92 research outputs found
Religious Meaning in T.S. Eliot\u27s Plays
Critics of Eliot often deal with his religious themes, but not with sympathy. In general, it seems that they are not at ease with Eliot\u27s religious views; so the tendency has been not to give them a careful, objective treatment. The purpose of my study of the plays is to attempt such an unbiased examination, to keep in view precisely what Eliot dues say and the religious meanings that are clearly implied. Whether Eliot\u27s ideas as they stand may be compatible or incompatible with the current thought climate is not, after all, the most important thing. He is a serious theological writer, sensitive and deep, and his plays deserve to be given a careful, straightforward reading, one that will make his major intentions clear. A number of critics, of course, do offer incisive comment on various matters, but a balanced, whole view of religious content in the\u27main plays seems to be needed. I have hoped at least to make a start toward such an important project
Beyond the Prediction Paradigm: Challenges for AI in the Struggle Against Organized Crime
In the future, audiological rehabilitation of adults with hearing loss will be more available, personalized and thorough due to the possibilities offered by the internet. By using the internet as a platform it is also possible to perform the process of rehabilitation in a cost-effective way. With tailored online rehabilitation programs containing topics such as communication strategies, hearing tactics and how to handle hearing aids it might be possible to foster behavioral changes that will positively affect hearing aid users. Four studies were carried out in this thesis. The first study investigated internet usage among adults with hearing loss. In the second study the administration format, online vs. paper- and pencil, of four standardized questionnaires was evaluated. Finally two randomized controlled trials were performed evaluating the efficacy of online rehabilitation programs including professional guidance by an audiologist. The programs lasted over five weeks and were designed for experienced adult hearing-aid users. The effects of the online programs were compared with the effects of a control group. It can be concluded that the use of computers and the internet overall is at least at the same level for people with hearing loss as for the general age-matched population in Sweden. Furthermore, for three of the four included questionnaires, the participantsâ scores remained the same across formats. It is however recommended that the administration format remain consistent across assessment points. Finally, results from the two concluding intervention studies provide preliminary evidence that the internet can be used to deliver education and rehabilitation to experienced hearing aid users who report residual hearing problems and that their problems are reduced by the intervention; however the content and design of the online rehabilitation program requires further investigation
Generating Reality, Silencing Debate: Synthetic Data as Discursive Device
In addition to tapping data from usersâ behavioral surplus, by drawing on generative adversarial networks, data for artificial intelligence is now increasingly being generated through artificial intelligence. With this new method of producing data synthetically, the data economy is not only shifting from âdata collectionâ to âdata generation.â Synthetic data is also being employed to address some of the most pressing ethical concerns around artificial intelligence. It thereby comes with the sociotechnical imaginary that social problems can be cut out of artificial intelligence, separating training data from real persons. In response to this technical solutionism, this commentary aims to initiate a critical debate about synthetic data that goes beyond misuse scenarios such as the use of generative adversarial networks to create deep fakes or dark patterns. Instead, on a more general level, we seek to complicate the idea of âsolving,â i.e., âclosingâ and thus âsilencingâ the ethico-political debates for which synthetic data is supposed to be a solution by showing how synthetic data itself is political. Drawing on the complex connections between recent uses of synthetic data and public debates about artificial intelligence, we therefore propose to consider and analyze synthetic data not only as a technical device but as a discursive one as well. To this end, we shed light on their relationship to three pillars that we see associated with them (a) algorithmic bias, (b) privacy, (c) platform economy
