2 research outputs found
Stomatal Behavior of Arbuscular Mycorrhizal Plants
- Author
- 10.Atkinson C.J., Mansfield, T.A., McAinsh, M.R., Brownlee, C. and Hetherington
- 11.Augé R.M
- 14.Augé R.M., Duan, X., Ebel, R.C. and Stodola, A.J
- 15.Augé R.M., Schekel, K.A. and Wample, R.L
- 16.Augé R.M., Schekel, K.A. and Wample, R.L
- 17.Augé R.M., Schekel, K.A. and Wample, R.L
- 18.Augé R.M. and Stodola, J.W
- 19.Augé R.M., Stodola, A.J., Brown, M.S. and Bethlenfalvay, G.J
- 20.Augé R.M., Stodola, A.J., Ebel, R.C. and Duan
- 22.AzcĂłn R., Gomez, M. and Tobar
- 23.Baas R. and Kuiper, D
- 24.Bates L.M. and Hall, A.E
- 26.Bethlenfalvay G.J., Brown, M.S., and Franson
- 27.Bethlenfalvay G.J., Brown, M.S., Mihara, K. and Stafford
- 28.Bethlenfalvay G.J. and SchĂĽepp
- 44.Dakessian S., Brown, M.S. and Bethlenfalvay, G.J
- AAM Khalil
- AH Fitter
- AJ Jarvis
- AK Thakur
- Allen
- Bildusas I.J., Dixon, R.K., Pfleger, F.L. and Stewart, E.L
- Bradbury I.K. and Malcolm
- Brown D. and Rothery
- Bryla D.R. and Duniway
- Bryla D.R. and Duniway, J.M
- Burke J.J., Mahan, J.R. and Hatfield
- Busse M.D. and Ellis
- CD Green
- CE Nelsen
- CE Nelsen
- CE Nelsen
- CJ Atkinson
- Cornish K. and Zeevaart, J.A.D
- Cowan
- CP Andersen
- CP Reid
- CR Johnson
- CR Johnson
- D Atkinson
- Danneberg G., Latus, C., Zimmer, W., Hundeshagen, B., Schneider-Poetsch H.J. and Bothe, H
- Davies F.T. Jr., Castro-Jimenez, Y. and Duray, S.A
- Davies F.T., Potter, J.R. and Linderman, R.G
- Davies F.T., Potter, J.R. and Linderman, R.G
- Davies F.T., Svenson, S.E., Henderson, J.C., Phavaphutanon, L., Duray, S.A., OlaldePortugal, V., Meier, C.E. and Bo, S.H
- Davies W.J. and Zhang
- Davies W.J., Mansfield, T.A. and Hetherington, A.M
- Davies W.J., Tardieu, F. and Trejo, C.L
- De Silva. D.L.R. Cox, R.C., Hetherington, A.M. and Mansfield, T.A
- Desai M.C
- Di J.J. and Allen
- Dixon R.K., Garrett, H.E. and Cox, G.S
- Dixon R.K., Garrett, H.E. and Cox, G.S
- Dixon R.K., Rao, M.V. and Garg
- DJ Read
- DM Sylvia
- DP Wright
- Drtige U. and Schönbeck, F
- DS Neuman
- Duan X., Neuman, D S, Reiber, J.M., Green, C.D., Saxton, A.M. and Augé
- E Zeiger
- Eavis B.W., and Taylor
- EB Allen
- Ebel R.C., Duan, X., Still, D.W. and Augé, R.M
- Ebel R.C., Stodola, A.J.W., Duan, X. and Augé
- Ebel R.C., Welbaum, G.E., Gunatilaka, M., Nelson, T. and Augé
- Edriss M.H., Davis, R.M. and Burger
- Eissenstat D.M., Graham, J.H., Syvertsen, J.P. and Drouillard
- EL Greacen
- Esch H., Hundeshagen, B., Schneiderpoetsch, H. and Bothe, H
- F Meinzer
- F Tardieu
- F Tardieu
