Vertex evoked potentials in a rating-scale detection task: Relation to signal probability

Vertex evoked potentials were recorded from human subjects performing in an auditory detection task with rating scale responses. Three values of a priori probability of signal presentation were tested. The amplitudes of the N1 and P3 components of the vertex potential associated with correct detections of the signal were found to be systematically related to the strictness of the response criterion and independent of variations in a priori signal probability. No similar evoked potential components were found associated with signal absent judgements (misses and correct rejections) regardless of the confidence level of the judgement or signal probability. These results strongly support the contention that the form of the vertex evoked response is closely correlated with the subject's psychophysical decision regarding the presence or absence of a threshold level signal

A study of the reporting of patient and public involvement and engagement (PPIE) in orthodontic research

Introduction: Patient and public involvement and engagement (PPIE) in research is an essential component of high-quality research. Patients and the public can identify which research topics are most relevant to them, contribute to study design, and interpretation and dissemination of findings. While inclusion of PPIE is widely adopted in medical research, awareness within the dental research community is more limited. Aim: To examine patient and public involvement and engagement in orthodontic research activity. Design: Identification and appraisal of use of PPIE in orthodontic research reporting and funding applications using a systematic approach. Methods: Three sources of information were examined: (1) research articles published between September 2018 and September 2019 in four major orthodontic journals. Articles were examined for reported PPIE; (2) common funding bodies for orthodontic research were assessed to establish whether PPIE was mandated (National Institute for Health Research, Medical Research Council, Wellcome Trust, Chief Scientist Office (Scotland), Health and Care Research Wales, British Orthodontic Society Foundation, Royal College of Surgeons and CLEFT); and (3) publication guidance for authors in these journals was examined to identify whether reporting of PPIE was included. Results: Of the 363 research articles, 2 (0.6%) mention patient/public involvement. None of the 363 research articles mention patient/public engagement. Of nine funding bodies, 2 (22%) request evidence of patient/public involvement as a condition of receiving funding with one (11%) expecting evidence of public engagement to be provided as a condition of receiving funding. None of the four major orthodontic journals include patient/public involvement and/or engagement in their guidance for authors. Conclusion: There is currently: (1) a notable lack of reporting of PPIE in orthodontic research; (2) variability in the requirements of funding bodies for researchers to include PPIE in funding applications and throughout the research process; and (3) no stipulation in journals’ instructions for authors

Parallel attentional facilitation of features and objects in early visual cortex

Selective attention can enhance the processing of attended features across the entire visual field. Attention also spreads within objects, enhancing all internal locations and task-irrelevant features of selected objects. Here, we examine the extent to which attentional enhancement of a feature spreads across attended and unattended objects. Two fully overlapping counter-rotating bicolored surfaces of light and dark random dots were presented on a gray background of intermediate luminance. This stimulus creates a percept of two separate semitransparent surfaces and allows the measurement of feature- and object-based selections while controlling spatial attention. On each trial, human participants attended to a subset of dots defined by feature (luminance polarity) and object (surface) in order to detect brief episodes of radial motion while ignoring any events in the unattended groups of dots. Attentional selection was assessed by means of steady-state visual evoked potentials (SSVEPs) and behavioral measures. SSVEP amplitudes recorded at medial occipital electrode sites were modulated both by surface-based and luminance polarity-based selection in a manner consistent with independent multiplicative enhancement of attentional effects in different dimensions in early visual cortex. This finding supports the view that feature-based attention spreads across object boundaries, at least at an early stage of processing. However, SSVEPs elicited at more lateral electrode sites showed a hierarchical pattern of selection, potentially reflecting the binding of surface-defining features with luminance features to enable surface-based attention

Effects of dried distillers grains with solubles on sow carcass fat quality

A pilot experiment was conducted to determine the effects of feeding nonpregnant (open) sows a diet containing 50% dried distillers grains with solubles (DDGS) on growth and carcass fat quality. A total of 8 open sows were allotted to 1 of 2 diets by parity and BW. One diet was a standard corn-soybean meal-based gestation diet; the second diet was a corn-soybean meal-based diet that contained 50% DDGS. All sows were fed 5 lb/d of feed in a single feeding for 92 d. All sows were harvested on d 92 at the Kansas State University Meat Laboratory for determination of carcass fat quality. As expected, no differences in BW or backfat change were found (P \u3e 0.62) for the feeding period. Additionally, no differences (P \u3e 0.23) in lipid oxidation as measured by 2-thiobarbituric acid reactive substances (TBARS) assay were reported either initially or after 5 d of retail display for sows fed 50% DDGS compared with controls. Lipid oxidation increased (P \u3c 0.003) as measured by TBARS assay for both treatments from d 1 to 5 as expected. Jowl fatty acid analysis revealed an increase in linoleic acid (P \u3c 0.01), total polyunsaturated fatty acids (P \u3c 0.01), and the ratio of polyunsaturated fatty acids to saturated fatty acids (P \u3c 0.03). Also, there was a trend for increased jowl iodine value (P \u3c 0.08) for sows fed 50% DDGS compared with the controls. In summary, feeding 50% DDGS to open sows for 92 d did not significantly affect BW, backfat, and lipid oxidation compared with controls. However, feeding 50% DDGS increased the concentration of linoleic acid and total polyunsaturated fatty acids and tended to increase jowl iodine value compared with controls.; Swine Day, 2008, Kansas State University, Manhattan, KS, 200

