Oral health and mental health in healthy adults, a topic of primary prevention and health care, empirical results from two online studies

Oral health is an important, yet often neglected aspect of health and well-being. Among geriatric populations, oral diseases, poor oral health, and reduced oral hygiene behavior are major comorbid factors of geriatric diseases such as dementia, cardiovascular diseases, or mental health conditions. However, little is known so far about the relationships between oral health and mental health in the younger adult population, who is yet not suffering from any disorder. In the present manuscript the results of two online studies, online study 1, n = 133, all-female sample and online study 2: n = 29, mixed gender sample, are reported that investigate the relationship between self-reported oral health impairments and preclinical symptoms of mental disorders including self-reported symptoms associated with depression or eating disorders as well as self-reported perceived stress and behavior change related to the COVID-19 pandemic. The results of both studies support links between self-reported oral health impairments, self-reported depressive symptoms (including anxiety and current affect) and symptoms related to eating disorders (such as bulimic behavior, body dissatisfaction or drive for thinness) among young adults and suggest that perceived stress may contribute to both, impaired oral health and impaired mental health in young adults (women and men)

Emotional facial expressions evoke faster orienting responses, but weaker emotional responses at neural and behavioural levels compared to scenes: A simultaneous EEG and facial EMG study

AbstractIn the current study, electroencephalography (EEG) was recorded simultaneously with facial electromyography (fEMG) to determine whether emotional faces and emotional scenes are processed differently at the neural level. In addition, it was investigated whether these differences can be observed at the behavioural level via spontaneous facial muscle activity. Emotional content of the stimuli did not affect early P1 activity. Emotional faces elicited enhanced amplitudes of the face-sensitive N170 component, while its counterpart, the scene-related N100, was not sensitive to emotional content of scenes. At 220–280ms, the early posterior negativity (EPN) was enhanced only slightly for fearful as compared to neutral or happy faces. However, its amplitudes were significantly enhanced during processing of scenes with positive content, particularly over the right hemisphere. Scenes of positive content also elicited enhanced spontaneous zygomatic activity from 500–750ms onwards, while happy faces elicited no such changes. Contrastingly, both fearful faces and negative scenes elicited enhanced spontaneous corrugator activity at 500–750ms after stimulus onset. However, relative to baseline EMG changes occurred earlier for faces (250ms) than for scenes (500ms) whereas for scenes activity changes were more pronounced over the whole viewing period. Taking into account all effects, the data suggests that emotional facial expressions evoke faster attentional orienting, but weaker affective neural activity and emotional behavioural responses compared to emotional scenes

Brain-computer interfaces and human factors: the role of language and cultural differences—Still a missing gap?

Brain-computer interfaces (BCIs) aim at the non-invasive investigation of brain activity for supporting communication and interaction of the users with their environment by means of brain-machine assisted technologies. Despite technological progress and promising research aimed at understanding the influence of human factors on BCI effectiveness, some topics still remain unexplored. The aim of this article is to discuss why it is important to consider the language of the user, its embodied grounding in perception, action and emotions, and its interaction with cultural differences in information processing in future BCI research. Based on evidence from recent studies, it is proposed that detection of language abilities and language training are two main topics of enquiry of future BCI studies to extend communication among vulnerable and healthy BCI users from bench to bedside and real world applications. In addition, cultural differences shape perception, actions, cognition, language and emotions subjectively, behaviorally as well as neuronally. Therefore, BCI applications should consider cultural differences in information processing to develop culture- and language-sensitive BCI applications for different user groups and BCIs, and investigate the linguistic and cultural contexts in which the BCI will be used

Analyzing and computing humans by means of the brain using Brain-Computer Interfaces - understanding the user – previous evidence, self-relevance and the user’s self-concept as potential superordinate human factors of relevance