- Faber B.A., Zasoski, R.J., Munns, D.N. and Shackel
- Fahad A.A., Mielke, L.N., Flowerday, A.D. and Schwartzendruber
- Fay P., Mitchell, D.T. and Osborne, B.A
- FC Meinzer
- FE Sanders
- Field C.B
- Fitter
- Franson R.L, Milford, S.B and Bethlenfalvay
- FuĂźeder A., Wartinger, A., Hartung, W., Schulze, E.D. and Heilmeier, H
- Gemma J.N., Koske, R.E., Roberts, E.M., Jackson, N. and De Antonis, K
- George E., Haussler, K., Vetterlein, D., Gorgus, E. and Marschner
- GM Wang
- GR Safir
- H Meidner
- Hardie
- Hardie K
- Hartmond U., Schaesberg, N.V., Graham, J.H. and Syvertsen, J.P
- Hartung W. and Radin, J.W
- Hartung W., Radin, J.W. and Hendrix, D.L
- Hartung W., Wilkinson, S. and Davies
- Henderson J.C. and Davies, F.T
- HG Jones
- HG Jones
- HG Jones
- HG Reichenback
- Huang R.S., Smith, W.K. and Yost
- I Schwob
- I. Ginzberg
- I3.Augé R.M. and Duan, X
- Ibrahim M A, Campbell, W.F., Rupp, L.A. and Allen
- IE Okon
- Incoll L.D. and Jewer, P.C
- J Levitt
- J Ruiz-Lozano
- J Solarova
- J Zhang
- J Zhang
- J Zhang
- J Zhang
- J Zhang
- JD Trent
- JDB Weyers
- JH Graham
- JH Graham
- JH Graham
- JH Graham
- JH Graham
- JL Croker
- JM Oades
- JM Ruiz-Lozano
- JM Ruiz-Lozano
- JM Ruiz-Lozano
- Jones
- JP Syvertsen
- JR Ellis
- JR Mahan
- JW Radin
- JW Radin
- JW Radin
- JW Radin
- Koide
- Koide
- KS Subramanian
- KS Subramanian
- L Runjin
- L Schellenbaum
- LP Ruiz
- LR Cowan
- M Christensen
- M Christensen
- M Cui
- M Sanchez-Diaz
- MF Allen
- MF Allen
- MF Allen
- MF Allen
- MR McAinsh
- MR Sweatt
- MT Tyree
- N Goicoechea
- N Mathur
- NS Price
- NZ Saliendra
- O Osonubi
- O Osonubi
- Osundina
- PD Stahl
- PJ Kramer
- Pleasants
- R Koide
- RC Snellgrove
- RJ Jones
- RK Gupta
- RM Miller
- RT Koide
- S Nagarajah
- S Wilkinson
- SA Quarrie
- SC Wong
- SE Newman
- SE Newman
- SE Smith
- Sieverding
- Sieverding
- SK Kothari
- T Gollan
- TA Mansfield
- TA Mansfield
- Tisdall
- TR Thiagarajan
- U Schurr
- W Daeter
- W Jia
- Wright D.P., Scholes, J.D. and Read, D.J
- Y Levy
- Y Levy
- YH Shrestha
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2000
- Field of study
Resolved versus confirmed ARDS after 24 h: insights from the LUNG SAFE study
- Author
- Ñ
- Ü
- Abad R.D.
- Abe T.
- Abroug F.
- Adams J.C.
- Adamsson R.O.
- Adolfsson A.
- Aguilar R.Z.
- Aguirre J.S.
- Aguirre-Bermeo H.
- Aisa T.M.
- Aisiku I.
- Ajetunmobi O.O.
- Aker M.
- Akyol O.O.
- Albaiceta G.M.
- Albarrak M.M.
- Albiero D.
- Alda R.S.
- Alejandro R.V.
- Alexander P.
- Alfonso A.A.T.
- Algaba Á
- Aliaga F.A.
- Alisasis A.U.
- Allan R.M.
- Allue R.M.
- Almekhlafi G.