Beliefs about the Minds of Others Influence How We Process Sensory Information

Attending where others gaze is one of the most fundamental mechanisms of social cognition. The present study is the first to examine the impact of the attribution of mind to others on gaze-guided attentional orienting and its ERP correlates. Using a paradigm in which attention was guided to a location by the gaze of a centrally presented face, we manipulated participants' beliefs about the gazer: gaze behavior was believed to result either from operations of a mind or from a machine. In Experiment 1, beliefs were manipulated by cue identity (human or robot), while in Experiment 2, cue identity (robot) remained identical across conditions and beliefs were manipulated solely via instruction, which was irrelevant to the task. ERP results and behavior showed that participants' attention was guided by gaze only when gaze was believed to be controlled by a human. Specifically, the P1 was more enhanced for validly, relative to invalidly, cued targets only when participants believed the gaze behavior was the result of a mind, rather than of a machine. This shows that sensory gain control can be influenced by higher-order (task-irrelevant) beliefs about the observed scene. We propose a new interdisciplinary model of social attention, which integrates ideas from cognitive and social neuroscience, as well as philosophy in order to provide a framework for understanding a crucial aspect of how humans' beliefs about the observed scene influence sensory processing

Neural Correlates of Auditory Perceptual Awareness under Informational Masking

Our ability to detect target sounds in complex acoustic backgrounds is often limited not by the ear's resolution, but by the brain's information-processing capacity. The neural mechanisms and loci of this “informational masking” are unknown. We combined magnetoencephalography with simultaneous behavioral measures in humans to investigate neural correlates of informational masking and auditory perceptual awareness in the auditory cortex. Cortical responses were sorted according to whether or not target sounds were detected by the listener in a complex, randomly varying multi-tone background known to produce informational masking. Detected target sounds elicited a prominent, long-latency response (50–250 ms), whereas undetected targets did not. In contrast, both detected and undetected targets produced equally robust auditory middle-latency, steady-state responses, presumably from the primary auditory cortex. These findings indicate that neural correlates of auditory awareness in informational masking emerge between early and late stages of processing within the auditory cortex

Crime or social harm? A dialectical perspective

This paper proposes to examine some of the core philosophical issues to have arisen out of the recent calls to move "beyond criminology". It will be claimed that the dismissal of crime as a "fictive event" is premature, as crime does indeed have an "ontological reality". Nevertheless, it will be asserted that the relation between harm and crime is contingent rather than necessary. Accordingly, this paper will argue that there is merit to the claim that we should unify research on social harm through the creation of a new field, a step which would have the added benefit of constructing an alternative venue for crimes of the powerful scholars who wish to explore the destructive practices of states and corporations unconstrained. This paper, therefore, will also offer a dialectical definition of social harm based upon classical Marxist strains of ontological thought

Family stories, public silence: Irish identity construction amongst the second-generation Irish in England

Formal narratives of history, especially that of colonial oppression, have been central to the construction of national identities in Ireland. But the Irish diasporic community in Britain has been cut off from the reproduction of these narratives, most notably by their absence from the curriculum of Catholic schools, as result of the unofficial 'denationalisation' pact agreed by the Church in the 19th century (Hickman, 1995). The reproduction of Irish identities is largely a private matter, carried out within the home through family accounts of local connections, often reinforced by extended visits to parent/s 'home' areas. Recapturing a public dimension has often become a personal quest in adulthood, 'filling in the gaps'. This paper explores constructions of narratives of nation by a key diasporic population, those with one or two Irish-born parents. It places particular emphasis on varying regional/national contexts within which such constructions take place, drawing on focus group discussions and interviews for the ESRC-funded Irish 2 Project in five locations — London, Glasgow, Manchester, Coventry and Banbury

The N2cc component as an electrophysiological marker of space-based and feature-based attentional target selection processes in touch

An electrophysiological correlate of attentional target selection processes in touch (N2cc component) has recently been discovered in lateralized tactile working memory experiments. This tactile N2cc emerges at the same time as the visual N2pc component, but has a different modality-specific topography over central somatosensory areas. Here, we investigated links between N2cc components and the space-based versus feature-based attentional selection of task-relevant tactile stimuli. On each trial, a pair of tactile items was presented simultaneously to one finger on the left and right hand. Target stimuli were defined by their location (e.g., left index finger; Spatial Attention Task), by a non-spatial feature (continuous versus pulsed; Feature-based Attention Task), or by a combination of spatial and non-spatial features (Conjunction Task). Reliable N2cc components were observed in all three tasks. They emerged considerably earlier in the Spatial Attention Task than in the Feature-based Attention Task, suggesting that space-based selection mechanisms in touch operate faster than feature-guided mechanisms. The temporal pattern of N2cc components observed in the Conjunction Task revealed that space-based and feature-based attention both contributed to target selection, which was initially driven primarily by spatial location. Overall, these findings establish the N2cc component as a new electrophysiological marker of the selective attentional processing of task-relevant stimuli in touch