19 research outputs found
The VLBA Imaging and Polarimetry Survey at 5 GHz
We present the first results of the VLBA Imaging and Polarimetry Survey
(VIPS), a 5 GHz VLBI survey of 1,127 sources with flat radio spectra. Through
automated data reduction and imaging routines, we have produced publicly
available I, Q, and U images and have detected polarized flux density from 37%
of the sources. We have also developed an algorithm to use each source's I
image to automatically classify it as a point-like source, a core-jet, a
compact symmetric object (CSO) candidate, or a complex source. The mean ratio
of the polarized to total 5 GHz flux density for VIPS sources with detected
polarized flux density ranges from 1% to 20% with a median value of about 5%.
We have also found significant evidence that the directions of the jets in
core-jet systems tend to be perpendicular to the electric vector position
angles (EVPAs). The data is consistent with a scenario in which ~24% of the
polarized core-jets have EVPAs that are anti-aligned with the directions of
their jet components and which have a substantial amount of Faraday rotation.
In addition to these initial results, plans for future follow-up observations
are discussed.Comment: 36 pages, 3 tables, 13 figures; accepted for publication in Ap
Design and construction of the MicroBooNE detector
This paper describes the design and construction of the MicroBooNE liquid
argon time projection chamber and associated systems. MicroBooNE is the first
phase of the Short Baseline Neutrino program, located at Fermilab, and will
utilize the capabilities of liquid argon detectors to examine a rich assortment
of physics topics. In this document details of design specifications, assembly
procedures, and acceptance tests are reported
Genome-Wide Association Study in BRCA1 Mutation Carriers Identifies Novel Loci Associated with Breast and Ovarian Cancer Risk
BRCA1-associated breast and ovarian cancer risks can be modified by common genetic variants. To identify further cancer risk-modifying loci, we performed a multi-stage GWAS of 11,705 BRCA1 carriers (of whom 5,920 were diagnosed with breast and 1,839 were diagnosed with ovarian cancer), with a further replication in an additional sample of 2,646 BRCA1 carriers. We identified a novel breast cancer risk modifier locus at 1q32 for BRCA1 carriers (rs2290854, P = 2.7Ă—10-8, HR = 1.14, 95% CI: 1.09-1.20). In addition, we identified two novel ovarian cancer risk modifier loci: 17q21.31 (rs17631303, P = 1.4Ă—10-8, HR = 1.27, 95% CI: 1.17-1.38) and 4q32.3 (rs4691139, P = 3.4Ă—10-8, HR = 1.20, 95% CI: 1.17-1.38). The 4q32.3 locus was not associated with ovarian cancer risk in the general population or BRCA2 carriers, suggesting a BRCA1-specific associat