All Means All … Maybe: MTSS Policy and Practice Across States in the United States

Across the United States, State Education Agencies (SEAs) are using tiered strategies, such as Multi-Tiered System of Supports (MTSS) frameworks, to ensure that all students, including diverse learners, receive equal, high-quality education. However, little is known about the extent to which SEAs are encouraging use of MTSS to address the needs of students with moderate-to-severe cognitive disabilities. The present study aimed to examine how SEAs conceptualize and support the implementation of MTSS as an approach to inclusionary education. Data were collected through interviews with key informants in SEAs across 19 states. Members of the research team identified and coded portions of interview transcripts that related to legal requirements for MTSS at the state level, local control as an enabler of or impediment to states’ MTSS work, and levels of inclusiveness in MTSS provisions. Three criteria emerged as important to MTSS inclusiveness: (1) inclusiveness in the espoused MTSS scope; (2) extensiveness of inclusive MTSS practices; and (3) specific application of MTSS to students with significant cognitive disabilities. Analyses showed variability across states regarding their commitment to an MTSS approach across the three domains of inclusiveness. Findings showed the value of developing and disseminating MTSS models offering tiered support for all students and the need for SEA offices to engage in collaborative efforts to support the implementation of inclusive MTSS models. The study also raised questions about the role of rhetoric (i.e., All means all ) in promoting or hindering increased inclusiveness in MTSS implementation

Public access to the countryside: An exploration of the costs and benefits of farmland walking trails

To date, estimates of individuals’ willingness to pay (WTP) for access to the countryside have typically been on sites of special interest such as developed walking routes, public rights of way in specific areas, national parks and forests (see Lockwood and Tracy, 1995; Bennett and Tranter, 1997; Crabtree and MacDonald, 1997; Liston-Heyes and Heyes, 1999; Garrod et al., 1998; Bennett et al., 2003; Buckley et al., 2009; Morris et al., 2009). There has been little if any attempt to derive estimates of individuals’ WTP for the provision of walking trails in the wider countryside at a national level. The present study aims to build on previous work by examining the demand for particular types of walking trails through a nationally representative survey of the Irish population. One further advantage of this research is that apart from valuing walking activities in a generic sense this paper investigates what types of investment in facilities associated with walking trails generate the greatest welfare gains. Furthermore, using a nationally representative survey of the farming population this paper examines farmers’ willingness to participate in a hypothetical walking scheme whereby the general public will be allowed access to specific trails. First by way of background this paper will discuss the situation in relation to access rights to the countryside across a number of countries. Second this paper will outline the research approach which is followed with a discussion of the empirical results. Finally this paper will conclude with a discussion of the papers main findings and their implications for the provision of public access to the countryside.This work was funded by the Department of Agriculture, Fisheries and Food under the Stimulus Funding

The use of non-intrusive user logging to capture engineering rationale, knowledge and intent during the product life cycle

Within the context of Life Cycle Engineering it is important that structured engineering information and knowledge are captured at all phases of the product life cycle for future reference. This is especially the case for long life cycle projects which see a large number of engineering decisions made at the early to mid-stages of a product's life cycle that are needed to inform engineering decisions later on in the process. A key aspect of technology management will be the capturing of knowledge through out the product life cycle. Numerous attempts have been made to apply knowledge capture techniques to formalise engineering decision rationale and processes; however, these tend to be associated with substantial overheads on the engineer and the company through cognitive process interruptions and additional costs/time. Indeed, when life cycle deadlines come closer these capturing techniques are abandoned due the need to produce a final solution. This paper describes work carried out for non-intrusively capturing and formalising product life cycle knowledge by demonstrating the automated capture of engineering processes/rationale using user logging via an immersive virtual reality system for cable harness design and assembly planning. Associated post-experimental analyses are described which demonstrate the formalisation of structured design processes and decision representations in the form of IDEF diagrams and structured engineering change information. Potential future research directions involving more thorough logging of users are also outlined

Medicare Reimbursement for Total Joint Arthroplasty: The Driving Forces.

