2,214 research outputs found

    Object-based learning in higher education: The pedagogical power of museums

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    Following a special conference focused on object-based learning in higher education at University College London (UCL), this paper provides the overview for a series of subsequent papers which explore the value of object-based learning, including the pedagogical framework for museum learning in the university classroom and practice led examples from a range of disciplines. Object-based learning in higher education draws on many of the learning strategies already known to inform students, including active learning and experiential learning; this collection of papers draws together examples of object-based learning pioneered at UCL and seeks to encourage enhanced use of university collections in new, pedagogically powerful, modes

    Estimating the phylogeny and divergence times of primates using a supermatrix approach

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    <p>Abstract</p> <p>Background</p> <p>The primates are among the most broadly studied mammalian orders, with the published literature containing extensive analyses of their behavior, physiology, genetics and ecology. The importance of this group in medical and biological research is well appreciated, and explains the numerous molecular phylogenies that have been proposed for most primate families and genera. Composite estimates for the entire order have been infrequently attempted, with the last phylogenetic reconstruction spanning the full range of primate evolutionary relationships having been conducted over a decade ago.</p> <p>Results</p> <p>To estimate the structure and tempo of primate evolutionary history, we employed Bayesian phylogenetic methods to analyze data supermatrices comprising 7 mitochondrial genes (6,138 nucleotides) from 219 species across 67 genera and 3 nuclear genes (2,157 nucleotides) from 26 genera. Many taxa were only partially represented, with an average of 3.95 and 5.43 mitochondrial genes per species and per genus, respectively, and 2.23 nuclear genes per genus. Our analyses of mitochondrial DNA place Tarsiiformes as the sister group of Strepsirrhini. Within Haplorrhini, we find support for the primary divergence of Pitheciidae in Platyrrhini, and our results suggest a sister grouping of African and non-African colobines within Colobinae and of Cercopithecini and Papionini within Cercopthecinae. Date estimates for nodes within each family and genus are presented, with estimates for key splits including: Strepsirrhini-Haplorrhini 64 million years ago (MYA), Lemuriformes-Lorisiformes 52 MYA, Platyrrhini-Catarrhini 43 MYA and Cercopithecoidea-Hominoidea 29 MYA.</p> <p>Conclusion</p> <p>We present an up-to-date, comprehensive estimate of the structure and tempo of primate evolutionary history. Although considerable gaps remain in our knowledge of the primate phylogeny, increased data sampling, particularly from nuclear loci, will be able to provide further resolution.</p

    Volunteering for Wellbeing: Improving Access and Social Inclusion by Increasing the Diversity of Museum Volunteer Training for Public-facing Roles

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    This article reports outcomes from a 15-month (2018-19) study led by UCL on behalf of the Culture, Health and Wellbeing Alliance in partnership with three London museums of differing sizes with natural or local history collections. The study aimed to address mental health inequalities by diversifying volunteer populations through reforming recruitment procedures to overcome perceived barriers, and enriching training programmes to improve wellbeing. A mixed methods approach was used to assess wellbeing and mechanisms by which key benefits were derived, such as social interaction and forming connections. The article considers how increasing the diversity of volunteer training in museums can improve wellbeing, widen access and promote social inclusion. Policy and practice implications are discussed in relation to embedding wellbeing training strategies into heritage organizations

    The role of museums, collections, and objects in supporting higher education student mental well-being and quality of learning

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    This chapter focuses on the potential role of museums and cultural collections in facilitating student well-being. In order to investigate the potential relationship between object engagement and student well-being, several groups of students undertaking modules that involved engaging with museum objects were asked to participate in an anonymous online survey. The UCL students who participated in the survey seemed to recognise the need to cope more effectively with stress manifested in the fact that over three-quarters of respondents thought that well-being activities should be incorporated into taught modules, with 30% of them proposing extra curricula relaxation techniques such as yoga, meditation, and mindfulness. Workshops and visits also enhance student engagement and interest, though to a slightly lesser extent than that of well-being. The fact that object-based learning activities, especially when performed outside the regular classroom environment, such as in a museum or collection space, appear to meet the expressed needs of the students is encouraging