Layers of technology in pluriversal design. Decolonising language technology with the LiveLanguage initiative
Language technology has the potential to facilitate intercultural
communication through meaningful translations. However, the current state of
language technology is deeply entangled with colonial knowledge due to path
dependencies and neo-colonial tendencies in the global governance of artificial
intelligence (AI). Language technology is a complex and emerging field that
presents challenges for co-design interventions due to enfolding in assemblages
of global scale and diverse sites and its knowledge intensity. This paper uses
LiveLanguage, a lexical database, a set of services with particular emphasis on
modelling language diversity and integrating small and minority languages, as
an example to discuss and close the gap from pluriversal design theory to
practice. By diversifying the concept of emerging technology, we can better
approach language technology in global contexts. The paper presents a model
comprising of five layers of technological activity. Each layer consists of
specific practices and stakeholders, thus provides distinctive spaces for
co-design interventions as mode of inquiry for de-linking, re-thinking and
re-building language technology towards pluriversality. In that way, the paper
contributes to reflecting the position of co-design in decolonising emergent
technologies, and to integrating complex theoretical knowledge towards
decoloniality into language technology design
ExperiĂȘncias e conhecimentos produzidos na luta social : "Una historia que tiene que ver con el curso de la VĂa LĂĄctea"
Desde a ascensĂŁo do sistema capitalista a sociedade vem sendo condenada a modelos de desenvolvimento e estilos de vida caracterizados pelo aumento da produtividade e maximização do lucro, tornando-se insustentĂĄvel e exigindo mudanças profundas na sua estrutura. Tais mudanças exigem uma desconstrução dos valores sociais e uma ruptura do modelo econĂŽmico vigente para que seja possĂvel a construção de uma nova concepção de desenvolvimento, que resulte em uma sociedade social e ecologicamente justa, igualitĂĄria e que seja ela prĂłpria sujeita de seu prĂłprio destino. O Movimento dos Trabalhadores Rurais Sem Terra propĂ”em uma educação que se contrapĂ”em ao modelo clĂĄssico de ensino que reflete e reforça as estruturas e as relaçÔes desiguais da sociedade alĂ©m da cultura que as legitima. Estudar o MST como sujeito educativo polĂtico e suas prĂĄticas pedagĂłgicas, dentro e fora da escola, Ă© uma forma de compreender como a cultura, como modo de vida, do Movimento pode servir de exemplo na concepção de uma nova sociedade mais humana e justa
PEGylated DOTA-AHA-based Gd(III) chelates â A relaxometric study
Three PEGylated derivatives of 1,4,7,10-tetraazacyclododecane-1-((6-amino)hexanoic)-4,7,10-triacetic acid) (DOTA-AHA) with different molecular weights were prepared and characterized. Their Gd(III) chelates were studied in aqueous solution using variable-temperature 1H nuclear magnetic relaxation dispersion (NMRD) and 17ONMR spectroscopy in view of the determination of their relaxivity and the parameters that govern it. The relaxivity varied from 5.1 to 6.5 mM-1.s-1 (37 ÂșC and 60 MHz) with the increasing molecular weight of the PEG chain, being slightly higher than that of the parent chelate Gd(DOTA-AHA), due to a small contribution of a slow global rotation of the complexes.