BACKGROUND: Total joint arthroplasty is a large and growing part of the U.S. Medicare budget, drawing attention to how much providers are paid for their services. The purpose of this study was to examine the variables that affect total joint arthroplasty reimbursement. Along with standard economic variables, we include unique health-care variables. Given the focus on value in the Affordable Care Act, the model examines the relationship of the quality of care to total joint arthroplasty reimbursement. We hoped to find that reimbursement patterns reward quality and reflect standard economic principles. METHODS: Multivariable regression was performed to identify variables that correlate with Medicare reimbursement for total joint arthroplasty. Inpatient charge or reimbursement data on Medicare reimbursements were available for 2,750 hospitals with at least 10 discharges for uncomplicated total joint arthroplasty from the Centers for Medicare & Medicaid Services (CMS) for fiscal year 2011. Reimbursement variability was examined by using the Dartmouth Atlas to group institutions into hospital referral regions and hospital service areas. Independent variables were taken from the Dartmouth Atlas, CMS, the WWAMI (Washington, Wyoming, Alaska, Montana, Idaho) Rural Health Research Center, and the United States Census. RESULTS: There were 427,207 total joint arthroplasties identified, with a weighted mean reimbursement of $14,324.84 (range,$9,103 to $38,686). Nationally, the coefficient of variation for reimbursements was 0.19. The regression model accounted for 52.5% of reimbursement variation among providers. The total joint arthroplasty provider volume (p \u3c 0.001) and patient satisfaction (p \u3c 0.001) were negatively correlated with reimbursement. Government ownership of a hospital (p \u3c 0.001) and higher Medicare costs (p \u3c 0.001) correlated positively with reimbursement. CONCLUSIONS: Medicare reimbursements for total joint arthroplasty are highly variable. Greater reimbursement was associated with lower patient volume, lower patient satisfaction, a healthier patient population, and government ownership of a hospital. As value-based reimbursement provisions of the Affordable Care Act are implemented, there will be dramatic changes in total joint arthroplasty reimbursements. To meet these changes, providers should expect qualities such as high patient volume, willingness to care for sicker patient populations, patient satisfaction, safe outcomes, and procedural demand to correlate with their reimbursement. CLINICAL RELEVANCE: Practicing orthopaedic surgeons and hospital administrators should be aware of discrepancies in inpatient reimbursement for total joint arthroplasty from Medicare. Furthermore, these discrepancies are not associated with typical economic factors. These findings warrant further investigation and collaboration between policymakers and providers to develop value-based reimbursement

Automated knowledge capture in 2D and 3D design environments

In Life Cycle Engineering, it is vital that the engineering knowledge for the product is captured throughout its life cycle in a formal and structured manner. This will allow the information to be referred to in the future by engineers who did not work on the original design but are wanting to understand the reasons that certain design decisions were made. In the past, attempts were made to try to capture this knowledge by having the engineer record the knowledge manually during a design session. However, this is not only time-consuming but is also disruptive to the creative process. Therefore, the research presented in this paper is concerned with capturing design knowledge automatically using a traditional 2D design environment and also an immersive 3D design environment. The design knowledge is captured by continuously and non-intrusively logging the user during a design session and then storing this output in a structured eXtensible Markup Language (XML) format. Next, the XML data is analysed and the design processes that are involved can be visualised by the automatic generation of IDEF0 diagrams. Using this captured knowledge, it forms the basis of an interactive online assistance system to aid future users who are carrying out a similar design task

Components of the ubiquitin-proteasome pathway compete for surfaces on Rad23 family proteins

Background: The delivery of ubiquitinated proteins to the proteasome for degradation is a key step in the regulation of the ubiquitin-proteasome pathway, yet the mechanisms underlying this step are not understood in detail. The Rad23 family of proteins is known to bind ubiquitinated proteins through its two ubiquitin-associated (UBA) domains, and may participate in the delivery of ubiquitinated proteins to the proteasome through docking via the Rad23 ubiquitin-like (UBL) domain. Results: In this study, we investigate how the interaction between the UBL and UBA domains may modulate ubiquitin recognition and the delivery of ubiquitinated proteins to the proteasome by autoinhibition. We have explored a competitive binding model using specific mutations in the UBL domain. Disrupting the intramolecular UBL-UBA domain interactions in HHR23A indeed potentiates ubiquitin-binding. Additionally, the analogous surface on the Rad23 UBL domain overlaps with that required for interaction with both proteasomes and the ubiquitin ligase Ufd2. We have found that mutation of residues on this surface affects the ability of Rad23 to deliver ubiquitinated proteins to the proteasome. Conclusions: We conclude that the competition of ubiquitin-proteasome pathway components for surfaces on Rad23 is important for the role of the Rad23 family proteins in proteasomal targeting

