- Author
- A Francois
- A Lanteri
- AC Desbois
- Armando Flor
- BA Baldo
- Barbara White
- CH Chung
- CP Denton
- D Daoussis
- D Daoussis
- D Daoussis
- D Khanna
- Daniel Cimbora
- DB Clifford
- DJ DiLillo
- E Ward
- Elena Schiopu
- Eliezer Katz
- F Hoogen van den
- H Huang
- HE Harris
- Jing Li
- JL Hankinson
- JL Hankinson
- Jorn Drappa
- JP Zuber
- K Dunleavy
- K Owczarczyk
- K Streicher
- Kathleen McKeever
- Katie Streicher
- Kaushik Patra
- LI Sakkas
- M Hasegawa
- M Hasegawa
- M Mahevas
- MC Dalakas
- MD Mayes
- ML Whitfield
- MR Miller
- O Kowal-Bielecka
- P Clements
- P Engel
- PJ Brennan
- PJ Clements
- PP Sfikakis
- R Eisenberg
- R Fleischmajer
- R Herbst
- R Lafyatis
- R Rios-Fernandez
- R Sabahi
- RF Vollenhoven van
- RJ Keizer
- RM Bertina
- Ronald Herbst
- S Bosello
- S Bosello
- S Cappelli
- S Jordan
- S Sato
- S Sato
- S Sato
- Sarah Sweeny
- Soumya Chatterjee
- T Matsushita
- TF Tedder
- V Smith
- Vivien Hsu
- Wenliang Yao
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking
- Author
- Agarwal Vinayak
- Aigle Bertrand
- Alexandrov Theodore
- Allard Pierre-Marie
- Almaliti Jehad
- Bandeira Nuno
- Baric Ralph
- Boudreau Paul D.
- Bouslimani Amina
- Boya Cristopher A.P.
- Briand Enora
- Carlson Erin E.
- Carver Jeremy J.
- Charusanti Pep
- Crüsemann Max
- Dai Jingqui
- Demarque Daniel P.
- Dorrestein Kathleen
- Dorrestein Pieter C.
- Duggan Brendan M.
- Duncan Katherine R.
- Dutton Rachel J.
- Edlund Anna
- Elfeki Maryam
- Engene Niclas
- Esquenazi Eduardo
- Floros Dimitrios J.
- Garg Neha
- Gavilan Ronnie G.
- Gerwick Lena
- Gerwick William H.
- Glukhov Evgenia
- Gonzalez David J.
- Granatosky Eve A.
- Gurr Joshua
- Gutiérrez Marcelino
- Helfrich Eric J. N.
- Hoffman Thomas
- Houson Hailey
- Hsu Cheng-Chih
- Humpf Hans-Ulrich
- Jadhav Ajit
- Jelsbak Lars
- Jenkins Stefan
- Jensen Paul R.
- Johnson Andrew R.
- Kapono Clifford A.
- Kersten Roland D.
- Keyzers Robert A.
- Kharbush Jenan J.
- Kleigrewe Karin
- Klitgaard Andreas
- Knight Rob
- Koyama Nobuhiro
- Kurita Kenji L.
- Kyle Jennifer E.
- Lamsa Anne
- Larson Charles B.
- Liaw Chih-Chuang
- Linington Roger G.
- Litaudon Marc
- Liu Wei-Ting
- Liu Xueting
- Lopes Norberto P.
- Luzzatto-Knaan Tal
- Maansson Maria
- Macherla Venkat
- Marques Lucas M.
- Mascuch Samantha J.
- McLean Jeffrey
- McPhail Kerry L.
- Meehan Michael J.
- Melnik Alexey V.
- Metz Thomas O.
- Michelsen Charlotte F.
- Mohimani Hosein
- Moore Bradley S.
- Murphy Brian T.
- Müller Rolf
- Neupane Ram
- Nguyen Dac-Trung
- Nguyen Don Duy
- Nielsen Kristian Fog
- Northen Trent
- Nothias Louis-Felix
- O'Neill Ellis C.
- Pace Laura A.
- Palsson Bernhard Ø
- Parrot Delphine
- Peng Yao
- Peryea Tyler
- Pevzner Pavel
- Phapale Prasad
- Phelan Vanessa V.
- Piel Jörn
- Pociute Egle
- Pogliano Kit
- Porto Carla
- Quinn Robert A.
- Rodríguez Andrés M. C.
- Ryffel Florian
- Sanchez Laura M.
- Sandoval-Calderón Mario
- Sedio Brian E.
- Shi Wenyuan
- Shinn Paul
- Sidebottom Ashley M.
- Silva Denise B.
- Silva Ricardo R.
- Sims Amy C.
- Sohlenkamp Christian
- Tomasi Sophie
- Torres-Mendoza Daniel
- Traxler Matthew F.
- VanLeer Danielle
- Vining Oliver B.
- Vorholt Julia A.
- Vuong Lisa
- Wang Mingxun
- Waters Katrina M.
- Watrous Jeramie
- Williams Philip G.