A variable temperature 1H NMR study of several Ln(III) chelates of DOTA-A(PEG750)HA allowed the determination of the isomeric M/m ratio (M = square antiprismatic isomer and m = twisted square antiprismatic isomer, the latter presenting a much faster water exchange) which for the Gd(III) chelate was estimated in circa 1:0.2, very close to that of [Gd(DOTA)]-. This explains why the PEGylated Gd(III) chelate has a water rate exchange similar to that of [Gd(DOTA)]-. The predominance of the M isomer is a consequence of the bulky PEG moiety which does not favor the stabilization of the m isomer in sterically crowded systems at the substituent site, contrary to what happens with less packed asymmetrical DOTA-type chelates with substitution in one of the four acetate C(α) atoms.The authors thank the Foundation for Science and Technology (FCTâPortugal) for financial support through the NMR Portuguese network (Bruker 400 Avance III-Univ Minho); FCT and FEDER (European Fund for Regional Development)-COMPETE/QREN/EU for financial support through the research unity PEst-C/QUI/UI686/2013 and the PhD grant attributed to AndrĂ© Fontes (SFRH/BD/63676/2009) also financed by the POPH and FSE
Binuclear DOTA-based Gd(III) chelates: revisiting a straightforward strategy for relaxivity improvement
The need for MRI contrast agents with improved relaxivity maintains the development of new Gd(III) chelates an intensive and demanding field of research. In this work we introduce the new dimeric chelators bis(DOTA-AHA)adipate and bis(DOTA-AHA)1,3-phenyldiacetate (L2 = bis(1,4,7,10-tetraazacyclododecane-1-((6-amino)hexanoic)-4,7,10-triacetic acid)adipate and L3 = bis(1,4,7,10-tetraazacyclododecane-1-((6-amino)hexanoic)-4,7,10-triacetic acid)1,3-phenyldiacetate, respectively), based on the bifunctional ligand DOTA-AHA (L1 = 1,4,7,10-tetraazacyclododecane-1-((6-amino)hexanoic)-4,7,10-triacetic acid). Their Gd(III) chelates were studied by variable temperature 1H NMRD and 17O NMR spectroscopy in order to measure the relaxivity and the parameters that govern it. The exchange of inner-sphere water from the monomer GdL1 and from the two binuclear chelates Gd2L2 and Gd2L3 is very similar (298kex â 6.5 x106 s-1) and slightly faster than on [Gd(DOTA)H2O]- (298kex = 4.1 x 106 s-1). All three compounds form weakly bound aggregates with equilibrium constants 298K of 2.9, 15.6 and 14.6 for GdL1, Gd2L2 and Gd2L3, respectively. Even if the aggregates contain only 10 to 15% of the total amount of Gd(III) ions a marked increase in relaxivity between 30 and 100 MHz is observed.
Furthermore the distance between the two Gd(III) centers in the binuclear compounds has been determined by double electron-electron resonance (DEER) experiments and by molecular modelling studies affording comparable distances. The linkers between the chelating moieties allow Gd(III)-Gd(III) distances of circa 3.0 nm for completely stretched linker conformation and †1.9 nm for the conformation with the metal centers at closer distance. These metal to metal distances by themselves cannot explain the considerably long tumbling times of chelates in solution. Only a model consistent with some level of aggregation for the binuclear chelates in aqueous solution could satisfactorily explain our results.The authors thank the Foundation for Science and Technology (FCTâPortugal) for
financial support through the NMR Portuguese network (Bruker 400 Avance III-Univ
Minho); FCT and FEDER (European Fund for Regional Development)-
COMPETE/QREN/EU for financial support through the research unity PEstC/QUI/UI686/2013
and the PhD grant attributed to André Fontes
(SFRH/BD/63676/2009) also financed by the POPH and FSE. SK and LH thank the
Swiss National Science Foundation for financial support.info:eu-repo/semantics/publishedVersio
Diversity and Neocolonialism in Big Data Research. Avoiding extractivism while struggling with paternalism.
The extractive logic of Big Data-driven technology and knowledge production has raised serious concerns. While most criticism initially focused on the impacts on Western societies, attention is now increasingly turning to the consequences for communities in the Global South. To date, debates have focused on private-sector activities. In this article, we start from the conviction that publicly funded knowledge and technology production must also be scrutinized for their potential neocolonial entanglements. To this end, we analyze the dynamics of collaboration in an European Union-funded research project that collects data for developing a social platform focused on diversity. The project includes pilot sites in China, Denmark, the United Kingdom, India, Italy, Mexico, Mongolia, and Paraguay. We present the experience at four field sites and reflect on the projectâs initial conception, our collaboration, challenges, progress, and results. We then analyze the different experiences in comparison. We conclude that while we have succeeded in finding viable strategies to avoid contributing to the dynamics of unilateral data extraction as one side of the neocolonial circle, it has been infinitely more difficult to break through the much more subtle but no less powerful mechanisms of paternalism that we find to be prevalent in data-driven NorthâSouth relations. These mechanisms, however, can be identified as the other side of the neocolonial circle.</p
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