- Alonso J.G.
- Altaf W.
- Alvarez A.M.
- Alvarez J.
- Amin P.
- Amir F.
- Amor M.
- An Y.
- Andersen F.H.
- Andoh K.
- Andruszkiewicz P.
- Aneman A.
- Antô
- Antonelli M.M.
- Aoki N.
- Appelberg H.
- Arabi Y.
- Arabi Y.M.
- Araujo A.M.
- Arizmendi A.
- Arnal J.-M.
- Artiga M.J.D.
- Artigas A.
- Ascoli A.
- Au S.-M.
- Avila L.E.
- Azad R.
- Azevedo L.C.
- Bé
- Baboi L.
- Badie J.C.
- Bailey I.M.
- Bailey M.B.
- Bajwa E.
- Balkhi H.
- Baltus T.
- Banner-Goodspeed V.M.
- Barberet G.
- Baron R.M.
- Baronia A.K.
- Barratt-Due A.
- Barros F.M.
- Barros N.C.
- Batra H.
- Battle C.E.
- Bauer P.R.
- Beck E.
- Beck O.
- Bedreag O.H.
- Beegle S.H.
- Beitler J.R.
- Bellani G.
- Beloncle F.
- Benslama A.
- Beraldo D.O.
- Berghe C.
- Berkelmans F.
- Besset S.L.
- Bettini L.R.
- Beuret P.
- Bezzi M.G.
- Bhardwaj V.K.
- Bhowmick K.
- Biehler J.
- Bigot C.
- Bihari S.
- Biondi R.S.
- Biscione R.R.
- Bisso M.C.
- Black C.S.
- Blakeman T.C.
- Blanco J.
- Bolon S.
- Borello S.A.
- Borotto E.E.
- Bos L.D.
- Botteri M.
- Bouchoucha S.
- Boukhazna M.
- Bouw M.J.
- Boyd O.
- Bramall J.
- Braschi A.
- Brazzi L.
- Breen D.M.
- Briquet A.
- Brito V.A.
- Brizuela M.
- Brochard L.
- Broman L.M.
- Brown S.M.
- Browne T.S.
- Bruhn A.R.
- Brunettini B.
- Bruns M.M.
- Buensuseso J.A.
- Bugedo G.
- Buise M.P.
- Bulpa P.A.
- Bumbasierevic V.
- Bumbasirevic V.
- Burtenshaw A.J.
- Burtin P.
- Buzancais G.
- Camsooksai J.
- Canestrini S.
- Cani A.
- Carbayo-Gorriz C.
- Cardonnet L.P.
- Careless J.P.
- Carpentier D.
- Carreñ
- Carteaux G.
- Casalena P.
- Casement J.
- Castro A.G.
- Castro S.
- Catorze N.T.
- Cazorla-Barranquero F.G.
- Ceniceros-Barros A.
- Cereijo E.
- Cerny V.
- Cerrato V.I.
- Cervantes M.R.
- Cesar P.S.
- Ceunen H.
- Ceylan I.
- Chabanne R.
- Chapman R.
- Chau S.K.
- Chelly J.
- Chen K.
- Chena A.
- Cheng M.P.
- Chiche J.-D.
- Chouchene I.
- Choudry S.
- Christiansen A.
- Cimic N.
- Cinnella G.
- Cirone R.
- Citalá
- Claraco-Vega L.M.
- Clarkson K.
- Clarkson K.P.
- Claverias L.
- Cohen J.E.
- Cole J.M.
- Collins D.V.
- Collyer T.
- Colombo R.
- Combaux D.M.
- Combes A.
- Cooper R.
- Coppadoro A.
- Corneci D.E.
- Cortegiani A.
- Cortez C.A.
- Coxo C.M.
- Cracchiolo A.N.
- Cranshaw J.H.
- Crapelli G.
- Crouch D.R.
- Crouch D.R.
- Crova P.J.
- Csabi P.
- Curley G.
- Curto E.G.
- Dé
- Daldin J.
- Dangers L.