- Wolfender Jean-Luc
- Yang Yu-Liang
- Zeng Yi
- Zhang Chen
- Zhang Lixin
- Publication venue
- Publication date
- 01/01/2016
- Field of study
The potential of the diverse chemistries present in natural products (NP) for biotechnology and medicine remains untapped because NP databases are not searchable with raw data and the NP community has no way to share data other than in published papers. Although mass spectrometry techniques are well-suited to high-throughput characterization of natural products, there is a pressing need for an infrastructure to enable sharing and curation of data. We present Global Natural Products Social molecular networking (GNPS, http://gnps.ucsd.edu), an open-access knowledge base for community wide organization and sharing of raw, processed or identified tandem mass (MS/MS) spectrometry data. In GNPS crowdsourced curation of freely available community-wide reference MS libraries will underpin improved annotations. Data-driven social-networking should facilitate identification of spectra and foster collaborations. We also introduce the concept of ‘living data’ through continuous reanalysis of deposited data
Patient and stakeholder engagement learnings: PREP-IT as a case study
- Author
- Acerboni-Flores Francesc
- Achor Timothy
- Adams John D.
- Ahn Jaimo
- Ahn James S.
- Alavedra-Massana Anna
- Allen Elizabeth M.
- Altman Kyle M.
- Anglada-Torres Neus
- Apostle Kelly L.
- Babcock Sharon
- Baele Joseph R.
- Bailey Daniel
- Bansal Mira
- Bartel Claire
- Beckish Michael
- Bedard Julia C.
- Beer Robert
- Belaye Tigist
- Berenguer Alexandre
- Bergin Patrick F.
- Berhaneselase Eleni
- Bhanat Eldrin L.
- Bhandari Mohit
- Blasman Jenna
- Bosse Michael
- Boulton Christina
- Boyce Robert
- Boyer Dory S.
- Bray Christopher
- Breslin Mary A.
- Brown Timothy R.
- Brownrigg Maggie
- Bueno-Ruiz Mercedes
- Bullard Debra
- Burnikel Alex
- Camara Megan
- Caparros-García Ariadna
- Carballo Alejandro
- Carlisle II Robert M.
- Carroll Eben A.
- Champion Heather K.
- Choo Andrew M.
- Churchill Christine
- Clark Linda
- Coe Marcus
- Cole Austin A.
- Colello Michael
- Cross Andrew W.
- Crus Alejandro
- Cuff Jaslynn A.N.
- Culbert Hunter
- Cámara-Cabrera Jaume
- D'alleyrand Jean-Claude
- Das Sharmistha
- Davies Jonah
- Degani Yasmin
- Dehghan Niloofar
- Del Fabbro Gina
- Della Rocca Gregory J.
- Demyanovich Haley
- DePalo Peter
- Devereaux Pj
- Dew Timothy
- Ding Anthony
- Dodds Shannon
- Donegan Derek
- Donohue Erin
- Dooley Mary
- Dwyer Kevin
- Dykes Tayler
- Eglseder Andrew
- English Antoinisha D.
- Esposito John
- Fan Chen "Brenda"
- Faucher Gregory
- Fillat-Gomà Ferran
- Fowler Justin
- Fowler Justin
- Fraifogl Joanne
- Friedrich Jeff
- Fuentes-López Ruben
- Gage Mark J.
- Gajari Vamshi
- Garcia-Rodriguez Ramona
- García Yaiza
- Gardner Michael J.
- Garg Kartik
- Garibaldi Alisha
- Garitty Michael J.
- Gary Joshua L.
- Gaski Greg E.
- Gimeno-Clavia Nuria
- Girardi Cara
- Gitajn Leah
- Goodman J. Brett
- Graells-Alonso Guillem
- Graves Matthew L.
- Grissom Frances
- Guerra-Farfán Ernesto
- Gurich Jr Richard W.
- Guyatt Gordon H.
- Haaser Sharon M.
- Hagen Jennifer E.
- Hale Diamond
- Hall Amy E.
- Haller Justin M.
- Halliday Paul G.
- Halvorson Jason J.
- Harris Anthony
- Harris Mitchel B.
- Hebden Joan
- Heels-Ansdell Dianne
- Heng Marilyn
- Higgins Thomas F.
- Hill Lauren C.
- Hofer Erin Adams
- Holden Martha B.
- Hollinsworth Troy
- Holzman Michael A.
- Horan Annamarie
- Horne Brandon
- Howe Andrea
- Hsu Joseph
- Hudgins Andrea
- Huggins Brandon S.
- Hunter Michael D.
- Hurkett Colin
- Hymes Robert A.
- Iwu Ashley
- Jaeblon Todd
- Jahangir Amir Alex
- Jeray Kyle J.
- Jerele Jennifer
- Johnson Aaron
- Johnson Leslie N.
- Jones Clifford B.
- Jornet-Gibert Montsant
- Joseph Katherine
- Joshi Manjari G.
- Kandemir Utku
- Karim Ammar
- Karunakar Madhav
- Kempton Laurence
- Kettering Eric
- Kimmel Joseph
- Knapp Thomas
- Koenig Chris
- Krupko Thomas
- Kuczinski Ashley
- Langhammer Christopher
- Lazarus David E.
