378 research outputs found
Almost sure convergence of maxima for chaotic dynamical systems
ArticleSuppose (f,X,ν) is a measure preserving dynamical system and ϕ:X→R is an observable with some degree of regularity. We investigate the maximum process M n :=max{X 1 ,…,X n } , where X i =ϕ∘f i is a time series of observations on the system. When M n →∞ almost surely, we establish results on the almost sure growth rate, namely the existence (or otherwise) of a sequence u n →∞ such that M n /u n →1 almost surely. The observables we consider will be functions of the distance to a distinguished point x ~ ∈X . Our results are based on the interplay between shrinking target problem estimates at x ~ and the form of the observable (in particular polynomial or logarithmic) near x ~ . We determine where such an almost sure limit exists and give examples where it does not. Our results apply to a wide class of non-uniformly hyperbolic dynamical systems, under mild assumptions on the rate of mixing, and on regularity of the invariant measure
Narrow-line Laser Cooling by Adiabatic Transfer
We propose and demonstrate a novel laser cooling mechanism applicable to
particles with narrow-linewidth optical transitions. By sweeping the frequency
of counter-propagating laser beams in a sawtooth manner, we cause adiabatic
transfer back and forth between the ground state and a long-lived optically
excited state. The time-ordering of these adiabatic transfers is determined by
Doppler shifts, which ensures that the associated photon recoils are in the
opposite direction to the particle's motion. This ultimately leads to a robust
cooling mechanism capable of exerting large forces via a weak transition and
with reduced reliance on spontaneous emission. We present a simple intuitive
model for the resulting frictional force, and directly demonstrate its efficacy
for increasing the total phase-space density of an atomic ensemble. We rely on
both simulation and experimental studies using the 7.5~kHz linewidth S
to P transition in Sr. The reduced reliance on spontaneous
emission may allow this adiabatic sweep method to be a useful tool for cooling
particles that lack closed cycling transitions, such as molecules.Comment: 5 pages, 4 figure
Development of the X-ray camera for the OGRE sub-orbital rocket
Current theories regarding the matter composition of the universe suggest that half of the expected baryonic matter is missing. One region this could be residing in is intergalactic filaments which absorb strongly in the X-ray regime. Present space based technology is limited when it comes to imaging at these wavelengths and so new techniques are required. The Off-Plane Grating Rocket Experiment (OGRE) aims to produce the highest resolution spectrum of the binary star system Capella, a well-known X-ray source, in the soft X-ray range (0.2keV to 2keV). This will be achieved using a specialised payload combining three low technology readiness level components placed on-board a sub-orbital rocket. These three components consist of an array of large format off-plane X-ray diffraction gratings, a Wolter Type 1 mirror made using single crystal silicon, and the use of EM-CCDs to capture soft X-rays. Each of these components have been previously reviewed with OGRE being the first project to utilise them in a space observation mission. This paper focuses on the EM-CCDs (CCD207-40 by e2v) that will be used and their optimisation with a camera purposely designed for OGRE. Electron Multiplying gain curves were produced for the back-illuminated devices at -80 degrees Celsius. Further tests which will need to be carried out are discussed and the impact of the OGRE mission on future projects mentioned
A decade-spanning high-resolution asynchronous optical sampling terahertz time-domain and frequency comb spectrometer
We present the design and capabilities of a high-resolution, decade-spanning ASynchronous OPtical Sampling (ASOPS)-based TeraHertz Time-Domain Spectroscopy (THz-TDS) instrument. Our system employs dual mode-locked femtosecond Ti:Sapphire oscillators with repetition rates offset locked at 100 Hz via a Phase-Locked Loop (PLL) operating at the 60th harmonic of the ∼80 MHz oscillator repetition rates. The respective time delays of the individual laser pulses are scanned across a 12.5 ns window in a laboratory scan time of 10 ms, supporting a time delay resolution as fine as 15.6 fs. The repetition rate of the pump oscillator is synchronized to a Rb frequency standard via a PLL operating at the 12th harmonic of the oscillator repetition rate, achieving milliHertz (mHz) stability. We characterize the timing jitter of the system using an air-spaced etalon, an optical cross correlator, and the phase noise spectrum of the PLL. Spectroscopic applications of ASOPS-THz-TDS are demonstrated by measuring water vapor absorption lines from 0.55 to 3.35 THz and acetonitrile absorption lines from 0.13 to 1.39 THz in a short pathlength gas cell. With 70 min of data acquisition, a 50 dB signal-to-noise ratio is achieved. The achieved root-mean-square deviation is 14.6 MHz, with a mean deviation of 11.6 MHz, for the measured water line center frequencies as compared to the JPL molecular spectroscopy database. Further, with the same instrument and data acquisition hardware, we use the ability to control the repetition rate of the pump oscillator to enable THz frequency comb spectroscopy (THz-FCS). Here, a frequency comb with a tooth width of 5 MHz is generated and used to fully resolve the pure rotational spectrum of acetonitrile with Doppler-limited precision. The oscillator repetition rate stability achieved by our PLL lock circuits enables sub-MHz tooth width generation, if desired. This instrument provides unprecedented decade-spanning, tunable resolution, from 80 MHz down to sub-MHz, and heralds a new generation of gas-phase spectroscopic tools in the THz region
A coding polymorphism in matrix metalloproteinase 9 reduces risk of scarring sequelae of ocular Chlamydia trachomatis infection.
