ÁREAS DE DESARROLLO ENTRE LA GESTIÓN DE LA COMUNICACIÓN INSTITUCIONAL Y LA GESTIÓN DEL CONOCIMIENTO

En pleno auge de la sociedad en red, áreas prácticas y académicas de alto impacto en su progreso, como la gestión de la comunicación institucional y la gestión del conocimiento, exhiben diálogos tenues que hacen peligrar su importante papel en el desarrollo organizacional. Múltiples causas generan tales comportamientos, y sobre ello en Cuba ya se viene investigando y trabajando. El presente artículo de revisión bibliográfica, establece la existencia de una relación entre la gestión de la comunicación institucional y la gestión del conocimiento, la cual se hace visible en dimensiones objetivables en zonas de prácticas y conceptos que se identifican desde ambos lados del saber, pero que necesitan situarse en una ineludible demarcación que haga visible sus convergencias, más que las diferencias. Esto es necesario para potenciar la gestión de valores intangibles esenciales y lograr la eficiencia de la gestión organizacional que se requiere en la actualidad. También permite argumentar la relación interdisciplinaria que tiene lugar entre la gestión de la comunicación institucional y del conocimiento, y con ello contribuir a diálogos académicos más enriquecedores. Así quedan plasmadas y justificadas cinco áreas de desarrollo y criterios que permiten examinar y fomentar la citada relación

From cacti to carnivores: Improved phylotranscriptomic sampling and hierarchical homology inference provide further insight into the evolution of Caryophyllales

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/143660/1/ajb21069.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/143660/2/ajb21069_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/143660/3/ajb21069-sup-0002-AppendixS2.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/143660/4/ajb21069-sup-0005-AppendixS5.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/143660/5/ajb21069-sup-0001-AppendixS1.pd

Cumplimiento de planes de medidas de la Red de Bibliotecas en la Atención Primaria de Salud de Guantánamo

A diagnostic analysis is carried out in the libraries belonging to polyclinics and rural hospitals in Guantanamo province, with the objective of knowing the main difficulties in terms of organization, process evaluation, administrative control and methodological control in these units. The universe and sample consisted of the 20 libraries of Primary Health Care (PHC). The applied diagnosis consisted of three annexes: a questionnaire, inventory of the minimum funds and instructions for its filling. Once the main difficulties were identified, action plans were established with their respective managers and complianceSe realiza un análisis diagnóstico en las bibliotecas pertenecientes a los policlínicos y hospitales rurales de la provincia Guantánamo, con el objetivo de conocer las principales dificultades en cuanto a lo organizativo, evaluación de procesos, control administrativo y control metodológico en estas unidades. El universo y muestra estuvo constituido por las 20 bibliotecas de la Atención Primaria de Salud (APS). El diagnóstico aplicado estuvo formado por tres anexos: un cuestionario, inventario de los fondos mínimos y las instrucciones para su llenado. Una vez identificadas las principales dificultades, se establecieron planes de medidas con sus respectivos responsables y fechas de cumplimiento.

Cumplimiento de planes de medidas de la Red de Bibliotecas en la Atención Primaria de Salud de Guantánamo

A diagnostic analysis is carried out in the libraries belonging to polyclinics and rural hospitals in Guantanamo province, with the objective of knowing the main difficulties in terms of organization, process evaluation, administrative control and methodological control in these units. The universe and sample consisted of the 20 libraries of Primary Health Care (PHC). The applied diagnosis consisted of three annexes: a questionnaire, inventory of the minimum funds and instructions for its filling. Once the main difficulties were identified, action plans were established with their respective managers and complianceSe realiza un análisis diagnóstico en las bibliotecas pertenecientes a los policlínicos y hospitales rurales de la provincia Guantánamo, con el objetivo de conocer las principales dificultades en cuanto a lo organizativo, evaluación de procesos, control administrativo y control metodológico en estas unidades. El universo y muestra estuvo constituido por las 20 bibliotecas de la Atención Primaria de Salud (APS). El diagnóstico aplicado estuvo formado por tres anexos: un cuestionario, inventario de los fondos mínimos y las instrucciones para su llenado. Una vez identificadas las principales dificultades, se establecieron planes de medidas con sus respectivos responsables y fechas de cumplimiento.

Tumor masses support naive T cell infiltration, activation, and differentiation into effectors

Studies of T cell responses to tumors have focused on the draining lymph node (LN) as the site of activation. We examined the tumor mass as a potential site of activation after adoptive transfer of naive tumor-specific CD8 T cells. Activated CD8 T cells were present in tumors within 24 h of adoptive transfer and proliferation of these cells was also evident 4–5 d later in mice treated with FTY720 to prevent infiltration of cells activated in LNs. To confirm that activation of these T cells occurred in the tumor and not the tumor-draining LNs, we used mice lacking LNs. Activated and proliferating tumor-infiltrating lymphocytes were evident in these mice 24 h and 4 d after naive cell transfer. T cells activated within tumors acquired effector function that was evident both ex vivo and in vivo. Both cross-presenting antigen presenting cells within the tumor and tumor cells directly presenting antigen activated these functional CD8 effectors. We conclude that tumors support the infiltration, activation, and effector differentiation of naive CD8 T cells, despite the presence of immunosuppressive mechanisms. Thus, targeting of T cell activation to tumors may present a tool in the development of cancer immunotherapy

Conserved CDC20 Cell Cycle Functions Are Carried out by Two of the Five Isoforms in Arabidopsis thaliana

The CDC20 and Cdh1/CCS52 proteins are substrate determinants and activators of the Anaphase Promoting Complex/Cyclosome (APC/C) E3 ubiquitin ligase and as such they control the mitotic cell cycle by targeting the degradation of various cell cycle regulators. In yeasts and animals the main CDC20 function is the destruction of securin and mitotic cyclins. Plants have multiple CDC20 gene copies whose functions have not been explored yet. In Arabidopsis thaliana there are five CDC20 isoforms and here we aimed at defining their contribution to cell cycle regulation, substrate selectivity and plant development.Studying the gene structure and phylogeny of plant CDC20s, the expression of the five AtCDC20 gene copies and their interactions with the APC/C subunit APC10, the CCS52 proteins, components of the mitotic checkpoint complex (MCC) and mitotic cyclin substrates, conserved CDC20 functions could be assigned for AtCDC20.1 and AtCDC20.2. The other three intron-less genes were silent and specific for Arabidopsis. We show that AtCDC20.1 and AtCDC20.2 are components of the MCC and interact with mitotic cyclins with unexpected specificity. AtCDC20.1 and AtCDC20.2 are expressed in meristems, organ primordia and AtCDC20.1 also in pollen grains and developing seeds. Knocking down both genes simultaneously by RNAi resulted in severe delay in plant development and male sterility. In these lines, the meristem size was reduced while the cell size and ploidy levels were unaffected indicating that the lower cell number and likely slowdown of the cell cycle are the cause of reduced plant growth.The intron-containing CDC20 gene copies provide conserved and redundant functions for cell cycle progression in plants and are required for meristem maintenance, plant growth and male gametophyte formation. The Arabidopsis-specific intron-less genes are possibly "retrogenes" and have hitherto undefined functions or are pseudogenes