    Museopathy: Exploring the Healing Potential of Handling Museum Objects

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    To coincide with emerging arts and health practices, University College London Museums Collections and University College London Hospitals Arts partnered to create a pilot project, entitled “Heritage in Hospitals”, which sought to assess whether handling museum objects has a positive impact on patient wellbeing. Quantitative data from 32 sessions conducted with patients in May through July (inclusive) of 2008 demonstrated, on average, an increase in self-reported measures of life satisfaction and health status after handling museum objects. Constant comparative analysis of the qualitative data collected from the sessions revealed two major recurring themes: “impersonal/educational” and “personal/reminiscence”. The first theme included instances where handling museum objects allowed patients to access truths about the objects ascertainable solely through touch (such as gauging weight, texture, temperature, and spatial relation to the body), to verify what was seen, to facilitate an intimate and imaginative connection with the museum objects and their origins, to investigate and explore the objects, to permit an interaction with the “rare” and “museum-worthy”, and to assist with aesthetic appreciation. The second theme illustrated the project’s potential to assist with counselling on issues of illness, death, loss and mourning, and to help restore dignity, respect and a sense of identity (particularly among elderly patients) by providing a springboard for reminiscing and the telling of life stories in a highly institutionalized setting. This paper contextualizes the project, explores the implications of the project’s methodology and its findings, and provides questions for future research

    The Impact of Culture-, Health- and Nature-Based Engagement on Mitigating the Adverse Effects of Public Health Restrictions on Wellbeing, Social Connectedness and Loneliness during COVID-19: Quantitative Evidence from a Smaller- and Larger-Scale UK Survey

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    Numerous UK surveys conducted during COVID-19 examined the pandemic’s detrimental effects on health, and the consequences of lockdown and other public health restrictions on mental health. Some surveys considered specific populations and social inequities exacerbated during COVID-19. Fewer surveys examined the ways in which the adverse effects of public health restrictions, such as lockdown, shielding and social distancing, might be alleviated. Drawing upon self-determination theory, the purpose of the current study was to assess whether culture-, health- and nature-based engagement would mitigate the effects of these restrictions on psychological wellbeing, social connectedness and loneliness. Quantitative data from a smaller-scale survey (n = 312) and a subset of questions embedded in a larger-scale survey (n = 3647) were analyzed using univariate and multivariate methods. Frequency of engagement, whether participation was online or offline and with or without other people, and the extent to which type of participation was associated with psychological wellbeing, social connectedness and loneliness were examined. Sports and fitness, gardening and reading occurred frequently in both surveys. For the smaller-scale survey, increases in connectedness and frequency of participation and decreases in loneliness were significantly associated with improved wellbeing, whereas the type of participation and age range were not significant predictors. Outcomes from the smaller-scale survey approximated the larger-scale survey for measures of loneliness, type and frequency of participation and proportion of respondents in each age range. As the frequency of participation was a significant predictor of wellbeing, but the type of participation was not significant, the findings implied that any type of participation in a sufficient quantity would be likely to boost wellbeing

    Assessing the impact of artistic and cultural activities on the health and well-being of forcibly displaced people using participatory action research

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    Objective Drawing on a growing body of research suggesting that taking part in artistic and cultural activities benefits health and well-being, the objective was to develop a participatory action research (PAR) method for assessing the impact of arts interventions on forcibly displaced people, and identify themes concerning perceived benefits of such programmes. Design A collaborative study following PAR principles of observation, focus groups and in-depth semistructured interviews. Setting London-based charity working with asylum seekers and refugees. Participants An opportunity sample (n=31; 6 males) participated in focus groups comprising refugees/asylum seekers (n=12; 2 males), volunteers (n=4; 1 males) and charity staff (n=15; 3 males). A subset of these (n=17; 3 males) participated in interviews comprising refugees/asylum seekers (n=7; 1 males), volunteers (n=7; 1 males) and charity staff (n=3; 1 males). Results Focus group findings showed that participants articulated the impact of creative activities around three main themes: skills, social engagement and personalemotions that were explored during in-depth interviews. Thematic analysis of interviews was conducted in NVivo 11 and findings showed that artistic and cultural activities impacted positively by helping participants find a voice, create support networks and learn practical skills useful in the labour market. Conclusions The study expanded on arts and well-being research by exploring effects of cultural and creative activities on the psychosocial well-being of refugees and asylum seekers. By focusing on the relationship between arts, well-being and forced displacement, the study was instrumental in actively trying to change the narrative surrounding refugees and asylum seekers, often depicted in negative terms in the public sphere

    Targeted exome sequencing integrated with clinicopathological information reveals novel and rare mutations in atypical, suspected and unknown cases of Alport syndrome or proteinuria