Brain–computer interfaces (BCIs) are well-known instances of how technology can convert a user’s brain activity taken from non-invasive electroencephalography (EEG) into computer commands for the purpose of computer-assisted communication and interaction. However, not all users are attaining the accuracy required to use a BCI consistently, despite advancements in technology. Accordingly, previous research suggests that human factors could be responsible for the variance in BCI performance among users. Therefore, the user’s internal mental states and traits including motivation, affect or cognition, personality traits, or the user’s satisfaction, beliefs or trust in the technology have been investigated. Going a step further, this manuscript aims to discuss which human factors could be potential superordinate factors that influence BCI performance, implicitly, explicitly as well as inter- and intraindividually. Based on the results of previous studies that used comparable protocols to examine the motivational, affective, cognitive state or personality traits of healthy and vulnerable EEG-BCI users within and across well-investigated BCIs (P300-BCIs or SMR-BCIs, respectively), it is proposed that the self-relevance of tasks and stimuli and the user’s self-concept provide a huge potential for BCI applications. As potential key human factors self-relevance and the user’s self-concept (self-referential knowledge and beliefs about one’s self) guide information processing and modulate the user’s motivation, attention, or feelings of ownership, agency, and autonomy. Changes in the self-relevance of tasks and stimuli as well as self-referential processing related to one’s self (self-concept) trigger changes in neurophysiological activity in specific brain networks relevant to BCI. Accordingly, concrete examples will be provided to discuss how past and future research could incorporate self-relevance and the user’s self-concept in the BCI setting – including paradigms, user instructions, and training sessions

Approach and withdrawal tendencies during written word processing: effects of task, emotional valence and emotional arousal

The affective dimensions of emotional valence and emotional arousal affect processing of verbal and pictorial stimuli. Traditional emotional theories assume a linear relationship between these dimensions, with valence determining the direction of a behaviour (approach vs. withdrawal) and arousal its intensity or strength. In contrast, according to the valence-arousal conflict theory, both dimensions are interactively related: positive valence and low arousal (PL) are associated with an implicit tendency to approach a stimulus, whereas negative valence and high arousal (NH) are associated with withdrawal. Hence, positive, high-arousal (PH) and negative, low-arousal (NL) stimuli elicit conflicting action tendencies. By extending previous research that used several tasks and methods, the present study investigated whether and how emotional valence and arousal affect subjective approach vs. withdrawal tendencies towards emotional words during two novel tasks. In Study 1, participants had to decide whether they would approach or withdraw from concepts expressed by written words. In Studies 2 and 3 participants had to respond to each word by pressing one of two keys labelled with an arrow pointing upward or downward. Across experiments, positive and negative words, high or low in arousal, were presented. In Study 1 (explicit task), in line with the valence-arousal conflict theory, PH and NL words were responded to more slowly than PL and NH words. In addition, participants decided to approach positive words more often than negative words. In Studies 2 and 3, participants responded faster to positive than negative words, irrespective of their level of arousal. Furthermore, positive words were significantly more often associated with "up" responses than negative words, thus supporting the existence of implicit associations between stimulus valence and response coding (positive is up and negative is down). Hence, in contexts in which participants’ spontaneous responses are based on implicit associations between stimulus valence and response, there is no influence of arousal. In line with the valence-arousal conflict theory arousal seems to affect participants’ approach-withdrawal tendencies only when such tendencies are made explicit by the task, and a minimal degree of processing depth is required

Effects of Task, Emotional Valence, and Emotional Arousal

The affective dimensions of emotional valence and emotional arousal affect processing of verbal and pictorial stimuli. Traditional emotional theories assume a linear relationship between these dimensions, with valence determining the direction of a behavior (approach vs. withdrawal) and arousal its intensity or strength. In contrast, according to the valence-arousal conflict theory, both dimensions are interactively related: positive valence and low arousal (PL) are associated with an implicit tendency to approach a stimulus, whereas negative valence and high arousal (NH) are associated with withdrawal. Hence, positive, high-arousal (PH) and negative, low-arousal (NL) stimuli elicit conflicting action tendencies. By extending previous research that used several tasks and methods, the present study investigated whether and how emotional valence and arousal affect subjective approach vs. withdrawal tendencies toward emotional words during two novel tasks. In Study 1, participants had to decide whether they would approach or withdraw from concepts expressed by written words. In Studies 2 and 3 participants had to respond to each word by pressing one of two keys labeled with an arrow pointing upward or downward. Across experiments, positive and negative words, high or low in arousal, were presented. In Study 1 (explicit task), in line with the valence-arousal conflict theory, PH and NL words were responded to more slowly than PL and NH words. In addition, participants decided to approach positive words more often than negative words. In Studies 2 and 3, participants responded faster to positive than negative words, irrespective of their level of arousal. Furthermore, positive words were significantly more often associated with “up” responses than negative words, thus supporting the existence of implicit associations between stimulus valence and response coding (positive is up and negative is down). Hence, in contexts in which participants' spontaneous responses are based on implicit associations between stimulus valence and response, there is no influence of arousal. In line with the valence-arousal conflict theory, arousal seems to affect participants' approach-withdrawal tendencies only when such tendencies are made explicit by the task, and a minimal degree of processing depth is required