- Danin P.-E.
- Daubin C.
- Daviaud F.
- Davies K.G.
- Dawson H.
- De Cima-Iglesias S.
- De Haro C.
- de Prost N.
- De 
- De 
- Dean M.N.
- Declercq P.-L.M.
- Dector D.
- Dector D.M.
- Deicas A.
- del Carmen Lorente M.
- Dellamonica J.
- Dellera C.
- Delsing A.
- Demirkiran O.
- Demoule A.
- Dempsey G.
- Dendane T.
- Depuydt P.
- Depuydt P.
- Derman S.S.
- Di 
- Di Y.D.
- Diaz J.C.J.S.
- Diaz-Rodriguez E.
- Dive A.M.
- Dixit S.B.
- do Vale Fernandes A.
- Dolva M.S.
- Donnelly A.
- Dorzi H.M.A.
- Dowling A.T.
- Doyen D.
- Dres M.
- Dreyer K.R.
- Dreyer K.R.
- Dunne E.S.
- Dupont H.
- Duranteau J.
- Dwyer R.
- Ebeid A.
- Elatrous S.
- Elisabet G.M.
- Elkhayari M.
- Ellis H.E.
- Elmasri M.
- Erbabacan E.
- Eriksson K.E.
- Esteban A.
- Estenssoro E.
- Esteve F.
- Estilita J.M.
- Estrella C.R.
- Ezzouine H.
- Fan E.
- Fan E.
- Farí
- Fartoukh M.
- Fawkes D.A.
- Ferguson A.
- Ferguson N.D.
- Fernandez A.M.
- Fernandez R.O.
- Fierro J.M.
- Floris L.
- Fontenele D.C.
- Formenti P.
- Forteza C.
- Fossali T.
- Foti G.
- Franç
- Franco N.
- Frati E.
- Frendl G.
- Frigyik A.D.
- Fusari M.
- Futami S.
- Gó
- Gally J.
- Ganesan D.
- Gao Y.
- Gao Y.N.
- Garcia P.H.
- Gattinoni L.
- Gazenkampf A.A.
- Gelé
- George F.G.
- Ghazi M.
- Gianinetto H.
- Giarratano A.
- Gillis S.
- Girgin N.K.
- Gjedsted J.
- Glietsch R.
- Goldgran-Toledano D.
- Goligher E.C.
- Gomaa D.
- Gomaa D.
- Gomes R.M.
- Gomez P.E.
- Gomez-Flores S.S.
- Gonç
- Gonzá
- Gonzá
- Gonzalez D.R.
- Gonzalez M.
- Goodson J.C.
- Gordo F.
- Gosselin R.J.
- Goubaux B.
- Graziani R.
- Grelon F.
- Griffin R.O.
- Grigoriev E.
- Grijalba C.Q.
- Grissom C.K.
- Gritsan A.I.
- Grubissich N.
- Gué
- Gueret R.M.
- Gurjar M.
- Guttormsen A.B.
- Hacking D.J.
- Haddad Y.
- Hadfield D.
- Hagan S.J.
- Han H.
- Han Y.
- Hang A.Y.
- Hanlon G.C.
- Harasawa T.
- Harrois A.
- Hashemian S.M.
- Hashemian S.M.
- Hashida T.
- He Z.
- Hedlund L.
- Heidari F.
- Heines S.J.
- Helleberg J.
- Henderson G.
- Herbrecht J.-E.
- Hermosa C.
- Hessell R.J.
- Heunks L.M.
- Heunks L.M.
- Higashijima U.
- Hirata A.
- Holzgraefe B.
- Honda H.
- Honrubia T.
- Hopf H.-B.F.
- Hopkins P.
- Hormis A.P.
- Hou P.C.
- Hou S.-K.
- Hraiech S.
- Hua M.X.
- Huang Q.Q.
- Huang X.B.
- Huerta F.P.
- Huff N.G.
- Humphreys S.K.
- Hunt A.
- Hurtado J.
- Hurtado J.
- Hurtado J.
