An Enhanced Default Approach Bias Following Amygdala Lesions in Humans

Approach and avoidance constitute a basic dimension of all animal behavior. Although a large number of studies have investigated approach and avoidance elicited by specific sensory stimuli, comparatively little is known about default approach biases when stimulus information is absent or reduced. The amygdala is well known to contribute to approach and avoidance behaviors in response to specific sensory stimuli; we tested whether the amygdala’s role might extend to situations in which stimulus information is reduced. In a novel task, 3 patients with rare bilateral amygdala lesions (and control subjects) made approach-related judgments about photos of intact faces and of the same faces with all internal facial features occluded. Direct comparisons of the judgments of these stimuli isolated a default bias. The patients showed a greater tendency than the control subjects to rate occluded faces as more approachable than whole faces. These findings suggest that the amygdala’s role in approach behavior extends beyond responses to specific stimuli

Exploring the Structure of Human Defensive Responses from Judgments of Threat Scenarios

How humans react to threats is a topic of broad theoretical importance, and also relevant for understanding anxiety disorders. Many animal threat reactions exhibit a common structure, a finding supported by human evaluations of written threat scenarios that parallel patterns of rodent defensive behavior to actual threats. Yet the factors that underlie these shared behavioral patterns remain unclear. Dimensional accounts rooted in Darwin’s conception of antithesis explain many defensive behaviors. Across species, it is also clear that defensive reactions depend on specific situational factors, a feature long emphasized by psychological appraisal theories. Our study sought to extend prior investigations of human judgments of threat to a broader set of threats, including natural disasters, threats from animals, and psychological (as opposed to physical) threats. Our goal was to test whether dimensional and specific patterns of threat evaluation replicate across different threat classes. 85 healthy adult subjects selected descriptions of defensive behaviors that indicated how they would react to 29 threatening scenarios. Scenarios differed with respect to ten factors, e.g., perceived dangerousness or escapability. Across scenarios, we correlated these factor ratings with the pattern of defensive behaviors subjects endorsed. A decision tree hierarchically organized these correlation patterns to successfully predict each scenario’s most common reaction, both for the original sample of subjects and a separate replication group (n = 22). At the top of the decision tree, degree of dangerousness interacted with threat type (physical or psychological) to predict dimensional approach/avoidance behavior. Subordinate nodes represented specific defensive responses evoked by particular contexts. Our ecological approach emphasizes the interplay of situational factors in evoking a broad range of threat reactions. Future studies could test predictions made by our results to help understand pathological threat processing, such as seen in anxiety disorders, and could begin to test underlying neural mechanisms

The Importance of Sensory Processing in Mental Health: A Proposed Addition to the Research Domain Criteria (RDoC) and Suggestions for RDoC 2.0

The time is ripe to integrate burgeoning evidence of the important role of sensory and motor functioning in mental health within the National Institute of Mental Health’s [NIMH] Research Domain Criteria [RDoC] framework (National Institute of Mental Health, n.d.a), a multi-dimensional method of characterizing mental functioning in health and disease across all neurobiological levels of analysis ranging from genetic to behavioral. As the importance of motor processing in psychopathology has been recognized (Bernard and Mittal, 2015; Garvey and Cuthbert, 2017; National Institute of Mental Health, 2019), here we focus on sensory processing. First, we review the current design of the RDoC matrix, noting sensory features missing despite their prevalence in multiple mental illnesses. We identify two missing classes of sensory symptoms that we widely define as (1) sensory processing, including sensory sensitivity and active sensing, and (2) domains of perceptual signaling, including interoception and proprioception, which are currently absent or underdeveloped in the perception construct of the cognitive systems domain. Then, we describe the neurobiological basis of these psychological constructs and examine why these sensory features are important for understanding psychopathology. Where appropriate, we examine links between sensory processing and the domains currently included in the RDoC matrix. Throughout, we emphasize how the addition of these sensory features to the RDoC matrix is important for understanding a range of mental health disorders. We conclude with the suggestion that a separate sensation and perception domain can enhance the current RDoC framework, while discussing what we see as important principles and promising directions for the future development and use of the RDoC

