The Indigenous history and colonial politics of Torres Strait: contesting culture and resources from 1867 to 1990

The aim of my study is to comprehend why there is a significant gap in the economic development of Torres Strait. It questions why it is that Torres Strait Islanders as a whole remain largely economically unproductive in their present situation in contrast to the political beliefs of Islanders and their struggles for self-determination. It questions why Island leaders continue to accept policies of external control even though the guidelines for self development maintain the situation, rather than transforming it. Thus this thesis examines contemporary and traditional history of the Torres Strait in order to analyse and evaluate the development of the political structures of the Islands and how colonialism has influenced the politics of Torres Strait Islanders. I shift through the recorded layers of myths and legends for my interpretation and analyse the ethnographic accounts about Torres Strait from past archival reports, academic literature and the oral accounts from interviews. From the local media, I have examined the recent views of both the contented and discontented Islanders and other people reported in the local Torres News. From these records, I bring into perspective the historical processes of a capitalist economic system which has so deeply penetrated Islander culture.Commencing in the 1860s, at the onset of the Torres Strait beche-de-mer and pearl shell industry, the system has so failed Torres Strait Islanders' social development that it moved Islander leaders in the 1980s to push for cessation from Australia and, in the mid 1900s to seek "autonomy and self government" to remain within the Australian political system. In this thesis, I use this evidence to bring into perspective the concept of development with awareness to the colonial history of Torres Strait in comparison with oral history interpreted as the culture of my people. The theme my thesis implicates the contestation between Torres Strait Islanders and governments who impose administrative policies through the Islander system of political representation (regarding Islander culture and resources)

The 3rd Annual Lady Grace Revere Osler Lecture in Surgical Quality

Optimal Pancreatic Surgery At the conclusion of this presentation the participant should be able to: 1. Understand the role of hospital and surgeon volume in pancreatic surgery 2. Report the relative risk of various pancreatic operations 3. Acknowledge the importance of chain management in outcomes. Presentation: 57 minute

The world significance of the Russian revolution

https://stars.library.ucf.edu/prism/1673/thumbnail.jp

Values, axial currencies, and computational axiology: digital currencies can do more than buy stuff

Eleven to twelve thousand years ago, early humans lived in small communities with no discernible hierarchy. The "agrarian revolution" resulted in communities growing on such a scale that mechanisms of self-organization - e.g., for monitoring, keeping order, and ensuring a "satisfactory" allocation of resources - were no longer efficient or effective. However, the concurrent "cognitive" revolution resulted in the faculty of imagination, in particular, the imagination of rules, to solve such problems

An Analysis of Infectious Failures in Acute Cholangitis

To determine the factors responsible for therapeutic failures in acute cholangitis, a series of 127 patients was analyzed. There were 64 females and 63 males whose mean age was 57.2 years. Ninetyfour (74.0%) of these patients were clinically cured with initial measures, whereas 33 patients (26%) failed initial therapy for an infectious reason. No differences were observed between the two groups in regard to age and gender. However, more patients in the group that failed had a malignant cause for their bile duct obstruction (72.7% vs. 42.6%, p < 0.01) and had a pretreatment positive blood culture (45.5% vs. 13.8%, p < 0.01). Patients who failed had a higher mean total bilirubin level (9.7 mg/dl vs. 5.5 mg/dl, p < 0.005) and more of them had a level greater than 2.2 mg/dl (97% vs. 69.9%, p < 0.001). Also, more bile cultures were initially positive (93.9% vs. 76.6%, p < 0.05) and more organisms were isolated per culture (3.88 vs. 2.86, p < 0.03) in the patients who failed. In addition, more patients failed who had two or more organisms in the bile (33% vs. 8.3%, p < 0.02). Patients in whom Candida, or any panresistant organism was isolated also tended to fail. Multivariant analysis showed that malignancy, bacteremia, bilirubin ≥ 2.2 mg/dl, ≥ 2 organisms in the bile and a panresistant organism were the best predictors of treatment failure with a serum bilirubin level ≥ 2.2 mg/dl being the variable that increases a patient's log-odds ratio of failure the greatest. In conclusion, patients with acute cholangitis who have an increased chance to fail initial therapy can be identified, and treatment altered accordingly

Adipocytes enhance murine pancreatic cancer growth via a hepatocyte growth factor (HGF)-mediated mechanism

INTRODUCTION: Obesity accelerates the development and progression of pancreatic cancer, though the mechanisms underlying this association are unclear. Adipocytes are biologically active, producing factors such as hepatocyte growth factor (HGF) that may influence tumor progression. We therefore sought to test the hypothesis that adipocyte-secreted factors including HGF accelerate pancreatic cancer cell proliferation. MATERIAL AND METHODS: Murine pancreatic cancer cells (Pan02 and TGP-47) were grown in a) conditioned medium (CM) from murine F442A preadipocytes, b) HGF-knockdown preadipocyte CM, c) recombinant murine HGF at increasing doses, and d) CM plus HGF-receptor (c-met) inhibitor. Cell proliferation was measured using the MTT assay. ANOVA and t-test were applied; p < 0.05 considered significant. RESULTS: Wild-type preadipocyte CM accelerated Pan02 and TGP-47 cell proliferation relative to control (59 ± 12% and 34 ± 12%, p < 0.01, respectively). Knockdown of preadipocyte HGF resulted in attenuated proliferation vs. wild type CM in Pan02 cells (35 ± 5% vs. 68 ± 14% greater than control; p < 0.05), but proliferation in TGP-47 cells remained unchanged. Recombinant HGF dose-dependently increased Pan02, but not TGP-47, proliferation (p < 0.05). Inhibition of HGF receptor, c-met, resulted in attenuated proliferation versus control in Pan02 cells, but not TGP-47 cells. CONCLUSIONS: These experiments demonstrate that adipocyte-derived factors accelerate murine pancreatic cancer proliferation. In the case of Pan02 cells, HGF is responsible, in part, for this proliferation

Leakage of an invagination pancreaticojejunostomy may have an influence on mortality

Purpose: No consensus exists regarding the most effective form of pancreaticojejunostomy (PJ) following pancreaticoduodenectomy (PD). Methods: Data were gathered through the American College of Surgeons-National Surgical Quality Improvement Program, Pancreatectomy Demonstration Project. A total of 1781 patients underwent a PD at 43 institutions. After appropriate exclusions, 890 patients were analyzed. Patients were divided into duct-to-mucosa (n = 734, 82%) and invagination (n = 156, 18%) groups and were compared by unadjusted analysis. Type of PJ was included in eight separate morbidity and mortality multivariable analyses. Results: Invagination patients had higher serum albumin (p &lt; 0.01) and lower body mass index (p &lt; 0.01), were less likely to have a preoperative biliary stent (p &lt; 0.01), and were more likely to have a soft gland (p &lt; 0.01). PJ anastomosis type was not associated with morbidity but was associated with mortality (duct-to-mucosa vs. invagination, odds ratio = 0.22, p &lt; 0.01). Among patients who developed a clinically relevant pancreatic fistula, none of the 119 duct-to-mucosa, compared with 5 of 21 invagination, patients died (p &lt; 0.01). Conclusion: Patients who undergo a PJ by duct-to-mucosa or invagination differ with respect to preoperative and intraoperative variables. When an invagination PJ leaks, there may be a greater influence on mortality than when a duct-to-mucosa PJ leaks

Rationale and design of ARTS: a randomized, double‐blind study of BAY 94‐8862 in patients with chronic heart failure and mild or moderate chronic kidney disease

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/106085/1/ejhfhfs061.pd