- Hutchison R.A.
- Hutton P.J.
- Ibañ
- Ichikado K.
- Ilutovich S.
- Imai H.
- Imma V.P.
- Imperio M.C.
- Inskip D.M.
- Ioannou N.
- Iotti G.A.
- Irvine D.A.
- Ismail D.
- Ismail D.M.A.B.P.H.
- Ismail M.
- Ito F.
- Izawa M.
- Jaafar R.F.
- Jabbary A.S.A.
- Jakubowska K.
- Jamaati H.
- Jarquin-Badiola Y.D.
- Jassal M.
- Javeed A.
- Jiang L.
- Jibaja M.
- Jimenez A.G.
- Jimenez J.I.S.
- Jochmans S.
- Jog S.A.
- Jovanovic B.
- Judy C.
- Jurado M.ª
- Kadaba V.
- Kajtor I.
- Kakar V.
- Kalaitzis E.
- Kalkoff M.
- Kamel G.
- Kameyama Y.
- Kamoun S.
- Kander T.
- Kannan S.G.
- Kashiwa Y.
- Kedelv H.
- Kennedy B.
- Khebbeb S.
- Kheir F.
- Kheir F.M.
- Kimura H.
- Kiourtzieva E.V.
- Kitch B.T.
- Knapman K.M.
- Knoll J.
- Knowles S.
- Kol M.R.
- Kong J.
- Koyama K.
- Kraß
- Krstevski A.
- Kulkarni S.
- Kumar A.
- Kurahashi K.
- Kusumoto K.
- Ló
- Laake J.H.
- Laake J.H.
- Labarca E.F.
- Laffey J.
- Laffey J.G.
- Lamb K.D.
- Lanspa M.J.
- Larsson A.
- Larsson A.
- Larsson N.
- Le 
- Lebbinck H.
- Lee J.
- Lee J.
- Lee J.
- Leemann-Refondini C.
- Lemiale V.
- Lemus J.S.
- Li B.
- Li Q.
- Li Q.J.
- Li W.
- Li X.
- Li X.L.
- Li Y.
- Li Y.Y.
- Li-Xin Z.
- Liew K.Y.
- Ling L.L.
- Liu H.
- Liu J.
- Liu J.L.
- Liu L.
- Llano M.
- Lohner R.
- Loiacono F.A.
- Lombardo A.
- Lopez E.B.
- Lopez-Delgado J.C.
- Lora F.S.
- Lora P.
- Lorente J.A.
- Losada E.P.
- Lovazzano P.
- Lu W.
- Lu Y.
- Luis P.S.E.
- LUNG SAFE Investigators and the ESICM Trials Group
- Luo X.
- Lynch J.M.
- Má
- Maazouzi W.
- Macfadyen R.
- MacFie C.C.
- Madotto F.
- Maeyama H.N.
- Maghrabi K.A.
- Magret M.
- Mahto H.L.
- Mancebo J.
- Manoharan V.
- Marcos D.P.
- Marcu A.
- Marin J.
- Marin M.C.
- Martinez F.T.
- Martinho A.M.
- Marum S.M.
- Massa E.V.
- Mataloun S.
- Matamis D.
- Matsumoto S.
- Mattei A.
- May M.M.
- Mcarthur C.
- McAuley D.
- McAuley D.F.
- McAuley D.F.
- McCalman K.H.
- McKechnie S.
- Mckee R.
- Mckenna T.E.
- Mcleod A.
- McNamee L.
- McNamee L.
- Meaney E.A.
- Meco B.C.
- Meersseman P.
- Mehta S.
- Mejia F.J.F.
- Mellis C.
- Memon M.
- Mercat A.
- Mesar T.
- Mesar T.
- Messias A.M.
- Messika J.
- Meybohm P.
- Michel P.
- Millar R.T.
- Miller J.J.
- Miller R.R.
- Mirabella L.
- Mizuguchi I.
- Mochizuki K.
- Mohr N.M.
- Mojoli F.
- Moles S.I.
- Molin A.
