6 research outputs found
Lanthanide complexes as imaging agents anchored on nano-sized particles of boehmite
The synthesis of boehmite nanoparticles modified with lanthanides (Eu, Tb and Gd) is described. Their
synthesis, characterization and in vitro assays with HeLa cells were performed. The nuclear magnetic
relaxation dispersion (NMRD) profiles of the two chelating moieties were studied. Imaging data from
laser scanning confocal fluorescence microscopy and flow cytometry revealed that the nanoscaffolds
were taken up by the cells, distributed throughout the cytoplasm and showed no toxicity. This platform
could represent an alternative to silica-based inert matrices as imaging vehicles.MCINN for a predoctoral FPU fellowship, for a Juan de la Cierva contract. Ayuntamiento deValencia for theCarmen y Severo Ochoa Fellowship