A Spatially Resolved Study of the Synchrotron Emission and Titanium in Tycho's Supernova Remnant with NuSTAR

We report results from deep observations (~750 ks) of Tycho's supernova remnant (SNR) with NuSTAR. Using these data, we produce narrow-band images over several energy bands to identify the regions producing the hardest X-rays and to search for radioactive decay line emission from 44Ti. We find that the hardest (>10 keV) X-rays are concentrated in the southwest of Tycho, where recent Chandra observations have revealed high emissivity "stripes" associated with particles accelerated to the knee of the cosmic-ray spectrum. We do not find evidence of 44Ti, and we set limits on its presence and distribution within the SNR. These limits correspond to a upper-limit 44Ti mass of M44 < 2.4x10^-4 M_sun for a distance of 2.3 kpc. We perform spatially resolved spectroscopic analysis of sixty-six regions across Tycho. We map the best-fit rolloff frequency of the hard X-ray spectra, and we compare these results to measurements of the shock expansion and ambient density. We find that the highest energy electrons are accelerated at the lowest densities and in the fastest shocks, with a steep dependence of the roll-off frequency with shock velocity. Such a dependence is predicted by models where the maximum energy of accelerated electrons is limited by the age of the SNR rather than by synchrotron losses, but this scenario requires far lower magnetic field strengths than those derived from observations in Tycho. One way to reconcile these discrepant findings is through shock obliquity effects, and future observational work is necessary to explore the role of obliquity in the particle acceleration process.Comment: 12 pages, 12 figures, ApJ in pres

Exploring operational ecosystem service definitions : the case of boreal forests

Highlights • We examine alternative ways of defining and classifying ecosystem services by using an example of a boreal forest in Finland. • We suggest using the notion of final ecosystem goods and services in economic valuation and other priority setting contexts. • In the context of awareness raising it might be more effective to retain the well-established terminology of the M A. • We find a definition of ecosystem services value, which is based on willingness to pay, too narrow. • We suggest regarding both natural and semi-natural ecosystem outputs as ecosystem services.Despite the widespread use of the concept of ecosystem services, there is still much uncertainty over the precise understanding of basic terms such as 'ecosystem services', 'benefits' and 'values'. This paper examines alternative ways of defining and classifying ecosystem services by using the specific example of boreal forests in Finland. We find the notion of final ecosystem goods and services (FEGS) operable, and suggest using it in economic valuation and other priority setting contexts, as well as in the selection of indicators. However, in the context of awareness raising it might be more effective to retain the well-established terminology of the Millennium Ecosystem Assessment. Our analysis shows that the cascade model (Potschin and Haines-Young, 2011. Progress in Physical Geography 35(5), 575-594) is helpful in distinguishing between ecosystem structures, processes, services, benefits and values by making the sequence of links visible. Johnston and Russell's (2011. Ecological Economics 70(12), 2243-2249) operational mechanism for determining FEGSs proves also instrumental in separating intermediate (e.g. carbon sequestration) and final ecosystem services (e.g. reduction of atmospheric carbon). However, we find their definition of importance, which is based on willingness to pay, too narrow. Furthermore, we favour the CICES approach, which defines ecosystem services as the direct contributions that ecosystems - whether natural or semi-natural - make to human well-being

#BlackLivesMatter: Intersectionality, Violence, and Socially Transformative Art

This paper is designed to elicit dialogue on the impact of the #Blacklivesmatter (BLM) movement and be a call to action in the wake of murder and sustained oppression of the Black body in America. The paper focuses on the intersectionality of the BLM movement using art, “racial” analysis, creative pedagogy, and the theatre of the oppressed. Included is a monologue of a mother whose child has been murdered by a “peace officer” that leads the audience on an emotional journey. In addition, sobering statistics of documented murders of Black transgender women are presented, as are the health effects of discrimination. The language of oppression and its use in the media are explored, as is a discussion of socially transformative art. Finally, recommendations are made to continue to use art and theatre as tools to raise awareness of injustice and to promote social resistance