- Lebrun Christopher
- Lemke H. Michael
- Lhowe David W.
- Li Silvia
- Liang Stephen
- Little Kelly
- Loeffler Markus F.
- Love T Rosie
- Lowe Jason
- Lowney Maya
- Mahal Nirmen
- Malekzadeh A. Stephen
- Maltz Ethan J.
- Manson Theodore
- Marcano-Fernández Francesc
- Marchand Lucas
- Marmor Meir
- Marshall William A.
- Martin Abigail
- Martinez Eric
- Martí-Garín David
- Martínez-Carreres Laia
- Martínez-Grau Patricia
- Martínez-álvarez Marta
- Marvel Debra
- Matityahu Amir
- Mayberry Robert Miles
- Mayfield Ada
- McClellan R. Trigg
- McGee Skeketha L.
- McKay Paula
- McKee Michael
- McKinley Todd O.
- McTague Michael F.
- Medeiros Michelle
- Medeiros Michellic
- Mehta Samir
- Meinberg Eric
- Miclau Theodore
- Miller Adam
- Millon S. John
- Mitchell Phillip
- Moody M. Christian
- Moola Farhad O.
- Morellato John
- Morshed Saam
- Mossuto Franca
- Mullin Devin S.
- Mullins C. Daniel
- Mullins Daniel C.
- Mullis Brian H.
- Munz John W.
- Nascone Jason
- Natoli Roman M.
- Neese Ashley
- Nguyen Uyen
- O'Hara Lyndsay M.
- O'Hara Nathan
- O'Hara Nathan N.
- O'Toole Robert
- Obremskey William T.
- Osborn Patrick
- Palmer Jana
- Palmer M. Jason
- Paniagua Ariana
- Panjshiri Farhanaz
- Parker Wesley
- Paryavi Ebrahim
- Patrick Matthew
- Paul Alexandra
- Payne Kyrsten
- Pechero Guillermo
- Pelfort Xavier
- Pellejero-García Raúl
- Pensy Raymond
- Perey Bertrand H.
- Perfetto Eleanor M.
- Petrisor Bradley A.
- Peñalver Juan Manuel
- Pfaff Branden
- Pham Kayla H.
- Phelps Kevin
- Pichiotino Erin R.
- Pierrie Sarah
- Pilson Holly
- Pogorzelski David
- Polk Genevieve
- Pollack Andrew
- Poole Andrew S.
- Porter Scott E.
- Potter David
- Prayson Michael
- Pritchett Chris
- Ramsey Lolita
- Ramsey T. Bennett
- Rao Mayank
- Ray Shea Bielby
- Reilly Rachel M.
- Reily Clifford A
- Rivera Jessica
- Robertson Emily
- Rodriguez Andres
- Rodriguez Elsa
- Rojas Alejandra
- Romeo Nicholas M.
- Rothberg David L.
- Routt Milton L. "Chip"
- Rudisill Jr L. Edwin
- Rudnicki Joshua
- Russell George V.
- Russell Mark
- Ruth John T.
- Ràfols-Perramon Ona
- Sadasivan Kalia
- Saeed Sabina
- Salomò Domènech Mònica
- Sanders John L.
- Sanz-Molero Matsuyama
- Schaller Thomas M.
- Schulman Jeff E.
- Schwartz Justin
- Schwartzbach Cary C.
- Sciadini Marcus
- Scott Taryn
- Seach Andrea
- Serrano-Sanz Jorge
- Sethi Manish
- Seymour Rachel
- Shearer David
- Sietsema Debra L.
- Sims Michael L.
- Sims Stephen
- Slobogean Gerard P.
- Slobogean Gerard P.
- Smith Cory D.
- Smith R. Malcolm
- Snider Rebecca G.
- Soler-Cano Albert
- Sorkin Anthony T.
- Sparrow Cindy
- Spicer Ella
- Sprague Sheila
- Sprague Sheila
- Sridhar Michael S.
- Stewart Russell
- Stinner Daniel J.
- Stone Trevor B.
- Szasz Olivia Page
- Szatkowski Jan P.
- Sánchez-Fernández Joel
- Sánchez-Palomino Estrella
- Talbot Max
- Talerico Michael
- Taljaard Monica
- Tanner Stephanie L.
- Taylor Michel
- Thabane Lehana
- Toogood Paul
- Townsend Christine E.
- Trochez Karen
- Vallier Heather A.
- Van Chi
- VanDemark II Robert
- Velasco-Barrera Aldo
- Venkatarayappa Indresh
- Virkus Walter W.
- Viskontas Darius G.
- Vlasak Richard
- von Keudel Arvind G.
- Wadenpfuhl Leanne K
- Walker Clark M.
- Warner Stephen J.
- Watson J. Tracy
- Weaver Michael J.
- Wells Jeffrey
- Wentworth Daniel
- Wild Jason
- William Alyse
- Williams Wendy
- Wilson Eleanor S.
- Wise Jeremy
- Wood Amber
- Yela-Verdú Christian
- Zomar Mauri
- Zura Robert
- Publication venue
- 'Future Medicine Ltd'
- Publication date
- 01/04/2021
- Field of study
- …