- Montanha G.M.
- Monteiro J.M.
- Montero L.A.
- Monti G.
- Montini L.M.
- Moock M.
- Morin A.-K.
- Mortaza S.
- Morton A.
- Mouloudi E.K.
- Moya D.D.L.
- Mukkera S.R.
- Mustafa G.M.
- Muthuchellappan R.
- Nagy E.O.
- Nakamura T.
- Namih M.
- Nassar A.P., Jr.
- Nasu M.
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- Neal J.
- Negoita S.L.
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- Nielsen J.
- Niimi D.
- Nin N.
- Nin N.
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- Nitta K.
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- Noremark K.A.L.
- Nuñ
- Nunci L.
- Nunes S.L.
- Nunomiya S.
- Nutt C.
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- O’
- O’
- O’
- O’
- Occhipinti G.
- Oetting T.W.
- Ogino Y.
- Oikonomou M.A.
- Okuda N.
- Oldroyd M.G.
- Olga M.F.
- Oliveira B.S.
- Ortiz C.A.
- Oscanoa F.A.M.
- Osman E.M.
- Oss P.
- Ouanes I.
- Ourailogloy V.
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- Palaniswamy V.
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- Palmese S.
- Palo J.E.
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- Papavasilopoulou T.G.
- Papazian L.
- Papurica M.
- Para L.H.
- Parhar K.
- Parotto M.
- Pasanting-Lim R.A.B.
- Patroniti N.
- Pattarino P.T.I.
- Pecci E.
- Pellegrini C.A.
- Pelletier N.
- Pellicer A.M.
- Penuelas O.
- Pereira C.S.
- Perez C.P.
- Perez M.P.
- Persson L.
- Pesenti A.
- Pham T.
- Pham T.
- Phan N.T.
- Piacentini E.A.
- Pillai S.
- Pintado M.C.
- Piquilloud L.
- Piquilloud L.
- Piras C.
- Pittini G.
- Plotnikow G.A.
- Poblano M.
- Poli M.M.
- Pota V.
- Pozo N.C.
- Pozzi M.
- Preez P.D.
- Prieto-Gonzá
- Pronovost A.
- Protti A.
- Qin B.
- Qin J.
- Qin S.H.
- Qin T.H.
- Qiu H.
- Qiu H.
- Raaijmakers M.
- Rafael S.I.
- Raimondi F.
- Raj A.S.
- Ramakrishnan N.
- Ramesh V.J.
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- Ranero J.L.
- Ranieri M.
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- Recio N.N.
- Reschreiter H.
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- Reuter D.
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- Rhayakar R.V.
- Rialp G.
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- Ricome S.
- Rigaud J.-P.
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- Rittayamai N.
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- Robine A.
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- Rojas M.A.G.
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- Sabelnikovs O.
- Sable S.D.
- Saenz M.G.
- Saez A.A.
- Sagar S.V.
- Saito K.
- Saito S.
- Salahuddin N.
- Salas J.E.
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- Sanchez R.J.
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- Sandesc D.
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- Sauvadet E.P.
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- Scafetti S.
- Schä
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- Schiavone V.
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- Schlichting A.B.
- Schneider F.
- Schomer A.
- Schouten J.A.
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- Seasman C.
- Seethala R.
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- Soler J.A.
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- Souissi A.B.
- Spadaro S.
- Srinivasa L.
- Stamou E.E.
- Staudinger T.
- Stephenson L.
- Stewart R.
- Stigler W.
- Strauch U.
- Strauch U.
- Sula H.
- Sun R.
- Surbatovic M.
- Suzuki H.
- Symmonds S.
- Szakmany T.
- Tabhan E.
- Tabhan E.E.
- Tainter C.
- Takaba A.
- Takada T.
- Takagi S.
- Tan B.C.
- Tanaka H.
- Tang R.
- Tapponnier R.
- Tarantino F.
- Temprano S.
- Terzi N.
- Thibault S.
- Thomas R.R.J.M.
- Thompson B.T.