Darwin Tames an Andromeda Dwarf: Unraveling the Orbit of NGC 205 Using a Genetic Algorithm

NGC 205, a close satellite of the M31 galaxy, is our nearest example of a dwarf elliptical galaxy. Photometric and kinematic observations suggest that NGC 205 is undergoing tidal distortion from its interaction with M31. Despite earlier attempts, the orbit and progenitor properties of NGC 205 are not well known. We perform an optimized search for these unknowns by combining a genetic algorithm with restricted N-body simulations of the interaction. This approach, coupled with photometric and kinematic observations as constraints, allows for an effective exploration of the parameter space. We represent NGC 205 as a static Hernquist potential with embedded massless test particles that serve as tracers of surface brightness. We explore 3 distinct, initially stable configurations of test particles: cold rotating disk, warm rotating disk, and hot, pressure-supported spheroid. Each model reproduces some, but not all, of the observed features of NGC 205, leading us to speculate that a rotating progenitor with substantial pressure support could match all of the observables. Furthermore, plausible combinations of mass and scale length for the pressure-supported spheroid progenitor model reproduce the observed velocity dispersion profile. For all 3 models, orbits that best match the observables place the satellite 11+/-9 kpc behind M31 moving at very large velocities: 300-500 km/s on primarily radial orbits. Given that the observed radial component is only 54 km/s, this implies a large tangential motion for NGC 205, moving from the NW to the SE. These results suggest NGC 205 is not associated with the stellar arc observed to the NE of NGC 205. Furthermore, NGC 205's velocity appears to be near or greater than its escape velocity, signifying that the satellite is likely on its first M31 passage.Comment: 34 pages, 20 figures, accepted for publication in the Astrophysical Journal, A pdf version with high-resolution figures may be obtained from http://www.ucolick.org/~kirsten/ms.pd

Water quality in Princess Charlotte Bay flood plumes and eastern Cape York Peninsula flood plume exposure: 2012-2014

The Marine Monitoring Program (MMP) undertaken in the Great Barrier Reef lagoon assesses the long-term effectiveness of the Australian and Queensland Government’s Reef Water Quality Protection Plan and the Australian Government Reef Rescue initiative. The MMP was established in 2005 to help assess the long-term status and health of Reef ecosystems and is a critical component in the assessment of regional water quality as land management practices are improved across Reef catchments. The program forms an integral part of the Reef Plan Paddock to Reef Integrated Monitoring, Modelling and Reporting Program supported through Reef Plan and Reef Rescue initiatives. This report details the sampling that has taken place under the Marine Monitoring Program in Cape Yor

A non-apoptotic role for caspase-9 in muscle differentiation

Caspases, a family of cysteine proteases most often investigated for their roles in apoptosis, have also been demonstrated to have functions that are vital for the efficient execution of cell differentiation. One such role that has been described is the requirement of caspase-3 for the differentiation of skeletal myoblasts into myotubes but, as yet, the mechanism leading to caspase-3 activation in this case remains elusive. Here, we demonstrate that caspase-9, an initiator caspase in the mitochondrial death pathway, is responsible for the activation of caspase-3 in differentiating C2C12 cells. Reduction of caspase-9 levels, using an shRNA construct, prevented caspase-3 activation and inhibited myoblast fusion. Myosin-heavy-chain expression, which accompanies myoblastic differentiation, was not caspase-dependent. Overexpression of Bcl-xL, a protein that inhibits caspase-9 activation, had the same effect on muscle differentiation as knockdown of caspase-9. These data suggest that the mitochondrial pathway is required for differentiation; however, the release of cytochrome c or Smac (Diablo) could not be detected, raising the possibility of a novel mechanism of caspase-9 activation during muscle differentiation.</jats:p