Systematic elucidation of independently modulated genes in Lactiplantibacillus plantarum reveals a trade-off between secondary and primary metabolism

Lactiplantibacillus plantarum is a probiotic bacterium widely used in food and health industries, but its gene regulatory information is limited in existing databases, which impedes the research of its physiology and its applications. To obtain a better understanding of the transcriptional regulatory network of L. plantarum, independent component analysis of its transcriptomes was used to derive 45 sets of independently modulated genes (iModulons). Those iModulons were annotated for associated transcription factors and functional pathways, and active iModulons in response to different growth conditions were identified and characterized in detail. Eventually, the analysis of iModulon activities reveals a trade-off between regulatory activities of secondary and primary metabolism in L. plantarum

Bis[(1-methyl-1H-benzimidazol-2-yl)methanol-κ2 N 3,O]bis­(thio­cyanato-κN)cobalt(II) methanol solvate

In the mononuclear title complex, [Co(NCS)2(C9H10N2O)2]·CH3OH, the cobalt(II) ion is surrounded by two (1-methyl-1H-benzimidazol-2-yl)methanol bidentate ligands and two thio­cyanate ligands, and exhibits a distorted octa­hedral coordination by four N atoms and two O atoms. The structure is consolidated by hydrogen bonds between the organic ligand, thio­cyanate anion and the uncoordinated methanol mol­ecule, leading to a chain along [100]

Diazido­bis[(1-methyl-1H-benzimidazol-2-yl)methanol-κ2 N 3,O]manganese(II)

The title complex, [Mn(N3)2(C9H10N2O)2], possesses crystallographically imposed twofold symmetry. The MnII atom is coordinated by four N atoms and two O atoms in a distorted octa­hedral geometry. The crystal packing is stabilized by strong inter­molecular O—H⋯N hydrogen bonds

2,5-Dibromo­terephthalic acid dihydrate

The asymmetric unit of the title compound, C8H4Br2O4·2H2O, contains one half-mol­ecule of 2,5-dibromo­terephthalic acid (DBTA) and one water mol­ecule. The DBTA mol­ecule is centrosymmetric. In the crystal structure, inter­molecular O—H⋯O hydrogen bonds link the mol­ecules, forming a three-dimensional framework

Fully integrated InGaAs/InP single-photon detector module with gigahertz sine wave gating

InGaAs/InP single-photon avalanche diodes (SPADs) working in the regime of GHz clock rates are crucial components for the high-speed quantum key distribution (QKD). We have developed for the first time a compact, stable and user-friendly tabletop InGaAs/InP single-photon detector system operating at a 1.25 GHz gate rate that fully integrates functions for controlling and optimizing SPAD performance. We characterize the key parameters of the detector system and test the long-term stability of the system for continuous operation of 75 hours. The detector system can substantially enhance QKD performance and our present work paves the way for practical high-speed QKD applications.Comment: 11 pages, 6 figures. Accepted for publication in Review of Scientific Instrument