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    We applied customized targeted next-generation exome sequencing (NGS) to determine if mutations in genes associated with renal malformations, Alport syndrome (AS) or nephrotic syndrome are a potential cause of renal abnormalities in patients with equivocal or atypical presentation. We first sequenced 4,041 exons representing 292 kidney disease genes in a Caucasian woman with a history of congenital vesicoureteral reflux (VUR), recurrent urinary tract infections and hydronephrosis who presented with nephrotic range proteinuria at the age of 45. Her biopsy was remarkable for focal segmental glomerulosclerosis (FSGS), a potential complication of longstanding VUR. She had no family history of renal disease. Her proteinuria improved initially, however, several years later she presented with worsening proteinuria and microhematuria. NGS analysis revealed two deleterious COL4A3 mutations, one novel and the other previously reported in AS, and a novel deleterious SALL2 mutation, a gene linked to renal malformations. Pedigree analysis confirmed that COL4A3 mutations were nonallelic and compound heterozygous. The genomic results in conjunction with subsequent abnormal electron microscopy, Collagen IV minor chain immunohistochemistry and progressive sensorineural hearing loss confirmed AS. We then modified our NGS approach to enable more efficient discovery of variants associated with AS or a subset of FSGS by multiplexing targeted exome sequencing of 19 genes associated with AS or FSGS in 14 patients. Using this approach, we found novel or known COL4A3 or COL4A5 mutations in a subset of patients with clinically diagnosed or suspected AS, APOL1 variants associated with FSGS in African Americans and novel mutations in genes associated with nephrotic syndrome. These studies demonstrate the successful application of targeted capture-based exome sequencing to simultaneously evaluate genetic variations in many genes in patients with complex renal phenotypes and provide insights into etiology of conditions with equivocal clinical and pathologic presentations

    Lay health worker led intervention for depressive and anxiety disorders in India: impact on clinical and disability outcomes over 12 months.

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    BACKGROUND: Depressive and anxiety disorders (common mental disorders) are the most common psychiatric condition encountered in primary healthcare. AIMS: To test the effectiveness of an intervention led by lay health counsellors in primary care settings (the MANAS intervention) to improve the outcomes of people with common mental disorders. METHOD: Twenty-four primary care facilities (12 public, 12 private) in Goa (India) were randomised to provide either collaborative stepped care or enhanced usual care to adults who screened positive for common mental disorders. Participants were assessed at 2, 6 and 12 months for presence of ICD-10 common mental disorders, the severity of symptoms of depression and anxiety, suicidal behaviour and disability levels. All analyses were intention to treat and carried out separately for private and public facilities and adjusted for the design. The trial has been registered with clinical trials.gov (NCT00446407). RESULTS: A total of 2796 participants were recruited. In public facilities, the intervention was consistently associated with strong beneficial effects over the 12 months on all outcomes. There was a 30% decrease in the prevalence of common mental disorders among those with baseline ICD-10 diagnoses (risk ratio (RR) = 0.70, 95% CI 0.53-0.92); and a similar effect among the subgroup of participants with depression (RR = 0.76, 95% CI 0.59-0.98). Suicide attempts/plans showed a 36% reduction over 12 months (RR=0.64, 95% CI0.42–0.98) among baseline ICD-10 cases. Strong effects were observed on days out of work and psychological morbidity, and modest effects on overall disability [corrected]. In contrast, there was little evidence of impact of the intervention on any outcome among participants attending private facilities. CONCLUSIONS: Trained lay counsellors working within a collaborative-care model can reduce prevalence of common mental disorders, suicidal behaviour, psychological morbidity and disability days among those attending public primary care facilities

    Effects of a museum-based social-prescription intervention on quantitative measures of psychological wellbeing in older adults

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    Aims: To assess psychological wellbeing in a novel social prescription intervention for older adults called Museums on Prescription, and to explore the extent of change over time in six self-rated emotions (‘absorbed, ‘active’, ‘cheerful’, ‘encouraged’, ‘enlightened’ and ‘inspired’). Methods: Participants (n=115) aged 65-94 were referred to museum-based programmes comprising 10, weekly sessions, by healthcare and third sector organisations using inclusion criteria (e.g. socially isolated; able to give informed consent; not in employment; not regularly attending social or cultural activities) and exclusion criteria (e.g. unable to travel to the museum; unable to function in a group situation; unlikely to be able to attend all sessions; unable to take part in interviews and complete questionnaires). In a within-participants design, the Museum Wellbeing Measure for Older Adults (MWM-OA) was administered pre-post session at start- mid- and end-programme. Twelve programmes, facilitated by museum staff and volunteers, were conducted in seven museums in central London and across Kent. In addition to the quantitative measures, participants, carers where present, museum staff and researchers kept weekly diaries following guideline questions, and took part in end programme in-depth interviews. Results: Multivariate analyses of variance showed significant participant improvements in all six MWM-OA emotions, pre-post session at start- mid- and end-programme. Two emotions, ‘absorbed’ and ‘enlightened’, increased pre-post session disproportionately to the others; ‘cheerful’ attained the highest pre-post session scores whereas ‘active’ was consistently lowest. Conclusions: Museums can be instrumental in offering museum-based programmes for older adults to improve psychological wellbeing over time. Participants in the study experienced a sense of privilege, valued the opportunity to liaise with curators, visit parts of the museum closed to the public, and handle objects normally behind glass. Participants appreciated opportunities afforded by creative and co-productive activities to acquire learning and skills, and get to know new people in a different context
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