Multiflow Transmission in Delay Constrained Cooperative Wireless Networks

This paper considers the problem of energy-efficient transmission in multi-flow multihop cooperative wireless networks. Although the performance gains of cooperative approaches are well known, the combinatorial nature of these schemes makes it difficult to design efficient polynomial-time algorithms for joint routing, scheduling and power control. This becomes more so when there is more than one flow in the network. It has been conjectured by many authors, in the literature, that the multiflow problem in cooperative networks is an NP-hard problem. In this paper, we formulate the problem, as a combinatorial optimization problem, for a general setting of $k$-flows, and formally prove that the problem is not only NP-hard but it is $o(n^{1/7-\epsilon})$ inapproxmiable. To our knowledge*, these results provide the first such inapproxmiablity proof in the context of multiflow cooperative wireless networks. We further prove that for a special case of k = 1 the solution is a simple path, and devise a polynomial time algorithm for jointly optimizing routing, scheduling and power control. We then use this algorithm to establish analytical upper and lower bounds for the optimal performance for the general case of $k$ flows. Furthermore, we propose a polynomial time heuristic for calculating the solution for the general case and evaluate the performance of this heuristic under different channel conditions and against the analytical upper and lower bounds.Comment: 9 pages, 5 figure

Joint Cache Partition and Job Assignment on Multi-Core Processors

Multicore shared cache processors pose a challenge for designers of embedded systems who try to achieve minimal and predictable execution time of workloads consisting of several jobs. To address this challenge the cache is statically partitioned among the cores and the jobs are assigned to the cores so as to minimize the makespan. Several heuristic algorithms have been proposed that jointly decide how to partition the cache among the cores and assign the jobs. We initiate a theoretical study of this problem which we call the joint cache partition and job assignment problem. By a careful analysis of the possible cache partitions we obtain a constant approximation algorithm for this problem. For some practical special cases we obtain a 2-approximation algorithm, and show how to improve the approximation factor even further by allowing the algorithm to use additional cache. We also study possible improvements that can be obtained by allowing dynamic cache partitions and dynamic job assignments. We define a natural special case of the well known scheduling problem on unrelated machines in which machines are ordered by "strength". Our joint cache partition and job assignment problem generalizes this scheduling problem which we think is of independent interest. We give a polynomial time algorithm for this scheduling problem for instances obtained by fixing the cache partition in a practical case of the joint cache partition and job assignment problem where job loads are step functions

Efficient algorithms to discover alterations with complementary functional association in cancer

Recent large cancer studies have measured somatic alterations in an unprecedented number of tumours. These large datasets allow the identification of cancer-related sets of genetic alterations by identifying relevant combinatorial patterns. Among such patterns, mutual exclusivity has been employed by several recent methods that have shown its effectivenes in characterizing gene sets associated to cancer. Mutual exclusivity arises because of the complementarity, at the functional level, of alterations in genes which are part of a group (e.g., a pathway) performing a given function. The availability of quantitative target profiles, from genetic perturbations or from clinical phenotypes, provides additional information that can be leveraged to improve the identification of cancer related gene sets by discovering groups with complementary functional associations with such targets. In this work we study the problem of finding groups of mutually exclusive alterations associated with a quantitative (functional) target. We propose a combinatorial formulation for the problem, and prove that the associated computation problem is computationally hard. We design two algorithms to solve the problem and implement them in our tool UNCOVER. We provide analytic evidence of the effectiveness of UNCOVER in finding high-quality solutions and show experimentally that UNCOVER finds sets of alterations significantly associated with functional targets in a variety of scenarios. In addition, our algorithms are much faster than the state-of-the-art, allowing the analysis of large datasets of thousands of target profiles from cancer cell lines. We show that on one such dataset from project Achilles our methods identify several significant gene sets with complementary functional associations with targets.Comment: Accepted at RECOMB 201

Single machine scheduling with controllable processing times by submodular optimization

In scheduling with controllable processing times the actual processing time of each job is to be chosen from the interval between the smallest (compressed or fully crashed) value and the largest (decompressed or uncrashed) value. In the problems under consideration, the jobs are processed on a single machine and the quality of a schedule is measured by two functions: the maximum cost (that depends on job completion times) and the total compression cost. Our main model is bicriteria and is related to determining an optimal trade-off between these two objectives. Additionally, we consider a pair of associated single criterion problems, in which one of the objective functions is bounded while the other one is to be minimized. We reduce the bicriteria problem to a series of parametric linear programs defined over the intersection of a submodular polyhedron with a box. We demonstrate that the feasible region is represented by a so-called base polyhedron and the corresponding problem can be solved by the greedy algorithm that runs two orders of magnitude faster than known previously. For each of the associated single criterion problems, we develop algorithms that deliver the optimum faster than it can be deduced from a solution to the bicriteria problem

Acerca de la predicción numérica del comportamiento de maniobra de la embarcación

A numerical procedure to predict the manoeuvrability of a ship based on Reynolds Averaged Navier Stokes simulations is described together with some recommended practices to obtain feasible results. The paper is dedicated to surface ships in unrestricted waters where usually only four degrees of freedom (DoF) are relevant. An example for a tanker shows the capability of the proposed method.Se describe un procedimiento numérico para predecir la maniobrabilidad de un buque basado en simulaciones Reynolds promediadas de Navier Stokes, así como algunas prácticas recomendadas para obtener resultados factibles. Este documento está dedicado a embarcaciones de superficie en aguas sin restricciones donde usualmente sólo cuatro grados de libertad son relevantes. Un ejemplo para un buque cisterna muestra la capacidad del método propuesto