BACKGROUND: Trachoma, an infectious disease of the conjunctiva caused by Chlamydia trachomatis, is an important global cause of blindness. A dysregulated extracellular matrix (ECM) proteolysis during the processes of tissue repair following infection and inflammation are thought to play a key role in the development of fibrotic sequelae of infection, which ultimately leads to blindness. Expression and activity of matrix metalloproteinase 9 (MMP-9), a major effector of ECM turnover, is up-regulated in the inflamed conjunctiva of trachoma subjects. Genetic variation within the MMP9 gene affects in vitro MMP9 expression levels, enzymatic activity and susceptibility to various inflammatory and fibrotic conditions. METHODS: We genotyped 651 case-control pairs from trachoma endemic villages in The Gambia for coding single nucleotide polymorphisms (SNPs) in the MMP9 gene using the high-throughput Sequenom system. Single marker and haplotype conditional logistic regression (CLR) analysis for disease association was performed. RESULTS: The Q279R mutation located in exon 6 of MMP9 was found to be associated with lower risk for severe disease sequelae of ocular Chlamydia trachomatis infection. This mutation, which leads to a nonsynonymous amino-acid change within the active site of the enzyme may reduce MMP-9-induced degradation of the structural components of the ECM during inflammatory episodes in trachoma and its associated fibrosis. CONCLUSION: This work supports the hypothesis that MMP-9 has a role in the pathogenesis of blinding trachoma
Arctic system on trajectory to new state
The Arctic system is moving toward a new state that falls outside the envelope of glacial-interglacial fluctuations that prevailed during recent Earth history. This future Arctic is likely to have dramatically less permanent ice than exists at present. At the present rate of change, a summer ice-free Arctic Ocean within a century is a real possibility, a state not witnessed for at least a million years. The change appears to be driven largely by feedback-enhanced global climate warming, and there seem to be few, if any processes or feedbacks within the Arctic system that are capable of altering the trajectory toward this “super interglacial” state
Zoonotic causes of febrile illness in malaria endemic countries:a systematic review
Fever is one of the most common reasons for seeking health care globally and most human pathogens are zoonotic. We conducted a systematic review to describe the occurrence and distribution of zoonotic causes of human febrile illness reported in malaria endemic countries. We included data from 53 (48·2%) of 110 malaria endemic countries and 244 articles that described diagnosis of 30 zoonoses in febrile people. The majority (17) of zoonoses were bacterial, with nine viruses, three protozoa, and one helminth also identified. Leptospira species and non-typhoidal salmonella serovars were the most frequently reported pathogens. Despite evidence of profound data gaps, this Review reveals widespread distribution of multiple zoonoses that cause febrile illness. Greater understanding of the epidemiology of zoonoses in different settings is needed to improve awareness about these pathogens and the management of febrile illness
Optical design of the Off-plane Grating Rocket Experiment
The Off-plane Grating Rocket Experiment (OGRE) is a soft X-ray spectroscopy suborbital rocket payload scheduled for launch in Q3 2020 from Wallops Flight Facility. The payload will serve as a testbed for several key technologies which can help achieve the desired performance increases for the next generation of X-ray spectrographs and other space-based missions: monocrystalline silicon X-ray mirrors developed at NASA Goddard Space Flight Center, reflection gratings manufactured at The Pennsylvania State University, and electron-multiplying CCDs developed by the Open University and XCAM Ltd. With these three technologies, OGRE hopes to obtain the highest-resolution on-sky soft X-ray spectrum to date. We discuss the optical design of the OGRE payload
The Off-plane Grating Rocket Experiment (OGRE) system overview
The Off-plane Grating Rocket Experiment (OGRE) is a sub-orbital rocket payload that will make the highest spectral resolution astronomical observation of the soft X-ray Universe to date. Capella, OGRE’s science target, has a well-defined line emission spectrum and is frequently used as a calibration source for X-ray observatories such as Chandra. This makes Capella an excellent target to test the technologies on OGRE, many of which have not previously flown. Through the use of state-of-the-art X-ray optics, co-aligned arrays of off-plane reflection gratings, and an X-ray camera based around four Electron Multiplying CCDs, OGRE will act as a proving ground for next generation X-ray spectrometers
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