Response Inhibition and Memory Retrieval of Emotional Target Words: Evidence from an Emotional Stop-Signal Task

Previous research suggests that emotional stimuli capture attention and guide behavior often automatically. The present study investigated the relationship between emotion-driven attention capture and motor response inhibition to emotional words in the stop-signal task. By experimental variations of the onset of motor response inhibition across the time-course of emotional word processing, we show that processing of emotional information significantly interferes with motor response inhibition in an early time-window, previously related to automatic emotion-driven attention capture. Second, we found that stopping reduced memory recall for unpleasant words during a subsequent surprise free recall task supporting assumptions of a link between mechanisms of motor response inhibition and memory functions. Together, our results provide behavioral evidence for dual competition models of emotion and cognition. This study provides an important link between research focusing on different sub-processes of emotion processing (from perception to action and from action to memory)

Wissenschaftsläden als Informationslotsen im Rahmen der Verbraucherbildung für nachhaltige Entwicklung

Die Arbeit als Informationslotsen für Bürger/-innen und Verbraucher/-innen gehört zu den Kernaktivitäten von Wissenschaftsläden. Ihnen wird ein hohes Maß an Glaubwürdigkeit und methodischer Expertise beim Transfer von wissenschaftlichen Erkenntnissen zum Bürger zugeschrieben. Der Beitrag stellt Erfahrungen dieser Mittlertätigkeit anhand verschiedener Projekte und Methoden dar, die in der Praxis des Wissenschaftsladens Bonn Anwendung finden, um Menschen zum nachhaltigen Handeln zu bewegen

Progressive retinal degeneration and glial activation in the Cln6nclf mouse model of neuronal ceroid lipofuscinosis : a beneficial effect of DHA and Curcumin supplementation

Neuronal ceroid lipofuscinosis (NCL) is a group of neurodegenerative lysosomal storage disorders characterized by vision loss, mental and motor deficits, and spontaneous seizures. Neuropathological analyses of autopsy material from NCL patients and animal models revealed brain atrophy closely associated with glial activity. Earlier reports also noticed loss of retinal cells and reactive gliosis in some forms of NCL. To study this phenomenon in detail, we analyzed the ocular phenotype of CLN6nclf mice, an established mouse model for variant-late infantile NCL. Retinal morphometry, immunohistochemistry, optokinetic tracking, electroretinography, and mRNA expression were used to characterize retinal morphology and function as well as the responses of Müller cells and microglia. Our histological data showed a severe and progressive degeneration in the CLN6nclf retina co-inciding with reactive Müller glia. Furthermore, a prominent phenotypic transformation of ramified microglia to phagocytic, bloated, and mislocalized microglial cells was identified in CLN6nclf retinas. These events overlapped with a rapid loss of visual perception and retinal function. Based on the strong microglia reactivity we hypothesized that dietary supplementation with immuno-regulatory compounds, curcumin and docosahexaenoic acid (DHA), could ameliorate microgliosis and reduce retinal degeneration. Our analyses showed that treatment of three-week-old CLN6nclf mice with either 5% DHA or 0.6% curcumin for 30 weeks resulted in a reduced number of amoeboid reactive microglia and partially improved retinal function. DHA-treatment also improved the morphology of CLN6nclf retinas with a preserved thickness of the photoreceptor layer in most regions of the retina. Our results suggest that microglial reactivity closely accompanies disease progression in the CLN6nclf retina and both processes can be attenuated with dietary supplemented immuno-modulating compounds