- Thompson M.M.
- Tibblin A.O.
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- Tiribelli N.
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- Tomescu D.R.
- Toribio D.P.
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- Treanor N.
- Trinder T.J.
- Trinidad O.A.
- Tulaimat A.
- Twohey L.
- Uchiyama A.
- Ueda T.
- Ueno K.
- Umbrello M.
- Unnikrishnan R.
- Uppalapati A.
- van Haren F.
- Van Haren F.
- Van Wezel H.M.
- Vargas M.P.
- Vascotto E.R.
- Vasquez D.N.
- Vega L.D.
- Veljovic M.
- Venti A.
- Vercueil A.
- Vermassen J.
- Verstraete R.
- Villagomez A.
- Villagomez A.J.
- Villamagua B.G.
- Villar V.
- Vinzio M.
- Virgilio C.G.
- Vitale M.N.
- Volta C.A.
- Wang C.
- Wang H.X.
- Wang S.H.
- Wang W.
- Warren J.
- Watanabe E.
- Watt P.
- Welters I.D.
- Wenham T.
- Wessbergh J.
- Whitehead C.
- Willett E.L.
- Williams A.J.
- Williams K.E.
- Wise M.P.
- Wittebole X.
- Wong H.S.
- Woods P.W.
- Wrathall D.W.
- Wrigge H.
- Wrigge H.
- Wu Y.Q.
- Xin-Hua Q.
- Xu Y.
- Yamaguchi O.
- Yamaji Y.
- Yao Q.
- Ye Z.L.
- Yeatts D.J.
- Yoshido H.H.L.
- Yu R.
- Yu T.
- Yu W.
- Yumha J.S.
- Yuste L.J.
- Zacharas G.A.
- Zacharowski K.D.
- Zani G.
- Zantua K.S.
- Zazu A.
- Zeggwagh A.A.
- Zeggwagh A.A.
- Zein S.O.
- Zender H.O.
- Zhai Z.
- Zhang F.
- Zhang X.Y.
- Zhao H.
- Zhao J.
- Zhao X.Y.
- Zheng R.
- Zhou F.C.
- Zhou S.
- Zhu B.H.
- Zhu W.H.
- Zogheib E.H.
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2018
- Field of study
Purpose: To evaluate patients with resolved versus confirmed ARDS, identify subgroups with substantial mortality risk, and to determine the utility of day 2 ARDS reclassification. Methods: Our primary objective, in this secondary LUNG SAFE analysis, was to compare outcome in patients with resolved versus confirmed ARDS after 24\ua0h. Secondary objectives included identifying factors associated with ARDS persistence and mortality, and the utility of day 2 ARDS reclassification. Results: Of 2377 patients fulfilling the ARDS definition on the first day of ARDS (day 1) and receiving invasive mechanical ventilation, 503 (24%) no longer fulfilled the ARDS definition the next day, 52% of whom initially had moderate or severe ARDS. Higher tidal volume on day 1 of ARDS was associated with confirmed ARDS [OR 1.07 (CI 1.01\u20131.13), P = 0.035]. Hospital mortality was 38% overall, ranging from 31% in resolved ARDS to 41% in confirmed ARDS, and 57% in confirmed severe ARDS at day 2. In both\ua0resolved and confirmed\ua0ARDS, age, non-respiratory SOFA score, lower PEEP and P/F ratio, higher peak pressure and respiratory rate were each\ua0associated with mortality. In confirmed ARDS, pH and the presence of immunosuppression or neoplasm were also associated\ua0with mortality. The increase in area under the receiver operating curve for ARDS reclassification on day 2 was marginal. Conclusions: ARDS, whether resolved or confirmed at day 2, has a high mortality rate. ARDS reclassification at day 2 has limited predictive value for mortality. The substantial mortality risk in severe confirmed ARDS suggests that complex interventions might best be tested in this population. Trial Registration: ClinicalTrials.gov NCT02010073. \ua9 2018, Springer-Verlag GmbH Germany, part of Springer Nature and ESICM