End diastolic and end systolic contours of the left ventricle.

<p>Effect of I/R in the MR16-1 and control IgG groups on cardiac function as measured by Cardiac Magnetic Resonance Imaging and visualized with mean and standard deviation; (A) Average case of the control IgG I/R group with end systolic and end diastolic contours, volumes and LVEF (LVESV 57 μl, LVEDV 85 μl, LVEF 32%); (B) Average case of the MR16-1 treatment I/R group with end systolic and end diastolic contours, volumes and LVEF (LVESV 60 μl, LVEDV 81 μl, LVEF 26%); (C) Average case of the IgG sham group with end systolic and end diastolic contours, volumes and LVEF (LVESV 32 μl, LVEDV 56 μl, LVEF 43%); (D) Average case of the MR16-1 sham group with end systolic and end diastolic contours, volumes and LVEF (LVESV 33 μl, LVEDV 60 μl, LVEF 44%).</p

Organ weights and histology 28 days after surgery.

<p>Organ weights and histology 28 days after surgery.</p

Fibrosis and hypertrophy.

<p>Effect of I/R vs. sham in the MR16-1 and IgG groups on percentage of fibrosis and cell size and visualized with mean and standard deviation; I/R resulted in an increase in the percentage of fibrosis, however there was no effect of MR16-1 vs. IgG among these groups (A); No effect on cell size was observed in all groups (B).</p

Cardiac function, LV and aortic pressures 28 days after surgery.

<p>Cardiac function, LV and aortic pressures 28 days after surgery.</p

Additional file 4 of Identification of genetic variants that impact gene co-expression relationships using large-scale single-cell data

Additional file 4: Table S3. eQTLs for major cell types

Additional file 12 of Identification of genetic variants that impact gene co-expression relationships using large-scale single-cell data

Additional file 12: Table S17. Enrichment of co-eGenes for GWAS result

Additional file 6 of Identification of genetic variants that impact gene co-expression relationships using large-scale single-cell data

Additional file 6: Table S9. BIOS replication for filtered co-eQTLs for major cell types

Additional file 2 of Identification of genetic variants that impact gene co-expression relationships using large-scale single-cell data

Additional file 2: Supplementary Figures. Collection of all Fig. S1-34

Additional file 8 of Identification of genetic variants that impact gene co-expression relationships using large-scale single-cell data

Additional file 8: Table S13. BIOS replication for unfiltered co-eQTLs for major cell type

Additional file 3 of Identification of genetic variants that impact gene co-expression relationships using large-scale single-cell data

Additional file 3: Supplementary Note. More extensive description of meta-cell evaluation, alternative GRN construction methods and interpretation of additional co-eQTL examples